{"id":8710,"date":"2021-03-17T07:49:08","date_gmt":"2021-03-17T07:49:08","guid":{"rendered":"https:\/\/zeepedia.com\/?p=8710"},"modified":"2021-04-12T14:55:44","modified_gmt":"2021-04-12T14:55:44","slug":"fenylefrin-unimedic","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/fenylefrin-unimedic\/","title":{"rendered":"Fenylefrin Unimedic &#8211; Phenylephrine uses, dose and side effects"},"content":{"rendered":"\n<p>\n\n0.05 mg \/ ml and 0.1 mg \/ ml&nbsp;injection&nbsp;solution&nbsp;<br>phenylephrine<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Phenylephrine Unimedic is and what it is used for<\/h2>\n\n\n\n<p>This drug belongs to a group called adrenergic or dopaminergic drugs.&nbsp;PhenylephrineUnimedic is used to treat low&nbsp;blood pressure&nbsp;that can occur with different types of anesthesia.<br><\/p>\n\n\n\n<p>Phenylephrine contained&nbsp;in&nbsp;Phenylephrine&nbsp;Unimedic may also be approved for the treatment of other conditions not mentioned in this product information.&nbsp;Ask your doctor, pharmacist, or other healthcare professional if you have any further questions, and always follow their instructions.<\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you use Fenylefrin Unimedic<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Phenylephrine Unimedic<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to&nbsp;phenylephrine&nbsp;or any of the other ingredients of this medicine (listed in section 6).<\/li><li>if you suffer from&nbsp;hypertension&nbsp;(high&nbsp;blood pressure&nbsp;)<\/li><li>if you suffer from&nbsp;peripheral&nbsp;vascular&nbsp;disease (poor blood circulation)<\/li><li>if you are taking a non-selective&nbsp;monoxide inhibitor (MAO) for the treatment of depression (iproniazid, nialamide), or within 2 weeks after stopping that treatment<\/li><li>if you suffer from severe&nbsp;toxic goiter&nbsp;(overactive&nbsp;thyroid gland&nbsp;)<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor, pharmacist, or nurse before&nbsp;taking&nbsp;Fenylefrin Unimedic.<br><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are older<\/li><li>if you have an overactive&nbsp;thyroid gland<\/li><li>if you suffer from heart problems such as low&nbsp;heart rate, heart block (partial), heart muscle disease, poor blood circulation in the heart, impaired blood circulation in the legs, unregulated heart rhythm,&nbsp;tachycardia&nbsp;(fast heartbeat),&nbsp;bradycardia&nbsp;(slow heartbeat), angina<\/li><li>if you have poor blood circulation in the brain<\/li><li>if you have atherosclerosis (hardening and thickening of the walls of blood vessels)<\/li><li>if you have&nbsp;diabetes mellitus<\/li><li>if you are being treated with&nbsp;oxytocin&nbsp;as the effect on&nbsp;vessels&nbsp;can be exacerbated and cause greatly increased&nbsp;blood pressure&nbsp;and&nbsp;stroke&nbsp;during the period immediately after delivery<\/li><li>if you suffer from high&nbsp;blood pressure&nbsp;in the&nbsp;artery&nbsp;are<\/li><li>if you have narrow-angle glaucoma (&nbsp;glaucoma&nbsp;)<\/li><\/ul>\n\n\n\n<p>Patients with severe&nbsp;heart failure&nbsp;may be worsened by treatment with&nbsp;phenylephrinedue to narrowing of blood vessels.<\/p>\n\n\n\n<p>The blood pressure&nbsp;in your&nbsp;arteries&nbsp;will be during treatment.&nbsp;If you have heart disease, the function of important organs will also be monitored.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>It is not recommended for use in children due to insufficient data on efficacy, safety, and dosage recommendations.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Phenylephrine Unimedic<\/h2>\n\n\n\n<p>Tell your doctor, pharmacist, or nurse if you are taking, have recently taken, or might take any other medicines.