{"id":8514,"date":"2021-03-13T09:14:38","date_gmt":"2021-03-13T09:14:38","guid":{"rendered":"https:\/\/zeepedia.com\/?p=8514"},"modified":"2022-10-23T07:18:27","modified_gmt":"2022-10-23T07:18:27","slug":"eviana","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/eviana\/","title":{"rendered":"Eviana &#8211; Estradiol Uses, Dose, And Side Effects"},"content":{"rendered":"\n<p><strong> Film-coated tablets,\u00a0Eviana hormone replacement<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What Eviana Is And What It Is Used For<\/h2>\n\n\n\n<p><strong>Eviana 0.5 mg <\/strong>is a preparation used for continuous&nbsp;hormonal&nbsp;substitution therapy&nbsp;(&nbsp;Hormone&nbsp;Replacement&nbsp;Therapy,&nbsp;HRT&nbsp;).&nbsp;<\/p>\n\n\n\n<p><strong>Eviana hormone replacement<\/strong> contains two female sex hormones<\/p>\n\n\n\n<ol class=\"wp-block-list\"><li>Estrogen<\/li><li>Progestogen<\/li><\/ol>\n\n\n\n<p><strong>Eviana 0.5 mg<\/strong> is used in women whose period has stopped (&nbsp;menopause&nbsp;), at least 1 year after their last natural menstrual period.<\/p>\n\n\n\n<p>Eviana is used to:<\/p>\n\n\n\n<p><strong>Relieve symptoms during and after menopause<\/strong><\/p>\n\n\n\n<p>When menstruation ceases (&nbsp;menopause&nbsp;), a woman&#8217;s&nbsp;estrogen&nbsp;drops.&nbsp;It can cause problems such as sweating and hot flashes.&nbsp;Eviana relieves these symptoms after&nbsp;menopause.&nbsp;Eviana should only be used if the problems cause problems in daily life.<\/p>\n\n\n\n<p><strong>Eviana 0.5 mg<\/strong> is prescribed to women who have their uterus left and who had their last menstrual period more than a year ago.<\/p>\n\n\n\n<p>Experience in the treatment of women older than 65 years is limited.<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><a href=\"https:\/\/amzn.to\/3MY0Evd\" rel=\"noopener\"><img loading=\"lazy\" decoding=\"async\" width=\"285\" height=\"283\" src=\"https:\/\/zeepedia.com\/wp-content\/uploads\/2022\/10\/eviana.png\" alt=\"Eviana\" class=\"wp-image-27922\" srcset=\"https:\/\/zeepedia.com\/medical\/wp-content\/uploads\/2022\/10\/eviana.png 285w, https:\/\/zeepedia.com\/medical\/wp-content\/uploads\/2022\/10\/eviana-150x150.png 150w\" sizes=\"auto, (max-width: 285px) 100vw, 285px\" \/><\/a><figcaption>Eviana &#8211; Estradiol<\/figcaption><\/figure><\/div>\n\n\n<h2 class=\"wp-block-heading\">2. What You Need To Know Before Taking Eviana<\/h2>\n\n\n\n<p><strong>Medical background and regular check-ups<\/strong><\/p>\n\n\n\n<p>The use of&nbsp;HRT&nbsp;involves risks that must be taken into account when deciding to start treatment or continue an ongoing treatment.<br><\/p>\n\n\n\n<p>Experience is limited for the treatment of women whose menstruation has stopped prematurely (when the ovaries have stopped working or the uterus has been removed).&nbsp;If you belong to that group, the risks of&nbsp;HRT&nbsp;may be different.&nbsp;Talk to your doctor.<br><\/p>\n\n\n\n<p>Before starting treatment (or resuming treatment), your doctor will ask about your own, and your family&#8217;s medical background.&nbsp;Your doctor may do a general medical and gynecological examination, which also includes an examination of your breasts.<br><\/p>\n\n\n\n<p>Once you have started treatment with Eviana, you should go for regular medical check-ups, at least once a year.&nbsp;During these check-ups, you should discuss with your doctor the benefits and risks of continued treatment.<br><\/p>\n\n\n\n<p>Perform regular breast examinations according to your doctor&#8217;s recommendations.<br><\/p>\n\n\n\n<p><strong>Do not take Eviana<\/strong><\/p>\n\n\n\n<p>if any of the following apply to you.&nbsp;If you are not sure,&nbsp;<strong>talk to your doctor<\/strong>&nbsp;before taking Eviana.