{"id":8633,"date":"2021-03-16T10:48:41","date_gmt":"2021-03-16T10:48:41","guid":{"rendered":"https:\/\/zeepedia.com\/?p=8633"},"modified":"2023-02-14T06:27:48","modified_gmt":"2023-02-14T06:27:48","slug":"femanor","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/femanor\/","title":{"rendered":"Femanor &#8211; Estradiol Uses, Dose, And Side Effects"},"content":{"rendered":"\n<p><strong>Femanor 2 mg tablets\u00a0Estradiol, Norethisterone<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What Femanor Is And What Femanor Used For<\/h2>\n\n\n\n<p>Femanor is a preparation used for hormonal\u00a0substitution therapy\u00a0(\u00a0Hormone Replacement\u00a0Therapy,\u00a0HRT\u00a0).\u00a0It contains two female sex hormones;\u00a0estrogen\u00a0and progestogen.\u00a0Femanor is used for women whose menstruation has stopped (\u00a0menopause\u00a0) at least 1 year after their last natural menstruation. Femanor used for:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Relieve symptoms during and after menopause.<\/strong><\/li><\/ul>\n\n\n\n<p>When menstruation ends (\u00a0menopause\u00a0), the woman&#8217;s\u00a0estrogen\u00a0drops.\u00a0It can cause problems such as sweating and hot flashes.\u00a0Femanor relieves these symptoms after\u00a0menopause.\u00a0Femanor should only be used if the problems cause problems in daily life.<\/p>\n\n\n\n<p><strong>Prevent osteoporosis<\/strong><\/p>\n\n\n\n<p>After\u00a0menopause,\u00a0some women suffer from osteoporosis.\u00a0Discuss all possible options with your doctor. If you have an increased risk of\u00a0fractures\u00a0(broken bones) and other medicines that are not suitable for you, you can use Femanor to prevent osteoporosis after\u00a0menopause.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2. What You Need To Know Before Taking Femanor<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Medical Background And Regular Check-ups<\/h2>\n\n\n\n<p>The use of\u00a0HRT\u00a0involves risks that must be considered when deciding to start or continue an ongoing treatment.<\/p>\n\n\n\n<p>Experience is limited for treating women whose menstruation has stopped prematurely (when the ovaries have stopped working or the uterus has been removed).\u00a0If you belong to that group, HRT&#8217;s risks may differ.\u00a0Talk to your doctor.<\/p>\n\n\n\n<p>Before starting treatment (or resuming treatment), your doctor will ask about your and your family&#8217;s medical background.\u00a0Your doctor may do a general medical and gynecological examination, including an examination of your breasts.<\/p>\n\n\n\n<p>Once you have started treatment, you should go for regular medical check-ups at least once a year.\u00a0During these check-ups, you should discuss with your doctor the benefits and risks of continued treatment.<\/p>\n\n\n\n<p>Perform regular breast examinations according to your doctor&#8217;s recommendations.<\/p>\n\n\n\n<p><strong>Do not take Femanor:<\/strong><\/p>\n\n\n\n<p>If any of the following apply to you.\u00a0If you are not sure, talk to your doctor before taking Femanor.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>If you have or have had\u00a0<strong>breast <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/getting-a-cancer-message\/\">cancer<\/a><\/strong>\u00a0or there is a suspicion that you may have it<\/li><li>If you have or have had\u00a0<strong>estrogen-dependent cancer<\/strong>, such as cancer of the lining of the uterus (endometrium), or if there is a suspicion of such cancer.<\/li><li>If you have\u00a0<strong>unexpected genital bleeding<\/strong>\u00a0that a doctor has not investigated.<\/li><li>If you have\u00a0endometrial hyperplasia\u00a0(severe thickening of the uterine lining) and are not being treated for it.<\/li><li>If you have or have had a\u00a0blood clot in a vein\u00a0(venous\u00a0thromboembolism\u00a0), in your legs (deep\u00a0vein thrombosis\u00a0), or in your lungs (\u00a0pulmonary embolism\u00a0).