{"id":8681,"date":"2021-03-17T07:21:02","date_gmt":"2021-03-17T07:21:02","guid":{"rendered":"https:\/\/zeepedia.com\/?p=8681"},"modified":"2021-04-08T18:59:02","modified_gmt":"2021-04-08T18:59:02","slug":"fenantoin-rph-pharma","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/fenantoin-rph-pharma\/","title":{"rendered":"Fenantoin RPH Pharma &#8211; Phenytoin uses, dose, and side effects"},"content":{"rendered":"\n<p>\n\n100 mg&nbsp;tablets&nbsp;<br>phenytoin<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What Fenantoin RPH Pharma is and what it is used for<\/h2>\n\n\n\n<p>Fenantoin RPH Pharma contains phenytoin which counteracts seizures and shortens seizures that occur by limiting the spread of irritation to the brain.<\/p>\n\n\n\n<p>Fenantoin RPH Pharma is used for&nbsp;epilepsy, in so-called generalized tonic-clonic epileptic seizures (&nbsp;grand mal&nbsp;), and for seizures where only parts of the brain are affected (&nbsp;partial seizures&nbsp;).<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before using Fenantoin RPH Pharma&nbsp;<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Fenantoin RPH Pharma&nbsp;<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have a disease that involves the formation of porphyrins in the liver (&nbsp;acute intermittent&nbsp;porphyria&nbsp;).<\/li><li>if you are allergic to&nbsp;phenytoin&nbsp;or any of the other ingredients of this medicine (listed in section 6).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before using Fenantoin RPH Pharma.<br><\/p>\n\n\n\n<p>Skin reactions, which may be life-threatening (&nbsp;Stevens-Johnson syndrome&nbsp;and&nbsp;toxic epidermal necrolysis&nbsp;), have been reported with the use of Fenantoin.&nbsp;It can start as red-violet target-like or round spots with blistering in the middle, often symmetrically spread, on the torso.<br><\/p>\n\n\n\n<p>Additional signs to be aware of are sores in the mouth, throat, nose, genitals, or eye inflammation (red and swollen eyes).<\/p>\n\n\n\n<p>The skin reactions, which can be life-threatening, are often followed by&nbsp;flu-like symptoms.&nbsp;The rash can develop into blisters over large areas of skin detachment.<\/p>\n\n\n\n<p>The risk of serious skin reactions is greatest during the first weeks of treatment.<\/p>\n\n\n\n<p>If you have had&nbsp;Stevens-Johnson&nbsp;syndrome or&nbsp;toxic epidermal necrolysis&nbsp;while using Fenantoin, you must never use Fenantoin again.<\/p>\n\n\n\n<p>If you get a rash or signs of these skin reactions, contact your doctor immediately and tell them you are taking this medicine.&nbsp;If you stop taking Fenantoin RPH Pharma too quickly, there is a risk of an increased number and possibly more severe seizures.&nbsp;If the medical treatment is to be terminated, it is therefore very important that the phasing out takes place slowly, often over the course of 3-12 months.&nbsp;However, never change your treatment yourself without consulting a doctor.<br><\/p>\n\n\n\n<p>Those with hepatic or renal impairment should consult a physician before starting treatment with Fenantoin RPH Pharma.<\/p>\n\n\n\n<p>Fenantoin RPH Pharma can in rare cases affect the white&nbsp;blood cells&nbsp;so that the&nbsp;defense against&nbsp;infection deteriorates.&nbsp;Therefore, contact your doctor if you get a sudden fever, sore throat, and\/or sore mouth.<\/p>\n\n\n\n<p>Thorough cleaning of the teeth with fluoride toothpaste twice daily is essential to counteract swelling of the gums and tooth damage.<\/p>\n\n\n\n<p>If you get a rash, fever, joint pain, jaundice (whites of the eyes and skin turn yellow), enlarged&nbsp;lymph nodes, you should contact a doctor as soon as possible.&nbsp;This may be a sign of hypersensitivity syndrome.<\/p>\n\n\n\n<p>A small number of people who are treated with antiepileptic&nbsp;drugs&nbsp;such as&nbsp;phenytoin have also had thoughts of harming themselves or committing suicide.