<\/p>\n\n\n\n<p>Do not take Eviana because of the <strong>side effects of estradiol<\/strong>:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>If you have or have had\u00a0<strong>breast cancer<\/strong>\u00a0or there is a suspicion that you may have it.<\/li><li>If you have or have had\u00a0<strong>estrogen-dependent cancer,<\/strong>\u00a0such as cancer of the uterine lining (endometrium), or if there is a suspicion of such cancer.<\/li><li>If you have\u00a0unexpected genital bleeding\u00a0that has not been investigated by a doctor.<\/li><li>if you have\u00a0severe thickening of the uterine lining\u00a0(\u00a0endometrial hyperplasia\u00a0) and are not treated for it.<\/li><li>If you have or have had a\u00a0blood clot in a vein\u00a0(venous\u00a0thromboembolism\u00a0),\u00a0in your legs\u00a0(deep\u00a0vein thrombosis\u00a0),\u00a0<strong>or in your lungs\u00a0<\/strong>(\u00a0pulmonary embolism\u00a0).<\/li><li>If you have a\u00a0<strong>coagulation disorder,<\/strong>\u00a0a condition with an increased risk of blood clots (lack of\u00a0protein\u00a0C,\u00a0protein\u00a0S, or antithrombin).<\/li><li>If you have or have had a disease caused by blood clots in the\u00a0arteries\u00a0are as\u00a0<strong>heart attack,\u00a0stroke<\/strong>\u00a0(stroke), or\u00a0<strong>angina.<\/strong><\/li><li>If you have or have had any\u00a0<strong>liver disease<\/strong>\u00a0and still have abnormal liver values.<\/li><li>If you have\u00a0<strong>porphyria,<\/strong>\u00a0a rare inherited blood disorder.<\/li><li>if you are\u00a0<strong>allergic<\/strong>\u00a0(<a href=\"https:\/\/zeepedia.com\/medical\/diseases\/peanut-allergy-and-nut-allergy\/\">hypersensitive<\/a>) or have <strong>side effects of estradiol,  norethisterone acetate,<\/strong>\u00a0or any of the other ingredients of Eviana (see section 6 \u201cContents of the pack and other information\u201d).<\/li><\/ul>\n\n\n\n<p>If any of the above affects you for the first time when you use Eviana, stop taking <span style=\"text-decoration: underline;\">Eviana 0.5 mg<\/span> and contact your doctor immediately.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings And Cautions<\/h2>\n\n\n\n<p>Talk to your doctor if you have or have had any of the following problems before starting treatment.\u00a0They may recur or worsen during treatment with Eviana.\u00a0Should this occur because of <em>side effects of estradiol<\/em>,  have more frequent check-ups with a doctor.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>If you have any disease affecting the lining of the uterus, as well as muscle knots (\u00a0fibroids\u00a0),\u00a0endometriosis,\u00a0or have had\u00a0endometrial hyperplasia\u00a0(severe thickening of the uterine lining).<\/li><li>If you have an increased risk of getting a blood clot (see below \u201cBlood clots in a vein (venous\u00a0thromboembolism\u00a0)\u201d)<\/li><li>If a close relative has had breast cancer or other estrogen-dependent cancer<\/li><li>High\u00a0blood pressure<\/li><li>Liver disease eg liver adenoma (benign\u00a0tumor\u00a0)<\/li><li>Diabetes<\/li><li>Gallstone disease<\/li><li>If you get a\u00a0migraine\u00a0or severe headache<\/li><li>If you have <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/sle\/\">systemic lupus erythematosus<\/a> (\u00a0<a href=\"https:\/\/zeepedia.com\/medical\/diseases\/sle\/\">SLE<\/a>\u00a0) &#8211; an\u00a0autoimmune\u00a0disease that affects many organs in the body<\/li><li>Epilepsy<\/li><li>Asthma<\/li><li>Otosclerosis (ossification of the middle ear leading to hearing loss)<\/li><li>Hypertriglyceridemia\u00a0(elevated blood lipids)<\/li><li>Fluid retention due to heart or kidney disease<\/li><li>Hypothyroidism\u00a0(the thyroid gland does not produce enough thyroid hormones) and you are treated with thyroid hormone<\/li><li>Hereditary\u00a0angioedema\u00a0(recurrent severe swelling), or if you have had occasional swelling of the hands, face, feet, lips, eyes, tongue, pharynx (obstruction of the respiratory tract), or digestive tract<\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/lactose-intolerance\/\">Lactose<\/a> intolerance.