{"id":8919,"date":"2021-03-20T11:41:06","date_gmt":"2021-03-20T11:41:06","guid":{"rendered":"https:\/\/zeepedia.com\/?p=8919"},"modified":"2021-04-12T14:59:37","modified_gmt":"2021-04-12T14:59:37","slug":"fluorouracil-teva","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/fluorouracil-teva\/","title":{"rendered":"Fluorouracil Teva &#8211; Fluorouracil uses, dose and side effects"},"content":{"rendered":"\n<p>\n\n50 mg \/ ml solution for injection<br><a href=\"https:\/\/zeepedia.com\/medical\/medicines\/tolak\/\">fluorouracil<\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Fluorouracil Teva is and what it is used for<\/h2>\n\n\n\n<p>Fluorouracil Teva contains the active substance fluorouracil.&nbsp;It is a cancer drug.<br><\/p>\n\n\n\n<p>Fluorouracil Teva is used to treat many common cancers, such as colon cancer, esophageal cancer, stomach cancer, and breast cancer.<br><\/p>\n\n\n\n<p>Fluorouracil contained in Fluorouracil Teva may also be approved for the treatment of other conditions not mentioned in this product information.&nbsp;Ask your doctor, pharmacist, or other healthcare professional if you have any further questions, and always follow their instructions.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you use Fluorouracil Teva<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Fluorouracil Teva<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to fluorouracil or any of the other ingredients of this medicine (listed in section 6).<\/li><li>if you have a serious&nbsp;infection&nbsp;(eg&nbsp;shingles, chickenpox).<\/li><li>if you are severely debilitated by long-term illness.<\/li><li>if your&nbsp;bone marrow&nbsp;has been damaged by other treatments (including radiation therapy).<\/li><li>if your&nbsp;tumor is&nbsp;not&nbsp;malignant.<\/li><li>if you have severe hepatic impairment.<\/li><li>if you are being treated with, or within the last 4 weeks have been treated with brivudine to treat&nbsp;herpes&nbsp;zoster (chickenpox or&nbsp;shingles&nbsp;).<\/li><li>if you have identical pairs of genes for the&nbsp;enzyme&nbsp;DPD (dihydropyrimide dehydrogenase).<\/li><li>if you know you are completely devoid of the activity of the&nbsp;enzyme&nbsp;dihydropyrimide dehydrogenase (DPD).<\/li><li>if you are pregnant or breastfeeding.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor or nurse before using Fluorouracil Teva.<br><\/p>\n\n\n\n<p>Take special care with Fluorouracil Teva:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have too low several&nbsp;white blood cells&nbsp;and&nbsp;platelets&nbsp;(you will have to take blood samples to check this).<\/li><li>if you have a sore mouth, fever, or any bleeding or if you are weakened (these symptoms may be due to your blood containing a very low number of&nbsp;blood cells&nbsp;).<\/li><li>if you have kidney problems.<\/li><li>if you have liver problems.<\/li><li>if you have heart problems.&nbsp;Tell your doctor if you feel chest pain during treatment.<\/li><li>if you know that the&nbsp;enzyme&nbsp;dihydropyrimide dehydrogenase (DPD) is partially inactive in you.&nbsp;<\/li><li>if the&nbsp;enzyme&nbsp;a dihydropyrimide dehydrogenase (DPD) is partially or completely inactive in someone in your family<\/li><li>if you have received high doses of radiation in the pelvic area.<\/li><li>if you have gastrointestinal side effects (diarrhea, gastrointestinal bleeding),&nbsp;inflammation&nbsp;of the oral mucosa, or bleeding elsewhere.<\/li><li>if you experience nerve damage such as lack of coordination of muscle movements or tremors.<\/li><li>if you are of&nbsp;childbearing&nbsp;age.&nbsp;Women and men of&nbsp;childbearing potential&nbsp;must use effective contraception during treatment and 6 months afterward.&nbsp;See also section &#8220;Pregnancy, breast-feeding and fertility&#8221;.