{"id":8748,"date":"2021-03-18T10:58:13","date_gmt":"2021-03-18T10:58:13","guid":{"rendered":"https:\/\/zeepedia.com\/?p=8748"},"modified":"2021-04-12T14:52:28","modified_gmt":"2021-04-12T14:52:28","slug":"ferinject","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/ferinject\/","title":{"rendered":"Ferinject &#8211; Iron Carboxymaltose uses, dose and side effects"},"content":{"rendered":"\n<p>\n\n50 mg Iron \/ ml&nbsp;Solution for injection \/ infusion.&nbsp;<br>iron carboxymaltose<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What Ferinject is and what it is used for<\/h2>\n\n\n\n<p>Ferinject is a medicine that contains iron.<br><\/p>\n\n\n\n<p>Medicines that contain iron are used when you do not have enough iron in your body.&nbsp;This is called an iron deficiency.<br><\/p>\n\n\n\n<p>Ferinject is used to treat iron deficiency when:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>iron given by mouth is not enough.<\/li><li>you do not tolerate iron given by mouth.<\/li><li>Your doctor decides that you need iron very quickly to replenish your iron stores.<\/li><\/ul>\n\n\n\n<p>Your doctor will determine if you have an iron deficiency by performing a blood test.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2. What you need to know before you receive Ferinject<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Ferinject must not be given to you<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic (hypersensitive) to iron carboxymaltose or any of the other ingredients of this medicine (listed in section 6).<\/li><li>if you have had severe allergic reactions to other injectable iron preparations.<\/li><li>if you have&nbsp;anemia&nbsp;that is&nbsp;<em>not<\/em>&nbsp;due to iron deficiency,<\/li><li>if you have too much iron in your body or if the iron is not used properly,<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor or nurse before giving Ferinject:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have previously been allergic to medicines.<\/li><li>if you have systemic lupus erythematosus.<\/li><li>if you have&nbsp;rheumatoid arthritis.<\/li><li>if you have severe&nbsp;asthma,&nbsp;eczema,&nbsp;or other&nbsp;allergies.<\/li><li>if you have an&nbsp;infection.<\/li><li>if you have liver problems.<\/li><li>if you have or have had low levels of phosphate in your blood.<\/li><\/ul>\n\n\n\n<p>Ferinject should not be given to children under 14 years of age.<\/p>\n\n\n\n<p>Improper&nbsp;administration&nbsp;of Ferinject may cause leakage of the product at the site of administration, which may lead to skin irritation or possible prolonged brown discoloration at the site of administration.&nbsp;The administration&nbsp;must be stopped immediately when this occurs.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Ferinject<\/h2>\n\n\n\n<p>Tell your doctor if you are taking, have recently taken, or might take any other medicines, including medicines obtained without a prescription.&nbsp;If Ferinject is given together with oral iron preparations, the effect of the oral preparations may be impaired.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy<\/h2>\n\n\n\n<p>There are limited data from the use of Ferinject in pregnant women.&nbsp;It is important that you tell your doctor if you are pregnant, think you may be pregnant, or are planning to have a baby.<\/p>\n\n\n\n<p>If you become pregnant during treatment, you must consult your doctor.&nbsp;Your doctor will decide if you should receive this medicine or not.<br><\/p>\n\n\n\n<p><strong>Breast-feeding<\/strong><\/p>\n\n\n\n<p>If you are breast-feeding, talk to your doctor before giving Ferinject.<\/p>\n\n\n\n<p>It is unlikely that Ferinject poses a risk to the breast-fed baby.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Ferinject is unlikely to affect your ability to drive or use machines.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Important information about some of the ingredients of Ferinject<\/h2>\n\n\n\n<p>This medicine contains 0.24 mmol (or 5.5 mg)&nbsp;sodium&nbsp;per milliliter of undiluted solution.&nbsp;This should be considered by patients prescribed a low-salt diet.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. How to get Ferinject<\/h2>\n\n\n\n<p>Your doctor will decide how much Ferinject is given to you, how often you need it, and for how long.