{"id":8905,"date":"2021-03-20T11:27:57","date_gmt":"2021-03-20T11:27:57","guid":{"rendered":"https:\/\/zeepedia.com\/?p=8905"},"modified":"2021-04-12T15:10:52","modified_gmt":"2021-04-12T15:10:52","slug":"fluenz-tetra","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/fluenz-tetra\/","title":{"rendered":"Fluenz Tetra &#8211; Nasal Spray uses, dose and side effects"},"content":{"rendered":"\n<p> nasal spray suspension<br>A vaccine against&nbsp;influenza&nbsp;(live attenuated, nasal)<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What Fluenz Tetra is and what it is used for<\/h2>\n\n\n\n<p>Fluenz Tetra is a vaccine that prevents&nbsp;flu.&nbsp;It is used for children and adolescents aged from 24 months up to 18 years.&nbsp;Fluenz Tetra protects against the four virus strains contained in the vaccine and other strains that are closely related to them.<br><\/p>\n\n\n\n<p><strong>How Fluenz Tetra works<\/strong><br><\/p>\n\n\n\n<p>When a person receives the vaccine, the immune system (the body&#8217;s natural defense system) will produce its own protection against the flu virus.&nbsp;None of the ingredients in the vaccine can cause the&nbsp;flu.<br><\/p>\n\n\n\n<p>The Fluenz Tetra vaccine virus is grown in chicken eggs.&nbsp;The vaccine is targeted at four influenza virus strains per year, according to annual recommendations from the World Health Organization.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2. What you need to know before you get Fluenz Tetra<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">You will not receive Fluenz Tetra:<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>if you are allergic<\/strong>&nbsp;to eggs, egg proteins, gentamicin or gelatin, or any of the other ingredients of this vaccine (listed in section 6 \u201cPackage contents and other information\u201d).<\/li><li>if you have ever had a severe&nbsp;allergic reaction&nbsp;to eggs or egg proteins.&nbsp;For signs of allergic reactions, see section 4 &#8220;Possible side effects&#8221;.<\/li><li>if you have a&nbsp;<strong>blood disease<\/strong>&nbsp;or <strong>cancer<\/strong>&nbsp;that&nbsp;<strong>affects the immune system<\/strong>.<\/li><li>if&nbsp;<strong>your doctor has informed you<\/strong>&nbsp;that you have&nbsp;<strong>a weakened immune system<\/strong>&nbsp;due to an illness, a drug, or any other treatment.<\/li><li><strong>if you are already taking&nbsp;<em><a href=\"https:\/\/zeepedia.com\/medical\/medicines\/tiplo-citrus\/\">acetylsalicylic acid<\/a><\/em>&nbsp;<\/strong>(a substance found in many painkillers and antipyretics).&nbsp;This is due to the risk of a very unusual but serious disease&nbsp;<em>(Reyes syndrome).<\/em><\/li><\/ul>\n\n\n\n<p>If any of the above apply to you,&nbsp;<strong>tell<\/strong>&nbsp;your&nbsp;<strong>doctor, nurse, or pharmacist.<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p><strong>Talk to a doctor, nurse, or pharmacist before vaccination:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if the&nbsp;<strong>baby is under 24 months old.&nbsp;<\/strong>Children under 24 months of age should not be given this vaccine due to the risk of&nbsp;side effects.<\/li><li>if you have&nbsp;<strong>severe&nbsp;asthma&nbsp;<\/strong>or are currently wheezing.<\/li><li>if you have&nbsp;<strong>close contact with someone who has a severely weakened immune system<\/strong>&nbsp;(for example, a bone marrow transplant patient who needs to be isolated).<\/li><\/ul>\n\n\n\n<p>If any of the above apply to you,&nbsp;<strong>talk to your doctor, nurse, or pharmacist before getting vaccinated.&nbsp;<\/strong>He or she will decide if Fluenz Tetra is right for you.