1 mg / ml solution for infusion
glyceryl trinitrate
What Nitroglycerin Abcur is and what it is used for
Nitroglycerin Abcur is a vasodilator with rapid effect for intravenous infusion ( injection into a vein). Nitroglycerin Abcur is used in case of hypoxia in the heart muscle, heart failure , acute high blood pressure and in operations to keep the blood pressure at a low level in a controlled manner.
Glyceryl trinitrate contained in Nitroglycerin Abcur may also be approved for the treatment of other conditions not mentioned in this leaflet. Ask your doctor, pharmacist or other healthcare professional if you have any further questions and always follow their instructions.
What you need to know before you use Nitroglycerin Abcur
Do not use Nitroglycerin Abcur
- if you are allergic to glyceryl trinitrate or any of the other ingredients of this medicine (listed in section 6)
- if you are taking medicines containing sildenafil (for impotence )
- if you have fluid in your pericardium ( pericardial tamponade )
- if you have pericarditis (constrictive pericarditis)
Warnings and cautions
Talk to your doctor, pharmacist or nurse before using Nitroglycerin Abcur if you have:
- low blood pressure
- disease of the blood vessels of the brain
- increased pressure in the brain
- constrictions in the heart valves
- anemia
- cardiac muscle thickening
- lack of oxygenation of the blood
- impaired thyroid function
Other medicines and Nitroglycerin Abcur
Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines.
The effect can be affected if you take Nitroglycerin Abcur at the same time as:
- agents containing sildenafil (for impotence ). You may suffer a severe drop in blood pressure, heart attack and circulatory disorders that can cause permanent damage to the heart and brain.
- heparin , a blood thinner
- vasodilators or antihypertensives
- alteplas, a medicine for blood clots
Pregnancy and breastfeeding
If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.
Pregnancy
Limited experience of use during pregnancy.
Breast-feeding
It is unknown whether Nitroglycerin Abcur is excreted in human milk.
Driving and using machines
Because you may become dizzy when treated with Nitroglycerin Abcur, your ability to react may be affected. You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention. One of the factors that can affect your ability in these respects is the use of drugs due to their effects and / or side effects . Descriptions of these effects and side effects can be found in other sections. Read all the information in this leaflet for guidance. If you are not sure, talk to your doctor or pharmacist.
Nitroglycerin Abcur contains glucose
Each ml of Nitroglycerin Abcur contains 46.36 mg of glucose . This should be considered by patients with diabetes mellitus .
How to use Nitroglycerin Abcur
Your doctor or nurse will give you Nitroglycerin Abcur in a vein ( intravenously ). Your doctor will decide the right dose for you and when and how an injection should be given.
If you use more Nitroglycerin Abcur than you should
Signs that you have received too much Nitroglycerin Abcur are headache, elation, reddening of the skin, cold sweats, vomiting, dizziness, fainting, heart rhythm disturbances, palpitations and drops in blood pressure.
This is unlikely to happen because you are receiving the medicine in a hospital.
Possible side effects
Like all medicines, this medicine can cause side effects , although not everybody gets them.
Common (may affect up to 1 in 10 people): headache, dizziness, palpitations, low blood pressure , flushing
Uncommon (may affect up to 1 in 100 people ): nausea
Rare ( may affect up to 1 in 1,000 people ): methemoglobinemia (blood disease), fainting
How to store Nitroglycerin Abcur
Keep this medicine out of the sight and reach of children.
No special storage instructions
Do not use this medicine after the expiry date which is stated on the carton after EXP. The expiration date is the last day of the specified month.
Medicines should not be disposed of via wastewater. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.
Contents of the package and other information
Content declaration
- The active substance is glyceryl trinitrate .
- The other ingredients are glucose monohydrate, hydrochloric acid to pH adjustment 3.0-4.0, water for injections.
What the medicine looks like and contents of the pack
50 ml in clear vials (glass, type II): packs of 1, 5, 10, 20, 25, or 50 vials.
Not all pack sizes may be marketed.
Marketing Authorisation Holder
Abcur AB
Box 1452
251 41 Helsingborg
Manufacturer
Solupharm GmbH
Industriestr. 3
34212 Melsungen
Germany
Millmount Healthcare Ltd.
Block-7, City North Business Campus,
Stamullen, Co. Meath,
Ireland