&nbsp;Your doctor will take a blood test to determine the&nbsp;dose&nbsp;you need.&nbsp;Your doctor or nurse will administer Ferinject undiluted by&nbsp;injection,&nbsp;dialysis, or diluted by infusion:<br><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>As an&nbsp;injection, you can receive up to 20 ml of Ferinject, equivalent to 1,000 mg of iron, once a week, directly into a vein.<\/li><li>If you are undergoing&nbsp;dialysis, you can get Ferinject during&nbsp;hemodialysis&nbsp;via the dialysis machine.<\/li><li>As&nbsp;an infusion, you can receive up to 20 ml of Ferinject, equivalent to 1,000 mg of iron, once a week directly into a vein.<\/li><li>For&nbsp;infusion,&nbsp;Ferinject is diluted with sodium chloride solution and the amount can therefore amount to 250 ml and look like a brown solution.<\/li><\/ul>\n\n\n\n<p>Ferinject is administered in an environment where appropriate and prompt care can be given for immune allergic reactions.&nbsp;You will be observed for at least 30 minutes by your doctor or nurse after each&nbsp;administration.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you take more Ferinject than you should<\/h2>\n\n\n\n<p>As this medicine is given to you by trained healthcare professionals, it is unlikely that you will be given too much of this medicine.<\/p>\n\n\n\n<p>An overdose can cause an accumulation of iron in your body.&nbsp;Doctors will monitor for signs of too much iron to avoid iron buildup.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects,&nbsp;although not everybody gets them.<br><\/p>\n\n\n\n<p><strong><em>Serious side effects:<\/em><\/strong><\/p>\n\n\n\n<p>Talk to your doctor immediately if you experience any of the following signs and symptoms that may indicate a severe allergic reaction: skin rash (eg,&nbsp;hives&nbsp;),&nbsp;itching, difficulty breathing, wheezing or wheezing, and\/or swelling of the lips, tongue, pharynx or body and chest pain, which may be a sign of a potentially serious&nbsp;allergic reaction&nbsp;called Kuoni&#8217;s syndrome.<br><\/p>\n\n\n\n<p>In some patients, these allergic reactions (which occur in less than 1 in 1,000 users) can be severe or life-threatening (so-called anaphylactoid\/anaphylactic reactions) and may be associated with cardiovascular problems and loss of consciousness.<br><\/p>\n\n\n\n<p>Tell your doctor if you experience increasing fatigue, muscle or skeletal pain (pain in arms or legs, joints or back).&nbsp;These symptoms can be a sign of a decrease in phosphorus in the blood, which can lead to your bone becoming soft (osteomalacia).&nbsp;This condition can sometimes lead to bone fractures.&nbsp;Your doctor may also check your blood phosphate levels, especially if you need several iron treatments over time.<br><\/p>\n\n\n\n<p>Your doctor is aware of these possible&nbsp;side effects&nbsp;and will monitor you during and after you receive Ferinject.<br><\/p>\n\n\n\n<p><strong><em>Other&nbsp;side effects&nbsp;that you should talk to your doctor about if they become serious:<\/em><\/strong><\/p>\n\n\n\n<p><strong>Common<\/strong>&nbsp;(may affect up to 1 in 10 people): headache, dizziness, feeling hot (swelling), high&nbsp;blood pressure, nausea, and reactions at the injection\/infusion site (see also section 2).<br><\/p>\n\n\n\n<p><strong>Uncommon<\/strong>&nbsp;(may affect up to 1 in 100 people): numbness, tingling or stinging sensation in the skin, taste disturbances, high&nbsp;heart rate, low&nbsp;blood pressure, difficulty breathing, vomiting, indigestion, stomach pain, constipation, diarrhea,&nbsp;itching, hives, redness of the skin, skin rash, muscle aches, joint and\/or back pain, pain in arms or legs, muscle cramps, fever, fatigue, chest pain, swelling of hands and\/or feet, and chills.<br><\/p>\n\n\n\n<p><strong>Rare<\/strong>&nbsp;(may affect up to 1 in 1,000 people):&nbsp;inflammation&nbsp;of a vein, a general feeling of discomfort, anxiety, fainting, weakness, tingling, flatulence, rapid swelling of the face, mouth, tongue, or throat which may cause difficulty breathing and paleness.<br><\/p>\n\n\n\n<p><strong>No known frequency<\/strong>&nbsp;(can not be calculated from the available data): loss of consciousness and swelling of the face.<br><\/p>\n\n\n\n<p>Influenza-like illness (which may affect up to 1 in 1,000 people) can occur for a few hours up to several days after&nbsp;injection&nbsp;and is usually characterized by symptoms such as high temperature, and aches and pains in muscles and joints.