{"id":8506,"date":"2021-03-13T09:06:57","date_gmt":"2021-03-13T09:06:57","guid":{"rendered":"https:\/\/zeepedia.com\/?p=8506"},"modified":"2023-01-02T18:24:08","modified_gmt":"2023-01-02T18:24:08","slug":"eusaprim","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/eusaprim\/","title":{"rendered":"Eusaprim &#8211; Sulfamethoxazole Uses, Dose And Side Effects"},"content":{"rendered":"\n<p><strong>Eusaprim 16 mg\/ml + 80 mg\/ml concentrate for solution for infusion\u00a0trimethoprim + sulfamethoxazole<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What Eusaprim Is And What Eusaprim Used For<\/h2>\n\n\n\n<p>Eusaprim 16 mg\/ml + 80 mg\/ml concentrate for\u00a0solution\u00a0for\u00a0infusion\u00a0(called &#8220;Eusaprim&#8221; in this leaflet) is a combination of two different\u00a0antibiotics\u00a0called sulfamethoxazole and trimethoprim.\u00a0It is used to treat\u00a0infections\u00a0caused by bacteria.\u00a0This drug combination is also called co-trimoxazole.\u00a0Like all\u00a0antibiotics, Eusaprim only works against certain types of bacteria.\u00a0This means that it is only suitable for treating certain types of\u00a0infection.<\/p>\n\n\n\n<p>Eusaprim can be used to treat or prevent the following:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Lung infections (\u00a0pneumonia\u00a0or\u00a0<em>Pneumocystis jirovecii<\/em>\u00a0&#8211;\u00a0pneumonia\u00a0) caused by a\u00a0bacterium\u00a0called\u00a0<em>Pneumocystis jirovecii<\/em><\/li><li>Infection\u00a0is caused by a\u00a0bacterium\u00a0called Toxoplasma (toxoplasmosis).<\/li><\/ul>\n\n\n\n<p>Eusaprim can be used to treat:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Bladder or urinary tract infections<\/li><li>An\u00a0infection\u00a0called nocardiosis that can affect the lungs, skin, and brain.<\/li><li>Eusaprim\u00a0infusion\u00a0is usually only given to you if you cannot take medicines by mouth.<\/li><li>Eusaprim concentrate for\u00a0solution\u00a0for\u00a0infusion\u00a0is intended for children from 6 weeks of age and adults (> 18 years).<\/li><\/ul>\n\n\n\n<p>The account should be taken of official guidelines regarding the appropriate use of\u00a0antibacterial\u00a0agents.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2. What You Need To Know Before Using Eusaprim<\/h2>\n\n\n\n<p>It would help if you were not given Eusaprim:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>If you are allergic (<a href=\"https:\/\/zeepedia.com\/medical\/diseases\/peanut-allergy-and-nut-allergy\/\">hypersensitive<\/a>) to sulfamethoxazole, trimethoprim, cotrimoxazole, or any of the other ingredients of Eusaprim (see section 6: Contents of the pack and other information)<\/li><li>If you are allergic to sulfonamide medicines.\u00a0Such drugs may be sulphonylureas (eg glyclazide and glibenclamide) or thiazide diuretics (eg bendroflumethiazide &#8211; a diuretic tablet)<\/li><li>If you have severe renal impairment<\/li><li>If you have severe hepatic impairment<\/li><li>If you have ever had problems with your blood that have caused bruising and bleeding (\u00a0thrombocytopenia\u00a0)<\/li><li>If you have ever been told that you have a rare blood problem called\u00a0porphyria, which can affect your skin or nervous system.<\/li><li>Eusaprim should not be given to infants during the first 6 weeks of life.<\/li><li>If you are unsure if any of the above applies to you, talk to your doctor or pharmacist before taking Eusaprim.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings And Cautions<\/h2>\n\n\n\n<p>Talk to your doctor, pharmacist, or nurse before receiving Eusaprim:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>You must seek medical attention immediately if you develop a rash during treatment.