{"id":8832,"date":"2021-03-19T10:35:20","date_gmt":"2021-03-19T10:35:20","guid":{"rendered":"https:\/\/zeepedia.com\/?p=8832"},"modified":"2021-04-12T15:11:11","modified_gmt":"2021-04-12T15:11:11","slug":"flucloxacillin-orion","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/flucloxacillin-orion\/","title":{"rendered":"Flucloxacillin Orion &#8211; Flucloxacillin uses, dose and side effects"},"content":{"rendered":"\n<p>\n\n500 mg \/ 750 mg \/ 1g&nbsp;film-coated tablets<br>flucloxacillin<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Flucloxacillin Orion is and what it is used for<\/h2>\n\n\n\n<p>The active substance in Flucloxacillin Orion is flucloxacillin.&nbsp;Flucloxacillin is penicillin&nbsp;(&nbsp;antibiotic&nbsp;) that prevents bacteria from building a normal cell wall.&nbsp;Without a functioning cell wall, the bacteria die quickly.&nbsp;Flucloxacillin Orion is stable against an&nbsp;enzyme&nbsp;(&nbsp;beta-lactamase&nbsp;), which can break down regular&nbsp;penicillin.<br><\/p>\n\n\n\n<p>Flucloxacillin Orion is used for:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>the infection&nbsp;you in the skin and soft tissues<\/li><li>infection&nbsp;of the joints, bones, and lungs (eg&nbsp;pneumonia,&nbsp;chronic&nbsp;bronchitis&nbsp;)<\/li><\/ul>\n\n\n\n<p>Flucloxacillin contained in Flucloxacillin Orion may also be approved for the treatment of other conditions not mentioned in this product information.&nbsp;Ask your doctor, pharmacist, or other healthcare professional if you have any further questions, and always follow their instructions.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you take Flucloxacillin Orion<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not take Flucloxacillin Orion<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to flucloxacillin,&nbsp;penicillin,&nbsp;or any of the other ingredients of this medicine (listed in section 6).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warning and caution<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before taking Flucloxacillin Orion if you:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>is allergic to&nbsp;cephalosporins&nbsp;(&nbsp;antibiotics&nbsp;)<\/li><li>is older<\/li><li>have a liver disease<\/li><li>receive flucloxacillin for a long time<\/li><li>take or will take&nbsp;paracetamol.<\/li><\/ul>\n\n\n\n<p>With concomitant use of flucloxacillin and&nbsp;paracetamol, there is a risk of blood and fluid disturbances (metabolic&nbsp;acidosis&nbsp;due to high anion gap, so-called HAGMA), which occurs when the acidity of blood plasma increases, especially in certain patient groups who are at increased risk, e.g.&nbsp;patients with severe renal impairment, sepsis or malnutrition and especially when using maximum daily doses of&nbsp;paracetamol.&nbsp;HAGMA is a serious condition that requires urgent treatment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Flucloxacillin Orion&nbsp;<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.&nbsp;This is important because some medicines may affect or be affected by treatment with Flucloxacillin Orion.&nbsp;These include, for example:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>certain medicines for&nbsp;tumors&nbsp;and disorders of the immune system (methotrexate)<\/li><li>certain medicines for&nbsp;gout&nbsp;(probenecid)<\/li><li>certain blood thinners (&nbsp;warfarin&nbsp;)<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Flucloxacillin Orion with food, drink, and alcohol<\/h2>\n\n\n\n<p><strong>Flucloxacillin Orion contains&nbsp;sodium.<\/strong><\/p>\n\n\n\n<p>The 500 mg tablets contain 1.2 mmol (28 mg)&nbsp;sodium&nbsp;per tablet, the 750 mg tablets contain 1.8 mmol (42 mg)&nbsp;sodium&nbsp;per tablet and 1 g tablets contain 2.4 mmol (56 mg)&nbsp;sodium&nbsp;per tablet.&nbsp;This should be considered by patients on a low-salt diet.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n<p>If you are pregnant or breast-feeding, think you may be pregnant, or are planning to have a baby, ask your doctor for advice before using this medicine.<br><\/p>\n\n\n\n<p>There are no known risks associated with use during pregnancy.&nbsp;Flucloxacillin passes into breast milk but is unlikely to affect breastfed infants.&nbsp;Your doctor will assess whether you can take Flucloxacillin Orion during pregnancy or while breast-feeding.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>The drug has no or negligible effect on the ability to drive or use machines.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.