{"id":8834,"date":"2021-03-19T10:36:48","date_gmt":"2021-03-19T10:36:48","guid":{"rendered":"https:\/\/zeepedia.com\/?p=8834"},"modified":"2021-04-12T15:09:05","modified_gmt":"2021-04-12T15:09:05","slug":"flucloxacillin-sandoz","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/flucloxacillin-sandoz\/","title":{"rendered":"Flucloxacillin Sandoz &#8211; Flucloxacillin uses, dose and side effects"},"content":{"rendered":"\n<p>\n\n500 mg, 750 mg&nbsp;film-coated tablets<br>flucloxacillin<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Flucloxacillin Sandoz is and what it is used for<\/h2>\n\n\n\n<p>Flucloxacillin Sandoz is penicillin&nbsp;(antibacterial drug), which prevents the bacterium from building a normal cell wall.&nbsp;Without a functioning cell wall, the bacterium dies quickly.&nbsp;Flucloxacillin Sandoz differs from regular&nbsp;penicillin&nbsp;in that it is stable to an&nbsp;enzyme&nbsp;(&nbsp;beta-lactamase&nbsp;), which has the ability to break down regular&nbsp;penicillin.<br><\/p>\n\n\n\n<p>Flucloxacillin Sandoz is used against&nbsp;infection&nbsp;in the skin and soft tissues as well as&nbsp;infectious&nbsp;you in the joints, bones, and lungs.<br><\/p>\n\n\n\n<p>Flucloxacillin contained in Flucloxacillin Sandoz may also be approved for the treatment of other conditions not mentioned in this product information.&nbsp;Ask your doctor, pharmacist, or another healthcare professional if you have any further questions, and always follow their instructions.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2. What you need to know before you use Flucloxacillin Sandoz<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Flucloxacillin Sandoz<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>If you are allergic to flucloxacillin, other&nbsp;penicillins,&nbsp;or any of the other ingredients of this medicine (listed in section 6)<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before using Flucloxacillin Sandoz.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are hypersensitive to&nbsp;cephalosporins&nbsp;(another group of&nbsp;antibacterial&nbsp;drugs)<\/li><li>there is a risk of diarrhea and colon infection.&nbsp;If you have problems with diarrhea, you should therefore consult a doctor.<\/li><li>there is a risk of liver damage, it is rare but probably increases with older age and with longer treatment.<\/li><li>if you are taking or will be taking&nbsp;paracetamol.<\/li><\/ul>\n\n\n\n<p>With concomitant use of flucloxacillin and&nbsp;paracetamol, there is a risk of blood and fluid disturbances (metabolic&nbsp;acidosis&nbsp;due to high anion gap, so-called HAGMA), which occurs when the acidity of blood plasma increases, especially in certain patient groups who are at increased risk, e.g.&nbsp;patients with severe renal impairment, sepsis or malnutrition and especially when using maximum daily doses of&nbsp;paracetamol.&nbsp;HAGMA is a serious condition that requires urgent treatment.<br><\/p>\n\n\n\n<p>The use of flucloxacillin, especially in high&nbsp;doses, may lower blood potassium levels (&nbsp;hypokalaemia&nbsp;).&nbsp;Your doctor may want to measure your potassium levels regularly during treatment with higher&nbsp;doses&nbsp;of flucloxacillin.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Flucloxacillin Sandoz<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.&nbsp;This is because certain medicines can affect or be affected by the treatment with Flucloxacillin Sandoz, for example, certain medicines:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>against&nbsp;tumors&nbsp;and disorders of the immune system (methotrexate)<\/li><li>against&nbsp;gout&nbsp;(probenecid)<\/li><li>certain blood thinners (&nbsp;warfarin&nbsp;)<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Flucloxacillin Sandoz with food and drink<\/h2>\n\n\n\n<p>Flucloxacillin Sandoz has the best effect if the medicine is taken between meals.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breast-feeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<br><\/p>\n\n\n\n<p>No known risks when used during pregnancy.