{"id":9048,"date":"2021-03-24T07:47:50","date_gmt":"2021-03-24T07:47:50","guid":{"rendered":"https:\/\/zeepedia.com\/?p=9048"},"modified":"2021-04-12T14:11:58","modified_gmt":"2021-04-12T14:11:58","slug":"fosrenol","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/fosrenol\/","title":{"rendered":"Fosrenol &#8211; Oral Lanthanum Powder uses, dose and side effects"},"content":{"rendered":"\n<p> 750 mg, 1,000 mg&nbsp;oral&nbsp;lanthanum&nbsp;powder<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What Fosrenol is and what it is used for<\/h2>\n\n\n\n<p>Fosrenol is used to lower the level of phosphate in the blood of adult patients with&nbsp;chronic&nbsp;kidney disease.<br><\/p>\n\n\n\n<p>In patients whose kidneys do not function normally, the kidneys cannot regulate blood phosphate levels.&nbsp;This causes the amount of&nbsp;phosphate&nbsp;in the blood to rise (doctors may call this&nbsp;hyperphosphatemia&nbsp;).<br><\/p>\n\n\n\n<p>Fosrenol is a drug that lowers the body&#8217;s uptake of&nbsp;phosphate&nbsp;from food by binding to it in the gastrointestinal tract.&nbsp;Phosphate&nbsp;bound to Fosrenol cannot be absorbed through the intestinal wall.<br><\/p>\n\n\n\n<p>The lanthanum contained in Fosrenol may also be approved for the treatment of other diseases not mentioned in this product information.&nbsp;Ask your doctor, pharmacist, or another healthcare professional if you have any further questions, and always follow their instructions.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2. What you need to know before you take Fosrenol<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not take Fosrenol<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to lanthanum carbonate hydrate or any of the other ingredients of this medicine (listed in section 6).<\/li><li>if you have too little&nbsp;phosphate&nbsp;in your blood (&nbsp;hypophosphatemia&nbsp;).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before taking Fosrenol if you know you have, have had, or have had any of the following:<br><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>cancer of the stomach or intestines<\/li><li>inflammatory&nbsp;bowel disease including&nbsp;ulcerative colitis&nbsp;or&nbsp;Crohn&#8217;s disease<\/li><li>abdominal surgery, or&nbsp;infection&nbsp;or&nbsp;inflammation&nbsp;of the abdomen\/intestine (peritonitis)<\/li><li>gastric&nbsp;or intestinal ulcers<\/li><li>intestinal blockage or slow&nbsp;motility&nbsp;(motility) in the intestine (eg constipation and stomach complications due to&nbsp;diabetes&nbsp;)<\/li><li>impaired liver or kidney function.<br><\/li><\/ul>\n\n\n\n<p>If you have impaired kidney function, your doctor may occasionally want to check the level of calcium in your blood.&nbsp;If you have too little&nbsp;calcium, you may need extra&nbsp;calcium.<br><\/p>\n\n\n\n<p>If you have to have an X-ray, tell your doctor that you are taking Fosrenol, as this may affect the results.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Fosrenol<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.<br><\/p>\n\n\n\n<p>Fosrenol may affect the way certain medicines are absorbed from the gastrointestinal tract.&nbsp;If you are taking chloroquine (for rheumatism and&nbsp;malaria&nbsp;),&nbsp;ketoconazole&nbsp;(for fungal infections),&nbsp;antibiotics&nbsp;containing&nbsp;tetracycline&nbsp;or&nbsp;doxycycline, these medicines should not be taken within 2 hours before or after taking Fosrenol.<br><\/p>\n\n\n\n<p>You should not take oral&nbsp;antibiotics&nbsp;containing floxacin (including&nbsp;ciprofloxacin&nbsp;) within 2 hours before or 4 hours after taking Fosrenol.<br><\/p>\n\n\n\n<p>If you are taking levothyroxine (due to an underactive&nbsp;thyroid gland&nbsp;) it should not be taken within 2 hours before or after taking Fosrenol.&nbsp;Your doctor may want to check your thyroid-stimulating hormone&nbsp;(&nbsp;TSH&nbsp;) levels more closely.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Fosrenol with food and drink<\/h2>\n\n\n\n<p>Fosrenol should be taken with or without food.&nbsp;Instructions on how to take Fosrenol can be found in section 3.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>Fosrenol should not be used during pregnancy.&nbsp;If you are pregnant or breast-feeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<br><\/p>\n\n\n\n<p>As it is not known if the medicine can be passed on to your baby through breast milk, you should not breast-feed while taking Fosrenol.&nbsp;If you are breast-feeding, talk to your doctor or pharmacist before taking any medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Dizziness and dizziness (a feeling of dizziness or that it &#8220;spins&#8221;) are less common&nbsp;side effects&nbsp;that have been reported by patients taking Fosrenol.