Irbesartan / Hydrochlorothiazide Actavis – Hydrochlorothiazide uses, dose and side effects
Irbesartan / Hydrochlorothiazide Actavis is a combination of two active substances, irbesartan and hydrochlorothiazide . Irbesartan belongs to a group of medicines called angiotensin -II receptor antagonists. Angiotensin -II is a substance, which is produced in the body, and which binds to certain structures ( receptors ) in the blood vessels and causes them to constrict. This leads to increased blood pressure. Irbesartan prevents the binding of angiotensin -II to these receptors, causing the blood vessels to relax and the blood pressure to drop. Hydrochlorothiazide belongs to a group of medicines (called thiazide diuretics) that increase urine excretion and thereby lower blood pressure. The two active substances in Irbesartan / Hydrochlorothiazide Actavis work together to lower blood pressure more than if you have only given one of the substances.
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