<\/li><\/ul>\n\n\n\n<p>DPD Deficiency: DPD deficiency is a congenital condition that is not usually associated with health problems unless you use certain medications.&nbsp;If you have DPD deficiency and are taking Fluorouracil Teva, you have an increased risk of serious&nbsp;side effects&nbsp;(listed in section 4 Possible&nbsp;side effects&nbsp;).&nbsp;It is recommended that you be tested for DPD deficiency before starting treatment.&nbsp;If you have no&nbsp;enzyme&nbsp;activity, do not take Fluorouracil Teva.&nbsp;If you have reduced enzyme activity (&nbsp;partial&nbsp;deficiency), your doctor may&nbsp;prescribe&nbsp;a lower&nbsp;dose.&nbsp;Serious and life-threatening&nbsp;side effects&nbsp;can still occur even if your test result for DPD deficiency is negative.&nbsp;<br><\/p>\n\n\n\n<p>Contact healthcare professionals immediately if you experience the following signs or symptoms: new onset of confusion, disorientation or otherwise altered mental status, problems with balance or coordination, visual disturbances.&nbsp;These can be signs of brain disease that can lead to&nbsp;coma&nbsp;and death if&nbsp;left&nbsp;untreated.<br><\/p>\n\n\n\n<p>Avoid prolonged exposure to sunlight when treated with this medicine as fluorouracil may increase sensitivity to sunlight.&nbsp;Radiation just before or after treatment with fluorouracil can cause increased&nbsp;pigmentation&nbsp;on skin areas exposed to sunlight.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Fluorouracil Teva<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.&nbsp;This is very important, as taking more than one medicine at the same time may intensify or weaken the effect of the medicines. <a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=19910920000029#\" rel=\"noopener\">Show larger<\/a><\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong>You must not take brivudine (antiviral medicine used to treat&nbsp;shingles&nbsp;or chickenpox) while you are being treated with fluorouracil (including during the rest period when you are not using fluorouracil).&nbsp;If you have taken brivudine, you must wait at least 4 weeks after stopping brivudine before starting fluorouracil treatment.&nbsp;See also section \u201cDo not use Fluorouracil Teva\u201d.<\/strong><\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p>The effect of Fluorouracil Teva may be affected by certain medicines containing the following active substances:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>cyclophosphamide (an anticancer medicine)<\/li><li>vincristine (a medicine used to treat cancer)<\/li><li>methotrexate, (an anticancer medicine)<\/li><li>cisplatin (an anticancer medicine)<\/li><li>doxorubicin (an anticancer medicine)<\/li><li>metronidazole (an&nbsp;antibiotic&nbsp;)<\/li><li>calcium leucovorin (also called calcium folinate &#8211; used to reduce the harmful effects of anti-cancer drugs)<\/li><li>interferon&nbsp;alfaallopurinol (used to treat&nbsp;gout&nbsp;)<\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/medicines\/triobe\/\">folic acid<\/a><\/li><li>cimetidine (used to treat&nbsp;stomach ulcers&nbsp;)<\/li><\/ul>\n\n\n\n<p>Fluorouracil Teva may affect the effectiveness of certain medicines containing the following active substances:<br><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>phenytoin&nbsp;(used to treat epilepsy\/seizures) as combined treatment with fluorouracil may increase the levels of&nbsp;phenytoin&nbsp;in the blood.<\/li><li>warfarin&nbsp;(used to counteract blood clots).&nbsp;Combination with fluorouracil may affect the breakdown of&nbsp;warfarin&nbsp;so that the warfarin dose needs to be lowered.<br><\/li><\/ul>\n\n\n\n<p>Other medicines in combination with Fluorouracil Teva<br><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>levamisole (used to treat machine infection), in combination with Fluorouracil Teva, may cause liver damage.