&nbsp;If you experience these&nbsp;side effects, it may affect your ability to drive or use machines.<br><\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.&nbsp;One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or&nbsp;side effects.&nbsp;Descriptions of these effects and&nbsp;side effects&nbsp;can be found in other sections.&nbsp;Read all the information in this leaflet for guidance.&nbsp;If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Fosrenol contains glucose<\/h2>\n\n\n\n<p>If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to take Fosrenol<\/h2>\n\n\n\n<p>Always take this medicine exactly as your doctor or pharmacist has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<br><\/p>\n\n\n\n<p>You should take Fosrenol with or immediately after a meal.&nbsp;If you take Fosrenol before a meal, you are more likely to get&nbsp;side effects&nbsp;such as nausea and vomiting.<br><\/p>\n\n\n\n<p>Fosrenol oral powder is intended to be mixed with soft foods (eg apple puree or other similar foods) and then swallowed.&nbsp;Additional fluid is not necessary.<br><\/p>\n\n\n\n<p>Do not open the sachet until it is to be used.&nbsp;Mix all the contents of the sachet with 1 2 tablespoons of soft food and make sure that the whole&nbsp;dose is&nbsp;mixed with the food.&nbsp;Make sure you eat a&nbsp;mixture&nbsp;of oral powder and soft foods immediately (within 15 minutes).&nbsp;Never save any&nbsp;mixture&nbsp;of oral powder and food for later use.<br><\/p>\n\n\n\n<p>Your doctor will tell you how many sachets of oral powder you need to take with each meal (your daily&nbsp;dose&nbsp;will be divided between the meals).&nbsp;The number of sachets you need to take depends on:<br><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>your diet (the amount of&nbsp;phosphate&nbsp;in the food you eat)<\/li><li>the level of phosphate in your blood.<\/li><\/ul>\n\n\n\n<p>Before you start taking Fosrenol oral powder, your doctor may have used your Fosrenol&nbsp;chewable tablet&nbsp;to find the right&nbsp;dose.&nbsp;Fosrenol&nbsp;chewable&nbsp;tablets&nbsp;are available in several strengths that allow for smaller dose increases.&nbsp;The starting dose of&nbsp;chewable tablets&nbsp;is usually 250 mg three times daily with meals.&nbsp;Your&nbsp;oral powder&nbsp;dose&nbsp;is likely to be 750 or 1,000 mg three times daily with meals.&nbsp;Your doctor will check the level of phosphate in your blood at 2-3 week intervals and may increase your&nbsp;dose&nbsp;until the level of phosphate in your blood is acceptable and then regularly.<br><\/p>\n\n\n\n<p>Fosrenol works by binding&nbsp;phosphate&nbsp;from food to your gut.&nbsp;It is very important to take Fosrenol with every meal.&nbsp;If you change your diet, consult your doctor, as you may need to take extra Fosrenol.&nbsp;Your doctor will tell you what to do in this case.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you take more Fosrenol then you should<\/h2>\n\n\n\n<p>If you have ingested too much medicine or if e.g.&nbsp;If a child has inadvertently ingested the medicine, contact a doctor, hospital, or the Poison Information Center for risk assessment and advice.&nbsp;Symptoms of overdose may include nausea and headache.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Fosrenol<\/h2>\n\n\n\n<p>You must take Fosrenol with every meal.<br><\/p>\n\n\n\n<p>If you forget to take Fosrenol, take the next&nbsp;dose&nbsp;at the next meal.&nbsp;Do not take a double&nbsp;dose&nbsp;to make up for a forgotten&nbsp;dose&nbsp;.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects&nbsp;, although not everybody gets them.<br><\/p>\n\n\n\n<p><strong>Some&nbsp;side effects&nbsp;can be serious.&nbsp;Contact a doctor immediately if you get any of the following side effects:<\/strong><br><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Rupture of the intestinal wall (symptoms in the form of severe abdominal pain, chills, fever, nausea, vomiting, or tenderness in the abdomen).&nbsp;This is a rare&nbsp;side effect&nbsp;(may affect up to 1 in 1,000 people).<\/li><li>Blockage in the intestine (symptoms in the form of severe flatulence, abdominal pain, swelling or cramps, severe constipation).&nbsp;This is a less common&nbsp;side effect&nbsp;(may affect up to 1 in 100 people).<\/li><li>Contact your doctor if you experience the new-onset or worsening of constipation.&nbsp;It may be an early sign of a blockage in the gut.&nbsp;Constipation is a common&nbsp;side effect&nbsp;(may affect 1 in 10 people)&nbsp;<strong>.<\/strong><br><\/li><\/ul>\n\n\n\n<p><strong>Other minor&nbsp;side effects&nbsp;include the following:<\/strong><br><\/p>\n\n\n\n<p>Very common&nbsp;side effects&nbsp;(may affect more than 1 user in 10):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>nausea, vomiting, diarrhea, abdominal pain, headache,&nbsp;itching&nbsp;, rash.