<\/li><\/ul>\n\n\n\n<p><strong>You should contact a doctor immediately and discontinue treatment with Eviana 0.5 mg<\/strong> <strong>if any of the following occur:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Some of what is mentioned in the section &#8220;Do not take Eviana 0.5 mg&#8221;<\/li><li>If skin or whites of the eyes turn yellow (jaundice);&nbsp;it may be a symptom of liver disease<\/li><li>If your&nbsp;blood pressure&nbsp;rises sharply (symptoms may include headache, fatigue, or dizziness)<\/li><li>If you are experiencing migraine-like headaches for the first time<\/li><li>If you become pregnant<\/li><li>If you get symptoms of a blood clot, such as:<ul><li>Painful swelling and redness of the legs<\/li><li>Sudden chest pain<\/li><li>Breathing difficulties.<\/li><\/ul><\/li><\/ul>\n\n\n\n<p>For more information, see below &#8220;Blood clots in a vein (venous&nbsp;thromboembolism&nbsp;)&#8221;.<br><\/p>\n\n\n\n<p><strong>Note:<\/strong>&nbsp;<strong>Eviana 0.5 mg <\/strong>is not a contraceptive.&nbsp;If it is less than 12 months since your last period, or if you are under 50, you may still need to use contraception to avoid pregnancy.&nbsp;Consult your doctor.<br><\/p>\n\n\n\n<p><strong>HRT&nbsp;and cancer<\/strong><\/p>\n\n\n\n<p><strong>Severe thickening of the uterine lining (&nbsp;endometrial hyperplasia&nbsp;) and cancer of the uterine lining (endometrial cancer)<\/strong><br><\/p>\n\n\n\n<p>The use of&nbsp;HRT&nbsp;with&nbsp;estrogen&nbsp;alone&nbsp;increases the risk of severe thickening of the uterine lining and cancer of the uterine lining.<br><\/p>\n\n\n\n<p>The&nbsp;progestogen in Eviana protects you against this extra risk.<br><\/p>\n\n\n\n<p><em>Comparison<\/em><\/p>\n\n\n\n<p>For women with the uterus left who do not take&nbsp;HRT, an average of 5 out of 1,000 women aged 50-65 will be diagnosed with endometrial cancer.<\/p>\n\n\n\n<p>For women aged 50\u201365 who have the uterus left and who take&nbsp;HRT&nbsp;with&nbsp;estrogen alone, 10\u201360 women out of 1,000 users will be diagnosed with endometrial cancer (ie between 5\u201355 extra cases) depending on&nbsp;dose&nbsp;one and how long it takes.<br><\/p>\n\n\n\n<p><strong>Irregular Bleeding<\/strong><\/p>\n\n\n\n<p>Irregular spotting or spotting may occur during the first 3-6 months of taking Eviana.&nbsp;But about the bleeding:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Lasts longer than 6 months<\/li><li>Begins after taking Eviana for 6 months<\/li><li>Continues after you stop taking Eviana<\/li><\/ul>\n\n\n\n<p>you should see a doctor as soon as possible.<br><\/p>\n\n\n\n<p><strong><a href=\"https:\/\/zeepedia.com\/diseases\/breast-cancer\/\">Breast Cancer<\/a><\/strong><\/p>\n\n\n\n<p>Data show that hormone replacement therapy (&nbsp;HRT&nbsp;) with a combination of&nbsp;estrogen-progestogen, or with&nbsp;estrogen&nbsp;alone, increases the risk of breast cancer.&nbsp;The increased risk depends on how long you use&nbsp;HRT.&nbsp;The increased risk is seen within 3 years.&nbsp;When treatment is stopped, the increased risk decreases over time, but it can persist for 10 years or more if you have used&nbsp;HRT&nbsp;for more than 5 years.<br><\/p>\n\n\n\n<p><em>Comparison<\/em><\/p>\n\n\n\n<p>For women aged 50 to 54 who do not take&nbsp;HRT, an average of 13 to 17 out of 1,000 will be diagnosed with breast cancer over a 5-year period.