Infusion solution

What Ringerfundin is and what it is used for

Ringer’s fundus is an infusion fluid , a solution given in a vein.

Ringerfundin is used to replace fluid loss in the blood circulation.
Ringerfundin can be used in conditions where you can get or have received something too high acidity in the blood.

What you need to know before using Ringerfundin

Ringerfundin should not be given if you have

  • the increased blood volume in the body
  • severe heart disease with shortness of breath and swelling of the legs and feet
  • severe kidney disease and inability or near inability to urinate
  • tissue swelling due to accumulation of fluid in the body
  • high potassium – or calcium content in the blood
  • too much acidity in the blood ( alkalosis ).

Warnings and cautions

Talk to your doctor or pharmacist before using Ringerfundin.

Take special care with Ringerfundin if you have any

  • any disease where it is necessary to limit the intake of salt, e.g. mild or moderate impaired cardiac function, tissue swelling or fluid accumulation in the lungs
  • sarcoidosis (a chronic disease of the immune system affecting the lymph nodes and connective tissue)
  • mild to moderate increase in blood pressure
  • acute fluid loss e.g. after extensive tissue damage such as in severe burns or due to impaired adrenal function
  • high sodium or chloride content in the blood
  • eclampsia (a complication associated with pregnancy)
  • mild to moderate renal impairment
  • breathing difficulties
  • any disease or medication that may lead to reduced sodium excretion.

If any of the above applies to you, your doctor will decide if this solution is right for you.

The fluid balance in your body and the salt balance in your blood are checked during treatment with Ringerfundin to ensure that the balance is kept normal.

Other medicines and Ringerfundin

Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines.

In particular, remember to mention if you are taking, using or receiving the following medicines:

  • Drugs that bind sodium or water in the body, such as
    • steroid hormones or
    • carbenoxolone
      If these medicines are used at the same time as Ringerfundin, the level of fluid in the body and the level of sodium in the blood may increase, leading to swelling and an increase in blood pressure.
  • Drugs that affect the potassium content of the blood, such as
    • suxameton
    • certain diuretics ( diuretics ), which reduce potassium excretion, e.g. amiloride, spironolactone , triamterene
    • tacrolimus, ciclosporin (medicine used to prevent organ rejection in organ transplantation)
      If these medicines are used at the same time as Ringerfundin, the potassium level in the blood may increase, which can cause side effects in the function of the heart. This is more likely if you have impaired kidney function.
  • Digitalis drugs (eg digoxin ) used in heart disease
    Their effect can increase when the calcium content in the blood increases, which can lead to side effects , such as irregular heartbeat. Therefore, your doctor may need to change the dosage one of digoxin .
  • Vitamin D which can increase the calcium level in the blood.

The doctor is aware of these side effects that may occur if Ringerfundin and the above mentioned medicines are combined. Your doctor will make sure you get the right dose .

Some medicines must not be mixed with Ringerfundin. The doctor knows who they are and uses only those medicines that can be safely mixed.

Pregnancy and breastfeeding

If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.
Your doctor will decide if you can get this solution during pregnancy.
This medicine should be used with caution in connection with pregnancy poisoning, a complication that can occur during pregnancy.

Driving and using machines

Ringerfundin does not affect the ability to drive or use machines.

Ringerfundin contains sodium

If you have a low-salt diet, note that this medicine contains 145 mmol sodium per 1000 ml.

How to use Ringerfundin

Method of administration
This drug is given into a vein via a drip.

Dosage Your
doctor will decide what dose you need. The normal dose for adults, the elderly and adolescents is 500 milliliters – 3 liters per day. The usual dose for infants and children is 20 – 100 ml / kg / day.

Speed ​​of administration
Your doctor will decide how fast to infuse depending on your weight and condition.

Duration of treatment Your
doctor will decide how long you need to receive this infusion solution .

While you are receiving infusion one, the fluid and salt balance in your body and the acid-base balance in your blood are checked.

If you take more Ringerfundin than you should:

It is unlikely that you will receive too much, as healthcare professionals monitor that you receive the correct amount of Ringerfundin.

If you accidentally take too much or if the solution is given too quickly, the following symptoms may occur:

  • increased skin tension
  • narrowing of the veins and swelling
  • accumulation of fluid in the lungs
  • respiratory distress
  • disturbances in the body’s fluid and salt balance.