<\/li><li>clozapine (an antipsychotic drug) in combination with Fluorouracil Teva should be avoided due to the increased risk of the severe reduction in&nbsp;granulocytes, a type of&nbsp;white blood cell vinorelbine (a medicine used to treat cancer) in combination with Fluorouracil Teva and folic acid can cause painful damage and&nbsp;inflammation&nbsp;of the oral mucosa.<\/li><li>tamoxifen (a medicine used to treat cancer) in combination with cyclophosphamide, methotrexate, and Fluorouracil Teva may increase the risk of blood clots.<\/li><li>Thiazide diuretics (diuretics, antihypertensive drugs) in addition to a combination of cyclophosphamide, methotrexate, and Fluorouracil Teva may result in a decrease in the number of&nbsp;granulocytes&nbsp;(a type of&nbsp;white blood cell&nbsp;).<\/li><li>Mitomycin (cytotoxic&nbsp;antibiotic&nbsp;) in combination with Fluorouracil Teva may reduce&nbsp;red blood cell counts&nbsp;and&nbsp;acute&nbsp;renal failure.<br><\/li><\/ul>\n\n\n\n<p>People treated with Fluorouracil Teva are at risk of developing a weakened immune system.&nbsp;Vaccination with live vaccines should therefore be avoided.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n<p>If you are pregnant or breast-feeding, think you may be pregnant, or are planning to have a baby, ask your doctor for advice before using this medicine.<br><\/p>\n\n\n\n<p><em>Pregnancy<\/em><\/p>\n\n\n\n<p>You must not use this medicine if you are pregnant or planning to become pregnant.<\/p>\n\n\n\n<p>If you are a woman of&nbsp;childbearing potential, you must use an effective method of contraception while you are taking this medicine and for at least 6 months afterward.&nbsp;If you become pregnant during treatment, tell your doctor.<br><\/p>\n\n\n\n<p><em>Breast-feeding<\/em><\/p>\n\n\n\n<p>Do not breast-feed while you are being treated with Fluorouracil Teva.&nbsp;The medicine can be passed on to the baby via breast milk.<br><\/p>\n\n\n\n<p><em>Fertility<\/em><\/p>\n\n\n\n<p>If you are a man, you should avoid becoming the father of a child during treatment and for 6 months afterward.&nbsp;You are advised to apply for sperm preservation before treatment as there is a risk that treatment with Fluorouracil Teva will cause persistent&nbsp;infertility.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Fluorouracil Teva can cause&nbsp;side effects&nbsp;such as nausea and vomiting.&nbsp;It can also have unwanted effects on the nervous system and vision changes.&nbsp;You should not drive or use machines if you have these symptoms.<br><\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.&nbsp;One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or&nbsp;side effects.&nbsp;Descriptions of these effects and&nbsp;side effects&nbsp;can be found in other sections.&nbsp;Read all the information in this leaflet for guidance.&nbsp;If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Fluorouracil Teva contains sodium<\/h2>\n\n\n\n<p>This medicine contains 41 mg&nbsp;sodium&nbsp;(the main ingredient in common table salt) per 5 ml vial, 82 mg&nbsp;sodium&nbsp;per 10 ml vial, 164 mg&nbsp;sodium&nbsp;per 20 ml vial, and 821 mg&nbsp;sodium&nbsp;per 100 ml vial.&nbsp;This corresponds to 2%, 4%, 8%, and 41% respectively of the daily recommended maximum intake of&nbsp;sodium&nbsp;for an adult.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. How to use Fluorouracil Teva<\/h2>\n\n\n\n<p>The dose of medicine you receive depends on your medical condition, your body weight, whether you have recently had surgery, and how well your liver and kidneys are functioning.&nbsp;It also depends on your blood test results.&nbsp;Your first course of treatment may consist of one&nbsp;dose a&nbsp;week or daily for 3-5 consecutive days.<br><\/p>\n\n\n\n<p>The medicine can be diluted with a glucose solution, sodium chloride solution, or water for injections before you get it.