<\/li><li>If you have a\u00a0coagulation disorder, a condition with an increased risk of blood clots (lack of\u00a0protein\u00a0C,\u00a0protein\u00a0S, or antithrombin).<\/li><li>If you have or have had a disease caused by blood clots in the\u00a0arteries,\u00a0are as\u00a0heart attack,\u00a0stroke\u00a0(stroke), or\u00a0angina.<\/li><li>If you have or have had any\u00a0liver disease\u00a0and still have abnormal liver values.<\/li><li>If you have\u00a0porphyria, a rare inherited blood disorder.<\/li><li>If you are allergic to estradiol, norethisterone acetate, or any of the other ingredients of this medicine (listed in section 6).<\/li><\/ul>\n\n\n\n<p>If any of the above affects you the first time you use Femanor, stop taking Femanor and contact your doctor immediately.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings And Cautions<\/h2>\n\n\n\n<p>Talk to your doctor if you have or have had any of the following problems before starting treatment.\u00a0They may recur or worsen during treatment with Femanor.\u00a0Should this occur, have more frequent check-ups with a doctor.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>If you have any disease affecting the lining of the uterus, as well as muscle knots (\u00a0fibroids\u00a0),\u00a0endometriosis,\u00a0or have had\u00a0endometrial hyperplasia\u00a0(severe thickening of the uterine lining).<\/li><li>If you have an increased risk of getting a blood clot (see below &#8220;Blood clots in a vein (\u00a0thrombosis\u00a0)&#8221;)<\/li><li>If a close relative has had breast cancer or other estrogen-dependent cancer.<\/li><li>High\u00a0blood pressure<\/li><li>Liver disease eg liver adenoma (benign\u00a0tumor\u00a0)<\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/diabetes-type-1\/\">Diabetes<\/a><\/li><li>Gallstone disease<\/li><li>If you get a\u00a0migraine\u00a0or severe headache<\/li><li>If you have <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/sle\/\">systemic lupus erythematosus<\/a> (\u00a0SLE\u00a0) &#8211; an\u00a0autoimmune\u00a0disease that affects many organs in the body<\/li><li>Epilepsy<\/li><li>Asthma<\/li><li>Otosclerosis (ossification of the middle ear leading to a hearing loss)<\/li><li>Hypertriglyceridemia\u00a0(elevated blood lipids).<\/li><li>Fluid retention due to heart or kidney disease<\/li><li>Hypothyroidism\u00a0(your\u00a0thyroid gland\u00a0does not produce enough thyroid hormone), and you are taking thyroid hormone as a replacement therapy.<\/li><li>Angioedema.\u00a0Estrogen\u00a0can cause or worsen the symptoms of\u00a0angioedema, especially if you have hereditary\u00a0angioedema.\u00a0Angioedema\u00a0can cause symptoms such as:<ul><li>Swelling of the face, tongue, or throat<\/li><li>Difficulty swallowing<\/li><li>Hives<\/li><li>Difficulty breathing<\/li><\/ul><\/li><\/ul>\n\n\n\n<p><strong>You should contact a doctor immediately and discontinue treatment if any of the following occur:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Some of what is mentioned in the section &#8216;<strong>Do not take Femanor.<\/strong>&#8216;<\/li><li>If the skin or whites of the eyes turn yellow (jaundice),\u00a0it may be a symptom of liver disease.<\/li><li>If your\u00a0blood pressure\u00a0rises sharply (symptoms may include headache, fatigue, or dizziness)<\/li><li>If you are experiencing migraine-like headaches for the first time<\/li><li>If you become pregnant<\/li><li>If you get symptoms of a blood clot, such as<ul><li>Painful swelling and redness of the legs<\/li><li>Sudden chest <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/brain-and-nerves\/pain\/\">pain<\/a><\/li><li>Breathing difficulties\u00a0<br>For more information, see below &#8220;Blood clots in a vein (\u00a0thrombosis\u00a0).&#8221;<\/li><\/ul><\/li><\/ul>\n\n\n\n<p><strong>Note:<\/strong>\u00a0Femanor is not a contraceptive.