{"id":8846,"date":"2021-03-19T10:47:21","date_gmt":"2021-03-19T10:47:21","guid":{"rendered":"https:\/\/zeepedia.com\/?p=8846"},"modified":"2021-04-12T14:57:14","modified_gmt":"2021-04-12T14:57:14","slug":"fluconazole-fresenius-kabi","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/fluconazole-fresenius-kabi\/","title":{"rendered":"Fluconazole Fresenius Kabi &#8211; Fluconazole uses, dose and side effects"},"content":{"rendered":"\n<p>\n\n&nbsp;mg \/ ml&nbsp;Infusion&nbsp;solution<br>fluconazole<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Fluconazole Fresenius Kabi is and what it is used for<\/h2>\n\n\n\n<p>Fluconazole Fresenius Kabi belongs to a group of medicines used to treat fungal infections.&nbsp;The active substance is&nbsp;fluconazole.<\/p>\n\n\n\n<p>Fluconazole Fresenius Kabi is used to treat&nbsp;infections&nbsp;caused by fungi, and can also be used to prevent a fungal infection.&nbsp;The most common cause of fungal infections is a yeast called&nbsp;<em>Candida<\/em>&nbsp;<\/p>\n\n\n\n<p><strong>Adults<\/strong><\/p>\n\n\n\n<p>You can get this medicine from a doctor to treat the following fungal infections:<br><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Meningitis&nbsp;caused by cryptococcus &#8211; a fungal infection of the brain<\/li><li>Coccidioidomycosis&nbsp;is &#8211; a lung disease<\/li><li>Infection&nbsp;is caused by&nbsp;<em>Candida&nbsp;<\/em>and is found in the bloodstream, internal organs (eg heart, lungs), or urinary tract.<\/li><li>A fungal infection that affects the lining of the mouth, throat and can cause mouth soreness when using a denture<\/li><\/ul>\n\n\n\n<p>You can also get Fluconazole Fresenius Kabi to:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>prevent&nbsp;recurrence of&nbsp;meningitis&nbsp;caused by cryptococci.<\/li><li>prevent the recurrence of fungal infections in the mouth<\/li><li>prevent&nbsp;infection&nbsp;caused by&nbsp;<em>Candida&nbsp;<\/em>(if you have a weakened immune system)<\/li><\/ul>\n\n\n\n<p><strong>Children and adolescents (0 to 17 years)<\/strong><\/p>\n\n\n\n<p>You can get this medicine from your doctor to treat these types of fungal infections:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Fungal infection in the mouth &#8211;&nbsp;an infection&nbsp;that affects the lining of the mouth and throat<\/li><li>Infection&nbsp;is caused by&nbsp;<em>Candida&nbsp;<\/em>and is found in the bloodstream, internal organs (eg heart, lungs), or urinary tract.<\/li><li>Meningitis&nbsp;caused by cryptococcus &#8211; a fungal infection of the brain<\/li><\/ul>\n\n\n\n<p>You can also get Fluconazole Fresenius Kabi to:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>prevent&nbsp;infection&nbsp;caused by&nbsp;<em>Candida&nbsp;<\/em>(if you have a weakened immune system).<\/li><li>prevent&nbsp;recurrence of&nbsp;meningitis&nbsp;caused by cryptococci.<\/li><\/ul>\n\n\n\n<p>Fluconazole contained&nbsp;in Fluconazole Fresenius Kabi may also be approved for the treatment of other conditions not mentioned in this leaflet.&nbsp;Ask your doctor, pharmacist, or another healthcare professional if you have any further questions, and always follow their instructions.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2. What you need to know before you get Fluconazole Fresenius Kabi<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">You should not be treated with Fluconazole Fresenius Kabi:<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to&nbsp;fluconazole&nbsp;or any of the other ingredients of this medicine (listed in section 6).<\/li><li>if you are allergic to other medicines that you have taken to treat fungal infections.&nbsp;Symptoms may include&nbsp;itching, redness of the skin, or difficulty breathing.