<br><\/p>\n\n\n\n<p>Do not&nbsp;use&nbsp;Phenylephrine Unimedic with:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>iproniazid, nialamide (for depression)<\/li><\/ul>\n\n\n\n<p>The following medicines may affect or be affected by concomitant use:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>dihydroergotamine,&nbsp;ergotamine&nbsp;, methylergometrine, methysergide (for&nbsp;migraine)<\/li><li>linezolid (&nbsp;antibiotics&nbsp;)<\/li><li>bromocriptine, cabergoline, lisuride, pergolide (for&nbsp;Parkinson&#8217;s disease&nbsp;)<\/li><li>desipramine, imipramine, nortriptyline, moclobemide, toloxatone,&nbsp;venlafaxine&nbsp;(for depression)<\/li><li>inhaled anesthetics (desflurane, enflurane, halothane, isoflurane, methoxyflurane, sevoflurane)<\/li><li>drug for the treatment of high&nbsp;blood pressure&nbsp;(guanethidine)<\/li><li>drugs for the treatment of&nbsp;heart failure&nbsp;and certain irregular heartbeats (cardiac glycosides)<\/li><li>drugs for the treatment of abnormal heart rhythm (&nbsp;quinidine&nbsp;)<\/li><li>medicines used in childbirth (&nbsp;oxytocin&nbsp;)<\/li><\/ul>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n<p>If you are pregnant or breast-feeding, think you may be pregnant, or are planning to have a baby, ask your doctor for advice before taking this medicine.<br><\/p>\n\n\n\n<p>Pregnancy<\/p>\n\n\n\n<p>This medicine should not be used during pregnancy unless clearly necessary.<br><\/p>\n\n\n\n<p>Breast-feeding<\/p>\n\n\n\n<p>This medicine should not be used during breast-feeding unless clearly necessary.&nbsp;However, if you receive this only once during childbirth, breastfeeding is possible.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Not relevant.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Phenylephrine Unimedic contains excipients<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>One 10 ml&nbsp;ampoule&nbsp;of&nbsp;Phenylephrine&nbsp;Unimedic contains 1.6 mmol (36.8 mg)&nbsp;sodium&nbsp;per&nbsp;dose.&nbsp;This should be considered by patients on a low-salt diet.<\/li><li>One 5 ml contains 0.8 mmol (18.4 mg)&nbsp;sodium&nbsp;per&nbsp;dose, ie&nbsp;it contains less than 1 mmol&nbsp;sodium&nbsp;(23 mg) per&nbsp;dose, which means it is essentially &#8216;sodium-free&#8217;.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">3. How to use Phenylephrine Unimedic<\/h2>\n\n\n\n<p>The drug will be given by healthcare professionals with appropriate training and experience.<br><\/p>\n\n\n\n<p><strong>Adults<\/strong><\/p>\n\n\n\n<p>Your doctor or nurse will give you&nbsp;Phenylephrine&nbsp;Unimedic in a vein (&nbsp;intravenously&nbsp;).&nbsp;Your doctor will decide the right&nbsp;dose&nbsp;for you and when and how to&nbsp;inject&nbsp;one.<br><\/p>\n\n\n\n<p><strong>Patients with renal impairment<\/strong><\/p>\n\n\n\n<p>Patients with renal impairment may need lower&nbsp;doses&nbsp;of&nbsp;phenylephrine.<br><\/p>\n\n\n\n<p><strong>Patients with hepatic impairment<\/strong><\/p>\n\n\n\n<p>Patients with hepatic impairment may need higher&nbsp;doses&nbsp;of&nbsp;phenylephrine.<br><\/p>\n\n\n\n<p><strong>Elderly Elderly<\/strong>&nbsp;<br>people should be treated with caution.<br><\/p>\n\n\n\n<p><strong>Children<\/strong><\/p>\n\n\n\n<p>It is not recommended for use in children due to insufficient data on efficacy, safety, and dosage recommendations.&nbsp;<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you use more Phenylefrin Unimedic then you should&nbsp;<\/h2>\n\n\n\n<p>If you have ingested too much medicine, contact your doctor, hospital, or the Poison Information Center for risk assessment and advice.<br><\/p>\n\n\n\n<p>Signs that you have been given too much&nbsp;Phenylephrine&nbsp;Unimedic are faster and irregular heartbeats, headaches, nausea, vomiting,&nbsp;psychosis, hallucinations, and high&nbsp;blood pressure.<\/p>\n\n\n\n<p>This is unlikely to happen because you are receiving the medicine in a hospital.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects, although not everybody gets them.<br><\/p>\n\n\n\n<p>The following&nbsp;side effects&nbsp;have been reported:<\/p>\n\n\n\n<p>Some&nbsp;side effects&nbsp;can be serious.