<\/p>\n\n\n\n<p>In women who are 50 years old and start taking&nbsp;HRT&nbsp;with&nbsp;estrogen&nbsp;alone&nbsp;for 5 years, 16-17 cases per 1,000 users (ie 0-3 extra cases) will occur.<\/p>\n\n\n\n<p>In women who are 50 years old and start taking&nbsp;HRT&nbsp;with&nbsp;estrogen-progestogen&nbsp;for 5 years, there will be 21 cases per 1,000 users (ie 4-8 extra cases).<br><\/p>\n\n\n\n<p>Among women aged 50\u201359 who do not use&nbsp;HRT, an average of 27 out of 1,000 will be diagnosed with breast cancer over a 10-year period.<\/p>\n\n\n\n<p>In women who are 50 years old and start taking&nbsp;HRT&nbsp;with&nbsp;estrogen&nbsp;alone&nbsp;for 10 years, 34 cases per 1,000 users (ie 7 extra cases) will occur.<\/p>\n\n\n\n<p>In women who are 50 years old and start taking&nbsp;HRT&nbsp;with&nbsp;estrogen-progestogen&nbsp;for 10 years, 48 \u200b\u200bcases per 1,000 users (ie 21 extra cases) will occur.<br><\/p>\n\n\n\n<p><strong>Check your breasts regularly.&nbsp;Contact a doctor if you notice changes such as:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Indentations or pits<\/li><li>Changes of the nipple<\/li><li>Nodules you can see or feel.<\/li><\/ul>\n\n\n\n<p>It is also recommended that you participate in a mammography examination when you are called to do so.\u00a0At the mammogram, you must tell the nurse\/healthcare professional doing the examination that you are using\u00a0HRT, as this medicine may increase the density of the breasts.\u00a0An increased density in the breasts can make it more difficult to detect lumps on mammography images.<br><\/p>\n\n\n\n<p><strong>Ovarian Cancer (&nbsp;ovarian cancer&nbsp;)<\/strong><\/p>\n\n\n\n<p>Ovarian cancer is rare &#8211; much rare than breast cancer.\u00a0Use of\u00a0HRT\u00a0with\u00a0estrogen\u00a0alone\u00a0or combined\u00a0estrogen-progestogen\u00a0has been associated with a slightly increased risk of ovarian cancer.<br><\/p>\n\n\n\n<p>The risk of ovarian cancer varies with age.\u00a0The diagnosis of ovarian cancer will, for example, be made on about 2 women out of 2000 aged 50 to 54 who do not take\u00a0HRT for a 5-year period.\u00a0For women who have taken\u00a0HRT\u00a0for 5 years, there will be about 3 cases per 2000 users (ie about 1 extra case).<\/p>\n\n\n\n<p><strong>How\u00a0HRT\u00a0affects the heart and blood circulation<\/strong><\/p>\n\n\n\n<p><strong>Blood clots in a vein (venous&nbsp;thromboembolism&nbsp;)<\/strong><\/p>\n\n\n\n<p>The risk of&nbsp;<strong>blood clots in the veins<\/strong>&nbsp;is 1.3\u20133 times higher for women who take&nbsp;HRT than for those who do not, especially during the first year of treatment.<\/p>\n\n\n\n<p>Blood clots can be serious.&nbsp;If a blood clot ends up in the lungs, it can cause chest pain, shortness of breath, collapse or even lead to death.<\/p>\n\n\n\n<p>You are more likely to get a blood clot in a vein if any of the following apply to you.&nbsp;Tell your doctor if any of the following apply to you:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>You have not been able to walk or stand for a long time due to a major operation, injury or illness (see also section 3, \u201cIf you need surgery\u201d)<\/li><li>You are severely overweight (&nbsp;BMI&nbsp;over 30 kg \/ m&nbsp;<sup>2<\/sup>&nbsp;)<\/li><li>You have a coagulation disorder that requires long-term treatment with drugs that prevent blood clots<\/li><li>If a close relative has had a blood clot in the bone, lung, or another organ<\/li><li>You have&nbsp;SLE&nbsp;(systemic lupus erythematosus)<\/li><li>You have cancer.<\/li><\/ul>\n\n\n\n<p>The symptoms of blood clots are described in the section &#8220;You should contact a doctor immediately and discontinue treatment with Eviana&#8221;.