\u00a0If it is less than 12 months since your last period, or if you are under 50, you may still need to use contraception to avoid pregnancy.\u00a0Consult your doctor.<\/p>\n\n\n\n<p><em><strong>HRT\u00a0and cancer<\/strong><\/em><\/p>\n\n\n\n<p><strong>Severe thickening of the uterine lining (&nbsp;endometrial hyperplasia&nbsp;) and cancer of the uterine lining (endometrial cancer)<\/strong><\/p>\n\n\n\n<p>Using\u00a0HRT\u00a0with\u00a0estrogen\u00a0alone\u00a0increases the risk of severe thickening of the uterine lining and cancer of the uterine lining. The\u00a0progestogen in Femanor protects you against this extra risk.<\/p>\n\n\n\n<p><strong>Irregular bleeding<\/strong><\/p>\n\n\n\n<p>Irregular spotting or spotting may occur during the first 3 &#8211; 6 months of taking Femanor.<\/p>\n\n\n\n<p>But about the bleeding<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Lasts longer than 6 months<\/li><li>Starts after taking Femanor for 6 months<\/li><li>Continues after you stop taking Femanor<\/li><\/ul>\n\n\n\n<p><strong>you should see a doctor as soon as possible.<\/strong><\/p>\n\n\n\n<p><strong>Breast cancer<\/strong><\/p>\n\n\n\n<p>Data show that hormone replacement therapy (\u00a0HRT\u00a0) with a combination of\u00a0estrogen-progestogen\u00a0or with\u00a0estrogen\u00a0alone\u00a0increases the risk of breast cancer.\u00a0The increased risk depends on how long you use\u00a0HRT.\u00a0The increased risk is seen within 3 years.\u00a0When treatment is stopped, the increased risk decreases over time, but it can persist for 10 years or more if you have used\u00a0HRT\u00a0for more than 5 years.<\/p>\n\n\n\n<p><em><strong>Comparison<\/strong><\/em><\/p>\n\n\n\n<p>Of 1,000 women aged 50-54 who do not take\u00a0HRT, an average of\u00a013-17\u00a0will be diagnosed with breast cancer over 5 years.<\/p>\n\n\n\n<p>In women who are 50 years old and start taking&nbsp;HRT&nbsp;with&nbsp;estrogen&nbsp;alone&nbsp;for 5 years, 16-17 cases per 1000 users (ie 0-3 extra cases) will occur.<\/p>\n\n\n\n<p>In women who are 50 years old and start taking&nbsp;HRT&nbsp;with&nbsp;estrogen-progestogen&nbsp;for 5 years, there will be 21 cases per 1000 users (ie 4-8 extra cases).<\/p>\n\n\n\n<p>Among women aged 50\u201359 who do not use\u00a0HRT, an average of 27 out of 1,000 will be diagnosed with breast cancer over 10 years.<\/p>\n\n\n\n<p>In women who are 50 years old and start taking&nbsp;HRT&nbsp;with&nbsp;estrogen&nbsp;alone&nbsp;for 10 years, 34 cases per 1,000 users (ie 7 extra cases) will occur.<\/p>\n\n\n\n<p>In women who are 50 years old and start taking\u00a0HRT\u00a0with\u00a0estrogen-progestogen\u00a0for 10 years, 48 \u200b\u200bcases per 1,000 users (ie 21 extra cases) will occur.<\/p>\n\n\n\n<p><strong>Check your breasts regularly.&nbsp;Contact a doctor if you notice changes such as:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Indentations or pits<\/li><li>Changes in the nipple<\/li><li>Nodules you can see or feel<\/li><\/ul>\n\n\n\n<p>It is also recommended that you participate in a mammography examination when you are called to do so.\u00a0At the mammogram, you must tell the nurse\/healthcare professional examining that you are using\u00a0HRT, as this medicine may increase the density of the breasts.\u00a0An increased breast density can make detecting lumps on mammography images more difficult.<\/p>\n\n\n\n<p><strong>Ovarian cancer (&nbsp;ovarian cancer&nbsp;)<\/strong><\/p>\n\n\n\n<p>Ovarian cancer is rare &#8211; much rarer than breast cancer.\u00a0Use of\u00a0HRT\u00a0with\u00a0estrogen\u00a0alone\u00a0or combined\u00a0estrogen-progestogen\u00a0has been associated with a slightly increased risk of ovarian cancer.<\/p>\n\n\n\n<p>The risk of ovarian cancer varies with age.\u00a0For example, the diagnosis of ovarian cancer will be made on about 2 women out of 2,000 between the ages of 50 and 54 who do not take\u00a0HRT\u00a0for 5 years.