{"id":8602,"date":"2021-03-16T10:24:23","date_gmt":"2021-03-16T10:24:23","guid":{"rendered":"https:\/\/zeepedia.com\/?p=8602"},"modified":"2021-04-10T07:45:47","modified_gmt":"2021-04-10T07:45:47","slug":"fareston","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/fareston\/","title":{"rendered":"Fareston &#8211; Toremifene uses, dose, and side effects"},"content":{"rendered":"\n<p>\n\n60 mg&nbsp;tablets&nbsp;<br>toremifene<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What Fareston is and what it is used for<\/h2>\n\n\n\n<p>Fareston contains the active substance toremifene, an antiestrogen.&nbsp;Fareston is used to treat a certain type of breast tumor in women who have had their last period.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2. What you need to know before you take Fareston<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not take Fareston<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to toremifene or any of the other ingredients of this medicine (listed in section 6).<\/li><li>if you have a thickening of the uterine lining.<\/li><li>if you have severe liver problems.<\/li><li>if you are born with or later have heart problems that cause special changes to appear on charts that show the heart&#8217;s electrical activity (&nbsp;electrocardiogram&nbsp;or&nbsp;ECG&nbsp;)<\/li><li>if you have an imbalance in the salinity of the blood, especially if you have too low a concentration of&nbsp;potassium&nbsp;in the blood (&nbsp;hypokalaemia&nbsp;) and are not currently being treated for this<\/li><li>if your heart beats very slowly (&nbsp;bradycardia&nbsp;)<\/li><li>if you have&nbsp;heart failure<\/li><li>if you have a history of abnormal heart rhythm (&nbsp;arrhythmias&nbsp;)<\/li><li>if you are taking other medicines that may affect your heart function (see section 2 Other medicines and Fareston).&nbsp;This is because Fareston can affect your heart by delaying the conduction of certain electrical signals in the heart (an extension of the&nbsp;QT interval&nbsp;).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before taking Fareston.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have uncontrolled&nbsp;diabetes<\/li><li>if you have a severely impaired general condition.<\/li><li>if you have previously had blood clots, for example in your lungs (&nbsp;pulmonary embolism&nbsp;) or your legs (deep&nbsp;vein thrombosis&nbsp;).<\/li><li>if you get an abnormal heart rhythm while taking Fareston.&nbsp;Your doctor may advise you to stop taking Fareston and perform medical tests to see how your heart is working (&nbsp;ECG&nbsp;) (see section 2 Do not take Fareston).<\/li><li>If you have any type of heart problem, including chest pain (angina).<\/li><li>If you have cancer that has spread to the skeleton (skeletal metastases) because increased calcium levels in the blood may occur at the beginning of treatment with Fareston and your doctor needs to do regular check-ups.<\/li><li>If you have been told by your doctor that you have an intolerance to some sugars, such as&nbsp;lactose&nbsp;(see section 2 Fareston contains&nbsp;lactose&nbsp;).<\/li><\/ul>\n\n\n\n<p>You will need to undergo a gynecological examination before starting treatment with Fareston and at least once a year during the time you are receiving treatment with Fareston.&nbsp;Your doctor will regularly check if you have high&nbsp;blood pressure,&nbsp;diabetes, have taken hormonal replacement&nbsp;therapy&nbsp;or if are overweight (&nbsp;BMI&nbsp;over 30).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other drugs and Fareston<\/h2>\n\n\n\n<p>Tell your doctor if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n<p>Dosage&nbsp;one of some of them may need to be changed when you are being treated with Fareston.<br><\/p>\n\n\n\n<p>This is especially true if you are taking any of the following medicines:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>diuretics&nbsp;(&nbsp;thiazide&nbsp;-type diuretics)<\/li><li>anticoagulants such as&nbsp;warfarin<\/li><li>agents for the treatment of&nbsp;epilepsy&nbsp;e.g.