<br><\/p>\n\n\n\n<p><em>Comparison<\/em><\/p>\n\n\n\n<p>For women in their 50s who do not take&nbsp;HRT, an average of 4-7 out of 1,000 are expected to have a blood clot in a vein over a 5-year period.<\/p>\n\n\n\n<p>For women in their 50s who have taken&nbsp;HRT&nbsp;with&nbsp;estrogen-progestogen&nbsp;for more than 5 years, 9-12 out of 1,000 users are expected to get a blood clot in a vein (ie 5 extra cases).<br><\/p>\n\n\n\n<p><strong>Heart disease (heart attack)<\/strong><\/p>\n\n\n\n<p>There is no evidence that&nbsp;HRT&nbsp;prevents heart attacks.&nbsp;For women over the age of 60 who take&nbsp;HRT&nbsp;with&nbsp;estrogen-progestin, the risk of developing heart disease is slightly higher than for those who do not take&nbsp;HRT.<br><\/p>\n\n\n\n<p><strong>Stroke&nbsp;(apoplexy)<\/strong><\/p>\n\n\n\n<p>The risk of&nbsp;stroke&nbsp;is about 1.5 times higher for those who take&nbsp;HRT&nbsp;compared to those who do not.&nbsp;The risk of&nbsp;stroke&nbsp;is age-dependent, therefore the number of cases of&nbsp;stroke&nbsp;increases&nbsp;due to the use of&nbsp;HRT&nbsp;with increasing age.<br><\/p>\n\n\n\n<p><em>Comparison<\/em><\/p>\n\n\n\n<p>For women in their 50s who do not take&nbsp;HRT, an average of 8 out of 1,000 people is expected to have a&nbsp;stroke&nbsp;over a 5-year period.<\/p>\n\n\n\n<p>For women in their 50s who take&nbsp;HRT&nbsp;for more than 5 years, 11 out of 1,000 users are expected to have a&nbsp;stroke&nbsp;(ie 3 extra cases).<br><\/p>\n\n\n\n<p><strong>Other conditions<\/strong><\/p>\n\n\n\n<p>The use of&nbsp;HRT&nbsp;preparations does not prevent memory loss.&nbsp;The risk of memory loss may be slightly higher in women who start using&nbsp;HRT&nbsp;after the age of 65.&nbsp;Consult your doctor.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other Drugs And Eviana<\/h2>\n\n\n\n<p>Some medicines may affect the way <strong>Eviana 0.5 mg<\/strong> works, which may lead to irregular bleeding.&nbsp;The following applies:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Drugs for&nbsp;<strong>epilepsy<\/strong>&nbsp;(eg phenobarbital,&nbsp;phenytoin,&nbsp;and carbamazepine)<\/li><li>Medicines for&nbsp;<strong>tuberculosis<\/strong>&nbsp;(eg rifampicin and rifabutin)<\/li><li>Drugs for&nbsp;<strong>HIV&nbsp;&#8211;&nbsp;infection<\/strong>&nbsp;(for example, nevirapine, efavirenz, ritonavir, and nelfinavir)<\/li><li>Medicines for&nbsp;<strong>hepatitis&nbsp;C&nbsp;infection&nbsp;s<\/strong>&nbsp;(such as telaprevir)<\/li><li>An herbal medicine containing&nbsp;<strong>St. John&#8217;s wort<\/strong>&nbsp;(&nbsp;<em>Hypericum perforatum<\/em>&nbsp;).<\/li><\/ul>\n\n\n\n<p>Other medicines may increase the effect of Eviana:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Medicines containing&nbsp;<strong>ketoconazole<\/strong>&nbsp;(medicines used to treat fungal infections).<\/li><\/ul>\n\n\n\n<p><em>Eviana 0.5 mg<\/em> may affect cyclosporine when used concomitantly.<br><\/p>\n\n\n\n<p>Tell&nbsp;your&nbsp;doctor or pharmacist&nbsp;if you are taking or have recently taken any other medicines, including medicines obtained without a prescription and herbal remedies.<br><\/p>\n\n\n\n<p><strong>Results from blood tests analyze<\/strong><\/p>\n\n\n\n<p>If you need to take a blood sample, tell your doctor or the person taking the blood sample that you are taking Eviana as it may affect the results of some tests.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Eviana With Food And Drink<\/h2>\n\n\n\n<p>The tablets can be taken with or without food and drink.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy And Breastfeeding<\/h2>\n\n\n\n<p><strong>Pregnancy:<\/strong>&nbsp;Eviana is for women who have stopped menstruating.