<\/li><li>if you are taking astemizole or terfenadine (&nbsp;antihistamine&nbsp;for the treatment of&nbsp;allergies&nbsp;)<\/li><li>if you are taking cisapride (for stomach upset)<\/li><li>if you are taking pimozide (used to treat mental illness)<\/li><li>if you are taking&nbsp;quinidine&nbsp;(used to treat irregular heartbeat, &#8220;arrhythmia&#8221;)<\/li><li>if you are taking erythromycin (&nbsp;antibiotic&nbsp;to treat&nbsp;infections&nbsp;).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor, pharmacist, or nurse before receiving Fluconazole Fresenius Kabi:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have liver or kidney problems<\/li><li>if you have any heart disease, e.g.&nbsp;irregular heartbeat<\/li><li>if you have abnormal levels of&nbsp;potassium,&nbsp;calcium,&nbsp;or&nbsp;magnesium&nbsp;in your blood<\/li><li>if you develop severe skin reactions (&nbsp;itching,&nbsp;redness&nbsp;of the skin, or difficulty breathing).<\/li><li>if you develop signs of adrenal insufficiency, where the adrenal glands do not produce enough of certain steroid hormones such as&nbsp;cortisol&nbsp;(&nbsp;chronic&nbsp;or prolonged fatigue, muscle weakness, loss of appetite, weight loss, abdominal pain)<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Fluconazole Fresenius Kabi<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n<p>Tell your doctor&nbsp;<strong>immediately<\/strong>&nbsp;if you are taking astemizole, terfenadine (an&nbsp;antihistamine&nbsp;for the treatment of&nbsp;allergies&nbsp;) or cisapride (used to treat stomach upset) or pimozide (used to treat mental disorders) or&nbsp;quinidine&nbsp;(used to treat irregular heartbeat), or erythromycin (an&nbsp;antibiotic&nbsp;for the treatment of&nbsp;infections&nbsp;) as these should not be taken with Fluconazole Fresenius Kabi (see section \u201cYou should not be treated with Fluconazole Fresenius Kabi\u201d).<br><\/p>\n\n\n\n<p>Some medications can be affected by or affect Fluconazole Fresenius Kabi.<\/p>\n\n\n\n<p>Tell your doctor if you are taking any of the following medicines:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>rifampicin, rifabutin (&nbsp;antibiotics&nbsp;for&nbsp;infections&nbsp;)<\/li><li>Alfentanil,&nbsp;fentanyl&nbsp;(used as anesthetic)<\/li><li>Amitriptyline, nortriptyline (used to treat depression)<\/li><li>amphotericin B, voriconazole (for fungal infections)<\/li><li>blood-thinning drugs (eg&nbsp;warfarin&nbsp;) to prevent&nbsp;blood&nbsp;clots<\/li><li>benzodiazepines&nbsp;(eg midazolam, triazolam) used for insomnia or anxiety<\/li><li>carbamazepine,&nbsp;phenytoin&nbsp;(for&nbsp;epilepsy&nbsp;)<\/li><li>nifedipine, isradipine, amlodipine, verapamil, felodipine or&nbsp;losartan&nbsp;(for high&nbsp;blood pressure&nbsp;)<\/li><li>olaparib (used to treat ovarian cancer)<\/li><li>ciclosporin, everolimus, sirolimus or tacrolimus (used after transplants)<\/li><li>cyclophosphamide, vinca alkaloids (eg vincristine, vinblastine) used to treat cancer<\/li><li>halofantrine (against&nbsp;malaria&nbsp;)<\/li><li>statins (eg atorvastatin,&nbsp;simvastatin,&nbsp;and fluvastatin) used to lower blood cholesterol<\/li><li>methadone&nbsp;(for pain)<\/li><li>celecoxib, flurbiprofen,&nbsp;naproxen,&nbsp;ibuprofen, lornoxicam, meloxicam,&nbsp;diclofenac&nbsp;(non-steroidal anti-inflammatory drugs,&nbsp;NSAIDs&nbsp;)<\/li><li>birth control pills<\/li><li>prednisone (&nbsp;steroid&nbsp;)<\/li><li>zidovudine (also known as AZT) or saquinavir (used to treat&nbsp;HIV&nbsp;)<\/li><li>drugs against&nbsp;diabetes&nbsp;as chlorpropamide, glibenclamide, glipizide or tolbutamide<\/li><li>theophylline (for&nbsp;asthma&nbsp;)<\/li><li>tofacitinib (for&nbsp;rheumatoid arthritis&nbsp;)<\/li><li>A&nbsp;vitamin&nbsp;(nutritional supplements)<\/li><li>Ivacaftor (used to treat&nbsp;cystic fibrosis&nbsp;)<\/li><li>amiodarone&nbsp;(used to treat irregular heartbeat, &#8220;arrhythmia&#8221;)<\/li><li>hydrochlorothiazide&nbsp;(diuretic)<\/li><li>ibrutinib (used to treat blood cancer)<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breast-feeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n<p>You should not take Fluconazole Fresenius Kabi when you are pregnant unless your doctor tells you to.