<br><\/p>\n\n\n\n<p>Flucloxacillin passes into breast milk but is unlikely to affect breastfed infants.&nbsp;However, consult a physician when using Flucloxacillin Sandoz during breast-feeding.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>No known effect on the ability to drive or use machines.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.&nbsp;One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or&nbsp;side effects.&nbsp;Descriptions of these effects and&nbsp;side effects&nbsp;can be found in other sections.&nbsp;Read all the information in this leaflet for guidance.&nbsp;If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Flucloxacillin Sandoz contains sodium<\/h2>\n\n\n\n<p>Flucloxacillin Sandoz 500 mg contains 29.9 mg&nbsp;sodium&nbsp;(the main ingredient in table salt\/table salt) per tablet and Flucloxacillin Sandoz 750 mg contains 44.8 mg&nbsp;sodium&nbsp;per tablet.&nbsp;This corresponds to 1.49% for 500 mg and 2.24% for 750 mg of the highest recommended daily&nbsp;sodium&nbsp;intake&nbsp;for adults.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. How to use Flucloxacillin Sandoz<\/h2>\n\n\n\n<p>Always take this medicine exactly as your doctor or pharmacist has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<br><\/p>\n\n\n\n<p>Take flucloxacillin tablets at least 1 hour before or 2 hours after a meal.<br><\/p>\n\n\n\n<p>To reduce the risk of esophageal pain, swallow the tablet with a full glass of water (250 ml).&nbsp;Do not lie down immediately after taking the tablet.<br><\/p>\n\n\n\n<p>Your doctor will decide which&nbsp;dose&nbsp;is right for you.&nbsp;Even if you feel better after just a few days, you must take the entire Flucloxacillin Sandoz regimen as&nbsp;prescribed.&nbsp;Otherwise, some bacteria may survive for a while, grow and cause a new outbreak of&nbsp;infection.<\/p>\n\n\n\n<p>The tablet can be divided into two equal parts.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you take more Flucloxacillin Sandoz then you should<\/h2>\n\n\n\n<p>If you have ingested too much medicine or if e.g.&nbsp;If a child has inadvertently ingested the medicine, contact a doctor, hospital, or the Poison Information Center for risk assessment and advice.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Flucloxacillin Sandoz<\/h2>\n\n\n\n<p>If you forget to take a&nbsp;dose, take it as soon as possible.&nbsp;Then continue as before.&nbsp;Do not take a double&nbsp;dose&nbsp;to make up for a forgotten tablet.<br><\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects, although not everybody gets them.<br><\/p>\n\n\n\n<p>Flucloxacillin Sandoz may in rare cases affect the white&nbsp;blood cells&nbsp;so that the defense of infection deteriorates.&nbsp;If you get an&nbsp;infection&nbsp;with symptoms such as fever with severe general deterioration or fever with local infection symptoms such as sore throat\/pharynx\/mouth or urination problems, you should see a doctor as soon as possible so that blood tests can rule out a lack of&nbsp;white blood cells&nbsp;(&nbsp;agranulocytosis, may affect up to 1 in 1000 users).&nbsp;It is important that you then information about your medication.<br><\/p>\n\n\n\n<p>Flucloxacillin Sandoz may in rare cases cause a severe&nbsp;acute&nbsp;allergic reaction&nbsp;(&nbsp;anaphylactic reaction&nbsp;).&nbsp;Such a reaction can be life-threatening.&nbsp;If one or more of the following symptoms occur, healthcare should be contacted immediately.&nbsp;The symptoms of such a reaction may be reddening of the skin, itchy hives (&nbsp;urticaria&nbsp;), shortness of breath, and dizziness.<br><\/p>\n\n\n\n<p>In case of prolonged or severe diarrhea, you should consult a doctor.<br><\/p>\n\n\n\n<p>Common (may affect up to 1 in 10 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Stomach upset, mainly nausea or diarrhea.<\/li><li>Rash.<\/li><\/ul>\n\n\n\n<p>Uncommon (may affect up to 1 in 100 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Hives.