{"id":8893,"date":"2021-03-20T10:42:52","date_gmt":"2021-03-20T10:42:52","guid":{"rendered":"https:\/\/zeepedia.com\/?p=8893"},"modified":"2021-04-12T14:49:07","modified_gmt":"2021-04-12T14:49:07","slug":"fludarabin-actavis","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/fludarabin-actavis\/","title":{"rendered":"Fludarabin Actavis &#8211; Fludarabine Phosphate uses, dose and side effects"},"content":{"rendered":"\n<p>\n\n25 mg \/ ml concentrate for solution for injection \/ infusion<br>fludarabine phosphate<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Fludarabine Actavis is and what it is used for<\/h2>\n\n\n\n<p>Fludarabine Actavis is an anti-cancer drug.<br><\/p>\n\n\n\n<p>Fludarabine Actavis is used for treating&nbsp;chronic&nbsp;B-cell&nbsp;lymphocytic&nbsp;leukemia&nbsp;(B-&nbsp;CLL&nbsp;) in patients with adequate blood cell production.&nbsp;This form of cancer affects a type of&nbsp;white blood cell&nbsp;(so-called&nbsp;lymphocytes&nbsp;).<br><\/p>\n\n\n\n<p>Treatment of&nbsp;chronic lymphocytic leukemia&nbsp;with Fludarabine Actavis should only be started in patients with advanced disease with disease-related symptoms or signs of worsening of the disease.<br><\/p>\n\n\n\n<p>Fludarabine phosphate contained in Fludarabine Actavis may also be approved for the treatment of other conditions not mentioned in this product information.&nbsp;Ask your doctor, pharmacist, or other healthcare professional if you have any further questions, and always follow their instructions.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you use Fludarabine Actavis<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Fludarabine Actavis<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to fludarabine phosphate or any of the other ingredients of this medicine (listed in section 6).<\/li><li>if you are breast-feeding<\/li><li>if you have severe renal impairment<\/li><li>if you have&nbsp;red blood cell deficiency, due to a certain type of&nbsp;anemia&nbsp;(decompensated&nbsp;hemolytic anemia&nbsp;).&nbsp;Your doctor will inform you if you have this disease.<\/li><\/ul>\n\n\n\n<p><strong>Warnings and cautions<\/strong><\/p>\n\n\n\n<p>Talk to your doctor or nurse before using fludarabine phosphate if:<br><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>you have impaired liver function.&nbsp;Your doctor may then prescribe this medicine with caution.<\/li><li>you have some kind of kidney disease.&nbsp;Your kidney function should then be checked regularly.&nbsp;If the kidneys are found not to function normally, this medicine may need to be given in a lower&nbsp;dose.&nbsp;If your kidney function is severely impaired, you will not receive this medicine.&nbsp;Patients 65 years of age or older should have their kidney function checked before starting treatment.<\/li><li>you do not feel well.&nbsp;Your doctor may decide not to give this medicine, or give this medicine with caution.&nbsp;This is important if your&nbsp;bone marrow is&nbsp;not functioning normally or if you are susceptible to infection.<\/li><li>you get unusual bruises, bleed more than usual after injury, or if you suffer from&nbsp;an infection.&nbsp;The number of normal blood cells may be low and you may need to take blood samples regularly during treatment.<\/li><li>The disease itself and the treatment can cause a decrease in the number of blood cells and your immune system can attack other parts of the body (an&nbsp;autoimmune&nbsp;disease), it can also attack the red&nbsp;blood cells&nbsp;(so-called &#8220;autoimmune hemolysis&#8221;).&nbsp;This condition can be life-threatening.&nbsp;If you develop this condition, additional medications may be needed, such as&nbsp;blood transfusions&nbsp;(radiation-treated blood, see below) and&nbsp;cortisone.<\/li><li>If you need a&nbsp;blood transfusion&nbsp;and are being treated (or have been previously treated) with this medicine, tell your doctor.&nbsp;He will then make sure that you will receive blood that has undergone special treatment (irradiated).