<\/p>\n\n\n\n<p>You can continue breastfeeding after taking a single dose of 150 mg Fluconazole Fresenius Kabi.<\/p>\n\n\n\n<p>You should not breast-feed if you take repeated&nbsp;doses&nbsp;of Fluconazole Fresenius Kabi.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>When driving a vehicle or using machines, keep in mind that you may experience dizziness or seizures during treatment.<br><\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.&nbsp;One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or&nbsp;side effects.&nbsp;Descriptions of these effects and&nbsp;side effects&nbsp;can be found in other sections.&nbsp;Read all the information in this leaflet for guidance.&nbsp;If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Fluconazole Fresenius Kabi contains sodium<\/h2>\n\n\n\n<p>This medicinal product contains 177\/354\/708 mg&nbsp;sodium&nbsp;(the main ingredient in table salt\/table salt) per 50\/100\/200 ml.&nbsp;This corresponds to 8.85 \/ 17.7 \/ 35.4% of the highest recommended daily intake of&nbsp;sodium&nbsp;for adults.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How Fluconazole Fresenius Kabi is given<\/h2>\n\n\n\n<p>Always use this medicine exactly as your doctor or pharmacist has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p>This medicine will be given to you by a doctor or nurse as a slow&nbsp;injection&nbsp;(&nbsp;infusion&nbsp;) into a vein.&nbsp;Fluconazole Fresenius Kabi is provided as a solution and will not be further diluted.&nbsp;There is more information for healthcare professionals in the last section of the package leaflet.<br><\/p>\n\n\n\n<p>The table below shows the recommended&nbsp;doses&nbsp;for different&nbsp;infections.&nbsp;Ask your doctor or nurse if you are not sure why you are getting Fluconazole Fresenius Kabi.<br><\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><thead><tr><td><strong>Infection<\/strong><\/td><td><strong>Dose<\/strong><\/td><\/tr><\/thead><tbody><tr><td>To treat&nbsp;meningitis&nbsp;caused by cryptococci<\/td><td>400 mg on the first day, then 200 mg to 400 mg once daily for 6 to 8 weeks or longer as needed.&nbsp;Sometimes the&nbsp;dose is&nbsp;increased&nbsp;by up to 800 mg<\/td><\/tr><tr><td>To prevent&nbsp;recurrence of&nbsp;meningitis&nbsp;caused by cryptococci<\/td><td>200 mg once daily until your doctor tells you to stop<\/td><\/tr><tr><td>To treat&nbsp;coccidioidomycosis<\/td><td>200 mg to 400 mg once daily from 11 months up to 24 months or longer if needed.&nbsp;Sometimes the&nbsp;dose is&nbsp;increased&nbsp;by up to 800 mg<\/td><\/tr><tr><td>To treat internal fungal infections caused by&nbsp;<em>Candida<\/em><\/td><td>800 mg on the first day, then 400 mg once daily until your doctor tells you to stop<\/td><\/tr><tr><td>Fungal infection of the mouth affects the lining of the mouth, throat and can cause&nbsp;inflammation&nbsp;of the oral mucosa when using a denture<\/td><td>200 mg to 400 mg on the first day, then 100 mg to 200 mg until your doctor tells you to stop<\/td><\/tr><tr><td>To treat a fungal infection in the mouth (cod) &#8211;&nbsp;dose&nbsp;one depends on exactly where the&nbsp;infection&nbsp;is<\/td><td>50 mg to 400 mg once daily for 7 to 30 days until your doctor tells you to stop<\/td><\/tr><tr><td>To prevent the recurrence of fungal infections that affect the mucous membranes of the mouth and throat<\/td><td>100 mg to 200 mg once daily or 200 mg three times a week as long as you are at risk of getting an&nbsp;infection<\/td><\/tr><tr><td>To prevent&nbsp;infection&nbsp;caused by&nbsp;Candida&nbsp;(if you have a weakened immune system)<\/td><td>200 mg to 400 mg once daily as long as you are at risk of getting an&nbsp;infection<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<h2 class=\"wp-block-heading\">Use in adolescents between 12 and 17 years of age<\/h2>\n\n\n\n<p>Use&nbsp;dose&nbsp;one prescribed by your doctor (according to the recommendations for either adults or children).