&nbsp;If you become pregnant, stop taking Eviana and consult a doctor.<br><\/p>\n\n\n\n<p><strong>Breast-feeding:<\/strong>&nbsp;You should not take Eviana if you are breast-feeding.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p><strong>Eviana 0.5 mg<\/strong> has no known influence on the ability to drive or use machines.<br><\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.\u00a0One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or\u00a0side effects.\u00a0Descriptions of <strong>Eviana side effects<\/strong> and\u00a0its side effects\u00a0can be found in other sections.<\/p>\n\n\n\n<p>&nbsp;Read all the information in this leaflet for guidance.&nbsp;If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Important Information About A Substance In Eviana<\/h2>\n\n\n\n<p>Eviana contains&nbsp;lactose monohydrate.&nbsp;If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking Eviana.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. How To Take Eviana<\/h2>\n\n\n\n<p>Always take this medicine exactly as your doctor has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<br><\/p>\n\n\n\n<p><strong>Take one tablet daily at about the same time.&nbsp;<\/strong>Take the tablet with a glass of water.<br><\/p>\n\n\n\n<p><strong>Take one tablet daily without interruption.&nbsp;<\/strong>When you have used up all 28 tablets in&nbsp;calendar&nbsp;pack one, continue immediately with the next pack.<br><\/p>\n\n\n\n<p>For further information on how to use&nbsp;calendar&nbsp;packaging, see INSTRUCTIONS FOR USE at the end of the package leaflet.<br><\/p>\n\n\n\n<p>You can&nbsp;start treatment with<strong> Eviana<\/strong> <strong>0.5 mg<\/strong>&nbsp;on any day.&nbsp;However, if you switch from an&nbsp;HRT&nbsp;preparation when you have your monthly bleeding, you should start treatment immediately after the bleeding has stopped.<br><\/p>\n\n\n\n<p>Your doctor will strive to\u00a0give you\u00a0the lowest\u00a0dose, which will give you relief of symptoms, and you should use Eviana for the shortest possible time.\u00a0Talk to your doctor if you do not get any relief from the symptoms, or feel that the\u00a0dose\u00a0is too high.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If You Take More Eviana 0.5 mg Then You Should<\/h2>\n\n\n\n<p>If you have ingested too much medicine or if, for example, a child has accidentally ingested the medicine, contact a doctor, hospital, or the Poison Information Center for risk assessment and advice.&nbsp;<\/p>\n\n\n\n<p><strong>An overdose of&nbsp;estrogen&nbsp;can cause <\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Chest tightness<\/li><li>Nausea<\/li><li>Vomiting <\/li><li>Irregular vaginal bleeding (&nbsp;metrorrhagia&nbsp;).&nbsp;<\/li><\/ul>\n\n\n\n<p><strong>Overdose of&nbsp;progestogens&nbsp;can lead to <\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Depression<\/li><li>Fatigue<\/li><li>Acne<\/li><li>Heavy hair growth on the face and body (&nbsp;hirsutism&nbsp;).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">If You Forget To Take Eviana<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>If you forget to take your tablet, you should take it within 12 hours from the usual time.&nbsp;If more than 12 hours have passed, take the next tablet, as usual, the next day.<\/li><li>Do not take a double&nbsp;dose&nbsp;to make up for a tablet you forgot to take.<\/li><li>Missing a&nbsp;dose&nbsp;can increase the likelihood of breakthrough bleeding and spotting unless you have had your uterus operated on.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">If You Stop Taking Eviana<\/h2>\n\n\n\n<p>If you want to stop taking Eviana, first discuss this with your doctor.\u00a0The doctor will explain what it means to stop taking the tablets and inform you about other alternatives.