\u00a0For women who have taken\u00a0HRT\u00a0for 5 years, there will be about 3 cases per 2,000 users (ie about 1 extra case).<\/p>\n\n\n\n<p><em><strong>How\u00a0HRT\u00a0affects the heart and blood circulation<\/strong><\/em><\/p>\n\n\n\n<p><strong>Blood clots in a vein (&nbsp;thrombosis&nbsp;)<\/strong><\/p>\n\n\n\n<p>The risk of\u00a0<strong>blood clots in the veins<\/strong>\u00a0is 1.3\u20133 times higher for women who take\u00a0HRT than those who do not, especially during the first year of treatment.<\/p>\n\n\n\n<p>Blood clots can be serious.\u00a0If a blood clot ends up in the lungs, it can cause chest pain, shortness of breath, collapse, or even lead death.<\/p>\n\n\n\n<p>You are more likely to get a blood clot in a vein if the following apply to you.\u00a0Tell your doctor if any of the following apply to you:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>You have not been able to walk or stand for a long time due to a major operation, injury, or illness (see also section 3, \u201cIf you need surgery\u201d)<\/li><li>You are severely overweight (\u00a0BMI\u00a0over 30 kg \/ m\u00a02\u00a0)<\/li><li>You have a coagulation disorder that requires long-term treatment with drugs that prevent blood clots.<\/li><li>If a close relative has had a blood clot in the bone, lung, or another organ<\/li><li>You have\u00a0SLE\u00a0(systemic lupus erythematosus)<\/li><li>You have cancer<\/li><\/ul>\n\n\n\n<p>The symptoms of a blood clot are described in the section &#8220;You should contact a doctor immediately and stop the treatment.&#8221;<\/p>\n\n\n\n<p><em><strong>Comparison<\/strong><\/em><\/p>\n\n\n\n<p>For women in their 50s, who do not take\u00a0HRT for over 5 years, an average of 4 &#8211; 7 out of 1000 are expected to get a blood clot in a vein.<\/p>\n\n\n\n<p>For women in their 50s who have taken\u00a0HRT\u00a0with\u00a0estrogen-progestogen\u00a0for more than 5 years, 9 &#8211; 12 out of 1000 users are expected to get a blood clot in a vein (ie 5 extra cases)<\/p>\n\n\n\n<p><strong>Heart disease (heart attack)<\/strong><\/p>\n\n\n\n<p>There is no evidence that\u00a0HRT\u00a0prevents heart attacks. For women over 60 who take\u00a0HRT\u00a0with\u00a0estrogen-progestin, the risk of developing heart disease is slightly higher than those who do not take\u00a0HRT.<\/p>\n\n\n\n<p><strong>Stroke&nbsp;(apoplexy)<\/strong><\/p>\n\n\n\n<p>The risk of\u00a0stroke\u00a0is about 1.5 times higher for those who take\u00a0HRT\u00a0than those who do not.\u00a0The risk of\u00a0stroke\u00a0is age-dependent. Therefore, the number of stroke cases\u00a0increases\u00a0due to the use of\u00a0HRT\u00a0with increasing age.<\/p>\n\n\n\n<p><em><strong>Comparison<\/strong><\/em><\/p>\n\n\n\n<p>For women in their 50s who do not take\u00a0HRT, an average of 8 out of 1000\u00a0people\u00a0is expected to have a\u00a0stroke\u00a0over 5 years.<\/p>\n\n\n\n<p>For women in their 50s who have taken\u00a0HRT\u00a0for more than 5 years, 11 out of 1000 users are expected to have a\u00a0stroke\u00a0(ie 3 extra cases)<\/p>\n\n\n\n<p><strong>Other conditions<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Using\u00a0HRT\u00a0does not prevent memory loss.\u00a0The risk of memory loss may be slightly higher in women who start using\u00a0HRT\u00a0after age 65.\u00a0Consult your doctor.<\/li><li>Gallbladder disease<\/li><li>Skin changes<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Other Medicines And Femanor<\/h2>\n\n\n\n<p>Some medicines can affect the effect of Femanor, which can lead to irregular bleeding.