<br><\/p>\n\n\n\n<p><strong>Use in children up to 11 years<\/strong><\/p>\n\n\n\n<p>The maximum&nbsp;dose&nbsp;for children is 400 mg daily.<\/p>\n\n\n\n<p>Dose&nbsp;one is based on the child&#8217;s weight in kg. <\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong>Infection<\/strong><\/td><td><strong>Daily&nbsp;dose<\/strong><\/td><\/tr><tr><td>Fungal infections of the mouth and throat infections caused by&nbsp;<em>Candida&nbsp;<\/em>&#8211;&nbsp;dose,&nbsp;and duration of treatment depends on how severe the&nbsp;infection&nbsp;is and where it is located<\/td><td>3 mg per kg body weight once daily (6 mg per kg body weight can be given on the first day)<\/td><\/tr><tr><td>Meningitis&nbsp;caused by cryptococcus or internal fungal infections caused by&nbsp;<em>Candida<\/em><\/td><td>6 mg to 12 mg per kg body weight once daily<\/td><\/tr><tr><td>To prevent the recurrence of&nbsp;meningitis&nbsp;caused by cryptococci<\/td><td>6 mg per kg body weight once daily<\/td><\/tr><tr><td>To prevent the child from getting an&nbsp;infection&nbsp;caused by&nbsp;<em>Candida&nbsp;<\/em>(if the child has a weakened immune system)<\/td><td>3 mg to 12 mg per kg body weight once daily<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p><strong>Use in infants between 0 and 4 weeks<\/strong><br><\/p>\n\n\n\n<p>Infants between 15 and 27 days:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>The same&nbsp;dose&nbsp;as above is given every other day.&nbsp;The maximum&nbsp;dose&nbsp;is 12 mg per kg body weight every other day (48 hours).<\/li><\/ul>\n\n\n\n<p>Infants 0-14 days:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>The same&nbsp;dose&nbsp;as above is given every three days.&nbsp;The maximum&nbsp;dose&nbsp;is 12 mg per kg body weight every three days (72 hours).<\/li><\/ul>\n\n\n\n<p>Your doctor may&nbsp;prescribe&nbsp;you&nbsp;other&nbsp;doses&nbsp;than those listed here.&nbsp;Always use Fluconazole Fresenius Kabi exactly as your doctor has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p><strong>Older<\/strong><\/p>\n\n\n\n<p>The usual&nbsp;dose&nbsp;for adults can be used unless you have kidney problems.<br><\/p>\n\n\n\n<p><strong>Patients with&nbsp;renal failure<\/strong><\/p>\n\n\n\n<p>Your doctor may change the&nbsp;dose&nbsp;depending on your kidney function.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you take more Fluconazole Fresenius Kabi then you should<\/h2>\n\n\n\n<p>If you are concerned that you have received too much Fluconazole Fresenius Kabi, or if, for example, a child has accidentally ingested the medicine, tell your doctor or nurse immediately, or contact the Poison Information Center to assess the risk and advice.&nbsp;The symptoms of a possible overdose may be that you start hearing, seeing, feeling, and thinking things that are not real (hallucinations and paranoid behaviors).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If a dose of Fluconazole Fresenius Kabi has been missed<\/h2>\n\n\n\n<p>As you will receive this medicine under close medical supervision, it is unlikely that a&nbsp;dose will be&nbsp;missed.&nbsp;Talk to your doctor or pharmacist if you think a&nbsp;dose&nbsp;has been missed.<br><\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor, pharmacist, or nurse.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects, although not everybody gets them.<\/p>\n\n\n\n<p>Some people develop&nbsp;<strong>allergic reactions<\/strong>, although severe allergic reactions are rare<strong>.