&nbsp;If you ever get these thoughts, contact your doctor immediately.<\/p>\n\n\n\n<p>In rare cases, severe skin and mucosal changes may occur during treatment with Fenantoin RPH Pharma.&nbsp;This risk may be related to a gene variant in people of Chinese or Thai origin.&nbsp;If you are of such origin and have previously been shown to have this genetic variant (&nbsp;<em>HLA-B * 1502)<\/em>, talk to your doctor before taking Fenantoin RPH Pharma.&nbsp;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Fenantoin RPH Pharma&nbsp;<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines. &nbsp;<\/p>\n\n\n\n<p>Some drugs used in the acidic stomach and&nbsp;peptic ulcers&nbsp;(cimetidine), some anticoagulant (&nbsp;warfarin&nbsp;), the remedies containing&nbsp;St. John&#8217;s wort&nbsp;(Hypericum perforatum), drugs used for myocardial infarction or unstable angina (ticagrelor), drugs for&nbsp;epilepsy&nbsp;(midazolam),&nbsp;P -pills&nbsp;as well as several other drugs may affect or be affected by treatment with Fenantoin RPH Pharma.<\/p>\n\n\n\n<p>The treating physician, therefore, needs to know about all other concomitant medications.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n<p>If you are pregnant or breast-feeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<br><\/p>\n\n\n\n<p>There is a risk of fetal harm effects.&nbsp;Do not use Fenantoin RPH Pharma during pregnancy except on certain&nbsp;prescriptions&nbsp;from the doctor.<br><\/p>\n\n\n\n<p>Fenantoin RPH Pharma passes into breast milk but is unlikely to affect breastfed infants.&nbsp;However, consult a physician if more than temporary use of Fenantoin RPH Pharma during breast-feeding.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>During treatment with Fenantoin RPH Pharma, the reactivity may be reduced.&nbsp;This should be taken into account when sharper attention is required, e.g.&nbsp;while driving.&nbsp;You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires increased vigilance.&nbsp;One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or&nbsp;side effects.&nbsp;Descriptions of these effects and&nbsp;side effects&nbsp;can be found in other sections.&nbsp;Read all the information in this leaflet for guidance.&nbsp;If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Fenantoin RPH Pharma contains lactose<\/h2>\n\n\n\n<p>Fenantoin RPH Pharma contains&nbsp;lactose&nbsp;.&nbsp;If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. How to use Fenantoin RPH Pharma&nbsp;<\/h2>\n\n\n\n<p>Always take this medicine exactly as your doctor has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<br><\/p>\n\n\n\n<p>Dose&nbsp;one is determined by the doctor, who adjusts it individually for you.&nbsp;Dosage&nbsp;one of Fenantoin RPH Pharma varies greatly from person to person.&nbsp;The doctor adjusts the size of the dose about the level of Fenantoin RPH Pharma in the blood, how the medicine affects the disease, and how the patient feels.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you take more Fenantoin RPH Pharma then you should&nbsp;<\/h2>\n\n\n\n<p>If you have taken too much medicine or if e.g.&nbsp;If a child has accidentally ingested the medicine, always contact a doctor, hospital, or the Poison Information Center for risk assessment and advice.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects,&nbsp;although not everybody gets them.<\/p>\n\n\n\n<p>Contact a doctor if the&nbsp;side effects&nbsp;are bothersome or long-lasting.<br><\/p>\n\n\n\n<p><em>Common (affects more than one patient in 100):<\/em>&nbsp;Drowsiness, dizziness, inability to coordinate muscle movements, tremors, involuntary eye movements, and visual disturbances.&nbsp;Growth of the gums, especially in the front of the mouth, this side effect occurs mainly in children and adolescents.&nbsp;Skin rash, hives, and increased body hair.&nbsp;Blood tests may show elevated liver values \u200b\u200b(transaminase elevation).