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines, other vaccines, and Fluenz Tetra<\/h2>\n\n\n\n<p>Tell your doctor, nurse, or pharmacist if the person being vaccinated is taking, has recently taken, or might be taking other medicines, including over-the-counter medicines.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Do not give&nbsp;<em>acetylsalicylic acid<\/em><\/strong>&nbsp;(a substance that is included in many medicines with analgesic and antipyretic effects)&nbsp;<strong>to children<\/strong>&nbsp;under 4 weeks after vaccination with Fluenz Tetra, unless your doctor, nurse, or pharmacist tells you otherwise.&nbsp;It is due to the risk of Reye&#8217;s syndrome, a very rare but serious disease that can affect the brain and liver.<\/li><li><strong>It is not recommended that Fluenz Tetra be<\/strong>&nbsp;co-administered&nbsp;with influenza-specific<strong> antiviral medicines<\/strong>, such as&nbsp;<em>oseltamivir<\/em>&nbsp;and&nbsp;<em>zanamivir<\/em>.&nbsp;This is because the vaccine may be less effective.<\/li><\/ul>\n\n\n\n<p>Your doctor, nurse, or pharmacist will decide if Fluenz Tetra can be given at the same time as other vaccines.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>If you are&nbsp;<strong>pregnant,<\/strong>&nbsp;think you may be pregnant, are planning to become pregnant, or are breast-feeding<strong>, tell your doctor, nurse, or pharmacist before receiving this vaccine.&nbsp;<\/strong>Fluenz Tetra&nbsp;<strong>is not recommended<\/strong>&nbsp;for pregnant or lactating women.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Fluenz Tetra has no or negligible effect on the ability to drive and use machines.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">3. How Fluenz Tetra is given<\/h2>\n\n\n\n<p><strong>Fluenz Tetra is administered under the supervision of a doctor, nurse, or pharmacist.<\/strong><\/p>\n\n\n\n<p>Fluenz Tetra should only be used as a nasal spray.<br><\/p>\n\n\n\n<p><strong>Fluenz Tetra must not be injected.<\/strong><br><\/p>\n\n\n\n<p>Fluenz Tetra will be given as a spray in each nostril.&nbsp;You can breathe normally while receiving Fluenz Tetra.&nbsp;You do not need to inhale actively or inhale air through your nose.<br><\/p>\n\n\n\n<p><strong>Dosage<\/strong><\/p>\n\n\n\n<p><strong>The recommended&nbsp;dose of&nbsp;<\/strong>children and adolescents is 0.2 ml Fluenz Tetra, where 0.1 ml given into each nostril.&nbsp;<strong>Children who have not previously received a flu vaccine<\/strong>&nbsp;will receive a second follow-up dose after an interval of at least 4 weeks.&nbsp;Follow the instructions of your doctor, nurse, or pharmacist regarding if and when your child should return for the second&nbsp;dose.<br><\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor, nurse, or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this vaccine can cause&nbsp;side effects, although not everybody gets them.&nbsp;In&nbsp;clinical trials&nbsp;with the vaccine, most&nbsp;side effects were&nbsp;mild and short-lived.<br><\/p>\n\n\n\n<p>Your doctor, nurse, or pharmacist can give you more information about any&nbsp;side effects&nbsp;of Fluenz Tetra.<br><\/p>\n\n\n\n<p><strong>Some&nbsp;side effects&nbsp;can be serious<\/strong><br><\/p>\n\n\n\n<p><strong>Very rare<\/strong><\/p>\n\n\n\n<p><em>(may affect up to 1 user in 10,000)<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Severe allergic reaction: Signs of a severe&nbsp;allergic reaction&nbsp;may include shortness of breath and swelling of the face or tongue.<\/li><\/ul>\n\n\n\n<p><strong>Tell<\/strong>&nbsp;your&nbsp;<strong>doctor immediately or seek emergency medical attention<\/strong>&nbsp;if you experience any of the&nbsp;above&nbsp;side effects.