{"id":8588,"date":"2021-03-15T08:23:49","date_gmt":"2021-03-15T08:23:49","guid":{"rendered":"https:\/\/zeepedia.com\/?p=8588"},"modified":"2021-04-10T08:04:00","modified_gmt":"2021-04-10T08:04:00","slug":"ezetimib-krka","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/ezetimib-krka\/","title":{"rendered":"Ezetimib Krka &#8211; Ezetimibe uses, dose, and side effects"},"content":{"rendered":"\n<p>\n\n10 mg&nbsp;tablets&nbsp;<br>ezetimibe<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What Ezetimibe Krka is and what it is used for<\/h2>\n\n\n\n<p>Ezetimibe Krka is a drug used to lower elevated blood&nbsp;cholesterol levels.<br><\/p>\n\n\n\n<p>Ezetimibe Krka lowers the blood levels of total cholesterol, the &#8220;bad&#8221;&nbsp;cholesterol&nbsp;(&nbsp;LDL-&nbsp;cholesterol&nbsp;), and a type of blood fat called&nbsp;triglycerides&nbsp;&nbsp;Ezetimibe Krka also increases the levels of &#8220;good&#8221;&nbsp;cholesterol&nbsp;(&nbsp;HDL&nbsp;&#8211;&nbsp;cholesterol&nbsp;).<br><\/p>\n\n\n\n<p>Ezetimibe, the active ingredient in Ezetimibe Krka, works by reducing cholesterol uptake into the gastrointestinal tract.<br><\/p>\n\n\n\n<p>Ezetimibe Krka enhances the cholesterol-lowering effect of statins, a group of drugs that reduce the amount of&nbsp;cholesterol&nbsp;that your body produces itself.<\/p>\n\n\n\n<p>Cholesterol&nbsp;is one of several fats found in your blood.&nbsp;Your total cholesterol is made up mainly of&nbsp;LDL&nbsp;&#8211; and&nbsp;HDL&nbsp;&#8211;&nbsp;cholesterol.<br><\/p>\n\n\n\n<p>LDL&nbsp;&#8211;&nbsp;cholesterol&nbsp;is often called &#8220;bad&#8221;&nbsp;cholesterol&nbsp;et because it can build up in the walls of your arteries and form&nbsp;plaque.&nbsp;This&nbsp;plaque&nbsp;\u2011 storage can eventually lead to a narrowing of your&nbsp;vessels.&nbsp;This narrowing can reduce or block blood flow to important organs such as the heart and brain.&nbsp;Blockage of blood flow can result in a heart attack or&nbsp;stroke.<br><\/p>\n\n\n\n<p>HDL&nbsp;&#8211;&nbsp;cholesterol&nbsp;is often called &#8220;good&#8221;&nbsp;cholesterol&nbsp;et because it helps prevent the &#8220;bad&#8221;&nbsp;cholesterol&nbsp;et from building up in container&nbsp;one and protects against heart disease.<br><\/p>\n\n\n\n<p>Triglycerides&nbsp;are another type of fat in the blood that can increase the risk of heart disease.<br><\/p>\n\n\n\n<p>It is used in pre-patients who cannot control their cholesterol levels through a cholesterol-lowering diet alone.&nbsp;You should continue with a cholesterol-lowering diet while you are taking this medicine.<br><\/p>\n\n\n\n<p><strong>Ezetimibe Krka is used as a supplement to your cholesterol-lowering diet if you have:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>elevated blood cholesterol levels (primary&nbsp;hypercholesterolemia&nbsp;(&nbsp;heterozygous familial and non-familial))<ul><li>along with a statin, when a statin alone does not provide adequate control of your cholesterol levels<\/li><li>alone, when treatment with statins is considered inappropriate or if you do not tolerate statins<\/li><\/ul><\/li><li>an inherited disease (&nbsp;homozygous&nbsp;familial&nbsp;hypercholesterolemia&nbsp;) that causes elevated cholesterol levels in the blood.&nbsp;You will also be prescribed treatment with a statin and may also receive other treatment.<\/li><\/ul>\n\n\n\n<p>If you have heart disease, Ezetimibe Krka in combination with cholesterol-lowering medicines called statins may reduce the risk of heart attack,&nbsp;stroke, surgery to increase blood flow to the heart, or hospitalization for chest pain.<br><\/p>\n\n\n\n<p>Ezetimibe Krka does not help you lose weight.<br><\/p>\n\n\n\n<p>Ezetimibe contained in Ezetimibe Krka may also be approved for the treatment of other conditions not mentioned in this product information.&nbsp;Ask your doctor, pharmacist, or other healthcare professional if you have any further questions, and always follow their instructions.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you use Ezetimibe Krka<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Ezetimibe Krka<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to ezetimibe or any of the other ingredients of this medicine (listed in section 6).<\/li><\/ul>\n\n\n\n<p><strong>Do not take Ezetimibe Krka with a statin if:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>you have liver problems<\/li><li>you are pregnant or breastfeeding<\/li><\/ul>\n\n\n\n<p>If you are taking Ezetimibe Krka with a statin, also read the package leaflet for that medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before taking Ezetimibe Krka.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Inform your doctor about all your medical ailments, including&nbsp;allergies.<\/li><li>Your doctor should take a blood test before you start taking Ezetimibe Krka with a statin.&nbsp;This blood test is taken to check your liver function.<\/li><li>Your doctor may also need to take a blood test to check your liver function after you start taking Ezetimibe Krka with a statin.