0.1% cream, ointment, and cutaneous solution
hydrocortisone butyrate
What Locoid is and what it is used for
Locoid is a medium-strength cortisone drug ( glucocorticoid ), which counteracts inflammation and has an antipruritic effect.
Locoid is used to treat acute and chronic eczema and psoriasis.
It is used to treat adults, children, and infants over 6 months.
Locoid cutaneous solution is also used for inflammation of the ear canal (external otitis ).
What you need to know before using Locoid
Do not use Locoid:
- if you are hypersensitive (allergic) to hydrocortisone butyrate or any of the other ingredients of Locoid
- in acne
- rosacea (a skin condition that causes redness , lumps and blisters on the face)
- in case of rash around the mouth ( oral dermatitis )
- in case of skin infection that is not treated at the same time
- in case of wounds on the skin
- Locoid cutaneous solution should not be used if the eardrum is punctured.
Warnings and cautions
Talk to your doctor, pharmacist, or nurse before using Locoid.
- Avoid getting Locoid in your eyes.
- Bandages should be avoided in case of infected eczema .
- There is an increased risk of side effects when treating areas where skin is against skin, e.g. armpits, groin, large skin areas, or under bandages, but also with frequent dosing or with long-term treatment.
- Be careful when using on the face and genitals, as these areas are more sensitive to cortisone than other skin areas.
- Hands should be washed after each use, unless Locoid is used to treat the hands.
- At the end of treatment, the skin problems may return in enhanced form (so-called rebound effect ).
- Contact a doctor if you experience blurred vision or other visual disturbances.
Children
Do not use it on children under 6 months.
Children usually need a shorter treatment time than adults.
Long-term treatment in children under 12 years of age should be avoided if possible.
Children have an increased risk of side effects when using cortisone drugs on the skin.
Diapers can act as a cover bandage which can increase Locoid uptake into the skin and thus increase the risk of side effects.
Pregnancy and breastfeeding
If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.
Pregnancy
There is a risk that Locoid affects the fetus and should therefore only be used if the benefit to the mother outweighs the risks to the baby. The doctor will assess this.
Breast-feeding
Locoid can be used during breastfeeding, but to avoid the baby accidentally getting the medicine in the mouth, it should not be used directly on the breasts.
Driving and using machines
Locoid does not affect the ability to drive or use machines.
Locoid cream contains cetostearyl alcohol, propyl parahydroxybenzoate (E216) and butyl parahydroxybenzoate
Locoid cream contains cetostearyl alcohol which may cause local skin reactions (eg contact dermatitis) as well as propyl parahydroxybenzoate (E216) and butyl parahydroxybenzoate which may cause an allergic reaction (possibly delayed).
How to use Locoid
Always use this medicine exactly as your doctor has told you. Ask your doctor or pharmacist if you are unsure.
Adults and children
A thin and even layer is applied 1-2 times daily on affected skin areas. The treatment is gradually reduced.
In case of inflammation in the ear canal, a Locoid cutaneous solution is dropped into the ear according to the doctor’s prescription.
Hands should be washed after each use unless Locoid is used to treat the hands.
Children
Regular daily use for longer than four weeks is not recommended for children. The treatment time should not exceed 7 days in infants. When the skin problems have improved, the number of coats should be reduced and treated in the shortest possible time.
Use of different forms of medicine
Locoid cream: exfoliating skin diseases
Locoid ointment: dry, scaly skin diseases
Locoid cutaneous solution: skin diseases in hairy regions
Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them.
Uncommon (may affect up to 1 in 100 people):
- New infection that occurs before the first infection has healed
- Knottror
- Redness and blisters on the face.
Rare (may affect up to 1 in 1,000 people):
- Effects on adrenal cortex (may manifest as fatigue, dizziness and nausea)
- Allergic reactions
- Skin thinning
- Dilation of small blood vessels in the skin
- White streaks on the skin
- Acne
- Rash around the mouth
- Rebound effect (disease symptoms worsen when treatment is stopped)
- Pigment changes
- Increased hair
- Skin inflammations
- Eczema (including contact dermatitis).
Has been reported (occurs in an unknown number of users):
- Skin infections
- Dimsyn
- Itching
- Reddening of the skin
- Rash
- Pain at the application site.
How to store Locoid
Keep this medicine out of the sight and reach of children.
Do not store above 25 ° C.
Locoid cream should be stored in protection against the cold and must not be frozen.
Do not use this medicine after the expiry date which is stated on the carton.
Locoid cream and ointment: Opened tube should be used within 6 months.
Locoid cutaneous solution: The opened bottle should be used within 8 weeks.
It may be a good idea to note the date when the tube/bottle is opened on the carton.
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.
Contents of the pack and other information
Content declaration
- The active substance is hydrocortisone butyrate. 1 gram of cream , ointment or cutaneous solution contains 1 mg of hydrocortisone (as butyrate).
- Other ingredients in:
- Locoid cream is cetostearyl alcohol, macrogol cetostearyl ether, liquid paraffin, white petrolatum, anhydrous citric acid, anhydrous sodium citrate and purified water. Preservatives: propyl parahydroxybenzoate E 216 and butyl parahydroxybenzoate.
- Locoid ointment is polyethylene and liquid paraffin.
- Locoid cutaneous solution is glycerol , povidone, anhydrous citric acid, anhydrous sodium citrate, isopropyl alcohol and purified water.
What the medicine looks like and contents of the pack
Locoid cream: 30 g, 50 g, and 100 g tube.
Locoid ointment: 30 g and 100 g tube.
Locoid cutaneous solution: 30 ml, 100 ml, and 250 ml plastic bottle.
Not all pack sizes may be marketed.
Marketing Authorization Holder and Manufacturer
Marketing Authorisation Holder
CHEPLAPHARM Arzneimittel GmbH
Ziegelhof 24
17489 Greifswald
Germany
Manufacturer
Temmler Italia SRL,
Via delle Industrie 2,
20061, Carugate (MI),
Italy