10 mg tablets
What does Mytelase contain?
1 tablet contains 10 mg of active substance ambenone chloride.
The other ingredients are lactose 31 mg, corn starch, calcium hydrogen phosphate, and magnesium stearate.
The tablets are white, round, marked with MYT on one side, and scored on the other side.
How does Mytelase work?
Mytelase enhances the transmission of nerve impulses from nerve fibers to muscles. In myasthenia gravis, this transmission is weakened because the receptors ( receptors ) for the neurotransmitter acetylcholine are damaged. Mytelase reduces the breakdown of acetylcholine and the concentration increases, which improves the transmission of nerve impulses.
Mytelase has a long duration of action. Some effect remains in the morning if the evening dose is taken late, which is beneficial for those who have difficulty swallowing in the morning.
Information is provided by
Sanofi AB, Box 30052, 104 25 Stockholm
Manufacturer: Sofarimex Industria Química e Pharmacêutica Lda, Cacem, Portugal
What is Mytelase used for?
Mytelase tablets are used for myasthenia gravis (severe muscle weakness).
When should Mytelase not be used?
In case of hypersensitivity to any of the constituents of the tablet.
Things to think about before and when Mytelase is used
Those with the following conditions should consult a physician before starting treatment with Mytelase: asthma, Parkinson’s disease, intestinal or urinary tract obstruction, heart problems. The same applies if you use atropine-like medicine, so-called ganglion blocking agents (eg certain muscle relaxants or antihypertensive agents), or other medicines for myasthenia gravis.
Pregnancy
Limited experience of use during pregnancy. Therefore, consult a doctor before using Mytelase during pregnancy.
Breast-feeding
It is unknown whether ambenone chloride is excreted in human milk. Therefore, consult your doctor before using Mytelase during breastfeeding.
What should you avoid when using Mytelase?
Treatment may be affected if this medicine is taken at the same time as certain other medicines. The treating physician, therefore, needs to know about other concomitant medication.
See “Things to consider before and when Mytelase is used”.
How should Mytelase be used?
Dosage instructions
Dose one is determined by the doctor, who adjusts it individually for you.
Each patient, in collaboration with the doctor, must gradually test to the correct dose and pay attention to overdose symptoms (see Side effects ). The treatment is started with a dose of ½ tablet (5 mg) 3-4 times a day, and then gradually increased until a satisfactory effect is obtained. Some patients need 25 tablets (250 mg) or more per day. If more than 15 tablets (150 mg) are required per day, a dose adjustment should be made in a hospital.
What to do if you take too large a dose?
If you have taken too much medicine, always contact a doctor or hospital.
Side effects
Most common (may affect up to 1 in 10 people): Increased salivation, pupillary reduction, increased tear flow, reddening of the skin, sweating, feeling hot, slow pulse, convulsions in the trachea.
Uncommon/rare (may affect up to 1 in 100 people): Stomach cramps, diarrhea, nausea, vomiting, increased secretion of mucus from the trachea. Severe overdose can cause similar muscle weakness as the disease itself. Muscle twitching and cramps can also occur, as well as paleness, frequent urination, headaches, irritation, anxiety, and confusion. Mental side effects can occur but are rare.
Has been reported (frequency can not be calculated from the available data): disturbance of the electrical impulses of the heart, general malaise with anxiety, and dizziness.
Storage and durability
Do not use this medicine after the expiry date which is stated on the carton.
Leftover or too old medicine can be left at the pharmacy for destruction.