&nbsp;<\/strong>If you get any of the following symptoms<strong>, contact your doctor immediately.<\/strong><br><\/p>\n\n\n\n<p>Common&nbsp;side effects&nbsp;(may affect up to 1 in 10 people) are:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>rash<\/li><\/ul>\n\n\n\n<p>Uncommon&nbsp;side effects&nbsp;(may affect up to 1 in 100 people) are:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>itching&nbsp;all over the body, reddening of the skin or itchy, red spots<\/li><\/ul>\n\n\n\n<p>Rare&nbsp;side effects&nbsp;(may affect up to 1 in 1,000 people) are:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>sudden wheezing, difficulty breathing, or a tight feeling in the chest<\/li><li>swelling of the eyelids, face, or lips<\/li><li>severe skin reactions, e.g.&nbsp;a rash with blistering (this can affect the mouth and tongue).<\/li><\/ul>\n\n\n\n<p>If any of these occur, stop using Fluconazole Fresenius Kabi and&nbsp;<strong>contact your doctor immediately.<\/strong><br><\/p>\n\n\n\n<p>Fluconazole Fresenius Kabi can affect your liver.&nbsp;Signs of hepatic impairment include:<br><\/p>\n\n\n\n<p>Common&nbsp;side effects&nbsp;(may affect up to 1 in 10 people) are:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>vomiting<\/li><\/ul>\n\n\n\n<p>Uncommon&nbsp;side effects&nbsp;(may affect up to 1 in 100 people) are:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>fatigue<\/li><li>decreased appetite<\/li><li>yellowish skin or yellowish whites of the eyes (jaundice)<\/li><\/ul>\n\n\n\n<p>Fluconazole Fresenius Kabi can also affect other organ systems, which can cause the following symptoms:<br><\/p>\n\n\n\n<p>Uncommon&nbsp;side effects&nbsp;(may affect up to 1 in 100 people) are:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>cramps<\/li><\/ul>\n\n\n\n<p>Rare&nbsp;side effects&nbsp;(may affect up to 1 in 1,000 people) are:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>decreased number of&nbsp;white blood cells&nbsp;that help defend the body against&nbsp;infection&nbsp;and decreased number of&nbsp;blood cells&nbsp;that help stop bleeding, leading to unexpected bruising or bleeding, sudden fever, sore throat, sore mouth<\/li><\/ul>\n\n\n\n<p>If any of these occur, stop using Fluconazole Fresenius Kabi and&nbsp;<strong>contact your doctor immediately.<\/strong><br><\/p>\n\n\n\n<p><strong>Other&nbsp;side effects&nbsp;are<\/strong><\/p>\n\n\n\n<p>If any of the&nbsp;side effects&nbsp;gets serious, or if you notice any&nbsp;side effects&nbsp;not listed in this leaflet, please tell your doctor or pharmacist.<br><\/p>\n\n\n\n<p>Common&nbsp;side effects&nbsp;(may affect up to 1 in 10 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>headache<\/li><li>feeling uncomfortable in the stomach, diarrhea, nausea<\/li><li>elevated liver values<\/li><li>rash<\/li><\/ul>\n\n\n\n<p>Uncommon&nbsp;side effects&nbsp;(may affect up to 1 in 100 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>decreased amount of&nbsp;red blood cells&nbsp;which can lead to pale skin and cause weakness and shortness of breath<\/li><li>difficulty sleeping, drowsiness<\/li><li>dizziness, tingling sensation, and crawling, tingling or numbness, taste changes<\/li><li>constipation, indigestion, gas tension,&nbsp;dry mouth<\/li><li>muscle pain<\/li><li>liver damage<\/li><li>streaks in the skin, blistering (&nbsp;hives&nbsp;),&nbsp;itching, sweating<\/li><li>general malaise, fever<\/li><\/ul>\n\n\n\n<p>Rare&nbsp;side effects&nbsp;(may affect up to 1 in 1,000 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>red or purple discoloration of the skin that may be caused by decreased&nbsp;platelet count&nbsp;or other changes in the blood<\/li><li>elevated blood cholesterol and blood fat levels<\/li><li>shaking<\/li><li>decreased level of&nbsp;potassium&nbsp;in the blood<\/li><li>abnormal&nbsp;ECG, changes in&nbsp;heart rate&nbsp;or heart rate<\/li><li>liver failure<\/li><li>hair loss<\/li><\/ul>\n\n\n\n<p>No known frequency but may occur (cannot be calculated from the available data):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>hypersensitivity reaction&nbsp;with skin rash, fever, swollen&nbsp;glands, increased amount of a&nbsp;white blood cell&nbsp;type&nbsp;(&nbsp;eosinophilia&nbsp;), and&nbsp;inflammation&nbsp;of internal organs (liver, lungs, heart, kidneys, and colon) (so-called &#8220;drug reaction with&nbsp;eosinophilia&nbsp;and systemic symptoms&#8221;, (DRESS )).