<br><\/p>\n\n\n\n<p>Some blood parameters (values) can be changed temporarily, which can be detected during laboratory tests.<\/p>\n\n\n\n<p>The following change in blood parameters is common: decrease in phosphorus in the blood.<\/p>\n\n\n\n<p>The following changes in blood parameters are less common: an increase in certain liver enzymes called alanine aminotransferase,&nbsp;aspartate aminotransferase, gamma-glutamyltransferase, and alkaline phosphatase, and an increase in an&nbsp;enzyme&nbsp;called&nbsp;lactate dehydrogenase.<br><\/p>\n\n\n\n<p>Ask your doctor for more information.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Ferinject<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<br><\/p>\n\n\n\n<p>Ferinject is used before the expiry date which is stated on the label.&nbsp;The expiration date is the last day of the specified month.<br><\/p>\n\n\n\n<p>Store in the original package.&nbsp;Sensitive to light.&nbsp;Do not store above 30 \u00b0 C.&nbsp;Do not freeze.<\/p>\n\n\n\n<p>Once a&nbsp;vial&nbsp;of Ferinject has been opened, it should be used immediately.&nbsp;After dilution with sodium chloride solution, the diluted solution should be used immediately.<br><\/p>\n\n\n\n<p>Ferinject is usually stored by your doctor or hospital.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<p>The active substance is iron (in the form of iron carboxymaltose, an iron carbohydrate composition).&nbsp;The concentration of iron in the medicine is 50 mg per milliliter.&nbsp;The other ingredients are sodium hydroxide (for&nbsp;pH&nbsp;adjustment&nbsp;),&nbsp;hydrochloric acid&nbsp;(for&nbsp;pH&nbsp;adjustment&nbsp;), and water for injections.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>Ferinject is a dark brown, opaque solution for injection\/infusion.<br><\/p>\n\n\n\n<p>Ferinject is delivered in glass bottles that contain:<br><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>2 ml of solution corresponds to 100 mg of iron.&nbsp;Available in pack sizes of 1, 2, and 5 bottles<\/li><li>10 ml of solution corresponds to 500 mg of iron.&nbsp;Available in pack sizes of 1, 2, and 5 bottles<\/li><li>20 ml of solution corresponds to 1,000 mg of iron.&nbsp;Available in a pack size of 1 bottle.<\/li><\/ul>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p>Vifor France&nbsp;<br>100-101 Terrace Boieldieu<\/p>\n\n\n\n<p>Franklin La D\u00e9fense Tour 8<\/p>\n\n\n\n<p>92042 Paris La D\u00e9fense Cedex<\/p>\n\n\n\n<p>France&nbsp;<br>Tel: +33 (0) 1 41 06 58 90&nbsp;<br>Fax: +33 (0) 1 41 06 58 99&nbsp;<br>e-mail: contact-fr@viforpharma.com<br><\/p>\n\n\n\n<p><strong>This medicinal product is authorized under the European Economic Area under the following names&nbsp;<\/strong><strong>:<\/strong><\/p>\n\n\n\n<p>Bulgaria, Cyprus, Denmark, Estonia, Finland, France, Greece, Ireland, Iceland, Italy, Croatia, Latvia, Netherlands, Norway, Poland, Portugal, Romania, Slovakia, Spain, UK, Czech Republic, Germany, Hungary Austria: Ferinject .<\/p>\n\n\n\n<p>Belgium, Luxembourg: Injectafer.&nbsp;Slovenia: Iroprem<br><\/p>\n","protected":false},"excerpt":{"rendered":"<p> 50 mg Iron \/ ml Solution for injection \/ infusion.<br \/>\niron carboxymaltose<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2206,2200],"tags":[2965,2967,2968,2966,2215,2962,2963,2964,2961,2212],"class_list":["post-8748","post","type-post","status-publish","format-standard","hentry","category-f","category-medicines","tag-ferinject","tag-ferinject-dose","tag-ferinject-side-effects","tag-ferinject-uses","tag-injection","tag-iron-carboxymaltose","tag-iron-carboxymaltose-dose","tag-iron-carboxymaltose-side-effects","tag-iron-carboxymaltose-uses","tag-medicine"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8748","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=8748"}],"version-history":[{"count":5,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8748\/revisions"}],"predecessor-version":[{"id":9978,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8748\/revisions\/9978"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=8748"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=8748"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=8748"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}