<br><\/p>\n\n\n\n<p><strong>Other possible&nbsp;side effects&nbsp;are Fluenz Tetra<\/strong><br><\/p>\n\n\n\n<p><strong>Very common<\/strong><\/p>\n\n\n\n<p><em>(may affect more than 1 user in 10):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>runny or stuffy nose<\/li><li>decreased appetite<\/li><li>weakness<\/li><\/ul>\n\n\n\n<p><strong>Usual<\/strong><\/p>\n\n\n\n<p><em>(may affect up to 1 user in 10):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>fever<\/li><li>muscle aches<\/li><li>headache<\/li><\/ul>\n\n\n\n<p><strong>Less common<\/strong><\/p>\n\n\n\n<p><em>(may affect up to 1 user in 100):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>rash<\/li><li>nosebleeds<\/li><li>allergic reactions<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Fluenz Tetra<\/h2>\n\n\n\n<p>Keep this vaccine out of the reach and sight of children.<br><\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the pipette label after the letters EXP.<br><\/p>\n\n\n\n<p>Store in a refrigerator (2 \u00b0 C-8 \u00b0 C).&nbsp;Do not freeze.<br><\/p>\n\n\n\n<p>Sensitive to light.&nbsp;Store the nasal pipette in the outer carton.<br><\/p>\n\n\n\n<p>Before use, the vaccine may be removed from the refrigerator for a maximum period of 12 hours at a temperature not exceeding 25 \u00b0 C.&nbsp;If the vaccine has not been used after this 12-hour period, it should be discarded.<br><\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<p>The active substances are:<\/p>\n\n\n\n<p>Reassortant influenza virus * (live, attenuated) of the following four strains **:<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td>A \/ Guangdong-Maonan \/ SWL1536 \/ 2019 (H1N1) pdm09 &#8211; similar strain(A \/ Hawaii \/ 66\/2019, MEDI 326775)<\/td><td>10&nbsp;<sup>7.0 \u00b1 0.5<\/sup>&nbsp;FFU ***<\/td><\/tr><tr><td>A \/ Hong Kong \/ 2671\/2019 (H3N2) &#8211; similar strain<br>(A \/ Hong Kong \/ 2671\/2019, MEDI 325078)<\/td><td>10&nbsp;<sup>7.0 \u00b1 0.5<\/sup>&nbsp;FFU ***<\/td><\/tr><tr><td>B \/ Washington \/ 02\/2019 &#8211; similar strain(B \/ Washington \/ 02\/2019, MEDI 323797)<\/td><td>10&nbsp;<sup>7.0 \u00b1 0.5<\/sup>&nbsp;FFU ***<\/td><\/tr><tr><td>B \/ Phuket \/ 3073\/2013 &#8211; similar strain(B \/ Phuket \/ 3073\/2013, MEDI 306444)<\/td><td>10&nbsp;<sup>7.0 \u00b1 0.5<\/sup>&nbsp;FFU ***<\/td><\/tr><tr><td>&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.. &#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;&#8230;.<\/td><td>per 0.2 ml&nbsp;dose<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p>* propagated in fertilized chicken eggs from healthy chicken herds.<\/p>\n\n\n\n<p>** produced in VERO cells by reverse genetic engineering.&nbsp;This product contains genetically modified&nbsp;organisms&nbsp;(GMOs).<\/p>\n\n\n\n<p>*** fluorescent focus units.<br><\/p>\n\n\n\n<p>This vaccine complies with the recommendation of the WHO (World Health Organization) (Northern Hemisphere) and the EU decision for the 2020\/2021 season.<br><\/p>\n\n\n\n<p>The other ingredients are sucrose, dipotassium phosphate, potassium dihydrogen phosphate, gelatin (porcine, type A), arginine hydrochloride, monosodium \u2011 glutamate monohydrate, and water for&nbsp;injections.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>This vaccine is supplied as a nasal spray,&nbsp;suspension, in a single-use nasal pipette (0.2 ml) in pack sizes of 1 or 10. Not all pack sizes may be available in your country.