<\/li><li>Ezetimibe Krka is not recommended if you have moderate to severe hepatic impairment.<\/li><li>The safety and efficacy of the concomitant use of Ezetimibe Krka and certain cholesterol-lowering drugs called fibrates have not been established.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>Do not give this medicine to children and adolescents (aged 6 to 17 years) unless it has been prescribed by a specialist as there are limited data on safety and efficacy.<br><\/p>\n\n\n\n<p>Do not give this medicine to children under 6 years of age as there is no information for this age group.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Ezetimibe Krka<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.&nbsp;In particular, tell your doctor if you are taking medicines with any of the following active ingredients:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>ciclosporin (often used by organ transplant patients)<\/li><li>drugs with an active ingredient that&nbsp;prevent&nbsp;blood clots, such as&nbsp;warfarin, phenprocoumon, acenocoumarol, or fluindione (so-called&nbsp;anticoagulants&nbsp;)<\/li><li>cholestyramine (also used to lower cholesterol), as it affects the effect of Ezetimibe Krka<\/li><li>fibrates (also used to lower cholesterol)<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n<p>Do not take Ezetimibe Krka with a statin if you are pregnant, trying to conceive, or think you may be pregnant.&nbsp;If you become pregnant while taking Ezetimibe Krka with a statin, stop taking both medicines immediately and tell your doctor.&nbsp;There is no experience with the use of Ezetimibe Krka without a statin during pregnancy.&nbsp;If you are pregnant, consult your doctor before using Ezetimibe Krka.<br><\/p>\n\n\n\n<p>Do not take Ezetimibe Krka with a statin if you are breast-feeding as it is unknown if the medicines pass into breast milk.&nbsp;Ezetimibe Krka without a statin should not be used if you are breast-feeding.&nbsp;Consult a doctor.<br><\/p>\n\n\n\n<p>Ask your doctor or pharmacist for advice before taking any medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Ezetimibe Krka is not expected to affect your ability to drive or use machines.&nbsp;However, some people may get dizzy when they take Ezetimibe Krka.<br><\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.&nbsp;One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or&nbsp;side effects.&nbsp;Descriptions of these effects and&nbsp;side effects&nbsp;can be found in other sections.&nbsp;Read all the information in this leaflet for guidance.&nbsp;If you are not sure, talk to your doctor or pharmacist.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Ezetimibe Krka<\/h2>\n\n\n\n<p>Always take this medicine exactly as your doctor has told you.&nbsp;Continue to take your other cholesterol-lowering medications, unless your doctor tells you to stop.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Before you start taking Ezetimibe Krka you should keep a cholesterol-lowering diet.<\/li><li>You should continue with this cholesterol-lowering diet while you are taking Ezetimibe Krka.<\/li><\/ul>\n\n\n\n<p>The recommended&nbsp;dose&nbsp;is one tablet of Ezetimibe Krka 10 mg once daily by mouth.<br><\/p>\n\n\n\n<p>Ezetimibe Krka can be taken at any time of the day and can be taken with or without food.<\/p>\n\n\n\n<p>If your doctor has prescribed Ezetimibe Krka with a statin, both medicines can be taken at the same time.&nbsp;Then also read the dosing instructions in the package leaflet for that medicine.<\/p>\n\n\n\n<p>If your doctor has prescribed Ezetimibe Krka together with another cholesterol-lowering medicine that contains the active ingredient cholestyramine or any other bile acid sequestrant, you should take Ezetimibe Krka at least 2 hours before or 4 hours after taking the bile acid sequestrant.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you use more Ezetimibe Krka then you should&nbsp;<\/h2>\n\n\n\n<p>If you have ingested too much medicine or if, for example, a child has accidentally ingested the medicine, contact a doctor, pharmacy staff, hospital, or the Poison Information Center for risk assessment and advice.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to use Ezetimibe Krka<\/h2>\n\n\n\n<p>Do not take a double&nbsp;dose&nbsp;to make up for a forgotten tablet.&nbsp;Just take your usual dose of Ezetimibe Krka at the usual time the next day.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop using Ezetimibe Krka<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist as your cholesterol levels may rise again.<br><\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects, although not everybody gets them.<br><\/p>\n\n\n\n<p><strong>Contact a doctor immediately if you experience unexplained muscle aches, soreness, or weakness.&nbsp;The reason for this is that in rare cases, muscle problems, including the breakdown of muscles with kidney damage, as a result, can be serious and become life-threatening.