{"id":9177,"date":"2021-03-26T11:30:33","date_gmt":"2021-03-26T11:30:33","guid":{"rendered":"https:\/\/zeepedia.com\/?p=9177"},"modified":"2021-04-12T10:37:09","modified_gmt":"2021-04-12T10:37:09","slug":"fycompa","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/fycompa\/","title":{"rendered":"Fycompa &#8211; Perampanel uses, dose and side effects"},"content":{"rendered":"\n<p> 2 mg, 4 mg, 6 mg, 8 mg, 10 mg and 12 mg&nbsp;film-coated tablets<br><strong>perampanel<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What Fycompa is and what it is used for<\/h2>\n\n\n\n<p>Fycompa contains the medicine perampanel.&nbsp;It belongs to a group of medicines called&nbsp;antiepileptics&nbsp;.&nbsp;These drugs are used to treat&nbsp;epilepsy&nbsp;, ie conditions when someone has repeated seizures (seizures).&nbsp;It has been prescribed for you by your doctor to reduce the number of seizures.<br><\/p>\n\n\n\n<p>Fycompa is used together with other medicines to treat&nbsp;epilepsy&nbsp;to treat some forms of epilepsy:<\/p>\n\n\n\n<p>In adults, adolescents (aged 12 years and older) and children (from 4 to 11 years)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>It is used to treat seizures that affect a part of the brain (a &#8220;partial seizure&#8221;).<\/li><li>These&nbsp;partial seizures&nbsp;can, but do not have to, be followed by seizures that affect the whole brain (a &#8220;secondary generalization&#8221;).<\/li><\/ul>\n\n\n\n<p>In adults, adolescents (aged 12 years and older) and children (from 7 to 11 years)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>It is also used to treat certain seizures that affect the whole brain from the beginning (called &#8220;generalized seizures&#8221;) and cause seizures or absenteeism attacks.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">2. What you need to know before taking Fycompa<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">DO NOT Fycompa:<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have ever had a severe rash or flaky skin, blisters and \/ or cold sores after taking the perampanel.<\/li><li>if you are allergic to perampanel or any of the other ingredients of this medicine (listed in section 6).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before taking Fycompa if you have liver problems or moderate or severe kidney problems.<br><\/p>\n\n\n\n<p>Do not take Fycompa if you have severe liver problems or moderate or severe kidney problems.<br><\/p>\n\n\n\n<p>Before taking this medicine, tell your doctor if you have a history of alcohol or drug addiction.<br><\/p>\n\n\n\n<p>Cases of elevated liver enzyme levels have been reported in some patients taking Fycompa in combination with other antiepileptic drugs.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Fycompa may make you feel dizzy or drowsy, especially at the beginning of treatment.<\/li><li>Fycompa may make you more likely to fall, especially if you are older, which may also be due to your illness.<\/li><li>Fycompa can make you aggressive, angry or violent.&nbsp;It can also cause you to experience unusual or extreme changes in your behavior or mood.<\/li><\/ul>\n\n\n\n<p>Talk to a doctor or pharmacist if any of these happen.<br><\/p>\n\n\n\n<p>Suicidal ideation and self-harm have been reported in a small number of patients treated with&nbsp;antiepileptic drugs&nbsp;.&nbsp;Contact your doctor immediately if you ever have such thoughts.<br><\/p>\n\n\n\n<p>Serious skin reactions including drug-&nbsp;side&nbsp;effects with&nbsp;eosinophilia&nbsp;and systemic symptoms (DRESS) and Stevens-Johnson syndrome (SJS) have been reported with the use of perampanel.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>DRESS most often, but not only, occurs as&nbsp;flu-like symptoms&nbsp;and rashes with body temperature above normal, elevated liver enzyme levels in blood tests and increased number of a type of&nbsp;white blood cell&nbsp;(&nbsp;eosinophilia&nbsp;) and enlarged&nbsp;lymph nodes&nbsp;.<\/li><li>Stevens-Johnson syndrome (SJS) can&nbsp;initially&nbsp;appear as reddish spots with a &#8220;target-like appearance&#8221; or circular rash on the torso, often with blisters in the middle.