&nbsp;One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or&nbsp;side effects.<\/p>\n\n\n\n<p>Descriptions of these effects and&nbsp;side effects&nbsp;can be found in other sections.&nbsp;Read all the information in this leaflet for guidance.&nbsp;If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Flucloxacillin Orion contains excipients<\/h2>\n\n\n\n<p>The 500 mg tablets contain 1.2 mmol (28 mg)&nbsp;sodium&nbsp;per tablet, the 750 mg tablets contain 1.8 mmol (42 mg)&nbsp;sodium&nbsp;per tablet and 1 g tablets contain 2.4 mmol (56 mg)&nbsp;sodium&nbsp;per tablet.&nbsp;This should be considered by patients on a low-salt diet.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to take Flucloxacillin Orion<\/h2>\n\n\n\n<p>Always take this medicine exactly as your doctor has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.&nbsp;Your doctor will decide on a&nbsp;dose&nbsp;to suit you.<br><\/p>\n\n\n\n<p>Take the tablets between meals to get the best effect from Flucloxacillin Orion.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you take more Flucloxacillin Orion then you should<\/h2>\n\n\n\n<p>If you have ingested too much medicine or if e.g.&nbsp;if a child has accidentally ingested the medicine, contact a doctor, hospital, or the Poison Information Center for risk assessment and advice<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Flucloxacillin Orion<\/h2>\n\n\n\n<p>If you forget to take a&nbsp;dose, take it as soon as you remember.&nbsp;Do not take a double&nbsp;dose&nbsp;to make up for a forgotten&nbsp;dose.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop taking Flucloxacillin Orion<\/h2>\n\n\n\n<p>Even if you feel better after a few days, you must complete the entire course of Flucloxacillin Orion as&nbsp;prescribed.&nbsp;Otherwise, some bacteria may survive, grow in numbers and cause a new outbreak of&nbsp;infection&nbsp;one.<br><\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects, although not everybody gets them.<\/p>\n\n\n\n<p>Stop taking Flucloxacillin Orion and contact your doctor immediately if you experience any of the following symptoms of rare&nbsp;side effects&nbsp;(may affect up to 1 in 1,000 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Symptoms of a severe&nbsp;allergic reaction, such as swelling of the face, tongue, or throat, difficulty swallowing,&nbsp;hives,&nbsp;and difficulty breathing<\/li><li>Severe diarrhea, usually with blood or mucus, stomach pain, and fever (pseudomembranous&nbsp;colitis&nbsp;)<\/li><li>Decreased number of&nbsp;white blood cells&nbsp;(&nbsp;agranulocytosis&nbsp;or&nbsp;neutropenia&nbsp;) that cause fever and severe deterioration of your general condition or fever with local symptoms of infection, such as sore throat or mouth or difficulty urinating<\/li><li>Signs of liver damage or diseases, such as darker urine or paler stools, yellowing of the skin, or whites of the eyes (jaundice)<\/li><li>Sudden onset and severe rash, which may include blistering or peeling of the skin and mucous membranes (erythema multiforme,&nbsp;Stevens-Johnson syndrome,&nbsp;or&nbsp;toxic epidermal necrolysis&nbsp;).&nbsp;In severe reactions, fever, sores on the surface of the eye, and joint pain can also occur.<\/li><\/ul>\n\n\n\n<p><br><em>Common&nbsp;&nbsp;<\/em><em>(may affect up to 1 in 10 people)<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Nausea or diarrhea<\/li><li>Rash.<\/li><\/ul>\n\n\n\n<p><em>Uncommon&nbsp;<\/em>&nbsp;<em>(may affect up to 1 in 100 people)<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>A large number of a certain type of&nbsp;white blood cell&nbsp;(&nbsp;eosinophilia&nbsp;)<\/li><li>Hives<\/li><\/ul>\n\n\n\n<p><em>Very rare (&nbsp;<\/em><em>may affect up to 1&nbsp;<\/em><em>in 10,000 people)<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Itching<\/li><\/ul>\n\n\n\n<p>Very rare cases of blood and fluid disturbances (metabolic&nbsp;acidosis&nbsp;due to high anion gap), which occur when the acidity of blood plasma increases, with concomitant use of flucloxacillin and&nbsp;paracetamol, usually in patients with risk factors (see section 2).<br><\/p>\n\n\n\n<p><em>Has been reported (&nbsp;<\/em><em>occurs in an unknown number of users)<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Dizziness<\/li><li>Stomach ache, vomiting<\/li><li>Serious skin side effects<ul><li>Red, scaly rash with bumps under the skin and blisters (exanthematous&nbsp;pustulosis&nbsp;).&nbsp;Contact a doctor immediately if you get any of these symptoms.