&nbsp;You usually receive the medicine in a vein, either as a regular&nbsp;injection&nbsp;or as a slow drip (&nbsp;infusion&nbsp;).<br><\/p>\n\n\n\n<p>Additional treatment regimens may be given depending on how you respond to the treatment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you take more Fluorouracil Teva then you should<\/h2>\n\n\n\n<p>This medicine is given to you under medical supervision, so it is unlikely that you will get too little or too much.&nbsp;If you still have questions, or if, for example, a child has ingested the medicine by mistake, contact a doctor, hospital, or the Poison Information Center for risk assessment and advice.<br><\/p>\n\n\n\n<p>Blood samples will be taken during and after treatment with Fluorouracil Teva to check the number of&nbsp;white blood cells.&nbsp;Treatment may need to be stopped if the number of&nbsp;white blood cells&nbsp;becomes too low.<br><\/p>\n\n\n\n<p>The following symptoms may occur in patients who have received too much fluorouracil: Nausea, vomiting, diarrhea, severe&nbsp;mucositis&nbsp;(ulcers in the oral mucosa), and ulcers or bleeding in the gastrointestinal tract.&nbsp;If you have any further questions on the use of this product, ask your doctor.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects, although not everybody gets them.<br><\/p>\n\n\n\n<p><strong>If any of the following occur, tell your doctor or healthcare provider immediately:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>severe&nbsp;allergic reaction&nbsp;&#8211; you may suddenly have an itchy rash (&nbsp;hives&nbsp;), swelling of your hands, feet, ankles, face, lips, mouth, or throat (which may make it difficult to swallow or breathe) and you may feel dizzy<\/li><li>chest pain<\/li><li>respiratory distress<\/li><li>your stool is bloodstained or black<\/li><li>you get a sore mouth or a sore mouth<\/li><li>numbness, tingling, or trembling in the hands or feet<\/li><li>heart rate&nbsp;increases and you feel short of breath<\/li><li>you feel confused or unsteady on your feet, have problems with coordination in arms and legs, difficulty thinking \/ speaking, problems with vision\/memory<\/li><li>If&nbsp;severe&nbsp;stomatitis&nbsp;(sores in your mouth and\/or throat), mucositis, diarrhea,&nbsp;neutropenia&nbsp;(increased risk of&nbsp;infections&nbsp;), or neurotoxicity occurs during the first treatment cycle, this may be due to DPD deficiency (see section 2 Warnings and precautions).<\/li><\/ul>\n\n\n\n<p>These are serious&nbsp;side effects.&nbsp;You may need&nbsp;urgent&nbsp;medical attention.<br><\/p>\n\n\n\n<p><strong>Very common (may affect more than 1 user in 10):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>neutropenia&nbsp;(abnormally low neutrophil&nbsp;leukocyte&nbsp;s, a type of&nbsp;white blood cells&nbsp;in the blood)<\/li><li>leukopenia&nbsp;(abnormally low&nbsp;white blood cell count,&nbsp;leukocytes, in the blood)<\/li><li>thrombocytopenia&nbsp;(abnormally low number of&nbsp;platelets,&nbsp;platelets, blood)<\/li><li>agranulocytosis&nbsp;(abnormally low number of&nbsp;granulocytes, a type of&nbsp;white blood cell&nbsp;)<\/li><li>anemia&nbsp;(decreased number of&nbsp;red blood cells&nbsp;which can lead to fatigue and lack of energy)<\/li><li>pancytopenia (drastic reduction or cessation of bone marrow blood cell production)<\/li><li>bronchospasm&nbsp;(spasm of the trachea)<\/li><li>weakened immune system with increased risk of&nbsp;infection<\/li><li>hyperuricemia (increased level of&nbsp;uric acid&nbsp;in the blood)<\/li><li>heart problems (&nbsp;ECG&nbsp;changes)<\/li><li>mucositis (oral inflammation, esophagitis, pharyngitis,&nbsp;inflammation&nbsp;of the rectum or rectum)<\/li><li>loss of appetite<\/li><li>vomiting<\/li><li>diarrhea<\/li><li>nausea<\/li><li>hair