What Thacapzol is and what it is used for
Thacapzol contains a substance that accumulates in the thyroid gland and strongly inhibits the thyroid gland’s production of hormones. Overproduction of thyroid hormone occurs in some forms of goiter.
Thacapzol is used for increased hormone secretion from the thyroid gland ( hyperthyroidism ).
What you need to know before you take Thacapzol
Do not take Thacapzol
– if you are allergic to thiamazole or any other ingredient in this medicine (listed in section 6).
– if you previously had inflammation of the pancreas ( acute pancreatitis ) after receiving thiamazole or carbimazole.
Warnings and precautions
In case of fever, sore throat, or another serious infectious disease, a doctor must be contacted immediately for a possible blood test.
Thacapzol can cause harm to an unborn baby. If you can become pregnant, use reliable contraception from the time you start treatment and during treatment.
Tell your doctor immediately if you develop a fever or abdominal pain, which may be signs of inflammation of the pancreas ( acute pancreatitis ). The use of Thacapzol may need to be discontinued.
Children and young people
Thacapzol is not recommended for children under 2 years of age.
Other medicines and Thacapzol
The effect of the treatment may be affected if this medicine and certain other medicines are taken at the same time. Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.
Pregnancy, breastfeeding, and fertility
If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before using this medicine.
There is a risk that the fetus or nursing child will be affected.
Thacapzol can cause harm to an unborn baby.
If you can become pregnant, use reliable contraception from the time you start treatment and during treatment.
If you are pregnant, think you may be pregnant, or are planning to have a baby, tell your doctor right away. Your treatment with Thacapzol may need to be continued during pregnancy if the benefit of the treatment is greater than the possible risk to you and your unborn child.
Driving ability and use of machinery
No effects on the ability to drive and use machines have been observed.
You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires increased attention. One of the factors that can affect your ability in these respects is the use of drugs due to their effects and/or side effects. A description of these effects and side effects can be found in other sections. Read all the information in this leaflet for guidance. Discuss with a doctor or pharmacist if you are unsure.
Thacapzol contains lactose
If you have an intolerance to some sugars, you should consult your doctor before taking this medicine.
How to take Thacapzol
Always take this medicine as directed by your doctor. Ask your doctor or pharmacist if you are unsure.
The dose is determined by the doctor, who adjusts it individually for you.
Adults
For long-term treatment, a starting dose of 1-4 tablets 2 times daily is recommended. The starting dose should be adapted to the activity of the disease.
Children and young people (3-17 years)
The starting dose is usually 0.5 mg/kg body weight, divided into 2 or 3 equal doses. The total daily dose of thiamazole should not exceed 40 mg.
Children 2 years and younger
Thacapzol is not recommended for children under 2 years of age.
If you have taken too much Thacapzol
If you have ingested too much medicine or if, for example, a child has ingested the medicine by mistake, contact a doctor or hospital for an assessment of the risk and advice.
If you forget to take Thacapzol
Do not take a double dose to make up for a missed tablet.
Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them.
In less common cases, Thacapzol can affect the white blood cells so that the defense against infection deteriorates. If you get an infection with symptoms such as fever with a greatly worsened general condition or fever with local infection symptoms such as sore throat/pharynx/mouth or vomiting, you should see a doctor as soon as possible so that a lack of white blood cells ( agranulocytosis ) can be ruled out via a blood test. It is important that you then information about your medication.
Common (affects more than 1 in 100 users): Rash and hives, arthritis. The effect on the bone marrow results ithe n reduced formation of different types of blood cells.
Uncommon (may affect up to 1 in 100 people): Liver damage
Rare (may affect up to 1 in 1,000 people): Loss of taste. Skin and mucous membrane inflammation. Vascular inflammation
Has been reported (occurring in an unknown number of users): Insulin autoimmune syndrome (syndrome with episodes of low blood sugar). Inflammation of the pancreas ( acute pancreatitis ).
How to store Thacapzol
Keep this medicine out of the sight and reach of children.
Store in the original packaging (light sensitive).
Use before the expiry date stated on the label after EXP. The expiration date is the last day of the specified month.
Medicines must not be thrown into the drain or among the household waste. Ask the pharmacist how to dispose of medications that are no longer used. These measures will help to protect the environment.
Contents of the packaging and other information
Contents declaration
– The active substance is thiamazole 5 mg per tablet
– Other ingredients are lactose monohydrate, microcrystalline cellulose, magnesium stearate, and anhydrous colloidal silicon dioxide.
Appearance and package sizes of the medicine
Thacapzol 5 mg tablets are white, round, flat with a partial score, debossed with TH within arcs, diameter 6 mm.
Plastic jar containing 100 tablets.
Marketing Authorisation Holder:
Meda AB
Box 906
170 09 Solna
Phone: 08-630 1900