<\/li><\/ul><\/li><\/ul>\n\n\n\n<p>Itching&nbsp;in the abdomen can be caused by fungal overgrowth.&nbsp;White coating in the mouth, especially on the tongue can also be caused by a fungal infection.<br><\/p>\n\n\n\n<p><strong>Reporting of&nbsp;side effects&nbsp;ar<\/strong><\/p>\n\n\n\n<p>If you get&nbsp;any side effects, talk to your doctor or pharmacist.&nbsp;This also applies to any&nbsp;side effects&nbsp;not mentioned in this information.&nbsp;You can also report&nbsp;side effects&nbsp;directly (see details below).&nbsp;By reporting&nbsp;side effects, you can help increase drug safety information.<\/p>\n\n\n\n<p>The Medical Products Agency,<\/p>\n\n\n\n<p>Box 26,<\/p>\n\n\n\n<p>SE-751 03 Uppsala.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Flucloxacillin Orion<\/h2>\n\n\n\n<p>No special storage instructions.<br><\/p>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<br><\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton and can after EXP.&nbsp;The expiration date is the last day of the specified month.<br><\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is flucloxacillin 1 tablet contains flucloxacillin sodium monohydrate equivalent to 500 mg, 750 mg, or 1 g flucloxacillin.<\/li><li>Other ingredients are tablet<em> core:<\/em>&nbsp;Magnesium stearate, povidone, croscarmellose sodium, microcrystalline cellulose. <em>Film coating:<\/em>&nbsp;Titanium dioxide, macrogols, easily flowing paraffin, hypromellose.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>Film-coated tablet (tablet).<br><\/p>\n\n\n\n<p><strong>500 mg:<\/strong>&nbsp;White to off-white, capsule-shaped, film-coated biconvex tablet, marked &#8220;Y&#8221; on one side and &#8217;05 &#8216;with a notch between &#8220;0&#8221; and &#8220;5&#8221; on the other side, 17.4 x 8.1 mm.&nbsp;The tablet can be divided into two equal&nbsp;doses.<br><\/p>\n\n\n\n<p><strong>750 mg:<\/strong>&nbsp;White to off-white, capsule-shaped, film-coated biconvex tablet, marked &#8220;Y&#8221; on one side and &#8217;06&#8217; with a notch between &#8220;0&#8221; and &#8220;6&#8221; on the other side, 20.4 x 8.4 mm.&nbsp;The tablet can be divided into two equal&nbsp;doses.<br><\/p>\n\n\n\n<p><strong>1 g:<\/strong>&nbsp;&nbsp;White to off-white, oval, film-coated biconvex tablet, marked with &#8216;T&#8217; on one side and &#8217;63&#8217; with a notch between &#8216;6&#8217; and &#8216;3&#8217; on the other side, 9.8 x 21.3 mm.&nbsp;The tablet can be divided into two equal&nbsp;doses.<br><\/p>\n\n\n\n<p><strong>Pack sizes:<\/strong><\/p>\n\n\n\n<p>500 mg: 30, 50, and 100 tablets in a plastic jar<\/p>\n\n\n\n<p>750 mg: 20, 30, 50, and 100 tablets in a plastic jar<\/p>\n\n\n\n<p>1 g: 21, 30, 50, and 75 tablets in a plastic jar.<\/p>\n\n\n\n<p>The jar contains a desiccant.<br><\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p>Orion Corporation<\/p>\n\n\n\n<p>Orionv\u00e4gen 1<\/p>\n\n\n\n<p>FI-02200 Espoo<\/p>\n\n\n\n<p>Finland<br><\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Orion Corporation Orion Pharma<\/p>\n\n\n\n<p>Orionv\u00e4gen 1<\/p>\n\n\n\n<p>FI-02200 Espoo<\/p>\n\n\n\n<p>Finland<\/p>\n\n\n\n<p>For further information about this medicine, contact your local Marketing Authorization Holder.<br><\/p>\n\n\n\n<p>Orion Pharma AB<\/p>\n\n\n\n<p>medinfo@orionpharma.com<\/p>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p> 500 mg \/ 750 mg \/ 1g film-coated tablets<br \/>\nflucloxacillin<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2206,2200],"tags":[2676,2678,2776,2778,2779,2777,2679,2677,2212,2211],"class_list":["post-8832","post","type-post","status-publish","format-standard","hentry","category-f","category-medicines","tag-flucloxacillin","tag-flucloxacillin-dose","tag-flucloxacillin-orion","tag-flucloxacillin-orion-dose","tag-flucloxacillin-orion-side-effects","tag-flucloxacillin-orion-uses","tag-flucloxacillin-side-effects","tag-flucloxacillin-uses","tag-medicine","tag-tablets"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8832","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=8832"}],"version-history":[{"count":5,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8832\/revisions"}],"predecessor-version":[{"id":10021,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8832\/revisions\/10021"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=8832"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=8832"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=8832"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}