{"id":8560,"date":"2021-03-15T07:44:15","date_gmt":"2021-03-15T07:44:15","guid":{"rendered":"https:\/\/zeepedia.com\/?p=8560"},"modified":"2021-04-12T15:25:48","modified_gmt":"2021-04-12T15:25:48","slug":"exemestan-sandoz","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/exemestan-sandoz\/","title":{"rendered":"Exemestan Sandoz &#8211; Exemestane uses, dose and side effects"},"content":{"rendered":"\n<p>\n\n25 mg&nbsp;film-coated tablets&nbsp;<br>exemestane<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What Exemestane Sandoz is and what it is used for<\/h2>\n\n\n\n<p>Exemestane Sandoz belongs to a group of medicines called aromatase inhibitors.&nbsp;These drugs affect a substance called&nbsp;aromatase, which is necessary for the production of female sex hormones,&nbsp;estrogen, especially in women who have passed menopause.&nbsp;Reducing estrogen levels in the body is one way to treat hormone-dependent breast cancer.<br><\/p>\n\n\n\n<p>Exemestane Sandoz is used to treating early hormone-dependent breast cancer in women who have passed menopause, after undergoing 2 to 3 years of treatment with tamoxifen.<br><\/p>\n\n\n\n<p>Exemestane Sandoz is also used to treat hormone-dependent advanced breast cancer in women who have passed menopause when another hormone replacement therapy has not worked satisfactorily.<br><\/p>\n\n\n\n<p>Exemestane contained in Exemestane Sandoz may also be approved for the treatment of other conditions not mentioned in this leaflet.&nbsp;Ask your doctor, pharmacist, or another healthcare professional if you have any further questions, and always follow their instructions.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before taking Exemestane Sandoz<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not take Exemestane Sandoz<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are or have previously been shown to be allergic to exemestane or any of the other ingredients of this medicine (listed in section 6).<\/li><li>if you have not passed menopause, ie.&nbsp;if you are still menstruating.<\/li><li>if you are pregnant or planning to become pregnant or breast-feeding.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before taking Exemestan Sandoz.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Before starting treatment with Exemestane Sandoz, your doctor may want to take a blood sample to make sure you are past menopause.<\/li><li>Before you start using Exemestane Sandoz, tell your doctor if you have liver or kidney problems.<\/li><li>Tell your doctor if you are in, or have been in before, conditions that affect the strength of the bone structure.&nbsp;Your doctor may want to measure your bone density before and during treatment with Exemestane Sandoz.&nbsp;This is because drugs of this type lower the levels of female&nbsp;hormones&nbsp;that can cause a decrease in the mineral content of the bone structure, which in turn can lead to poorer bone strength.<\/li><li>Your doctor may consider giving you&nbsp;vitamin&nbsp;D supplements&nbsp;as it is common for women with early breast cancer to have severe vitamin D deficiency.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Exemestane Sandoz<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.<br><\/p>\n\n\n\n<p>Exemestane Sandoz should not be given at the same time as hormone replacement therapy (&nbsp;HRT&nbsp;).<br><\/p>\n\n\n\n<p>Tell your doctor if you are taking any of the following medicines:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>rifampicin (&nbsp;antibiotic&nbsp;)<\/li><li>carbamazepine or&nbsp;phenytoin&nbsp;(an&nbsp;anticonvulsant&nbsp;drug used to treat&nbsp;epilepsy&nbsp;)<\/li><li>herbal medicine used for mild depression and mild anxiety (containing&nbsp;St. John&#8217;s wort,&nbsp;<em>Hypericum perforatum<\/em>&nbsp;)<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Exemestane Sandoz with food and drink<\/h2>\n\n\n\n<p>The Exemestan Sandoz tablet should be taken after a meal at about the same time each day.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>Do not take Exemestane Sandoz if you are pregnant or breast-feeding.&nbsp;If you are pregnant or breast-feeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<br><\/p>\n\n\n\n<p>Discuss contraception with your doctor if there is a risk that you may become pregnant.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>If you feel drowsy, dizzy, or weak while taking Exemestan Sandoz, do not drive or use machines.<br><\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.&nbsp;One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or&nbsp;side effects.&nbsp;Descriptions of these effects and&nbsp;side effects&nbsp;can be found in other sections.&nbsp;Read all the information in this leaflet for guidance.&nbsp;If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Exemestane Sandoz contains sodium<\/h2>\n\n\n\n<p>This medicine contains less than 1 mmol (23 mg)&nbsp;sodium&nbsp;per film-coated tablet, ie it is essentially &#8216;sodium-free&#8217;.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to take Exemestane Sandoz<\/h2>\n\n\n\n<p>Always take this medicine exactly as your doctor has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<br><\/p>\n\n\n\n<p>Exemestane Sandoz tablets should be taken after a meal at about the same time each day.<br><\/p>\n\n\n\n<p>The recommended&nbsp;dose&nbsp;is one 25 mg tablet daily.<br><\/p>\n\n\n\n<p>If you need to visit a hospital while taking Exemestan Sandoz, tell your healthcare provider what medicines you are taking.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Use for children<\/h2>\n\n\n\n<p>Exemestane Sandoz is not suitable for children.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you take more Exemestan Sandoz then you should<\/h2>\n\n\n\n<p>If you have ingested too much medicine or if e.g.&nbsp;a child ingested the medicine by mistake, contact a doctor, hospital, or the Poison Information Center for risk assessment and advice.