\u00a0Rash that may be life-threatening (\u00a0Stevens-Johnson syndrome,\u00a0toxic epidermal necrolysis,\u00a0and drug-induced rash with\u00a0eosinophilia\u00a0and systemic symptoms) have been reported using sulfamethoxazole and trimethoprim.\u00a0See section 4 for more information on symptoms.<\/li><li>At the beginning of treatment, generalized blushing with blisters and <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/cold\/\">fever<\/a> should raise suspicion of a serious reaction called\u00a0acute generalized exanthematous\u00a0pustulosis\u00a0(AGEP) (see section 4).<\/li><li>If you have severe\u00a0allergies\u00a0or severe\u00a0asthma<\/li><li>If you have kidney disease<\/li><li>If you have been told that you are at risk for a rare blood disorder called\u00a0porphyria\u00a0that can affect your skin or nervous system<\/li><li>If you do not have enough\u00a0folic acid\u00a0(a\u00a0vitamin\u00a0) in your body, it can make your skin pale and make you feel tired, weak, and short of breath.\u00a0This is called\u00a0anaemia.<\/li><li>If you have a condition called\u00a0glucose\u00a0-6-phosphate dehydrogenase deficiency, which may cause jaundice or spontaneous\u00a0red blood cell\u00a0breakdown<\/li><li>If you have a metabolic problem called phenylketonuria and are not on a special diet to improve your condition<\/li><li>If you are older<\/li><li>If your doctor has told you that you have a lot of\u00a0potassium\u00a0in\u00a0your\u00a0blood<\/li><li>If you are underweight or malnourished<\/li><li>If you have a severe blood disorder, such as low\u00a0red blood cell count\u00a0(anaemia), low\u00a0white blood cell count\u00a0(\u00a0leukopenia\u00a0), or low\u00a0platelet count, which may cause bleeding and bruising (\u00a0thrombocytopenia\u00a0).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Other Medicines And Eusaprim<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.\u00a0The reason is that Eusaprim may affect how some other medicines work, and some other medicines may affect how Eusaprim works.<\/p>\n\n\n\n<p>In particular, tell your doctor or pharmacist if you are taking any of the following medicines:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Diuretics\u00a0(\u00a0diuretic\u00a0tablets) that can increase the amount of urine you produce<\/li><li>Pyrimethamine used to treat and prevent\u00a0malaria\u00a0and to treat diarrhoea<\/li><li>Ciclosporin used after organ transplants<\/li><li>Blood-thinning drugs such as\u00a0warfarin<\/li><li>Phenytoin\u00a0is used to treat\u00a0epilepsy\u00a0(seizures)<\/li><li>Drugs for the treatment of\u00a0diabetes, e.g.\u00a0<ul><li>Glibenclamide<\/li><li>Glipizide<\/li><li>Tolbutamide (sulphonylureas)<\/li><li>Repaglinide<\/li><\/ul><\/li><li>Drugs to treat heart problems, e.g.\u00a0digoxin\u00a0or\u00a0procainamide<\/li><li>Amantadine is used to treat\u00a0Parkinson&#8217;s disease,\u00a0multiple sclerosis,\u00a0influenza,\u00a0or\u00a0shingles<\/li><li>Medicines to treat\u00a0HIV\u00a0(human immunodeficiency virus), called zidovudine or lamivudine<\/li><li>Drugs that can increase the amount of\u00a0potassium\u00a0in the blood, e.g.\u00a0diuretics\u00a0(\u00a0diuretic\u00a0tablets such as\u00a0spironolactone, which helps increase the amount of urine you produce) or\u00a0ACE inhibitors\u00a0(can be used to treat high\u00a0blood pressure\u00a0or certain heart problems)<\/li><li>Azathioprine, which can be used in patients after organ transplantation or for the treatment of disorders of the immune system or inflammatory bowel diseases<\/li><li>Methotrexate is a medicine used to treat certain cancers or certain diseases that affect the immune system<\/li><li>Rifampicin which is an\u00a0antibiotic<\/li><li>Folic acid.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy And Breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.