{"id":9114,"date":"2021-03-25T10:48:53","date_gmt":"2021-03-25T10:48:53","guid":{"rendered":"https:\/\/zeepedia.com\/?p=9114"},"modified":"2021-04-12T14:14:07","modified_gmt":"2021-04-12T14:14:07","slug":"fulvestrant-mylan","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/fulvestrant-mylan\/","title":{"rendered":"Fulvestrant Mylan &#8211; Fulvestrant uses, dose and side effects"},"content":{"rendered":"\n<p>\n\n50mg&nbsp;solution for injection&nbsp;in a pre-filled&nbsp;syringe<br>fulvestrant<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Fulvestrant Mylan is and what it is used for<\/h2>\n\n\n\n<p>Fulvestrant Mylan contains the active substance fulvestrant, which belongs to the group of estrogen blockers.&nbsp;Estrogen&nbsp;er, a type of female sex hormone, may in some cases be involved in the growth of breast cancer.<br><\/p>\n\n\n\n<p>Fulvestrant Mylan either:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>alone to treat postmenopausal women with a type of breast cancer called estrogen receptor-positive breast cancer that is locally advanced or has spread to other parts of the body (metastatic), or in combination with palbociclib for the treatment of women with a type of breast cancer called hormone receptor-positive,&nbsp;human&nbsp;epidermal&nbsp;growth&nbsp;factor&nbsp;receptor 2 \u2011 negative breast cancer, which is locally advanced or has spread to other parts of the body (metastatic).&nbsp;Women who have not reached menopause will also be treated with a drug called luteinizing hormone-releasing&nbsp;hormone&nbsp;(LHRH)&nbsp;agonist.<\/li><\/ul>\n\n\n\n<p>When fulvestrant is given in combination with palbociclib, it is important that you also read the palbociclib package leaflet.&nbsp;Ask your doctor if you have any questions about palbociclib.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before using Fulvestrant Mylan<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Fulvestrant Mylan<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to fulvestrant or any of the other ingredients of this medicine (listed in section 6)<\/li><li>if you are pregnant or breastfeeding<\/li><li>if you have severe liver problems.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor, pharmacist, or nurse before using Fulvestrant Mylan if any of the following apply to you:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>kidney or liver problems<\/li><li>low&nbsp;platelet count&nbsp;(contributes to blood clotting), bleeding disorders<\/li><li>previous problems with blood clots<\/li><li>problems with bone mineral loss (&nbsp;osteoporosis&nbsp;)<\/li><li>alcohol problem.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>Fulvestrant Mylan is not intended for use in children and adolescents below 18 years.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Fulvestrant Mylan<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.<br><\/p>\n\n\n\n<p>You must tell your doctor if you are&nbsp;taking anticoagulants&nbsp;(medicines that prevent blood clots).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>You must not use Fulvestrant Mylan if you are pregnant.&nbsp;If you could become pregnant, use an effective contraceptive when you are being treated with Fulvestrant Mylan and for 2 years after your last&nbsp;dose.<br><\/p>\n\n\n\n<p>You must not breast-feed when you are being treated with Fulvestrant Mylan<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Fulvestrant Mylan is unlikely to affect your ability to drive or use machines, but if you feel tired after treatment, avoid driving or using machines.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Fulvestrant Mylan contains excipients<\/h2>\n\n\n\n<p><strong>Fulvestrant Mylan contains 10% w \/ v&nbsp;ethanol&nbsp;(alcohol)<\/strong>, ie 500 mg per 5 ml, equivalent to 25 ml beer or 10 ml wine per treatment dose (ie two syringes).&nbsp;The small amount of alcohol in this medicine has no noticeable effects.