<br><\/p>\n\n\n\n<p><em>Uncommon:<\/em>&nbsp;Digestive disorders, nausea, and vomiting.&nbsp;Lymph node changes with fever, rash, and enlargement of&nbsp;lymph nodes.<br><\/p>\n\n\n\n<p><em>Rare (affects less than one in 1000 people):<\/em>&nbsp;Confusion.&nbsp;The disease&nbsp;SLE&nbsp;(an&nbsp;autoimmune disease that can affect many organs and which often gives a typical rash over the back of the nose and cheeks).&nbsp;Decreased number of certain red and&nbsp;white blood cells and&nbsp;platelets.&nbsp;Cardiac effects, hepatitis, elevated blood sugar, and calcification of the skeleton.&nbsp;Skin and mucous membrane changes (sometimes severe).&nbsp;Severe widespread skin damage (skin detachment).<br><\/p>\n\n\n\n<p><em>Very rare (affects less than 1 in 10,000 people)<\/em>: Skin reactions, which may be life-threatening (&nbsp;Stevens-Johnson&nbsp;syndrome and&nbsp;toxic epidermal necrolysis&nbsp;) have been reported (see section 2).<br><\/p>\n\n\n\n<p>Hypersensitivity symptoms may occur, usually, within the first 2 months of treatment, see &#8220;What to think about before and when using Fenantoin RPH Pharma&#8221;.<br><\/p>\n\n\n\n<p>There have been reports of bone diseases e.g.&nbsp;decreased bone density in the skeleton, osteoporosis, and bone fractures.&nbsp;Contact a doctor or pharmacist if you are being treated with epilepsy medication for a long time, if you know you have osteoporosis or if you are on medication with&nbsp;steroids.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Fenantoin RPH Pharma<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.&nbsp;Do not use this medicine after the expiry date which is stated on the carton.&nbsp;The expiration date is the last day of the specified month.<br><\/p>\n\n\n\n<p>The medicine should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<p><em>One tablet contains: Active substance:&nbsp;<\/em>Phenytoin&nbsp;100 mg<\/p>\n\n\n\n<p><em>Other ingredients:<\/em>&nbsp;&nbsp;Lactose monohydrate 50 mg, corn starch, povidone, microcrystalline cellulose,&nbsp;colloidal&nbsp;silica, magnesium stearate.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>Fenantoin RPH Pharma 100 mg tablet is a white, flat tablet, about 8 mm in diameter, with a notch, marked FT in frames.<\/p>\n\n\n\n<p>Pack sizes<em>:<\/em>&nbsp;100 and 250 tablets in a plastic jar.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Holder of the marketing authorization \/ Information is provided by<\/h2>\n\n\n\n<p>RPH Pharmaceuticals AB<\/p>\n\n\n\n<p>Box 603<\/p>\n\n\n\n<p>101 32 Stockholm<br><\/p>\n\n\n\n<p><strong>Local representative<\/strong><\/p>\n\n\n\n<p>Astimex Pharma AB<\/p>\n\n\n\n<p>Isafjordsgatan 36&nbsp;<br>164 40 Kista<\/p>\n\n\n\n<p>Tel.&nbsp;08-5151 1535<\/p>\n\n\n\n<p>info@astimex.se<br><\/p>\n","protected":false},"excerpt":{"rendered":"<p> 100 mg tablets<br \/>\nphenytoin<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2206,2200],"tags":[3085,3087,3088,3086,2212,3081,3083,3084,3082,2211],"class_list":["post-8681","post","type-post","status-publish","format-standard","hentry","category-f","category-medicines","tag-fenantoin-rph-pharma","tag-fenantoin-rph-pharma-dose","tag-fenantoin-rph-pharma-side-effects","tag-fenantoin-rph-pharma-uses","tag-medicine","tag-phenytoin","tag-phenytoin-dose","tag-phenytoin-side-effects","tag-phenytoin-uses","tag-tablets"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8681","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=8681"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8681\/revisions"}],"predecessor-version":[{"id":9779,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8681\/revisions\/9779"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=8681"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=8681"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=8681"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}