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Fluconazole Fresenius Kabi<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<br><\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton and label after EXP.&nbsp;The expiration date is the last day of the specified month.<br><\/p>\n\n\n\n<p>Bags (free&nbsp;<em>flex<\/em>&nbsp;):&nbsp;Do not store above&nbsp;25 \u00b0 C.&nbsp;Do not freeze.<\/p>\n\n\n\n<p>Bottles (KabiPac): Do not freeze.<br><\/p>\n\n\n\n<p>The medicine must be used immediately after opening the bottle or bag.<br><\/p>\n\n\n\n<p>Do not use this medicine if you notice that the solution is not clear or if you see visible particles.<br><\/p>\n\n\n\n<p>Do not use it if the bottle or bag is damaged.<br><\/p>\n\n\n\n<p>The bottles or bags are for single use only.&nbsp;Once used, the bottles or bags and any remaining medicine should be discarded.<br><\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is&nbsp;fluconazole.&nbsp;Each ml contains 2 mg of&nbsp;fluconazole<\/li><li>The other ingredients are: sodium chloride, water for injections, and sodium hydroxide or&nbsp;hydrochloric acid&nbsp;(for&nbsp;pH&nbsp;adjustment)<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Fluconazole Fresenius Kabi is a clear, colorless solution with no visible particles.<\/li><li>Pack sizes:<\/li><\/ul>\n\n\n\n<p>1, 10, 20, 25, 30, 40, 50, 60 bottles \/ bags x 50 ml with 100 mg&nbsp;fluconazole<br>1, 10, 20, 25, 30, 40, 50, 60 bottles \/ bags x 100 ml with 200 mg&nbsp;fluconazole<br>1, 10, 20, 25, 30, 40 bottles \/ bags x 200 ml with 400 mg&nbsp;fluconazole<br><\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p><strong>Marketing Authorisation Holder<\/strong><\/p>\n\n\n\n<p>Fresenius Kabi AB<\/p>\n\n\n\n<p>751 74 Uppsala<br><\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Bottles (KabiPac)<\/p>\n\n\n\n<p>Fresenius Kabi Polska Sp.&nbsp;z oo<\/p>\n\n\n\n<p>ul.&nbsp;Sienkiewicza 25, 99-300 Kutno<\/p>\n\n\n\n<p>Poland<br><\/p>\n\n\n\n<p>and<br><\/p>\n\n\n\n<p>Bags (free&nbsp;<em>flex<\/em>&nbsp;).<\/p>\n\n\n\n<p>Fresenius Kabi France<\/p>\n\n\n\n<p>6, Rue de Rempart<\/p>\n\n\n\n<p>F-27400 Louviers<\/p>\n\n\n\n<p>France<\/p>\n","protected":false},"excerpt":{"rendered":"<p>  mg \/ ml Infusion solution<br \/>\nfluconazole<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2206,2200],"tags":[2729,2731,2741,2743,2744,2742,2732,2730,2235,2212],"class_list":["post-8846","post","type-post","status-publish","format-standard","hentry","category-f","category-medicines","tag-fluconazole","tag-fluconazole-dose","tag-fluconazole-fresenius-kabi","tag-fluconazole-fresenius-kabi-dose","tag-fluconazole-fresenius-kabi-side-effects","tag-fluconazole-fresenius-kabi-uses","tag-fluconazole-side-effects","tag-fluconazole-uses","tag-infusion","tag-medicine"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8846","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=8846"}],"version-history":[{"count":5,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8846\/revisions"}],"predecessor-version":[{"id":9992,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8846\/revisions\/9992"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=8846"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=8846"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=8846"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}