<br><\/p>\n\n\n\n<p><strong>Fulvestrant Mylan contains benzyl alcohol<\/strong><\/p>\n\n\n\n<p>This medicine contains benzyl alcohol 500 mg per 5 ml, which is equivalent to 100 mg\/ml (10% w \/ v).&nbsp;Benzyl alcohol can cause allergic reactions.<br><\/p>\n\n\n\n<p><strong>Fulvestrant Mylan contains benzyl benzoate<\/strong><\/p>\n\n\n\n<p>This medicine contains benzyl benzoate 750 mg per 5 ml, equivalent to 150 mg \/ ml (15% w \/ v).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. How to use Fulvestrant Mylan<\/h2>\n\n\n\n<p>Always use this medicine exactly as your doctor or pharmacist has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<br><\/p>\n\n\n\n<p>The recommended&nbsp;dose&nbsp;is 500 mg fulvestrant (two 250 mg \/ 5 ml&nbsp;injections&nbsp;) once a month, with an additional&nbsp;dose&nbsp;of 500 mg two weeks after the initial&nbsp;dose.<br><\/p>\n\n\n\n<p>Your doctor or nurse will give you Fulvestrant Mylan as a slow&nbsp;intramuscular&nbsp;injection, one in each buttock.<br><\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor, pharmacist, or nurse.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects, although not everybody gets them.<br><\/p>\n\n\n\n<p><strong>You may need immediate medical attention if you get any of the following side effects:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Allergic reactions (hypersensitivity), including swelling of the face, lips, tongue, and\/or throat which may be signs of anaphylactic reactions<\/li><li>Thromboembolism (increased risk of blood clots) *<\/li><li>Inflammation of the liver (&nbsp;hepatitis&nbsp;)<\/li><li>Liver failure<\/li><\/ul>\n\n\n\n<p><strong>Tell your doctor, pharmacist, or nurse if you get any of the following side effects:<\/strong><br><\/p>\n\n\n\n<p><strong>The very common&nbsp;<\/strong>&nbsp;<strong>side effect&nbsp;is<\/strong>&nbsp;(may affect more than one in 10)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Injection site reactions, such as pain and\/or&nbsp;inflammation<\/li><li>Changes in liver enzyme values \u200b\u200b(shown by blood tests) *<\/li><li>Nausea<\/li><li>Weakness, fatigue *<\/li><li>Joint and musculoskeletal pain<\/li><li>Hemorrhoids<\/li><li>Rash<\/li><li>Allergic (hypersensitivity) reaction, including swelling of the face, lips, tongue, and\/or throat<\/li><\/ul>\n\n\n\n<p><strong>Other side effects:<\/strong><br><\/p>\n\n\n\n<p><strong>Common&nbsp;<\/strong>&nbsp;<strong>side effects&nbsp;are<\/strong>&nbsp;(may affect up to 1 in 10)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Headache<\/li><li>Vomiting, diarrhea, or decreased appetite *<\/li><li>Urinary tract infection<\/li><li>Back pain *<\/li><li>Elevation of&nbsp;bilirubin&nbsp;(a bile pigment produced by the liver)<\/li><li>Thromboembolism&nbsp;(increased risk of blood clots) *&nbsp;<\/li><li>Decreased&nbsp;platelet count&nbsp;(&nbsp;thrombocytopenia&nbsp;)<\/li><li>Vaginal&nbsp;bleeding<\/li><li>Pain in the lower back that radiates to the leg on one side (sciatica)<\/li><li>Sudden weakness, numbness, tingling, or loss of mobility in the leg, especially only on one side of the body, sudden difficulty walking or maintaining balance (&nbsp;peripheral&nbsp;neuropathy&nbsp;)<\/li><\/ul>\n\n\n\n<p><strong>Less common&nbsp;side effects&nbsp;are<\/strong>&nbsp;(may affect up to 1 in 100)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Thick, whitish&nbsp;vaginal discharge&nbsp;and fungal infection<\/li><li>Bruising and bleeding at the injection site<\/li><li>Increase in gamma \u2011 GT, a liver enzyme seen in a blood test<\/li><li>Inflammation of the liver (&nbsp;hepatitis&nbsp;)<\/li><li>Liver failure<\/li><li>Numbness, tingling, and pain<\/li><li>Anaphylactic reactions<\/li><\/ul>\n\n\n\n<p>* Includes&nbsp;side effects&nbsp;for which the exact effect of Fulvestrant Mylan cannot be assessed due to the underlying disease.