0.5 mg / ml + 2.5 mg / ml solution for injection
glycopyrronium bromide, neostigmine methyl sulfate
What Robinul-Neostigmine is and what it is used for
Robinul-Neostigmine is used in connection with surgery to cancel the effect of muscle relaxants.
What you need to know before using Robinul-Neostigmine
Do not use Robinul-Neostigmine
- if you are allergic to the active substances or any of the other ingredients of this medicine (listed in section 6).
- if you have any type of obstruction in the gastrointestinal tract or urinary tract.
Warnings and cautions
Talk to your doctor or pharmacist before receiving Robinul-Neostigmine if you have:
- glaucoma ( glaucoma )
- heart disease
- intestinal disease
- high blood pressure
- thyrotoxicosis ( toxic goiter )
This medicine contains less than 1 mmol (23 mg) sodium per 1 ml glass ampoule, ie essentially ‘sodium-free’.
Other medicines and Robinul-Neostigmine
Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.
Pregnancy, breastfeeding, and fertility
If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.
Clinical experience in pregnant women is limited.
Glycopyrronium bromide passes into breast milk, but the risk of effects on the baby seems unlikely with therapeutic doses. There is no information on whether neostigmine passes into breast milk.
How to use Robinul-Neostigmine
The dose you receive is determined by your doctor. Robinul-Neostigmine is given by healthcare professionals as an injection into a blood vessel (a vein) under anesthesia.
Use for children and adolescents
The doctor decides which dose to give.
If you have any further questions on the use of this product, ask your doctor, pharmacist, or nurse.
Possible side effects
Contact a doctor immediately if you experience any of the following symptoms, as you may then need emergency care.
Swelling mainly of the face, lips, or throat, which may make it difficult to swallow or breathe, itching and rash. This may be a sign of a severe allergic reaction or angioedema (no known frequency, can not be calculated from the available data).
Like all medicines, this medicine can cause side effects, although not everybody gets them.
Common (may affect up to 1 in 10 people):
- Fast or slow heartbeat, arrhythmia.
- Dry mouth increased salivation.
- Increased activity in the gastrointestinal tract.
- Reduced sweating.
Uncommon (may affect up to 1 in 100 people):
- Difficulty urinating.
- Visual disturbances.
Rare (may affect up to 1 in 1,000 people):
- Severe allergic reaction.
- Severe heart problems.
- Low blood pressure.
How to store Robinul-Neostigmine
Keep this medicine out of the sight and reach of children.
Sensitive to light. Store in the outer carton.
Do not use this medicine after the expiry date which is stated on the carton. The expiration date is the last day of the specified month
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.
6. Contents of the pack and other information
- The active substances are 0.5 mg / ml glycopyrronium bromide and 2.5 mg / ml neostigmine methyl sulphate.
- The other ingredients are disodium phosphate dodecahydrate, citric acid, sodium hydroxide, and water for injections.
What the medicine looks like and the contents of the pack
Glass ampoule is. Pack size: 10 x 1 ml.
Marketing Authorization Holder and Manufacturer
170 09 Solna
Tel: 08-630 19 00