&nbsp;carbamazepine,&nbsp;phenytoin, phenobarbital<\/li><li>agents for the treatment of fungal infections such as&nbsp;ketoconazole, itraconazole, voriconazole, and posaconazole<\/li><li>drugs used to treat bacterial infections (&nbsp;antibiotics&nbsp;) e.g.&nbsp;erythromycin, clarithromycin, and telithromycin.<\/li><li>drugs used to treat viral infections such as&nbsp;ritonavir and nelfinavir.<\/li><\/ul>\n\n\n\n<p>Do not take Fareston with the following medicines as there is an increased risk of changes in your heart rhythm (see section 2- Do not take Fareston):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>drugs for abnormal heart rhythm (&nbsp;antiarrhythmics&nbsp;);&nbsp;such as&nbsp;quinidine, hydroquinone,&nbsp;disopyramide,&nbsp;amiodarone, sotalol, dofetilide, ibutilide<\/li><li>drugs for mental illness and behavioral disorders (&nbsp;neuroleptics&nbsp;) such as phenothiazines, pimozide, sertindole,&nbsp;haloperidol,&nbsp;and sultopride<\/li><li>medicines for&nbsp;infections&nbsp;(medicines for&nbsp;microorganisms&nbsp;) such as moxifloxacin, erythromycin (&nbsp;infusion&nbsp;), pentamidine, and medicines for&nbsp;malaria,&nbsp;especially halofantrine<\/li><li>some medicines for&nbsp;allergies&nbsp;such as terfenadine, astemizole, and mizolastine<\/li><li>certain other medicines;&nbsp;cisapride, vincamine&nbsp;intravenously, bepridil, difemanil.<\/li><\/ul>\n\n\n\n<p>If you are hospitalized or prescribed a new medicine, tell your doctor that you are taking Fareston.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>Do not use Fareston during pregnancy or breast-feeding.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Fareston does not affect the ability to drive and use machines.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Fareston contains lactose<\/h2>\n\n\n\n<p>Fareston contains&nbsp;lactose&nbsp;(28.5 mg per tablet).&nbsp;If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to take Fareston<\/h2>\n\n\n\n<p>Always take this medicine exactly as your doctor has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.&nbsp;The usual&nbsp;dose&nbsp;is one 60 mg tablet daily.&nbsp;The tablet should be swallowed.&nbsp;Fareston can be taken with or without food.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you take more Fareston then you should<\/h2>\n\n\n\n<p>Contact your doctor, pharmacist, or nearest hospital immediately.&nbsp;Symptoms of overdose may include dizziness and headache.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Fareston<\/h2>\n\n\n\n<p>If you forget to take a&nbsp;dose, take the next tablet as usual and continue treatment according to the instructions.&nbsp;Do not take a double&nbsp;dose&nbsp;to make up for a forgotten tablet<\/p>\n\n\n\n<p>If you have missed several&nbsp;doses, contact your doctor and follow his \/ her instructions.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop taking Fareston<\/h2>\n\n\n\n<p>Fareston treatment should only be stopped if your doctor has recommended it.&nbsp;If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects, although not everybody gets them.<br><\/p>\n\n\n\n<p>Very common&nbsp;side effects&nbsp;(may affect more than 1 in 10 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>hot flashes, sweating<\/li><\/ul>\n\n\n\n<p>Common&nbsp;side effects&nbsp;(may affect up to 1 in 10 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>fatigue, dizziness, depression<\/li><li>nausea, vomiting<\/li><li>skin rash,&nbsp;itching,&nbsp;edema&nbsp;(swelling) bleeding from the uterus, white discharge.<\/li><\/ul>\n\n\n\n<p>Uncommon&nbsp;side effects&nbsp;(may affect up to 1 in 100 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>headache, sleep disturbances<\/li><li>weight gain, constipation, loss of appetite<\/li><li>thickening of the uterine lining<\/li><li>blood clots eg in the lung (thromboembolic event)<\/li><li>shortness of breath,<\/li><\/ul>\n\n\n\n<p>Rare&nbsp;side effects&nbsp;(may affect up to 1 in 1,000 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>dizziness<\/li><li>growth of the uterine lining (&nbsp;polyps&nbsp;)<\/li><li>increase in liver enzymes (increased laboratory values \u200b\u200bfor&nbsp;transaminases&nbsp;in the