Very high levels of the individual components of Ringerfundin in the blood cause specific symptoms that the doctor will monitor.

Should you show signs of overdose, your healthcare provider will discontinue the infusion immediately. The treatment depends on what symptoms you have.

If you have any further questions on the use of this product, ask your doctor or pharmacist.

Possible side effects

Like all medicines, this medicine can cause side effects, although not everybody gets them.

Some side effects are caused by the way the medicine is given. It can e.g. be fever, injection site infection, local pain or reaction, venous irritation, blood clot, or inflammation of the veins starting at the injection site.

Hypersensitivity reactions to magnesium salts in the solution characterized by rash have sometimes occurred. For these reactions, the frequency can not be calculated from the available data.

Intestinal paralysis has been reported rarely following infusion of magnesium sulphate (may affect up to 1 in 100 people).

How to store the Ringerfundin

Keep this medicine out of the sight and reach of children.
Glass bottles and plastic bottles made of polyethylene: Store in protection against the cold. Do not freeze.
Plastic bags: Do not store above 25 ° C. Store in a cold place. Do not freeze.

This medicine will not be used if the solution contains particles or if the solution is cloudy or discolored. The preparation will not be used if the packaging is leaking or damaged.

This medicine is for single use only. Started packaging must not be reused.

Do not use this medicine after the expiry date which is stated on the label or carton after EXP.

Contents of the pack and other information

Content declaration

The active substances in Ringerfundin solution for infusion :

1000 ml infusion solution contains:
chloride Potassium chloride
Magnesium chloride hexahydrate
Calcium chloride
dihydrate Sodium acetate
trihydrate Malic acid
6.8 g
0.3 g
0.2 g
0.37 g
3.27 g
0.67 g

The other ingredients are:
Water for injections, sodium hydroxide (for pH regulation )

What the medicine looks like and the contents of the pack

Ringer’s fundus is an infusion solution (given into a vein via a drip). The solution is clear and colorless.


  • Plastic bottles containing 250 ml, 500 ml, or 1,000 ml, in packs of 1 or 10 bottles
  • Plastic bags containing 250 ml, 500 ml or 1,000 ml, in packs of 1 or 20 bags (250 ml and 500 ml) or 1 or 10 bags (1,000 ml)
  • Glass bottles containing 250 ml, 500 ml or 1,000 ml, in packs of 1 or 10 bottles (250 ml and 500 ml) or 1 or 6 bottles (1,000 ml)

Not all pack sizes may be marketed.

Marketing Authorisation Holder

B. Braun Melsungen AG
Carl-Braun-Strasse 1
34212 Melsungen

Postal address:
34209 Melsungen

Tel .: + 49-5661-71-0
Fax: + 49-5661-71-4567


B. Braun Melsungen AG
Carl-Braun-Strasse 1
34212 Melsungen, Germany

B. Braun Medical SA
Carretera de Terrassa, 121
08191 Rubi (Barcelona), Spain

B. Braun Avitum AG

Schwarzenberger Weg 73-79

34212 Melsungen, Germany

This medicinal product is authorized under the European Economic Area under the names:

Austria Sterofundin ISO infusion solution
Belgium Sterofundin ISO solution for infusion
Bulgaria Sterofundin ISO
Cyprus Sterofundin ISO
Czech Republic Ringerfundin B.Braun
Denmark The ringer meeting
Estonia Sterofundin ISO
Finland Ringerfundin infusion tea, liuos
France Isofundine, perfusion solution
Germany Sterofundin ISO infusion solution
Greece Sterofundin ISO
Hungary Ringerfundin B.Braun infusion
Italy Sterofundin
Latvia Sterofundin ISO
Lithuania Sterofundin ISO infuzinis tirpalas
Luxembourg Sterofundin ISO solution for perfusion
Malta Sterofundin ISO
Netherlands Sterofundin ISO
Norway Ringerfundin infusion solution
Poland Sterofundin ISO
Portugal Isofundin
Romania Sterofundin ISO searchable solution
Slovenia Sterofundin ISO raztopina za infundiranje
Slovakia The ringer meeting
Spain Isofundin, a solution for perfusion
Sweden Ringerfundin infusion solution
United Kingdom Sterofundin ISO solution for infusion

Muhammad Nadeem

Leave a Reply