5 mg metolazone tablets
What Metolazon Abcur is and what it is used for
Metalozan Abcur is a diuretic that contains the active substance metolazone. Metolazone Abcur is used to treat edema (fluid retention) in kidney disease when other treatments do not work.
Metolazone contained in Metolazon Abcur may also be approved for the treatment of other conditions not mentioned in this product information. Ask your doctor, pharmacist, or another healthcare professional if you have any further questions, and always follow their instructions.
What you need to know before you take Metolazon Abcur
Do not take Metolazon Abcur
- if you are allergic to metolazone or any of the other ingredients of this medicine (listed in section 6)
- if you have had an allergic reaction while using diuretics that belong to a group called sulfonamides or thiazides
- if you can not urinate
- in coma or coma-like conditions caused by liver cirrhosis
- if you have a severe disturbance of the electrolyte balance in the blood
Warnings and cautions
Talk to your doctor or pharmacist before taking Metolazon Abdur.
- if you have any other illness, especially kidney disease, diabetes or rheumatism. Then inform your doctor about the disease.
- if you get an infection with symptoms such as fever with severely deteriorating general condition or fever with local infection symptoms such as sore throat / throat / mouth or difficulty urinating. You should then see a doctor as soon as possible. Metolazone Abcur may in rare cases affect the white blood cells so that the defense against infection deteriorates. A blood sample is taken to rule out a lack of white blood cells ( agranulocytosis ). It is important that you inform your doctor about your medication.
- if you are going to have surgery, your dose of Metolazon Abcur must be carefully adjusted. Tell your doctor that you are having surgery.
- if you experience impaired vision or eye pain. This may be a symptom of fluid accumulation in the eye (between the choroid and retina) or an increase in pressure in the eye and may occur within a few hours to weeks after taking Metolazon Abcur. This can lead to permanent vision loss if left untreated. If you have previously had an allergy to penicillin or sulfonamide, you may be at higher risk of developing this condition.
Other medicines and Metolazon Abcur
Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines. You should tell your doctor about other medicines that you are taking (including herbal medicines). This is especially important for the following medicines:
- lithium (used to treat a specific type of depression)
- digoxin (used to treat heart problems)
- non-steroidal anti-inflammatory drugs (used to treat pain, fever and inflammation )
- ciclosporin (a medicine that affects the immune system)
- diuretics ( diuretics other than Metolazone Abcur; used to treat kidney disease, high blood pressure , heart failure and liver cirrhosis )
- ACE inhibitor (used to treat high blood pressure and heart failure )
- warfarin (used to prevent blood clotting)
- insulin or oral antidiabetics
- corticosteroid is
- ACTH ( hormone produced by the pituitary gland )
- sotalol (used to treat heart disease and high blood pressure )
- barbiturates (used to treat sleep problems, anxiety and epilepsy )
- angiotensin -II- antagonist (used to treat high blood pressure , heart failure and kidney damage due to diabetes )
Metolazon Abcur with food, drink and alcohol
If you take Metolazon Abcur with alcohol, your blood pressure may drop and you may feel dizzy, weak, and tired.
You should take the tablet at the same meal every day, eg breakfast.
Pregnancy and breastfeeding
If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.
You should not use Metolazon Abcur during pregnancy or breastfeeding.
Driving and using machines
There are no studies on the ability to drive or use machines when using Metolazon Abdur. Treatment with Metolazon Abcur can cause effects that may affect your ability to drive or use machines, such as fatigue and dizziness. If you feel tired or drowsy, do not drive or use machines.
You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention. One of the factors that can affect your ability in these respects is the use of drugs due to their effects and/or side effects. Descriptions of these effects and side effects can be found in other sections. Read all the information in this leaflet for guidance. If you are not sure, talk to your doctor or pharmacist.
Metolazone Abcur contains lactose monohydrate and sodium
If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.
This medicine contains less than 1 mmol (23 mg) sodium per tablet, ie essentially ‘sodium-free’.
Possible side effects
Like all medicines, this medicine can cause side effects, although not everybody gets them.
Stop taking Metolazon Abcur and contact a doctor immediately or see your nearest emergency department if you experience any of the following symptoms:
Rare (may affect up to 1 in 1,000 people)
- Influenza-like symptoms , sore throat / pharynx / mouth or difficulty urinating. This can be caused by a decrease in white blood cells ( agranulocytosis ).
- Severe skin reaction, which begins with painful redness of the skin which then develops into large blisters and skin detachment ( toxic epidermal necrolysis ).
Has been reported (occurs in an unknown number of users)
- Decreased vision or pain in the eyes due to high pressure (possible signs of fluid accumulation in the eye (between the choroid and retina) or acute narrow-angle glaucoma
Other side effects that may occur when using Metolazon Abcur:
Common (may affect up to 1 in 10 people)
- nausea, vomiting, constipation and diarrhea
- muscle cramps
- headache, dizziness and fatigue
- low levels of potassium , sodium and chloride in the blood
- high levels of uric acid , urea and creatinine and blood sugar
- glucose in the urineUncommon (may affect up to 1 in 100 people)
- decreased white blood cell count ( leukopenia )
- rash
- inflammation of the blood vessels
- goutRare (may affect up to 1 in 1,000 people)
- decreased number of red blood cells
- decreased platelet count
- high levels of calcium in the blood
- low levels of magnesium in the blood
- hepatitis or intrahepatic cholestasis
- kidney failure
How to store Metolazon Abcur
Keep this medicine out of the sight and reach of children.
Store in the original package. Sensitive to light.
Do not use this medicine after the expiry date which is stated on the carton after EXP. The expiration date is the last day of the specified month.
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.
Contents of the pack and other information
Content declaration
- The active substance is metolazone 5 mg.
- The other ingredients are croscarmellose sodium, microcrystalline cellulose, lactose monohydrate and sodium stearyl fumarate.
What the medicine looks like and contents of the pack
Metolazone Abcur tablets are round, flat, and white to off-white with beveled edges and a notch on one side. The tablet can be divided into two equal doses.
Metolazone Abcur is supplied in blister packs of 20, 28, 30, 50, 56, 60, 98, or 100 tablets. Not all pack sizes may be marketed.
Marketing Authorisation Holder
Abcur AB
Box 1452
251 14 Helsingborg
Manufacturer
Formula Pharmazeutische und chemische Entwicklungs GmbH
Goerzallee 305 b
DE-14167 Berlin
Germany