&nbsp;In addition, sores can occur on the mouth, throat, nose, genitals and eyes (red and swollen eyes).&nbsp;These severe skin rashes are often preceded by fever and \/ or&nbsp;flu-like symptoms&nbsp;.&nbsp;The rash can develop into extensive skin loss and life-threatening complications or be fatal.<\/li><\/ul>\n\n\n\n<p>If you experience any of the above after taking Fycompa (or if you are not sure) talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children<\/h2>\n\n\n\n<p>Fycompa is not recommended for children under 4 years.&nbsp;Safety and efficacy are not yet known in children under 4 years of age for&nbsp;partial seizures&nbsp;and under 7 years of age for&nbsp;generalized seizures&nbsp;.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Fycompa<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken or might take any other medicines.&nbsp;This also includes over-the-counter and herbal remedies.&nbsp;Fycompa in combination with other medicines can cause&nbsp;side effects&nbsp;or affect how the medicines work.&nbsp;Do not start or stop other drug treatments without first talking to a doctor or pharmacist.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Other medicines for&nbsp;epilepsy&nbsp;, e.g.&nbsp;carbamazepine, oxcarbazepine and&nbsp;phenytoin&nbsp;used to treat seizures may affect Fycompa.&nbsp;Tell your doctor if you are taking or have recently taken these medicines as your&nbsp;dose&nbsp;may need to be adjusted.<\/li><li>Felbamate (a medicine used to treat&nbsp;epilepsy&nbsp;) can also affect Fycompa.&nbsp;Tell your doctor if you are taking or have recently taken this medicine as your&nbsp;dose&nbsp;may need to be adjusted.<\/li><li>Midazolam (a medicine used to stop prolonged, acute (sudden) seizures, as a sedative and for insomnia) may be affected by Fycompa.&nbsp;Tell your doctor if you are taking midazolam as your&nbsp;dose&nbsp;may need to be adjusted.<\/li><li>Some other medicines like rifampicin (a medicine for bacterial&nbsp;infections&nbsp;), hypericum (&nbsp;St. John&#8217;s wort&nbsp;) (a medicine for mild anxiety) and&nbsp;ketoconazole&nbsp;(a medicine for fungal infections) may affect Fycompa.&nbsp;Tell your doctor if you are taking or have recently taken these medicines as your&nbsp;dose&nbsp;may need to be adjusted.<\/li><li>Hormonal contraceptives (including oral contraceptives,&nbsp;implants&nbsp;,&nbsp;injections&nbsp;and&nbsp;patches&nbsp;)<\/li><\/ul>\n\n\n\n<p>Tell your doctor if you are taking hormonal contraceptives.&nbsp;Fycompa may make certain hormonal contraceptives, such as levonorgestrel, less effective.&nbsp;You should use other types of safe and effective contraceptives (such as condoms or&nbsp;IUDs&nbsp;) when taking Fycompa.&nbsp;You should continue to do this for one month after stopping treatment.&nbsp;Discuss with your doctor which contraceptives are best for you.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Fycompa with alcohol<\/h2>\n\n\n\n<p>Talk to your doctor before drinking alcohol.&nbsp;Be careful with alcohol consumption when taking antiepileptic medicines such as Fycompa.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Drinking alcohol while taking Fycompa may make you less alert and affect your ability to drive or use tools or machines.<\/li><li>Alcohol with Fycompa can also aggravate feelings of anger, confusion and sadness.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor for advice before using this medicine.&nbsp;Do not stop treatment without first talking to your doctor.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Fycompa is not recommended during pregnancy.<\/li><li>You must use reliable contraception to avoid getting pregnant while you are being treated with Fycompa.&nbsp;You should continue to do this for one month after stopping treatment.&nbsp;Tell your doctor if you are taking hormonal contraceptives.&nbsp;Fycompa can make certain hormonal contraceptives, e.g.&nbsp;levonorgestrel, less effective.&nbsp;You should use other types of safe and effective contraceptives (such as condoms or&nbsp;IUDs&nbsp;) when taking Fycompa.&nbsp;You should continue to do this for one month after stopping treatment.