<\/li><\/ul>\n\n\n\n<p>Common&nbsp;side effects&nbsp;(may affect up to 1 in 10 users in 100):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>heartburn, flatulence<\/li><li>Hypocalcaemia&nbsp;(too little&nbsp;calcium&nbsp;in the blood) is also a common&nbsp;side effect&nbsp;.&nbsp;Symptoms of&nbsp;hypocalcaemia&nbsp;may include tingling in the hands and feet, cramps in the muscles and abdomen, or&nbsp;spasms&nbsp;in the muscles&nbsp;of the face and feet.<\/li><\/ul>\n\n\n\n<p>Uncommon&nbsp;side effects&nbsp;(may affect up to 1 in 10 users in 1,000):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>fatigue, discomfort, chest pain, weakness, swollen hands and feet, body aches, dizziness, dizziness, belching,&nbsp;inflammation&nbsp;of the stomach and intestines (&nbsp;gastroenteritis&nbsp;), indigestion, irritable bowel syndrome,&nbsp;dry mouth&nbsp;, dental disease,&nbsp;inflammation&nbsp;of the esophagus or oral cavity, loose stools, loose stools, of certain liver enzymes, parathyroid hormone, aluminum,&nbsp;calcium&nbsp;and&nbsp;glucose&nbsp;in the blood, elevated or decreased phosphate levels in the blood, thirst, weight loss, joint pain, muscle pain, weakening and decalcification of the skeleton (osteoporosis), decreased appetite, increased appetite,&nbsp;inflammation&nbsp;of the hair, increased sweating, taste changes and an increase in the number white blood cells&nbsp;.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Fosrenol<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<br><\/p>\n\n\n\n<p>No special storage instructions.<br><\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton and bag after EXP.&nbsp;The expiration date is the last day of the specified month.<br><\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Each&nbsp;sachet&nbsp;contains 750 mg of lanthanum (as lanthanum carbonate hydrate).<\/li><li>Each&nbsp;sachet&nbsp;contains 1,000 mg of lanthanum (as lanthanum carbonate hydrate).<\/li><li>The other ingredients are dextrose (hydrogenated), anhydrous&nbsp;colloidal&nbsp;silica, and magnesium stearate.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>This medicine is available as a white to off-white, oral powder in a&nbsp;sachet&nbsp;.<br><\/p>\n\n\n\n<p>The sachets are delivered in a carton with 90 sachets.&nbsp;(The outer carton contains 9 cartons with 10 sachets.)<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p><strong>Marketing Authorisation Holder<\/strong><br><\/p>\n\n\n\n<p>Shire Pharmaceuticals Ireland Limited, Block 2 &amp; 3 Miesian Plaza, 50 &#8211; 58 Baggot Street Lower,<\/p>\n\n\n\n<p>Dublin 2, Ireland<\/p>\n\n\n\n<p>Tel: +44 (0) 1256 894 959<\/p>\n\n\n\n<p>Email: medinfoEMEA@shire.com<br><\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><br><\/p>\n\n\n\n<p>Catalent Germany Schorndorf GmbH, Steinbeisstr.&nbsp;1 and 2, Schorndorf, Baden-Wuerttemberg, 73614, Germany.<br><\/p>\n\n\n\n<p>Contact the representative of the marketing authorization holder to find out more about this medicine:<br><\/p>\n\n\n\n<p>Tel: 08-731 28 00<br><\/p>\n\n\n\n<p>This medicinal product is authorized under the European Economic Area under the names:<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td>Belgium, Bulgaria, Cyprus, Denmark, Estonia, Finland, France, Greece, Iceland, Latvia, Luxembourg, the Netherlands, Norway, Poland, Portugal, Romania, Slovakia, Slovenia, Spain, the United Kingdom,  the Czech Republic, Germany, Hungary, and Austria<\/td><td>Fosrenol<\/td><\/tr><tr><td>Ireland, Italy, Malta<\/td><td>Foznol<\/td><\/tr><\/tbody><\/table><\/figure>\n","protected":false},"excerpt":{"rendered":"<p> 750 mg, 1,000 mg oral lanthanum powder<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2206,2200],"tags":[2327,2330,2212,2213,2450,2452,2449,2328,2329,2331],"class_list":["post-9048","post","type-post","status-publish","format-standard","hentry","category-f","category-medicines","tag-fosrenol","tag-how-to-use-fosrenol","tag-medicine","tag-medicines","tag-oral-lanthanum-powder-doses","tag-oral-lanthanum-powder-side-effects","tag-oral-lanthanum-powderoral-lanthanum-powder-uses","tag-powder","tag-powders","tag-side-effects-of-fosrenol"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/9048","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=9048"}],"version-history":[{"count":7,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/9048\/revisions"}],"predecessor-version":[{"id":9941,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/9048\/revisions\/9941"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=9048"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=9048"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=9048"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}