loss<\/li><li>hand-foot syndrome (a harmful skin reaction that can cause&nbsp;redness, tenderness, and possible scaling of the palms and soles of the feet)<\/li><li>delayed wound healing<\/li><li>nosebleeds<\/li><li>fatigue<\/li><li>general weakness<\/li><li>infection&nbsp;is<\/li><li>fatigue<\/li><li>lack of energy<br><\/li><\/ul>\n\n\n\n<p><strong>Common (may affect up to 1 in 10 people):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>angina pectoris<\/li><li>skin changes, eg dry skin, cracks, flaky skin (scaling),&nbsp;redness, itchy maculopapular rash (a rash that begins on the legs and continues to the arms and then to the chest) skin rash,&nbsp;hives, photosensitivity, dark spots on the skin (&nbsp;hyperpigmentation&nbsp;), dark streaks on the skin (streaked&nbsp;hyperpigmentation&nbsp;) or light skin&nbsp;areas&nbsp;(&nbsp;depigmentation&nbsp;) near veins<\/li><li>cerebral&nbsp;ataxia&nbsp;(lack of movement coordination due to damage or disease of the cerebellum)<\/li><li>redness&nbsp;and&nbsp;hyperpigmentation&nbsp;(dark spots on the skin) along the vein used for&nbsp;injection&nbsp;a<\/li><li>low&nbsp;white blood cell count&nbsp;with fever<\/li><\/ul>\n\n\n\n<p><strong>Uncommon (may affect up to 1 in 100 people):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>abnormal heart rhythm<\/li><li>heart attack<\/li><li>cardiac ischemia (decreased oxygen supply to the heart muscle)<\/li><li>myocarditis&nbsp;(&nbsp;inflammation&nbsp;of the heart muscle)<\/li><li>heart failure<\/li><li>dilated&nbsp;cardiomyopathy&nbsp;(a heart disease in which the heart muscle is abnormally enlarged, thickened, and\/or frozen)<\/li><li>the shock&nbsp;caused by severe&nbsp;heart failure<\/li><li>low&nbsp;blood pressure<\/li><li>dehydration<\/li><li>bacterial&nbsp;infection&nbsp;in blood circulation or body tissue<\/li><li>ulcers or bleeding in the gastrointestinal tract, flaking of the skin<\/li><li>damage to liver cells<\/li><li>disturbed sperm or egg production<\/li><li>nail changes (eg blue&nbsp;pigmentation&nbsp;near the surface,&nbsp;hyperpigmentation, deformed nails) pain and thickening of the&nbsp;nail bed&nbsp;a<\/li><li>involuntary twitching eye movements<\/li><li>headache<\/li><li>the feeling of imbalance and instability<\/li><li>symptoms similar to those of&nbsp;Parkinson&#8217;s disease&nbsp;(a movement disorder characterized by tremors, stiffness, and slow movements)<\/li><li>pyramidal symptoms (such as loss of fine motor skills and reflex disorders)<\/li><li>feeling of well-being<\/li><li>somnolence<\/li><li>increased tear flow<\/li><li>dimsyn<\/li><li>disturbance in the eye movements<\/li><li>optic&nbsp;neuritis&nbsp;(visual disturbance caused by&nbsp;inflammation&nbsp;of the&nbsp;optic nerve&nbsp;)<\/li><li>double vision<\/li><li>decreased&nbsp;visual acuity<\/li><li>extreme light sensitivity and avoidance of sunlight and brightly lit places<\/li><li>conjunctivitis&nbsp;(&nbsp;inflammation&nbsp;or&nbsp;redness&nbsp;of the membrane (conjunctiva) that covers the white of the eye and the back of the eyelid)<\/li><li>eye disease with&nbsp;chronic&nbsp;inflammation&nbsp;of the eyelid rim<\/li><li>the lower eyelid is facing outwards<\/li><li>blocked tear ducts<br><\/li><\/ul>\n\n\n\n<p><strong>Rare (may affect up to 1 in 1,000 people):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>general&nbsp;allergic reaction<\/li><li>severe&nbsp;allergic reaction&nbsp;involving the whole body (&nbsp;anaphylaxis&nbsp;)<\/li><li>dilation of blood vessels throughout the body resulting in a drop in blood pressure<\/li><li>increase in thyroid hormones T4 (&nbsp;thyroxine&nbsp;) and&nbsp;T3&nbsp;(triiodothyronine)<\/li><li>insufficient blood supply to the brain, intestines, and peripheral organs<\/li><li>discoloration of fingers and toes and in some cases also other parts of the