<\/p>\n\n\n\n<p>If you have any further questions about the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<p><strong>If you need surgery<\/strong><\/p>\n\n\n\n<p>If you are going to have surgery, tell your surgeon that you are taking Eviana.&nbsp;You may need to stop taking Eviana 0.5 mg for 4 to 6 weeks before surgery to avoid the risk of blood clots (see section 2, \u201cBlood clots in a vein (venous&nbsp;thromboembolism&nbsp;)\u201d).&nbsp;Ask your doctor when it is appropriate to start taking Eviana again.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible Eviana Side Effects<\/h2>\n\n\n\n<p>Eviana Side Effects<\/p>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects,&nbsp;although not everybody gets them.<br><\/p>\n\n\n\n<p>The following diseases are more common in women who take&nbsp;HRT&nbsp;than those who do not:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Breast cancer<\/li><li>Severe thickening of the uterine lining (&nbsp;endometrial hyperplasia&nbsp;) or cancer of the uterine lining (endometrial cancer)<\/li><li>Ovarian cancer (&nbsp;ovarian cancer&nbsp;)<\/li><li>Blood clots in veins in bones or lungs (venous&nbsp;thromboembolism&nbsp;)<\/li><li>Heart disease<\/li><li>Stroke&nbsp;(apoplexy)<\/li><li>Probable memory loss, if treatment with&nbsp;HRT is&nbsp;started after the age of 65.<\/li><\/ul>\n\n\n\n<p>See section 2 \u201cWhat you need to know before you take Eviana\u201d for more information on these&nbsp;<em>Eviana side effects<\/em><br><\/p>\n\n\n\n<p><strong>Very common<em> Eviana 0.5 mg<\/em>&nbsp;side effects&nbsp;(may affect more than 1 user in 10)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Vaginal bleeding<\/li><\/ul>\n\n\n\n<p><strong>Common&nbsp;Eviana side effects&nbsp;(may affect up to 1 in 10 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Fungal infection of the abdomen or&nbsp;inflammation&nbsp;of the vagina<\/li><li>The vigorous growth of the uterine lining (&nbsp;endometrial hyperplasia&nbsp;)<\/li><li>Nausea<\/li><li>Abdominal pain<\/li><li>Back or neck pain<\/li><li>Pain in arms or legs<\/li><li>Headache.<\/li><\/ul>\n\n\n\n<p><strong>Uncommon&nbsp;side effects&nbsp;(may affect up to 1 in 100 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Allergic reaction&nbsp;(hypersensitivity)<\/li><li>Depression or worsening of current depression<\/li><li>Nervousness<\/li><li>Dizziness<\/li><li>Migraine&nbsp;(See &#8220;You should contact your doctor immediately and stop taking Eviana&#8221; in section 2)<\/li><li>Pain or discomfort in the breasts<\/li><li>Tension or another discomfort in the stomach<\/li><li>Weight gain due to accumulation of fluid in the body<\/li><li>Swollen arms and legs (peripheral&nbsp;edema&nbsp;)<\/li><li>Leg cramps<\/li><li>Poor digestion (&nbsp;dyspepsia&nbsp;)<\/li><li>Acne<\/li><li>Hair loss<\/li><li>Itching&nbsp;or&nbsp;hives.<\/li><\/ul>\n\n\n\n<p><strong>Very rare&nbsp;side effects&nbsp;(may affect up to 1 in 10,000 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>General&nbsp;hypersensitivity reactions&nbsp;(eg anaphylactic reaction\/shock) have been reported.<\/li><\/ul>\n\n\n\n<p><strong>Other&nbsp;<span style=\"text-decoration: underline;\">Eviana side effects<\/span>&nbsp;are&nbsp;HRT&nbsp;combination drugs<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>The disease of the gallbladder<\/li><li>Various skin diseases:<ul><li>Dark skin spots, especially on the face and neck, so-called &#8220;pregnancy spots&#8221; (chloasma)<\/li><li>Painful reddish-purple bumps on the skin (erythema nodosum)<\/li><li>Annular redness or sore rash (erythema multiforme)<\/li><li>Red or purple discolorations on the skin and\/or mucous membranes (&nbsp;vascular&nbsp;purpura)<\/li><\/ul><\/li><li>Dry eyes<\/li><li>Changes in the tear film composition.