&nbsp;Tell your doctor immediately if you get any of the following:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>chest pain or pain due to angina<\/li><li>irregular heartbeats<\/li><li>a feeling that the heart is beating hard in the chest<\/li><li>cerebral hemorrhage (speech difficulties, dizziness, paralysis on one side of the body)<\/li><li>psychosis&nbsp;(loses contact with reality)<\/li><\/ul>\n\n\n\n<p>Other&nbsp;side effects&nbsp;that have been reported (unknown frequency)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>hypersensitivity reaction<\/li><li>excessive&nbsp;pupil&nbsp;s<\/li><li>increased pressure in the eye (worsening of&nbsp;glaucoma&nbsp;)<\/li><li>anxiety (restlessness)<\/li><li>anxiety<\/li><li>confusion<\/li><li>headache<\/li><li>nervousness<\/li><li>difficulty sleeping (difficulty falling asleep or sleeping)<\/li><li>shaking (&nbsp;tremor&nbsp;)<\/li><li>burning sensation on the skin<\/li><li>an ant crawls in the skin<\/li><li>itching&nbsp;or tingling on the skin (paresthesia)<\/li><li>slow or fast heartbeats<\/li><li>high&nbsp;blood pressure<\/li><li>difficulty breathing<\/li><li>fluid in the lung (s)<\/li><li>nausea<\/li><li>vomiting<\/li><li>sweating<\/li><li>pallor, pale color of the skin<\/li><li>goosebumps<\/li><li>tissue damage at the injection site<\/li><li>muscle weakness<\/li><li>difficulty urinating or total urinary retention<\/li><\/ul>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Phenylephrine Unimedic<\/h2>\n\n\n\n<p>Store in the original package.&nbsp;Sensitive to light.<br><\/p>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<br><\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton after &#8216;EXP&#8217;.&nbsp;The expiration date is the last day of the specified month.<br><\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is&nbsp;phenylephrine&nbsp;as phenylephrine hydrochloride 0.05 mg \/ ml and 0.1 mg \/ ml respectively.<\/li><li>The other ingredients are sodium chloride, sodium citrate, citric acid, water for injections,&nbsp;hydrochloric acid,&nbsp;and sodium hydroxide for&nbsp;pH&nbsp;adjustment.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>Clear, colorless solution.<br><\/p>\n\n\n\n<p>Phenylephrine&nbsp;Unimedic 0.05 mg\/ml,&nbsp;solution for injection is&nbsp;supplied in&nbsp;a 10 ml&nbsp;glass ampoule.<\/p>\n\n\n\n<p>Phenylephrine&nbsp;Unimedic 0.1 mg\/ml,&nbsp;solution for injection is&nbsp;supplied in&nbsp;5 ml and 10 ml&nbsp;glass&nbsp;ampoules.<br><\/p>\n\n\n\n<p>The ampoules&nbsp;are packed in plastic trays in cartons of 5, 10, 20, 50, and 100&nbsp;ampoules.<br><\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p>Unimedic Pharma AB<\/p>\n\n\n\n<p>Box 6216,<\/p>\n\n\n\n<p>102 34<\/p>\n\n\n\n<p>Stockholm<\/p>\n\n\n\n<p>Email:&nbsp;medinfo@unimedicpharma.se<\/p>\n\n\n\n<p>Tel: +46 (0) 10 130 99 50<br><\/p>\n\n\n\n<p><strong>For any information about this medicine, please see the Marketing Authorization Holder.<\/strong><br><\/p>\n\n\n\n<p><em>Manufacturer<\/em><\/p>\n\n\n\n<p>Unimedic AB<\/p>\n\n\n\n<p>Storjordenv\u00e4gen 2<\/p>\n\n\n\n<p>SE \u2011 864 31 Matfors<br><\/p>\n","protected":false},"excerpt":{"rendered":"<p> 0.05 mg \/ ml and 0.1 mg \/ ml injection solution<br \/>\nphenylephrine<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2206,2200],"tags":[3013,3015,3016,3014,2215,2212,2997,2999,3000,2998],"class_list":["post-8710","post","type-post","status-publish","format-standard","hentry","category-f","category-medicines","tag-fenylefrin-unimedic","tag-fenylefrin-unimedic-dose","tag-fenylefrin-unimedic-side-effects","tag-fenylefrin-unimedic-uses","tag-injection","tag-medicine","tag-phenylephrine","tag-phenylephrine-dose","tag-phenylephrine-side-effects","tag-phenylephrine-uses"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8710","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=8710"}],"version-history":[{"count":5,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8710\/revisions"}],"predecessor-version":[{"id":9985,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8710\/revisions\/9985"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=8710"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=8710"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=8710"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}