body, due to&nbsp;decreased blood flow<\/li><li>the occurrence of a blood clot in&nbsp;artery&nbsp;or vein<\/li><li>swelling (&nbsp;inflammation&nbsp;) in a vein<\/li><li>disorientation, mental confusion, or impaired consciousness, in particular about time, space, and identity<br><\/li><\/ul>\n\n\n\n<p><strong>Very rare (may affect up to 1 in 10,000 people):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>sudden cardiac death (unexpected death due to heart problem)<\/li><li>damage to liver cells (in rare cases with fatal outcome)<\/li><li>slow increasing degradation of the small bile ducts<\/li><li>inflammation&nbsp;of the gallbladder<\/li><li>symptoms such as leukoencephalopathy (a disease affecting the white matter of the brain) with loss of muscle coordination ability<\/li><li>acute&nbsp;cerebellar syndrome (difficulty coordinating muscle movements)<\/li><li>difficulty articulating words<\/li><li>abnormal muscle weakness or muscle fatigue<\/li><li>partial or total loss of the ability to communicate verbally or use written language<\/li><li>seizures or&nbsp;coma&nbsp;in patients receiving high-&nbsp;dose&nbsp;fluorouracil and in patients with a deficiency of the&nbsp;enzyme&nbsp;dihydropyrimide dehydrogenase (DPD)<\/li><li>kidney failure<\/li><li>cardiac arrest<\/li><\/ul>\n\n\n\n<p><strong>Has been reported (occurs in an unknown number of users):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>fever<\/li><li>numbness or weakness in the arms and legs may occur<\/li><li>hyperammonemia&nbsp;encephalopathy&nbsp;(impaired function in the brain due to increased levels of ammonia)<\/li><\/ul>\n\n\n\n<p>Numbness or weakness in the arms and legs may occur<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Fluorouracil Teva<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<br><\/p>\n\n\n\n<p>Do not store above 25 \u00b0 C.&nbsp;Store in the original package.&nbsp;Sensitive to light.<br><\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the label and carton after EXP.&nbsp;The expiration date is the last day of the specified month.<br><\/p>\n\n\n\n<p>Completed solutions should be used within 12 hours.<br><\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is fluorouracil.&nbsp;1 ml&nbsp;solution for injection&nbsp;contains 5 \u2011 fluorouracil 50 mg.<\/li><li>The other ingredients are sodium hydroxide and water for injections.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>Vials: 5 ml, 10 ml, 20 ml, and 100 ml.<\/p>\n\n\n\n<p>Ampoules: 5 ml and 10 ml<\/p>\n\n\n\n<p>Infusion bottles: 100 ml<br><\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p>Teva AB<\/p>\n\n\n\n<p>Box 1070<\/p>\n\n\n\n<p>251 10 Helsingborg<br><\/p>\n","protected":false},"excerpt":{"rendered":"<p> 50 mg \/ ml solution for injection<br \/>\nfluorouracil<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2206,2200],"tags":[2639,2641,2642,2643,2645,2646,2644,2640,2215,2212],"class_list":["post-8919","post","type-post","status-publish","format-standard","hentry","category-f","category-medicines","tag-fluorouracil","tag-fluorouracil-dose","tag-fluorouracil-side-effects","tag-fluorouracil-teva","tag-fluorouracil-teva-dose","tag-fluorouracil-teva-side-effects","tag-fluorouracil-teva-uses","tag-fluorouracil-uses","tag-injection","tag-medicine"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8919","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=8919"}],"version-history":[{"count":6,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8919\/revisions"}],"predecessor-version":[{"id":9997,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8919\/revisions\/9997"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=8919"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=8919"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=8919"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}