&nbsp;The following applies:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Medicines for\u00a0<strong>epilepsy<\/strong>\u00a0(eg phenobarbital,\u00a0phenytoin,\u00a0and carbamazepine)<\/li><li>Medicines for\u00a0<strong>tuberculosis<\/strong>\u00a0(eg rifampicin, rifabutin)<\/li><li>Drugs for\u00a0<strong>HIV\u00a0&#8211;\u00a0infection<\/strong>\u00a0(for example, nevirapine, efavirenz, ritonavir, and nelfinavir telaprevir)<\/li><li>An herbal medicine containing\u00a0<strong>St. John&#8217;s wort<\/strong>\u00a0(\u00a0<em>Hypericum perforatum<\/em>\u00a0)<\/li><li>Medicines for\u00a0<strong>fungal infections<\/strong>\u00a0containing\u00a0ketoconazole.<\/li><\/ul>\n\n\n\n<p>Tell your doctor or pharmacist if you have recently taken or might take any other medicines, including medicines obtained without a prescription and herbal remedies.<\/p>\n\n\n\n<p><strong>Results from blood tests analysis<\/strong>:<\/p>\n\n\n\n<p>If you need to take a blood sample, tell your doctor, or the person taking the blood sample, that you are taking Femanor, as it may affect the results of some tests.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, Breastfeeding, And Fertility<\/h2>\n\n\n\n<p>Femanor is intended for women whose menstruation has stopped.\u00a0If you become pregnant, stop taking Femanor and consult a doctor. <strong>Femanor should not be used if you are breastfeeding.<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving And Using Machines<\/h2>\n\n\n\n<p>Femanor does not affect your ability to drive or use tools or machines.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Femanor Contains Lactose<\/h2>\n\n\n\n<p>If your doctor has told you that you have an intolerance to some sugars, contact your doctor before taking this medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. How To Take Femanor<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Always take this medicine exactly as your doctor has told you.\u00a0Ask your doctor or pharmacist if you are unsure.<\/li><li>Take 1 tablet daily without interruption, at about the same time each day.\u00a0You can start treatment at any time, but if you switch from treatment with a sequencing drug, treatment should start immediately after your regular bleeding has stopped.<\/li><li>Your doctor will strive to\u00a0give you\u00a0the lowest\u00a0dose, which will give you relief of symptoms, and to use Femanor for the shortest time.\u00a0Talk to your doctor if you do not get any relief from the symptoms or feel the\u00a0dose\u00a0is too high.<\/li><\/ul>\n\n\n\n<p><strong>Instructions for use<\/strong>:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>The package is equipped with a weekday marking that makes it possible to check the tablet intake day by day.<\/li><li>The foil marked every week is common in several Nordic countries.<\/li><li>For some days, the day marking has different initials in Icelandic.\u00a0Therefore it says M \/ M\u00e1 (Monday), Ti \/ \u00de (Tuesday), O \/ Mi (Wednesday), To \/ Fi (Thursday), and F \/ F\u00f6 (Friday).<\/li><\/ul>\n\n\n\n<p><strong>If you need surgery<\/strong>:<\/p>\n\n\n\n<p>If you are going to have surgery, tell your doctor that you are taking Femanor.&nbsp;You may need to stop taking Femanor for 4 to 6 weeks before surgery to avoid the risk of blood clots (see section 2, \u201cBlood clots in a vein (&nbsp;thrombosis&nbsp;)\u201d).&nbsp;Ask your doctor when it is appropriate to start taking Femanor again.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If You Take More Femanor Than You Should<\/h2>\n\n\n\n<p>If you have ingested too much medicine or if e.g.&nbsp;If a child has inadvertently ingested the medicine, contact a doctor, hospital, or the Poison Information Center for risk assessment and advice.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If You Forget To take Femanor<\/h2>\n\n\n\n<p>Do not take a double\u00a0dose\u00a0to make up for a forgotten tablet.\u00a0The forgotten Femanor tablet should be taken within 12 hours. Otherwise, it should be discarded.\u00a0Forgetting a\u00a0dose\u00a0can increase the likelihood of breakthrough bleeding and spotting.