&nbsp;There have been severe complications, even with fatal outcomes, after non-irradiated blood was given.<\/li><li>If you need to have&nbsp;your&nbsp;stem cell&nbsp;collected and treated with (or have been treated with) this medicine, tell your doctor.<\/li><li>There is only limited information on the effects of Fludarabine Actavis in patients 75 years of age or older.&nbsp;Your doctor will use the medicine with caution if you are in this age group.<\/li><li>If you have very severe&nbsp;chronic lymphocytic leukemia, your body may not be able to get rid of the waste products from the cells destroyed by Fludarabine Actavis.&nbsp;This is called tumor lysis syndrome and can cause dehydration,&nbsp;kidney failure,&nbsp;and heart problems.&nbsp;Your doctor is aware of this and may prescribe other medicines to prevent this from happening.<\/li><li>If you experience any abnormal symptoms coming from the nervous system, tell your doctor.&nbsp;This is because when using a&nbsp;dose&nbsp;that is four times higher than recommended, severe symptoms from the&nbsp;central nervous system&nbsp;(brain and spinal cord) such as blindness,&nbsp;coma,&nbsp;and death&nbsp;have been reported.<\/li><li>Tell your doctor if you notice any skin changes either while you are taking this medicine or after you have finished your treatment.&nbsp;The doctor should examine the severity of the skin changes.&nbsp;If you have skin cancer, the damaged parts of the skin may deteriorate further when you use this medicine.<\/li><li>Men and women of&nbsp;childbearing potential&nbsp;must use reliable contraception during treatment and at least 6 months after stopping treatment.<\/li><li>Discuss with your doctor if you need to be vaccinated.&nbsp;Live vaccines should be avoided during and after treatment with Fludarabine Actavis.<\/li><\/ul>\n\n\n\n<p><strong>Children and young people<\/strong><\/p>\n\n\n\n<p>Fludarabine Actavis is not recommended for use in children and adolescents below 18 years.&nbsp;There is no information available for the use of Fludarabine Actavis in children.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Fludarabine Actavis<\/h2>\n\n\n\n<p>Tell your doctor if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n<p>It is especially important to tell your doctor about:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Pentostatin&nbsp;<\/strong><em>(deoxycoformycin)<\/em>, which is also used to treat B-&nbsp;KLL.&nbsp;Taking these two medicines together can cause severe lung problems (which can be life-threatening), so the combination with Fludarabine Actavis is not recommended.<\/li><li><strong>Dipyridamole<\/strong>&nbsp;(or other similar substances), used to prevent blood clots.&nbsp;They may reduce the effect of Fludarabine Actavis.<\/li><li><strong>Cytarabine<\/strong>&nbsp;(&nbsp;<em>Ara-C<\/em>&nbsp;), used to treat&nbsp;chronic lymphocytic leukemia.&nbsp;If Fludarabine Actavis is combined with cytarabine, the active form of cytarabine (&nbsp;<em>Ara-CTP<\/em>&nbsp;) may increase in leukemia cells.&nbsp;However, the overall level of cytarabine in the blood and&nbsp;elimination&nbsp;from the blood did not appear to have changed.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n<p>If you are pregnant or breast-feeding, think you may be pregnant, or are planning to have a baby, ask your doctor for advice before using this medicine.<br><\/p>\n\n\n\n<p>Fludarabine Actavis treatment can harm the unborn baby.&nbsp;You should not be given Fludarabine Actavis if you are pregnant unless necessary, and if the potential benefits outweigh the possible risks to the unborn baby.&nbsp;If you are a woman of&nbsp;childbearing potential, you must avoid becoming pregnant during treatment and for at least 6 months after stopping treatment.&nbsp;Tell your doctor immediately if you become pregnant during treatment.<br><\/p>\n\n\n\n<p>Men of&nbsp;childbearing potential&nbsp;treated with Fludarabine Actavis must use reliable contraception during treatment and up to 6 months after stopping treatment.