&nbsp;Discuss with your doctor which contraceptives are best for you<\/li><\/ul>\n\n\n\n<p>There is no information on whether Fycompa&#8217;s ingredients can be transferred to breast milk.<\/p>\n\n\n\n<p>Your doctor will assess the benefits and risks of treatment with Fycompa in combination with breast-feeding for your baby.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Do not drive or use machines until you know how Fycompa affects you.<\/p>\n\n\n\n<p>You must talk to your doctor about the effect of your&nbsp;epilepsy&nbsp;on driving and using machines.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Fycompa may make you feel dizzy or drowsy, especially at the beginning of treatment.&nbsp;If this happens to you, do not drive or use any tools or machines.<\/li><li>If you drink alcohol while taking Fycompa, these effects may be exacerbated.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Fycompa contains lactose<\/h2>\n\n\n\n<p>Fycompa contains&nbsp;lactose&nbsp;(a sugar).&nbsp;If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. How to take Fycompa<\/h2>\n\n\n\n<p>Always take this medicine exactly as your doctor has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<br><\/p>\n\n\n\n<p><strong>How much medicine to take<\/strong><br><\/p>\n\n\n\n<p><strong>Adults and adolescents (aged 12 years and older) in the treatment of&nbsp;partial onset seizures&nbsp;and generalized seizures:<\/strong><\/p>\n\n\n\n<p>The starting dose is usually 2 mg once a day before bedtime.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Your doctor may increase the&nbsp;dose&nbsp;one by 2 mg at a time up to a maintenance dose of between 4 mg and 12 mg depending on how you respond to the increase.<\/li><li>If you have mild or moderate liver problems, do not take a&nbsp;dose&nbsp;higher&nbsp;than 8 mg per day and your dose increases should be made at least two weeks apart.<\/li><li>Do not take a higher&nbsp;dose&nbsp;of Fycompa than your doctor has prescribed.&nbsp;It may take a few weeks to find the right&nbsp;dose&nbsp;of Fycompa for you.<\/li><\/ul>\n\n\n\n<p>The table below summarizes the recommended&nbsp;doses&nbsp;for the treatment of&nbsp;partial seizures&nbsp;in children between 4 and 11 years of age and&nbsp;generalized seizures&nbsp;in children between 7 and 11 years of age.&nbsp;More information can be found under the table.<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><th scope=\"col\"><br><br><\/th><th scope=\"col\">Children weighing:<\/th><\/tr><tr><th scope=\"col\">More than 30 kg<\/th><th scope=\"col\">20 kg to less than 30 kg<\/th><th scope=\"col\">Less than 20 kg<\/th><\/tr><tr><td>Recommended starting dose<\/td><td>2 mg \/ day<\/td><td>1 mg \/ day<\/td><td>1 mg \/ day<\/td><\/tr><tr><td>Recommended maintenance dose<\/td><td>4-8 mg \/ day<\/td><td>4-6 mg \/ day<\/td><td>2-4 mg \/ day<\/td><\/tr><tr><td>Recommended maximum&nbsp;dose<\/td><td>12 mg \/ day<\/td><td>8 mg \/ day<\/td><td>6 mg \/ day<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p><strong>Children (from 4 to 11 years) weighing 30 kg or more in the treatment of partial seizures:<\/strong><\/p>\n\n\n\n<p>The starting dose is usually 2 mg once a day before bedtime.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Your doctor may increase the&nbsp;dose&nbsp;one by 2 mg at a time up to a maintenance dose of between 4 mg and 8 mg depending on how you respond to the treatment.&nbsp;Depending on the individual treatment response and how well you tolerate the medicine, the&nbsp;dose&nbsp;can be increased to a maximum&nbsp;dose&nbsp;of 12 mg \/ day.<\/li><li>If you have mild or moderate liver problems, do not take a&nbsp;dose&nbsp;higher&nbsp;than 4 mg per day and your dose increases should be made at least two weeks apart.<\/li><li>Do not take a higher&nbsp;dose&nbsp;of Fycompa than your doctor has prescribed.&nbsp;It may take a few weeks to find the right&nbsp;dose&nbsp;of Fycompa for you.<\/li><\/ul>\n\n\n\n<p><strong>Children (from 4 to 11 years) weighing 20 kg to less than 30 kg in the treatment of partial seizures:<\/strong><\/p>\n\n\n\n<p>The starting dose is usually 1 mg once a day before bedtime.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Your doctor may increase the&nbsp;dose&nbsp;one by 1 mg at a time up to a maintenance dose of between 4 mg and 6 mg depending on how you respond to the treatment.