<\/p>\n\n\n\n<p>If you have any further questions about the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible Femanor Side Effects<\/h2>\n\n\n\n<p>This medicine can cause side effects like all medicines, although not everybody gets them. The following diseases are more common in women who take\u00a0HRT\u00a0than those who do not:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Breast cancer<\/li><li>Severe thickening of the uterine lining (&nbsp;endometrial hyperplasia&nbsp;) or cancer of the uterine lining (endometrial cancer)<\/li><li>Ovarian cancer (&nbsp;ovarian cancer&nbsp;)<\/li><li>Blood clots in veins in bones or lungs (venous&nbsp;thromboembolism&nbsp;)<\/li><li>Heart disease<\/li><li>Stroke&nbsp;(apoplexy)<\/li><li>Probable memory loss, if treatment with&nbsp;HRT is&nbsp;started after the age of 65<\/li><\/ul>\n\n\n\n<p>See section 2 for more information on these\u00a0side effects.<\/p>\n\n\n\n<p><strong><em>Very common<\/em>\u00a0(may affect more than 1 user in 10):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Headache<\/li><li>Pain or tenderness in the breasts<\/li><li>Menstrual cramps<\/li><li>Menstrual disorders<\/li><\/ul>\n\n\n\n<p><strong><em>Common<\/em>\u00a0(may affect up to 1 in 10 people):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Fungal infection of the abdomen or genital inflammation<\/li><li>Fluid accumulation in the body<\/li><li>Depression or worsening of current depression<\/li><li>Nervousness<\/li><li>Emotional disorders<\/li><li>Altered sexual drive<\/li><li>Dizziness<\/li><li>Difficulty sleeping<\/li><li>Nausea<\/li><li>Abdominal pain<\/li><li>Tension or discomfort in the abdomen<\/li><li>Diarrhea<\/li><li>Indigestion (\u00a0dyspepsia\u00a0)<\/li><li>Acne<\/li><li>Skin rash<\/li><li>Itching<\/li><li>Dry skin<\/li><li>Leg cramps or <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/back-hurts\/\">back pain<\/a><\/li><li>Pain in the legs and arms<\/li><li>Breast edema or breast enlargement<\/li><li>Benign uterine fibroids, or deterioration or recurrent uterine fibroids<\/li><li>Heavy menstrual bleeding<\/li><li>Vaginal discharge<\/li><li>Irregular bleeding<\/li><li>Seizures of the uterus<\/li><li>Infections\u00a0in the uterus<\/li><li>Thickening of the uterine lining (\u00a0endometrial hyperplasia)<\/li><li>Pain<\/li><li>Weakness<\/li><li>Peripheral\u00a0edema\u00a0(swollen arms or legs)<\/li><li>Weight gain<\/li><\/ul>\n\n\n\n<p><em>Uncommon<\/em>&nbsp;(may affect up to 1 in 100 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Migraine<\/li><li>Severe dizziness<\/li><li>High\u00a0blood pressure<\/li><li>Concomitant\u00a0inflammation<\/li><li>A blood clot in a superficial blood vessel (vein)<\/li><li>Varicose veins<\/li><li>Vomiting<\/li><li>Gallbladder disease<\/li><li>Gallstones<\/li><li>Discolored skin<\/li><li>Muscle spasms<\/li><li>Breast cancer (see also section 2)<\/li><li>Elevated levels of\u00a0transaminases\u00a0in liver function tests<\/li><\/ul>\n\n\n\n<p><strong><em>Rare<\/em>\u00a0(may affect up to 1 in 1,000 people):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Hypersensitivity (\u00a0allergic reaction\u00a0)<\/li><li>Abnormal sensations such as ant crawling<\/li><li>Numbness<\/li><li>A blood clot in the lung (see also section 2)<\/li><li>Blockage of a blood vessel due to a migrating blood clot<\/li><li>Blood clot in a deep blood vessel (vein)<\/li><li>Muscle weakness<\/li><li>Benign uterine tumor<\/li><li>Fallopian tube cysts<\/li><li>Polyps\u00a0in the cervix<\/li><\/ul>\n\n\n\n<p><strong><em>Very rare<\/em>\u00a0(may affect up to 1 in 10,000 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>An obstruction in the liver causes jaundice<\/li><li>Increased hair on the face or body.