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Fulvestrant Mylan<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<br><\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton and syringe label after \u201cEXP\u201d.&nbsp;The expiration date is the last day of the specified month.<br><\/p>\n\n\n\n<p>Store and transport cold (2 \u00b0 C \u2013 8 \u00b0 C).&nbsp;Deviations outside the temperature range 2 \u00b0 C-8 \u00b0 C must be limited and a period of 28 days where the average storage temperature of the product is below 25 \u00b0 C (but above 2 \u00b0 C-8 \u00b0 C) must not be exceeded.&nbsp;After temperature deviations, the product must be returned immediately to the recommended storage conditions (stored and transported cold, 2 \u00b0 C \u2013 8 \u00b0 C).&nbsp;Temperature deviations have a cumulative effect on the product quality and the time period of 28 days must not be exceeded during the entire shelf life of Fulvestrant Mylan.&nbsp;Exposure to temperatures below 2 \u00b0 C does not damage the product, provided it is not stored below -20 \u00b0 C.<br><\/p>\n\n\n\n<p>Store the prefilled syringe in the original package.&nbsp;Sensitive to light.<br><\/p>\n\n\n\n<p>The medical staff is responsible for the correct storage, use, and disposal of Fulvestrant Mylan.<br><\/p>\n\n\n\n<p>This medicine may pose a risk to the aquatic environment.&nbsp;Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is fulvestrant.&nbsp;Each pre-filled&nbsp;syringe&nbsp;(5 ml) contains 250 mg fulvestrant.<\/li><li>The other ingredients (excipients) are benzyl benzoate (see section 2 &#8220;Fulvestrant Mylan contains benzyl benzoate&#8221;), benzyl alcohol (see section 2 &#8220;Fulvestrant Mylan contains benzyl alcohol&#8221;), anhydrous&nbsp;ethanol&nbsp;(see section 2 &#8220;Fulvestrant Mylan contains 10% w \/ v&nbsp;ethanol&nbsp;(alcohol ) \u201d), And refined castor oil.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>Fulvestrant Mylan is a clear, colorless to yellow,&nbsp;viscous&nbsp;solution in a pre-filled&nbsp;syringe&nbsp;fitted with a safety closure containing 5 ml&nbsp;solution for injection.<br><\/p>\n\n\n\n<p>Fulvestrant Mylan is available in four-pack sizes, either a pack containing 1 pre-filled&nbsp;glass&nbsp;syringe&nbsp;or a pack containing 2 pre-filled glass syringes or a pack containing 4 pre-filled glass syringes or a pack containing 6 pre-filled glass syringes.&nbsp;Protected needles (BD SafetyGlide) to attach to each&nbsp;syringe&nbsp;are also included.<br><\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorisation Holder<\/h2>\n\n\n\n<p>MYLAN SAS<\/p>\n\n\n\n<p>117 All\u00e9e des Parcs<\/p>\n\n\n\n<p>69800 SAINT PRIEST FRANCE<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>MYLAN THEORY<\/p>\n\n\n\n<p>Inverin<\/p>\n\n\n\n<p>Co.&nbsp;Galway<\/p>\n\n\n\n<p>IRELAND<br><\/p>\n","protected":false},"excerpt":{"rendered":"<p> 50mg solution for injection in a pre-filled syringe<br \/>\nfulvestrant<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2206,2200],"tags":[2385,2273,2386,2384,2274,2215,2216,2212,2213,2275],"class_list":["post-9114","post","type-post","status-publish","format-standard","hentry","category-f","category-medicines","tag-fulvestrant-doses","tag-fulvestrant-mylan","tag-fulvestrant-side-effects","tag-fulvestrant-uses","tag-how-to-use-fulvestrant-mylan","tag-injection","tag-injections","tag-medicine","tag-medicines","tag-side-effects-of-fulvestrant-mylan"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/9114","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=9114"}],"version-history":[{"count":7,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/9114\/revisions"}],"predecessor-version":[{"id":9945,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/9114\/revisions\/9945"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=9114"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=9114"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=9114"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}