&nbsp;Depending on the individual treatment response and how well you tolerate the medicine, the&nbsp;dose&nbsp;can be increased to a maximum&nbsp;dose&nbsp;of 8 mg \/ day.<\/li><li>If you have mild or moderate liver problems, do not take a&nbsp;dose&nbsp;higher&nbsp;than 4 mg per day and your dose increases should be made at least two weeks apart.<\/li><li>Do not take a higher&nbsp;dose&nbsp;of Fycompa than your doctor has prescribed.&nbsp;It may take a few weeks to find the right&nbsp;dose&nbsp;of Fycompa for you.<\/li><\/ul>\n\n\n\n<p><strong>Children (from 4 to 11 years) weighing less than 20 kg in the treatment of partial seizures:<\/strong><\/p>\n\n\n\n<p>The starting dose is usually 1 mg once a day before bedtime.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Your doctor may increase the&nbsp;dose&nbsp;one by 1 mg at a time up to a maintenance dose of between 2 mg and 4 mg depending on how you respond to the treatment.&nbsp;Depending on the individual treatment response and how well you tolerate the medicine, the&nbsp;dose&nbsp;can be increased to a maximum&nbsp;dose&nbsp;of 6 mg \/ day.<\/li><li>If you have mild or moderate liver problems, do not take a&nbsp;dose&nbsp;higher&nbsp;than 4 mg per day and your dose increases should be made at least two weeks apart.<\/li><li>Do not take a higher&nbsp;dose&nbsp;of Fycompa than your doctor has prescribed.&nbsp;It may take a few weeks to find the right&nbsp;dose&nbsp;of Fycompa for you.<\/li><\/ul>\n\n\n\n<p><strong>Children (from 7 to 11 years of age) weighing 30 kg or more in the treatment of generalized seizures:<\/strong><\/p>\n\n\n\n<p>The starting dose is usually 2 mg once a day before bedtime.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Your doctor may increase the&nbsp;dose&nbsp;one by 2 mg at a time up to a maintenance dose of between 4 mg and 8 mg depending on how you respond to the treatment.&nbsp;Depending on the individual treatment response and how well you tolerate the medicine, the&nbsp;dose&nbsp;can be increased to a maximum&nbsp;dose&nbsp;of 12 mg \/ day.<\/li><li>If you have mild or moderate liver problems, do not take a&nbsp;dose&nbsp;higher&nbsp;than 4 mg per day and your dose increases should be made at least two weeks apart.<\/li><li>Do not take a higher&nbsp;dose&nbsp;of Fycompa than your doctor has prescribed.&nbsp;It may take a few weeks to find the right&nbsp;dose&nbsp;of Fycompa for you.<\/li><\/ul>\n\n\n\n<p><strong>Children (from 7 to 11 years) weighing 20 kg to less than 30 kg in the treatment of generalized seizures:<\/strong><\/p>\n\n\n\n<p>The starting dose is usually 1 mg once a day before bedtime.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Your doctor may increase the&nbsp;dose&nbsp;one by 1 mg at a time up to a maintenance dose of between 4 mg and 6 mg depending on how you respond to the treatment.&nbsp;Depending on the individual treatment response and how well you tolerate the medicine, the&nbsp;dose&nbsp;can be increased to a maximum&nbsp;dose&nbsp;of 8 mg \/ day.<\/li><li>If you have mild or moderate liver problems, do not take a&nbsp;dose&nbsp;higher&nbsp;than 4 mg per day and your dose increases should be made at least two weeks apart.<\/li><li>Do not take a higher&nbsp;dose&nbsp;of Fycompa than your doctor has prescribed.&nbsp;It may take a few weeks to find the right&nbsp;dose&nbsp;of Fycompa for you.<\/li><\/ul>\n\n\n\n<p><strong>Children (from 7 to 11 years of age) weighing less than 20 kg in the treatment of generalized seizures:<\/strong><\/p>\n\n\n\n<p>The starting dose is usually 1 mg once a day before bedtime.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Your doctor may increase the&nbsp;dose&nbsp;one by 1 mg at a time up to a maintenance dose of between 2 mg and 4 mg depending on how you respond to the treatment.&nbsp;Depending on the individual treatment response and how well you tolerate the medicine, the&nbsp;dose&nbsp;can be increased to a maximum&nbsp;dose&nbsp;of 6 mg \/ day.<\/li><li>If you have mild or moderate liver problems, do not take a&nbsp;dose&nbsp;higher&nbsp;than 4 mg per day and your dose increases should be made at least two weeks apart.