<br><\/p>\n\n\n\n<p>It is not known if the medicine is excreted in breast milk in women treated with Fludarabine Actavis.&nbsp;However, in animal studies, medicine has been found in breast milk.&nbsp;Therefore, you should not breast-feed during treatment with this medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Some people experience fatigue, weakness, visual disturbances, confusion or upset, or seizures during treatment with Fludarabine Actavis.&nbsp;Avoid driving and using machines until you are sure you are not affected.<br><\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.&nbsp;One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or&nbsp;side effects.&nbsp;Descriptions of these effects and&nbsp;side effects&nbsp;can be found in other sections.&nbsp;Read all the information in this leaflet for guidance.&nbsp;If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Fludarabine Actavis contains sodium<\/h2>\n\n\n\n<p>This medicine contains less than 1 mmol&nbsp;sodium&nbsp;(23 mg) per ml, ie essentially &#8216;sodium-free&#8217;.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Fludarabine Actavis<\/h2>\n\n\n\n<p>Fludarabine Actavis should be given under the supervision of a doctor who specializes in cancer treatment.<br><\/p>\n\n\n\n<p>The dose&nbsp;you receive depends on your body size.&nbsp;It varies depending on the body surface area.&nbsp;It is measured in square meters (m&nbsp;<sup>2<\/sup>&nbsp;) and is calculated using length and weight.&nbsp;The recommended&nbsp;dose&nbsp;is 25 mg \/ m&nbsp;<sup>2<\/sup>&nbsp;body surface area.&nbsp;It is given either as an&nbsp;injection&nbsp;or as&nbsp;an infusion&nbsp;(drip) directly into a vein once a day for 5 consecutive days every 28 days.&nbsp;The five-day regimen is repeated every 28 days until your doctor considers that the best effect has been achieved (usually after 6 rounds).&nbsp;The dose&nbsp;can be reduced or the treatment postponed depending on any&nbsp;side effects.&nbsp;If you have kidney problems or if you are over 65, your kidneys will be checked regularly.&nbsp;If your kidneys do not function normally, you may receive a lower&nbsp;dose&nbsp;of this medicine.&nbsp;If you have severe kidney function, you will not receive this medicine (see also section 2, \u201cDo not use Fludarabine Actavis\u201d).<br><\/p>\n\n\n\n<p>The safety of this medicine in children and adolescents under 18 years of age has not been established and treatment is not recommended.<br><\/p>\n\n\n\n<p>If any of the contents of Fludarabine Actavis come in contact with your skin, nose, or lips, wash thoroughly with soap and water.&nbsp;If you get the solution in your eyes, rinse thoroughly with large amounts of water.&nbsp;Avoid inhaling vapors from the solution.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you use more Fludarabine Actavis then you should &nbsp;<\/h2>\n\n\n\n<p>In case of overdose, your doctor may discontinue treatment and treat any symptoms that may occur.<\/p>\n\n\n\n<p>Symptoms of overdose may include delayed blindness,&nbsp;coma,&nbsp;and death caused by&nbsp;toxicity&nbsp;(toxicity) to the&nbsp;central nervous system.&nbsp;High&nbsp;doses&nbsp;can lead to a marked decrease in the number of blood cells.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Fludarabin Actavis<\/h2>\n\n\n\n<p>Your doctor will make a schedule for when you will receive the medicine.&nbsp;Contact your doctor immediately if you suspect you have missed a&nbsp;dose.<br><\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or nurse.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4.&nbsp;Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects,&nbsp;although not everybody gets them.<\/p>\n\n\n\n<p>If you are not sure what the&nbsp;side effects&nbsp;are, ask your doctor to explain them to you.<br><\/p>\n\n\n\n<p>Some&nbsp;side effects&nbsp;can be life-threatening.&nbsp;<strong>You must contact your doctor immediately if you notice any of the following:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Difficulty breathing, coughing, or chest pain with or without fever.