Erbitux – Cetuximab uses, dose and side effects
Erbitux contains cetuximab, a monoclonal antibody. Monoclonal antibodies are proteins that specifically recognize and bind to other unique proteins called antigens. Cetuximab binds to the epidermal growth factor receptor (EGFR), an antigen found on the surface of certain cancer cells. EGFR activates proteins called RAS. RAS proteins play an important role in EGFR’s signaling pathway – a complex signaling cascade involved in the development and progression of cancer. This binding means that the cancer cell can no longer receive the signals it needs for growth, survival, and spread.
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