<\/li><li>Do not take a higher&nbsp;dose&nbsp;of Fycompa than your doctor has prescribed.&nbsp;It may take a few weeks to find the right&nbsp;dose&nbsp;of Fycompa for you.<\/li><\/ul>\n\n\n\n<p><strong>How to take Fycompa<\/strong><\/p>\n\n\n\n<p>Swallow the tablet whole with a glass of water.&nbsp;You can take Fycompa with or without food.&nbsp;The tablet should not be chewed, crushed or divided.&nbsp;The tablets cannot be divided exactly because they do not have a breaking score.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you take more Fycompa than you should<\/h2>\n\n\n\n<p>If you take more Fycompa than you should, contact your doctor immediately.&nbsp;You may become confused, anxious or aggressive.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Fycompa<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>If you forget to take a&nbsp;dose&nbsp;, wait until it is time for the next&nbsp;dose&nbsp;and then continue as usual.<\/li><li>Do not take a double&nbsp;dose&nbsp;to make up for a forgotten&nbsp;dose&nbsp;.<\/li><li>If you have missed less than seven days of treatment with Fycompa, continue to take your daily&nbsp;dose&nbsp;as prescribed by your doctor.<\/li><li>If you have missed more than seven days of treatment with Fycompa, talk to your doctor immediately.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop taking Fycompa<\/h2>\n\n\n\n<p>Take Fycompa for as long as your doctor prescribes it.&nbsp;Do not stop taking this medicine unless your doctor tells you to.&nbsp;Your doctor may reduce your&nbsp;dose&nbsp;slowly to prevent your seizures (relapses) from coming back or getting worse.<br><\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects&nbsp;, although not everybody gets them.<br><\/p>\n\n\n\n<p>Suicidal ideation and self-harm have been reported in a small number of patients treated with&nbsp;antiepileptic drugs&nbsp;.&nbsp;Contact your doctor immediately if you ever have such thoughts.<br><\/p>\n\n\n\n<p><strong>Very common&nbsp;side effect&nbsp;is<\/strong>&nbsp;(occurring in more than 1 in 10):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>dizziness<\/li><li>drowsiness (drowsiness or very great need for sleep)<\/li><\/ul>\n\n\n\n<p><strong>Common&nbsp;adverse&nbsp;s<\/strong>&nbsp;(occurring in more than 1 in 100):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>increased or decreased appetite, weight gain<\/li><li>aggression, anger, irritability, anxiety or confusion<\/li><li>difficulty walking or other balance problems (&nbsp;ataxia&nbsp;, gait disturbance, balance disorder)<\/li><li>slow speech (&nbsp;dysarthria&nbsp;)<\/li><li>blurred vision or double vision (&nbsp;diplopia&nbsp;)<\/li><li>a tingling sensation (&nbsp;vertigo&nbsp;)<\/li><li>nausea<\/li><li>back pain<\/li><li>feeling very tired<\/li><li>case<\/li><\/ul>\n\n\n\n<p><strong>Less common&nbsp;side effects&nbsp;are<\/strong>&nbsp;(may affect more than 1 in 1000 patients):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>thoughts of harming oneself or ending one&#8217;s life (suicidal thoughts), attempting to end one&#8217;s life (suicide attempt)<\/li><\/ul>\n\n\n\n<p><strong>No known frequency<\/strong>&nbsp;(cannot be calculated from the available data):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Drug&nbsp;side effect&nbsp;with&nbsp;eosinophilia&nbsp;and systemic symptoms, also called DRESS or&nbsp;hypersensitivity reaction&nbsp;during drug treatment: widespread rash, body temperature above normal, elevated level of liver enzymes, blood abnormalities (&nbsp;eosinophilia&nbsp;), enlarged&nbsp;lymph nodes&nbsp;and other organ involvement.<\/li><li>Stevens-Johnson syndrome (SJS).&nbsp;These severe skin rashes can appear reddish, &#8220;target-like&#8221; spots or circular rashes on the torso, often with blisters in the middle, missing skin and sores on the mouth, throat, nose, genitals and eyes and preceded by fever and&nbsp;flu-like symptoms&nbsp;.<\/li><\/ul>\n\n\n\n<p>Stop using perampanel if you get these symptoms and contact your doctor or seek medical attention immediately.&nbsp;See also section 2.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Fycompa<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<br><\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton and blister.