&nbsp;<\/strong>These symptoms may be signs&nbsp;of a lung&nbsp;infection&nbsp;(&nbsp;pneumonia&nbsp;).<\/li><li><strong>Unusual bruising, bleeding more than usual after injury or if you appear to be susceptible to infection.&nbsp;<\/strong>These symptoms can be caused by a decreased number of&nbsp;blood cells.&nbsp;This can also lead to an increased risk of (serious)&nbsp;infections, caused by&nbsp;organisms, which do not normally cause diseases in healthy people (opportunistic&nbsp;infections&nbsp;), including a late reactivation of&nbsp;viruses&nbsp;such as&nbsp;herpes&nbsp;zoster.<\/li><li><strong>Pain in the side, blood in the urine, or decreased urine output.&nbsp;<\/strong>These symptoms may be signs of tumor lysis syndrome (see section 2 &#8220;Warnings and precautions&#8221;).<\/li><li><strong>Skin and\/or mucosal changes with&nbsp;redness,&nbsp;inflammation, blistering, and&nbsp;tissue&nbsp;degradation.&nbsp;<\/strong>These symptoms may be signs of a severe&nbsp;allergic reaction&nbsp;(&nbsp;Lyell&#8217;s syndrome,&nbsp;Stevens-Johnson&nbsp;syndrome).<\/li><li><strong>You have palpitations (if you suddenly become aware of your heartbeat) or chest pain.&nbsp;<\/strong>These symptoms may be signs of heart problems.<br><br><\/li><\/ul>\n\n\n\n<p><\/p>\n\n\n\n<p><strong>Listed below are other possible&nbsp;side effects&nbsp;according to how common they are.&nbsp;<\/strong>The rare&nbsp;side effects&nbsp;(which may affect up to 1 in 1000 people) were mainly reported after marketing.<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p><strong>Very common<\/strong>&nbsp;&nbsp;(may affect more than 1 in 10 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>The infection&nbsp;you (some serious)<\/li><li>Decreased&nbsp;white blood cell count&nbsp;(&nbsp;<em>neutropenia<\/em>&nbsp;)<\/li><li>Reduced&nbsp;red blood cell count&nbsp;(&nbsp;<em>anemia<\/em>&nbsp;)<\/li><li>Cough<\/li><li>Vomiting, diarrhea, nausea<\/li><li>Fever<\/li><li>Fatigue<\/li><li>Weakness.<\/li><\/ul>\n\n\n\n<p><strong>Common<\/strong>&nbsp;(may affect up to 1 in 10 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Other blood-related cancers (&nbsp;myelodysplastic syndrome,&nbsp;acute myeloid leukemia&nbsp;).&nbsp;Most patients with these conditions have previously, or concomitantly or later been treated with other anticancer medicines (&nbsp;<em>alkylating agents,&nbsp;topoisomerase&nbsp;inhibitors<\/em>&nbsp;) or radiation<\/li><li>Bone marrow&nbsp;<em>suppression<\/em>&nbsp;(&nbsp;<em>myelosuppression<\/em>&nbsp;)<\/li><li>Severe loss of appetite leading to weight loss (&nbsp;<em>anorexia<\/em>&nbsp;)<\/li><li>Numbness or weakness in arms and legs (&nbsp;<em>peripheral&nbsp;neuropathy<\/em>&nbsp;)<\/li><li>Visual disturbances<\/li><li>Inflammation&nbsp;of the oral mucosa (&nbsp;<em>stomatitis<\/em>&nbsp;)<\/li><li>Rash<\/li><li>Swelling due to severe fluid retention (&nbsp;<em>edema<\/em>&nbsp;)<\/li><li>Mucositis of the digestive system from the mouth to anus (&nbsp;<em>mucositis<\/em>&nbsp;)<\/li><li>Overindulge<\/li><li>General malaise.<\/li><\/ul>\n\n\n\n<p><strong>Uncommon<\/strong>&nbsp;(may affect up to 1 in 100 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Attack of the immune system on parts of the body or&nbsp;red blood cells&nbsp;(an&nbsp;<em>autoimmune disease<\/em>&nbsp;)<\/li><li>Confusion<\/li><li>Pulmonary toxicity, scar tissue throughout the lungs (&nbsp;<em>pulmonary fibrosis<\/em>&nbsp;),&nbsp;pneumonia&nbsp;(&nbsp;<em>pneumonia<\/em>&nbsp;), shortness of breath (&nbsp;<em>dyspnoea<\/em>&nbsp;)<\/li><li>Bleeding in the stomach or intestines<\/li><li>Altered levels of&nbsp;enzymes&nbsp;in the liver or&nbsp;pancreas.