<\/li><\/ul>\n\n\n\n<p><strong><em>Has been reported<\/em>\u00a0(occurs in an unknown number of users)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Hair loss (\u00a0alopecia\u00a0)<\/li><\/ul>\n\n\n\n<p><strong>Bleeding pattern<\/strong><\/p>\n\n\n\n<p>Some women experience breakthrough bleeding or spotting during the first months of treatment.\u00a0If such bleeding continues for longer than the first few months, starts after a period of treatment, or continues even after stopping treatment, tell your doctor as soon as possible.<\/p>\n\n\n\n<p>The following&nbsp;side effects&nbsp;have been reported with other HRTs:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Various skin diseases:<ul><li>Dark skin spots, especially on the face and neck, so-called &#8220;pregnancy spots&#8221; (chloasma)<\/li><li>Painful reddish-purple bumps on the skin (erythema nodosum)<\/li><li>Annular redness or sore rash (erythema multiforme)<\/li><\/ul><\/li><li>Dry eyes<\/li><li>Changed composition of the tear fluid.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">5. How To Store Femanor<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Do not store above 30 \u00b0 C.<\/li><li>Keep this medicine out of sight and reach of children.<\/li><li>Do not use this medicine after the expiry date stated on the carton after EXP.\u00a0Date.\u00a0.\u00a0The expiration date is the last day of the specified month.<\/li><\/ul>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.\u00a0Ask your pharmacist how to dispose of medicines that are no longer required.\u00a0These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents Of The Packaging And Other Information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content Declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substances are estradiol hemihydrate corresponding to estradiol 2 mg and norethisterone acetate 1 mg.<\/li><li>The other ingredients are\u00a0lactose monohydrate\u00a060.73 mg, dyes (black iron oxide E 172, titanium dioxide E 171), corn starch, povidone, talc, magnesium stearate, hypromellose, and macrogol.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What The Medicine Looks Like And The Contents Of The Pack<\/h2>\n\n\n\n<p>Gray tablets marked P2. Provided in\u00a0calendar packaging\u00a03 x 28 pcs.\u00a0The package is equipped with a weekday marking that makes it possible to check the Femanor tablet intake day by day.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorisation Holder<\/h2>\n\n\n\n<p>Meda AB, Box 906, 170 09 Solna.\u00a0Tel 08 &#8211; 630 19 00<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Mylan Hungary Kft.\/Mylan Hungary Ltd.<\/p>\n\n\n\n<p>Mylan utca 1,<\/p>\n\n\n\n<p>Kom\u00e1rom, 2900,<\/p>\n\n\n\n<p>Hungary<br><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Femanor is a contraceptive pill. Aside from preventing pregnancy, birth control tablets may make your periods more regular, reduce blood loss and unpleasant periods, lower your chance of ovarian cysts, and treat acne.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2206,2200],"tags":[3093,3095,3096,3094,3118,3120,3121,3119,2212,2211],"class_list":["post-8633","post","type-post","status-publish","format-standard","hentry","category-f","category-medicines","tag-estradiol","tag-estradiol-dose","tag-estradiol-side-effects","tag-estradiol-uses","tag-femanor","tag-femanor-dose","tag-femanor-side-effects","tag-femanor-uses","tag-medicine","tag-tablets"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8633","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=8633"}],"version-history":[{"count":52,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8633\/revisions"}],"predecessor-version":[{"id":48672,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8633\/revisions\/48672"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=8633"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=8633"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=8633"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}