<\/strong><br><\/p>\n\n\n\n<p>Allergic reactions including swelling of the face, lips, tongue, and\/or throat that may cause breathing or swallowing difficulties (requiring immediate treatment) have been reported during normal use.<br><\/p>\n\n\n\n<p><strong>When ezetimibe alone was used, the following adverse reactions were reported:<\/strong><br><\/p>\n\n\n\n<p><em>Common (may affect up to 1 in 10 people):<\/em>&nbsp;abdominal pain, diarrhea, flatulence, fatigue.<br><\/p>\n\n\n\n<p><em>Uncommon (may affect up to 1 in 100 people):<\/em>&nbsp;elevations of certain blood test values \u200b\u200bshowing liver function (&nbsp;transaminases&nbsp;) and muscle function (CK), cough, indigestion, heartburn, nausea, joint pain, muscle cramps, decreased neck pain, decreased appetite, pain, chest pain, hot&nbsp;flushing&nbsp;(&nbsp;flushing&nbsp;), high&nbsp;blood pressure.<br><\/p>\n\n\n\n<p><strong>When ezetimibe was used with a statin, the following side effects were also reported:<\/strong><br><\/p>\n\n\n\n<p><em>Common (may affect up to 1 in 10 people):<\/em>&nbsp;elevations of certain blood test values \u200b\u200bshowing liver function (&nbsp;transaminases&nbsp;), headache, muscle aches, tenderness, or weakness.<br><\/p>\n\n\n\n<p><em>Uncommon (may affect up to 1 in 100 people):<\/em>&nbsp;tingling sensation, dry mouth,&nbsp;itching, rash, hives, back pain, muscle weakness, pain in arms and legs, unusual tiredness or weakness, swelling, especially in hands and feet.<\/p>\n\n\n\n<p>When ezetimibe was used with fenofibrate, the following common side effects were reported: abdominal pain.<br><\/p>\n\n\n\n<p><em>The following&nbsp;side effects&nbsp;have also been reported with normal use&nbsp;(&nbsp;occurs in unknown numbers of users&nbsp;):<\/em>&nbsp;dizziness, muscle aches, liver problems, allergic reactions including skin and&nbsp;hives, raised red, sometimes target-like rash (&nbsp;<em>erythema multiforme<\/em>&nbsp;), muscle aches, tenderness, or weakness, muscle breakdown,&nbsp;gallstones or&nbsp;gallbladder&nbsp;inflammation&nbsp;(which can cause abdominal pain, nausea, vomiting),&nbsp;inflammation&nbsp;of the pancreas, often with severe abdominal pain, constipation, decreased&nbsp;platelet count&nbsp;which can cause bruising\/bleeding (&nbsp;thrombocytopenia), stinging sensation, depression, unusual tiredness or weakness, shortness of breath.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Ezetimibe Krka<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<br><\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton after EXP.&nbsp;The expiration date is the last day of the specified month.<br><\/p>\n\n\n\n<p>Store in the original package.&nbsp;Moisture sensitive.<br><\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is ezetimibe.&nbsp;Each tablet contains 10 mg of ezetimibe.<\/li><li>The other ingredients are sodium lauryl sulfate, povidone K30, mannitol (E421), croscarmellose sodium, microcrystalline cellulose, (E460), and sodium stearyl fumarate.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>The tablets are white to off-white, capsule-shaped tablets with beveled edges.&nbsp;The tablet dimensions are 8 x 4 mm.<br><\/p>\n\n\n\n<p><em>Ezetimibe&nbsp;<\/em><em>Krka is available in cartons containing:<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Blister (OPA \/ Alu \/ PVC \/\/ Alu): 14, 28, 30, 50, 56, 60, 90, 98, 100 tablets<\/li><li>Blisters (perforated unit dose blisters, OPA \/ Alu \/ PVC \/\/ Alu): 14 x 1, 28 x 1, 30 x 1, 50 x 1, 56 x 1, 60 x 1, 90 x 1, 98 x 1, 100 x 1 tablets.<\/li><\/ul>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p><strong>Marketing Authorisation Holder<\/strong><\/p>\n\n\n\n<p>KRKA, dd, Novo mesto, \u0160marje\u0161ka cesta 6, 8501 Novo mesto, Slovenia<br><\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>KRKA, dd, Novo mesto, \u0160marje\u0161ka cesta 6, 8501 Novo mesto, Slovenia<\/p>\n\n\n\n<p>TAD Pharma GmbH, Heinz-Lohmann-Strasse 5, 27472 Cuxhaven, Germany<br><\/p>\n","protected":false},"excerpt":{"rendered":"<p> 10 mg tablets<br \/>\nezetimibe<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2205,2200],"tags":[3248,3250,3251,3249,3224,3226,3227,3225,2212,2210],"class_list":["post-8588","post","type-post","status-publish","format-standard","hentry","category-e","category-medicines","tag-ezetimib-krka","tag-ezetimib-krka-dose","tag-ezetimib-krka-side-effects","tag-ezetimib-krka-uses","tag-ezetimibe","tag-ezetimibe-dose","tag-ezetimibe-side-effects","tag-ezetimibe-uses","tag-medicine","tag-tablet"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8588","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=8588"}],"version-history":[{"count":5,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8588\/revisions"}],"predecessor-version":[{"id":9856,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8588\/revisions\/9856"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=8588"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=8588"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=8588"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}