<br><\/p>\n\n\n\n<p>Manufacturer:<\/p>\n\n\n\n<p>MedImmune Pharma BV,<\/p>\n\n\n\n<p>Lagelandseweg 78<\/p>\n\n\n\n<p>Nijmegen, 6545CG<\/p>\n\n\n\n<p>Netherlands<br><\/p>\n\n\n\n<p>MedImmune, UK Limited,<\/p>\n\n\n\n<p>Plot 6, Renaissance Way,<\/p>\n\n\n\n<p>Boulevard Industry Park,<\/p>\n\n\n\n<p>Speke,<\/p>\n\n\n\n<p>Liverpool, L24 9JW,<\/p>\n\n\n\n<p>UK<br><\/p>\n\n\n\n<p>Contact the representative of the marketing authorization holder to find out more about this medicine:<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong>Belgium \/ Belgique \/ Belgien<\/strong>NV AstraZeneca SATel: +32 2 370 48 11<\/td><td><strong>Lithuania<\/strong>UAB, AstraZeneca LietuvaTel: +370 5 2660550<\/td><\/tr><tr><td><strong>Bulgaria<\/strong>\u0422\u041f AstraZeneca UK LimitedTel .: +359 2 971 25 33<\/td><td><strong>Luxembourg \/ Luxemburg<\/strong>NV AstraZeneca SATel: +32 2 370 48 11<\/td><\/tr><tr><td><strong>Czech Republic<\/strong>AstraZeneca Czech Republic sroTel: +420222807111<\/td><td><strong>Hungary<\/strong>AstraZeneca KftTel .: +36 1 883 6500<\/td><\/tr><tr><td><strong>Denmark<\/strong>AstraZeneca A \/ STel: +45 43 66 64 62<\/td><td><strong>Malta<\/strong>Associated Drug Co.&nbsp;Ltd.Tel: +356 2277 8000<\/td><\/tr><tr><td><strong>Germany<\/strong>AstraZeneca GmbHTel: +49 41 03 7080<\/td><td><strong>The Netherlands<\/strong>AstraZeneca BVTel: +31 79 363 2222<\/td><\/tr><tr><td><strong>Eesti<\/strong>AstraZeneca Eesti O\u00dcTel: +372 6549 600<\/td><td><strong>Norway<\/strong>AstraZeneca ASTel: +47 21 00 64 00<\/td><\/tr><tr><td><strong>Greece<\/strong>AstraZeneca AE:\u0397\u03bb: +30 2 106871500<\/td><td><strong>Austria<\/strong>AstraZeneca \u00d6sterreich GmbHTel: +43 1 711 31 0<\/td><\/tr><tr><td><strong>Spain<\/strong>AstraZeneca Pharmac\u00e9utica Spain, SATel: +34 91 301 91 00<\/td><td><strong>Poland<\/strong>AstraZeneca Pharma Poland Sp.&nbsp;z ooTel .: +48 22 245 73 00<\/td><\/tr><tr><td><strong>France<\/strong>AstraZenecaTel: +33 1 41 29 40 00<\/td><td><strong>Portugal<\/strong>AstraZeneca Pharmaceutical Products, Lda.Tel: +351 21 434 61 00<\/td><\/tr><tr><td><strong>Croatia<\/strong>AstraZeneca dooTel: +385 1 4628 000<\/td><td><strong>Romania<\/strong>AstraZeneca Pharma SRLTel: +40 21 317 60 41<\/td><\/tr><tr><td><strong>Ireland<\/strong>AstraZeneca Pharmaceuticals (Ireland) DACTel: +353 1609 7100<\/td><td><strong>Slovenia<\/strong>AstraZeneca UK LimitedTel: +386 1 51 35 600<\/td><\/tr><tr><td><strong>Iceland<\/strong>Vistor hf.Phone: +354 535 7000<\/td><td><strong>Slovak Republic<\/strong>AstraZeneca AB ozTel: +421 2 5737 7777<\/td><\/tr><tr><td><strong>Italy<\/strong>AstraZeneca SpATel: +39 02 98011<\/td><td><strong>Finland \/ Finland<\/strong>AstraZeneca OyPuh \/ Tel: +358 10 23 010<\/td><\/tr><tr><td><strong>Latvia<\/strong>SIA AstraZeneca AB LatviaTel: +371 67321747<\/td><td><strong>United Kingdom<\/strong>AstraZeneca UK LtdTel: +44 1582 836 8<\/td><\/tr><\/tbody><\/table><\/figure>\n","protected":false},"excerpt":{"rendered":"<p> nasal spray suspension<br \/>\nA vaccine against influenza (live attenuated, nasal)<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2206,2200],"tags":[2697,2699,2700,2698,993,2212,998,2294,2356,2696],"class_list":["post-8905","post","type-post","status-publish","format-standard","hentry","category-f","category-medicines","tag-fluenz-tetra","tag-fluenz-tetra-dose","tag-fluenz-tetra-side-effects","tag-fluenz-tetra-uses","tag-influenza","tag-medicine","tag-nasal-spray","tag-suspension","tag-vaccine","tag-vaccine-against-influenza"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8905","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=8905"}],"version-history":[{"count":6,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8905\/revisions"}],"predecessor-version":[{"id":10024,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8905\/revisions\/10024"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=8905"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=8905"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=8905"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}