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">5. How To Store Eviana<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Keep this medicine out of sight and reach of children.<\/li><li>Do not use this medicine after the expiry date which is stated on the label and the outer carton after \u201cEXP\u201d.\u00a0The expiration date is the last day of the specified month.<\/li><li>Do not store above 25 \u00b0 C.\u00a0Store in a cold place.<\/li><li>Store in the outer carton.\u00a0Sensitive to light.<\/li><li>Medicines should not be disposed of via wastewater or household waste.\u00a0Ask your pharmacist how to dispose of medicines no longer required.\u00a0These measures will help to protect the environment.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents Of The Packaging And Other Information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content Declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substances are estradiol and norethisterone acetate.\u00a0Each tablet contains 0.5 mg estradiol (as hemihydrate) and 0.1 mg norethisterone acetate.<\/li><li>The other ingredients are\u00a0lactose monohydrate, corn starch, hydroxypropyl cellulose, magnesium stearate, hypromellose, triacetin, and talc.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What The Medicine Looks Like And The Contents Of The Pack<\/h2>\n\n\n\n<p>The film-coated tablets are white and round with a diameter of 6 mm.&nbsp;The tablets are marked NOVO 291 on one side and have a Novo Nordisk logo (Apistjur) on the other.<br><\/p>\n\n\n\n<p>Pack sizes:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>28 film-coated tablets<\/li><li>3 x 28 film-coated tablets<\/li><\/ul>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder And Manufacturer<\/h2>\n\n\n\n<p>Novo Nordisk A \/ S<\/p>\n\n\n\n<p>Novo All\u00e9<\/p>\n\n\n\n<p>DK-2880 Bagsv\u00e6rd<\/p>\n\n\n\n<p>Denmark<br><\/p>\n\n\n\n<p>This medicinal product is authorized under the European Economic Area under the names:<\/p>\n\n\n\n<p>Activelle: Austria, Italy, Portugal<\/p>\n\n\n\n<p>Activelle low: Denmark, Iceland, Italy<\/p>\n\n\n\n<p>Minor activities: Belgium, Luxembourg<\/p>\n\n\n\n<p>Eviana: Estonia, Hungary, the Netherlands, Norway, Spain,<\/p>\n\n\n\n<p>Noviana: Finland<br><\/p>\n","protected":false},"excerpt":{"rendered":"<p> Eviana is a combined Hormone Replacement Therapy (HRT). It is used in postmenopausal females for 1 year as their last natural period\u2014Eviana relives of signs occurring after menopause.<\/p>\n","protected":false},"author":2,"featured_media":27922,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"yes","footnotes":""},"categories":[2205,2200],"tags":[3093,3095,3096,3094,3433,3435,3436,3434,2212,2210],"class_list":["post-8514","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-e","category-medicines","tag-estradiol","tag-estradiol-dose","tag-estradiol-side-effects","tag-estradiol-uses","tag-eviana","tag-eviana-dose","tag-eviana-side-effects","tag-eviana-uses","tag-medicine","tag-tablet"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8514","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=8514"}],"version-history":[{"count":61,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8514\/revisions"}],"predecessor-version":[{"id":27925,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8514\/revisions\/27925"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media\/27922"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=8514"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=8514"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=8514"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}