&nbsp;Show them the package with Exemestan Sandoz.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Exemestane Sandoz<\/h2>\n\n\n\n<p>Do not take a double&nbsp;dose&nbsp;to make up for a forgotten tablet.<\/p>\n\n\n\n<p>If you forget to take your tablet, take it as soon as you remember.&nbsp;If it is almost time for&nbsp;your&nbsp;next&nbsp;dose, take this tablet at the usual time.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop taking Exemestane Sandoz<\/h2>\n\n\n\n<p>Do not stop taking the tablets even if you feel well unless your doctor has told you to.<br><\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects, although not everybody gets them.<br><\/p>\n\n\n\n<p>Exemestane Sandoz is generally well tolerated and the following&nbsp;side effects observed in patients treated with Exemestane tablets are usually mild or moderate in nature.&nbsp;Most of the&nbsp;side effects&nbsp;are associated with estrogen deficiency (eg hot flashes).<br><\/p>\n\n\n\n<p>Contact a doctor immediately if you think you have been affected by the following:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>severe allergic reactions.&nbsp;Symptoms include rash,&nbsp;itching,&nbsp;hives, difficulty breathing or swallowing, and dizziness.<\/li><li>inflammation&nbsp;of the liver (&nbsp;hepatitis&nbsp;).&nbsp;Symptoms include general malaise, nausea, jaundice (yellowing skin or eyes),&nbsp;itching, right-sided abdominal pain, and decreased appetite.<\/li><\/ul>\n\n\n\n<p>The following other&nbsp;side effects&nbsp;have been reported in people taking exemestane tablets.<br><\/p>\n\n\n\n<p><strong>Very common (may affect more than 1 user in 10):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>difficulty sleeping<\/li><li>headache<\/li><li>hot flashes<\/li><li>nausea<\/li><li>increased sweating<\/li><li>muscle and joint pain (including&nbsp;osteoarthritis, back pain and&nbsp;inflammation,&nbsp;and stiffness in the joints)<\/li><li>fatigue.<\/li><\/ul>\n\n\n\n<p><strong>Common (may affect up to 1 in 10 people):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>loss of appetite<\/li><li>Depression<\/li><li>dizziness<\/li><li>tingling or numbness in the hands or feet<\/li><li>carpal tunnel syndrome&nbsp;(pain and numbness in the whole hand except the little finger)<\/li><li>abdominal pain, vomiting, constipation, digestive problems, diarrhea<\/li><li>skin rash,&nbsp;itching&nbsp; hair loss<\/li><li>impaired skeletal strength (osteoporosis) which can sometimes lead to&nbsp;fractures(fractures or cracks)<\/li><li>pain, swollen hands, and feet.<\/li><\/ul>\n\n\n\n<p><strong>Uncommon (may affect up to 1 in 100 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>decreased number of&nbsp;white blood cells, which increases the risk of&nbsp;infection.&nbsp;Symptoms can include fever, sore throat, or mouth ulcers due to&nbsp;infection&nbsp;s<\/li><li>an acute&nbsp;widespread rash with varicose veins (&nbsp;acute&nbsp;generalized exanthematous&nbsp;pustulosis&nbsp;)<\/li><li>drowsiness<\/li><li>weakness in the muscles.<\/li><\/ul>\n\n\n\n<p><strong>Rare&nbsp;side effects&nbsp;(may affect up to 1 in 1,000 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>decreased&nbsp;platelet count&nbsp;(with an increased risk of bleeding and bruising).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Exemestan Sandoz<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<br><\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton\/blister after &#8220;EXP&#8221;.<\/p>\n\n\n\n<p>The expiration date is the last day of the specified month.<br><\/p>\n\n\n\n<p>No special storage instructions.<br><\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is exemestane.&nbsp;One film-coated tablet contains 25 mg of exemestane.<\/li><li>The other ingredients are mannitol, microcrystalline cellulose, crospovidone, sodium starch glycolate (Type A), hypromellose E5, polysorbate 80,&nbsp;colloidal anhydrous silica, magnesium stearate, hypromellose 6cp (E 464), titanium dioxide (E 171), and macrogol 400.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>White to off-white, round, biconvex film-coated tablets marked with \u201cE25\u201d on one side and unlabeled on the other side.<br><\/p>\n\n\n\n<p>The film-coated tablets are packaged in white, opaque PVC \/ PVdC-Al pressure packs in a carton.<br><\/p>\n\n\n\n<p>Pack sizes:<\/p>\n\n\n\n<p>15, 20, 28, 30, 90, 98, 100, 120 film-coated tablets.<br><\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p><em>Marketing Authorisation Holder<\/em><\/p>\n\n\n\n<p>Sandoz A \/ S, Edvard Thomsens Vej 14, 2300 Copenhagen S, Denmark<br><\/p>\n\n\n\n<p><em>Manufacturer<\/em><\/p>\n\n\n\n<p>SC Sandoz SRL, Str. Livezeni no.&nbsp;7A, 540472 Targu-Mures, Romania<\/p>\n\n\n\n<p>or<\/p>\n\n\n\n<p>Salutas Pharma GmbH, Otto-von-Guericke-Allee 1, 39179 Barleben, Germany<br><\/p>\n","protected":false},"excerpt":{"rendered":"<p> 25 mg film-coated tablets<br \/>\nexemestane<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2205,2200],"tags":[3326,3328,3346,3348,3349,3347,3329,3327,2212,2211],"class_list":["post-8560","post","type-post","status-publish","format-standard","hentry","category-e","category-medicines","tag-exemestane","tag-exemestane-dose","tag-exemestane-sandoz","tag-exemestane-sandoz-dose","tag-exemestane-sandoz-side-effects","tag-exemestane-sandoz-uses","tag-exemestane-side-effects","tag-exemestane-uses","tag-medicine","tag-tablets"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8560","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=8560"}],"version-history":[{"count":6,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8560\/revisions"}],"predecessor-version":[{"id":10049,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8560\/revisions\/10049"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=8560"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=8560"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=8560"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}