<\/li><li>Blood picture change (&nbsp;eosinophilia&nbsp;).<\/li><\/ul>\n\n\n\n<p>Rare (may affect up to 1 in 1,000 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Inflammation of the colon.<\/li><li>Liver effects.<\/li><\/ul>\n\n\n\n<p>Very rare (may affect up to 1 in 10,000 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Itching.<\/li><li>Very rare cases of blood and fluid disturbances (metabolic&nbsp;acidosis&nbsp;due to high anion gap), which occur when the acidity of blood plasma increases, with concomitant use of flucloxacillin and&nbsp;paracetamol, usually in patients with risk factors (see section 2).<\/li><\/ul>\n\n\n\n<p>Has been reported (occurs in an unknown number of users):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Dizziness, abdominal pain, vomiting.<\/li><li>Serious skin side effects: red, scaly rash with lumps under the skin and blisters (exanthematous&nbsp;pustulosis&nbsp;).&nbsp;Contact a doctor immediately if you get any of these symptoms.<\/li><li>Low potassium levels in the blood (&nbsp;hypokalaemia&nbsp;) can cause muscle weakness, twitching, or abnormal heart rhythm.<\/li><li>Pain in the esophagus and other related symptoms, such as difficulty swallowing, heartburn, throat irritation, and chest pain.<\/li><\/ul>\n\n\n\n<p>Itching&nbsp;in the abdomen can be caused by fungal overgrowth.<\/p>\n\n\n\n<p>White coating in the mouth mainly on the tongue can also be caused by a fungal infection.<br><\/p>\n\n\n\n<p>There is a risk of liver damage, it is rare but probably increases with older age and with longer treatment.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Flucloxacillin Sandoz<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<br><\/p>\n\n\n\n<p>Do not store above 25 \u00b0 C.<br><\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton or blister after EXP.&nbsp;The expiration date is the last day of the specified month.<br><\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is flucloxacillin sodium monohydrate corresponding to flucloxacillin 500 mg and 750 mg respectively.<\/li><li>The other ingredients are microcrystalline cellulose, povidone, magnesium stearate,&nbsp;colloidal&nbsp;anhydrous silica, croscarmellose sodium, titanium dioxide (E171), hypromellose, macrogol, methylcellulose, and carnauba wax.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>Flucloxacillin Sandoz 500 mg: White, oblong, biconvex tablet marked with \u201cF 500\u201d on one side and with a scoreline on the other side.<br><\/p>\n\n\n\n<p>Flucloxacillin Sandoz 750 mg: White, oblong, biconvex tablet marked with \u201cF 750\u201d on one side and with a scoreline on the other side.<br><\/p>\n\n\n\n<p><em>Pack sizes<\/em><\/p>\n\n\n\n<p>16, 20, 30, 50, 98, 100 tablets<br><\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p>Sandoz A \/ S, Edvard Thomsens Vej 14, 2300 Copenhagen S, Denmark.<br><\/p>\n","protected":false},"excerpt":{"rendered":"<p> 500 mg, 750 mg film-coated tablets<br \/>\nflucloxacillin<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2206,2200],"tags":[2676,2678,2772,2774,2775,2773,2679,2677,2212,2211],"class_list":["post-8834","post","type-post","status-publish","format-standard","hentry","category-f","category-medicines","tag-flucloxacillin","tag-flucloxacillin-dose","tag-flucloxacillin-sandoz","tag-flucloxacillin-sandoz-dose","tag-flucloxacillin-sandoz-side-effects","tag-flucloxacillin-sandoz-uses","tag-flucloxacillin-side-effects","tag-flucloxacillin-uses","tag-medicine","tag-tablets"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8834","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=8834"}],"version-history":[{"count":6,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8834\/revisions"}],"predecessor-version":[{"id":10017,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8834\/revisions\/10017"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=8834"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=8834"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=8834"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}