&nbsp;The expiration date is the last day of the specified month.<br><\/p>\n\n\n\n<p>No special storage instructions.<br><\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<p>The active substance is perampanel.&nbsp;Each film-coated tablet contains 2 mg, 4 mg, 6 mg, 8 mg, 10 mg or 12 mg perampanel.<br><\/p>\n\n\n\n<p>Other ingredients are:<\/p>\n\n\n\n<p>Tablet core (2 mg and 4 mg tablets):<\/p>\n\n\n\n<p>Lactose monohydrate&nbsp;, low substituted hydroxypropylcellulose, povidone, magnesium stearate (E470b).<br><\/p>\n\n\n\n<p>Tablet core (6 mg, 8 mg, 10 mg and 12 mg tablets):<\/p>\n\n\n\n<p>Lactose monohydrate&nbsp;, low substituted hydroxypropylcellulose, povidone, microcrystalline cellulose, magnesium stearate (E470b).<br><\/p>\n\n\n\n<p>Film coating (2 mg, 4 mg, 6 mg, 8 mg, 10 mg and 12 mg tablets):<\/p>\n\n\n\n<p>Hypromellose 2910, talc, Macrogol 8000, titanium dioxide (E171), dyes *.<br><\/p>\n\n\n\n<p>* The dyes are:<\/p>\n\n\n\n<p>2 mg tablet: Yellow iron oxide (E172), red iron oxide (E172)<\/p>\n\n\n\n<p>4 mg tablet: Red iron oxide (E172)<\/p>\n\n\n\n<p>6 mg tablet: Red iron oxide (E172)<\/p>\n\n\n\n<p>8 mg tablet: Red iron oxide (E172), black iron oxide (E172)<\/p>\n\n\n\n<p>10 mg tablet: Yellow iron oxide (E172), FD&amp;C blue no.&nbsp;2 indigo carmine aluminum lacquer (E132)<\/p>\n\n\n\n<p>12 mg tablet: FD&amp;C blue no.&nbsp;2 indigo carmine aluminum lacquer (E132)<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and contents of the pack<\/h2>\n\n\n\n<p>All strengths of Fycompa are round, biconvex, film-coated tablets,<\/p>\n\n\n\n<p>2 mg: orange, marked with E275 on one side and \u201c2\u201d on the other.<\/p>\n\n\n\n<p>4 mg: red, marked with E277 on one side and \u201c4\u201d on the other.<\/p>\n\n\n\n<p>6 mg: pink, marked with E294 on one side and \u201c6\u201d on the other.<\/p>\n\n\n\n<p>8 mg: purple, marked with E295 on one side and \u201c8\u201d on the other.<\/p>\n\n\n\n<p>10 mg: green, marked with E296 on one side and \u201c10\u201d on the other.<\/p>\n\n\n\n<p>12 mg: blue, marked with E297 on one side and \u201c12\u201d on the other.<br><\/p>\n\n\n\n<p>Fycompa is supplied in packs of:<\/p>\n\n\n\n<p>2 mg tablet &#8211; pack of 7, 28 and 98 tablets<\/p>\n\n\n\n<p>4 mg, 6 mg, 8 mg, 10 mg, 12 mg tablets &#8211; packs of 7, 28, 84 and 98 tablets<br><\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p><strong>Marketing Authorisation Holder<\/strong><\/p>\n\n\n\n<p>Eisai GmbH<\/p>\n\n\n\n<p>Edmund-Rumpler-Stra\u00dfe 3<\/p>\n\n\n\n<p>60549 Frankfurt am Main<\/p>\n\n\n\n<p>Germany<\/p>\n\n\n\n<p>email: medinfo_de@eisai.net<br><\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Eisai GmbH<\/p>\n\n\n\n<p>Edmund-Rumpler-Stra\u00dfe 3<\/p>\n\n\n\n<p>60549 Frankfurt am Main<\/p>\n\n\n\n<p>Germany<br><\/p>\n\n\n\n<p>Contact the representative of the marketing authorization holder to find out more about this medicine:<br><\/p>\n\n\n\n<p>Eisai AB<\/p>\n\n\n\n<p>Tel: + 46 (0) 8 501 01 600<br><\/p>\n","protected":false},"excerpt":{"rendered":"<p> 2 mg, 4 mg, 6 mg, 8 mg, 10 mg and 12 mg film-coated tablets<br \/>\nperampanel<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2206,2200],"tags":[2209,2281,2212,2213,2397,2399,2400,2398,2282,2210,2211],"class_list":["post-9177","post","type-post","status-publish","format-standard","hentry","category-f","category-medicines","tag-fycompa","tag-how-to-use-fycompa","tag-medicine","tag-medicines","tag-perampanel","tag-perampanel-doses","tag-perampanel-side-effects","tag-perampanel-uses","tag-side-effects-of-fycompa","tag-tablet","tag-tablets"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/9177","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=9177"}],"version-history":[{"count":8,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/9177\/revisions"}],"predecessor-version":[{"id":9901,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/9177\/revisions\/9901"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=9177"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=9177"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=9177"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}