<\/li><\/ul>\n\n\n\n<p><strong>Rare&nbsp;<\/strong>&nbsp;(may affect up to 1 in 1000 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Diseases affecting the&nbsp;lymphatic system&nbsp;due to a viral infection (&nbsp;<em>EBV&nbsp;associated&nbsp;proliferative&nbsp;lymphatic disease<\/em>&nbsp;)<\/li><li>Coma<\/li><li>Cramps<\/li><li>Concern<\/li><li>Blindness<\/li><li>Inflammation&nbsp;or damage to the optic nerve (&nbsp;<em>optic&nbsp;neuritis&nbsp;&nbsp;optic&nbsp;neuropathy<\/em>&nbsp;)<\/li><li>Heart failure<\/li><li>Irregular heartbeat (&nbsp;<em>arrhythmia<\/em>&nbsp;)<\/li><li>Skin cancer<\/li><\/ul>\n\n\n\n<p><strong>Has been reported (occurs in an unknown number of users)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Inflammation&nbsp;of the bladder, which can cause pain when urinating, and can lead to blood in the urine (&nbsp;<em>hemorrhagic&nbsp;cystitis<\/em>&nbsp;)<\/li><li>Cerebral hemorrhage<\/li><li>Bleeding in the lungs.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Fludarabine Actavis<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p><em>Vial&nbsp;before opening:<\/em><\/p>\n\n\n\n<p>Store at 2-8 \u00b0 C.<br><\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton and vial after EXP.<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p><em>After dilution:<\/em><\/p>\n\n\n\n<p>Fludarabine Actavis diluted in 9 mg\/ml (0.9%) sodium chloride solution is stable for at least 28 days in PVC and PE bags at 2-8 \u00baC and 25 \u00b0 C under light protection.<br><\/p>\n\n\n\n<p>From a microbiological perspective, the product should be used immediately after opening.&nbsp;If not used immediately, in-use storage times and conditions before use is the responsibility of the user.&nbsp;This storage should normally not be longer than 24 hours at 2 \u00baC-8 \u00b0 C unless&nbsp;mixing&nbsp;has been performed under controlled and validated aseptic conditions.<br><\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is fludarabine phosphate.&nbsp;1 ml of concentrate contains 25 mg of fludarabine phosphate.&nbsp;Each 2 ml&nbsp;vial&nbsp;contains 50 mg of fludarabine phosphate.<\/li><li>The other ingredients are disodium phosphate dihydrate, water for injections, sodium hydroxide (for&nbsp;pH&nbsp;adjustment).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>Fludarabine Actavis is a clear, colorless, or almost colorless solution.<br><\/p>\n\n\n\n<p>The vial&nbsp;in stained glass (type I) with bromobutyl rubber stopper and metal capsule (aluminum) with polypropylene disc.&nbsp;The vial&nbsp;will be packed with or without a protective plastic film.<br><\/p>\n\n\n\n<p>Pack sizes<\/p>\n\n\n\n<p>2 ml&nbsp;vial<\/p>\n\n\n\n<p>5 x 2 ml&nbsp;vial<br><\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p>Actavis Group PTC ehf.<\/p>\n\n\n\n<p>Reykjavikurvegur 76-78<\/p>\n\n\n\n<p>I220 Hafnarfj\u00f6r\u00f0ur<\/p>\n\n\n\n<p>Iceland<br><\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Actavis Italy SpA<\/p>\n\n\n\n<p>Via Pasteur 10<\/p>\n\n\n\n<p>20014 Nerviano (Milan)<\/p>\n\n\n\n<p>Italy<br><\/p>\n","protected":false},"excerpt":{"rendered":"<p> 25 mg \/ ml concentrate for solution for injection \/ infusion<br \/>\nfludarabine phosphate<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2206,2200],"tags":[2721,2723,2724,2722,2709,2711,2712,2710,2215,2212],"class_list":["post-8893","post","type-post","status-publish","format-standard","hentry","category-f","category-medicines","tag-fludarabin-actavis","tag-fludarabin-actavis-dose","tag-fludarabin-actavis-side-effects","tag-fludarabin-actavis-uses","tag-fludarabine-phosphate","tag-fludarabine-phosphate-dose","tag-fludarabine-phosphate-side-effects","tag-fludarabine-phosphate-uses","tag-injection","tag-medicine"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8893","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=8893"}],"version-history":[{"count":5,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8893\/revisions"}],"predecessor-version":[{"id":9973,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8893\/revisions\/9973"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=8893"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=8893"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=8893"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}