liver)<\/li><\/ul>\n\n\n\n<p>Very rare&nbsp;side effects&nbsp;(may affect up to 1 in 10,000 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>changes in the uterine lining (endometrium), uterine cancer (endometrial cancer)<\/li><li>hair loss (&nbsp;alopecia&nbsp;)<\/li><li>cloud of the&nbsp;cornea&nbsp;of the eye&nbsp;(transient corneal cloud)<\/li><li>yellowing of the skin or whites of the eyes (jaundice)<\/li><\/ul>\n\n\n\n<p>Has been reported (occurs in an unknown number of users):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>low levels of&nbsp;white blood cells, which are important in the immune system (&nbsp;leukopenia&nbsp;)<\/li><li>low level of&nbsp;red blood cells&nbsp;(&nbsp;anemia&nbsp;)<\/li><li>low&nbsp;platelet count&nbsp;(&nbsp;thrombocytopenia&nbsp;)<\/li><li>liver inflammation (&nbsp;hepatitis&nbsp;).<\/li><\/ul>\n\n\n\n<p>You should contact your doctor immediately if you notice any of the following:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>swelling or tenderness in the calf<\/li><li>unexplained shortness of breath or sudden chest pain<\/li><li>vaginal bleeding or changes in vaginal discharge.<\/li><\/ul>\n\n\n\n<p>Fareston causes abnormal changes in charts that show the electrical activity of the heart (&nbsp;electrocardiogram&nbsp;or&nbsp;ECG&nbsp;).&nbsp;See section 2- Warnings and Precautions.<br><\/p>\n\n\n\n<p><strong>Reporting of&nbsp;side effects&nbsp;ar<\/strong><\/p>\n\n\n\n<p>If you get&nbsp;any side effects, talk to your doctor or pharmacist.&nbsp;This also applies to&nbsp;side effects&nbsp;that are not mentioned in this information.&nbsp;You can also report&nbsp;side effects directly via:<br><\/p>\n\n\n\n<p>The Medical Products Agency<\/p>\n\n\n\n<p>Box 26<\/p>\n\n\n\n<p>SE-751 03 Uppsala<\/p>\n\n\n\n<p>Website:&nbsp;www.lakemedelsverket.se<br><\/p>\n\n\n\n<p>By reporting&nbsp;side effects, you can help increase drug safety information.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Fareston<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<br><\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the label.&nbsp;The expiration date is the last day of the specified month.<br><\/p>\n\n\n\n<p>This medicine does not require any special storage conditions.<br><\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is toremifene;&nbsp;each tablet contains 60 mg (as citrate).<\/li><li>The other ingredients are corn starch,&nbsp;lactose monohydrate, povidone, sodium starch glycollate, microcrystalline cellulose,&nbsp;colloidal&nbsp;anhydrous silica, magnesium stearate.<\/li><\/ul>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>White, round, flat tablets with beveled edges, marked TO 60 on one side.<\/p>\n\n\n\n<p>30 and 100 tablets.<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p>Orion Corporation<\/p>\n\n\n\n<p>Orionintie 1<\/p>\n\n\n\n<p>FI-02200 Espoo<\/p>\n\n\n\n<p>Finland<br><\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Orion Corporation Orion Pharma<\/p>\n\n\n\n<p>Joensuunkatu 7<\/p>\n\n\n\n<p>FI-24100 Salo<\/p>\n\n\n\n<p>Finland<br><\/p>\n","protected":false},"excerpt":{"rendered":"<p>60 mg tablets<br \/>\ntoremifene<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2206,2200],"tags":[3196,3198,3199,3197,2212,2210,3192,3194,3195,3193],"class_list":["post-8602","post","type-post","status-publish","format-standard","hentry","category-f","category-medicines","tag-fareston","tag-fareston-dose","tag-fareston-side-effects","tag-fareston-uses","tag-medicine","tag-tablet","tag-toremifene","tag-toremifene-dose","tag-toremifene-side-effects","tag-toremifene-uses"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8602","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=8602"}],"version-history":[{"count":5,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8602\/revisions"}],"predecessor-version":[{"id":9839,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8602\/revisions\/9839"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=8602"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=8602"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=8602"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}