\u00a0Eusaprim should not be used during pregnancy, especially during the first 3 months, unless necessary.\u00a0If breastfeeding, you should avoid Eusaprim as your baby would be at increased risk of jaundice.<\/p>\n\n\n\n<p>See the next section for more information on the medicine&#8217;s&nbsp;ethanol&nbsp;content.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving And Using Machines<\/h2>\n\n\n\n<p>Some patients have experienced dizziness or fainting when using Eusaprim.&nbsp;Do not drive or use machines if you experience these&nbsp;side effects.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Eusaprim contains<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Sodium metabisulfite.\u00a0This can lead to allergic reactions, e.g.\u00a0rash, swelling of the eyelids, face, or lips, or difficulty breathing.\u00a0These reactions are rare, but the risk of being affected may be greater if you suffer from\u00a0allergies\u00a0or\u00a0asthma.<\/li><li>13.2% by volume of\u00a0ethanol\u00a0(alcohol).\u00a0It can be up to 521 mg per\u00a0dose, equivalent to 13.2 ml of beer or 5.5 ml of wine.\u00a0This can be harmful if you are an alcoholic.\u00a0You should also consider the ethanol content if you are pregnant or breastfeeding, have a baby, or have liver problems or\u00a0epilepsy.<\/li><li>1.7 mmol (or 38.87 mg)\u00a0sodium.\u00a0This should be considered for patients prescribed a low-salt diet.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How To Use Eusaprim<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>You are never expected to give yourself this medicine.\u00a0It is always given by trained staff.<\/li><li>Eusaprim is given as a\u00a0continuous\u00a0infusion\u00a0into a vein.\u00a0This happens slowly over a while.<\/li><li>Before you receive the medicine, it will be diluted.<\/li><\/ul>\n\n\n\n<p>What\u00a0you receive and how often you receive a\u00a0dose\u00a0depends on the following:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>What type of\u00a0infection\u00a0do you have<\/li><li>Severity of infection<\/li><li>Your weight<\/li><li>Your age<\/li><\/ul>\n\n\n\n<p>Dosage<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Norm Aldo Recommendations for acute\u00a0infections<\/li><\/ul>\n\n\n\n<p><em>Adults (&gt; 18 years)<\/em><\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong>Age<\/strong><\/td><td><strong>Dose<\/strong><\/td><\/tr><tr><td>Adults (&gt; 18 years)<\/td><td>2&nbsp;ampoules&nbsp;(5 ml) morning and evening.&nbsp;The maximum&nbsp;dose&nbsp;is 3&nbsp;ampoules&nbsp;(5 ml) of Eusaprim morning and evening.<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p>The usual dose for children is approximately 6 mg trimethoprim and 30 mg sulfamethoxazole per kg body weight per day, divided into two equal&nbsp;doses.&nbsp;The schedule for children corresponds to the child&#8217;s age and body weight according to the table below:<br><\/p>\n\n\n\n<p><em>Children 12-18 years how<\/em><\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong>Age<\/strong><\/td><td><strong>Dose<\/strong><\/td><\/tr><tr><td>Children 12-18 years<\/td><td>2&nbsp;ampoules&nbsp;(5 ml) morning and evening.&nbsp;The maximum&nbsp;dose&nbsp;is 3&nbsp;ampoules&nbsp;(5 ml) of Eusaprim morning and evening.<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p><em>Children from 6 weeks up to 12 years of age<\/em><\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong>Age<\/strong><\/td><td><strong>Dose<\/strong><\/td><\/tr><tr><td>Children from 6 weeks up to 6 months<\/td><td>1.25 ml morning and evening<\/td><\/tr><tr><td>Children from 6 months up to 6 years<\/td><td>2.5 ml morning and evening<\/td><\/tr><tr><td>Children 6-12 years<\/td><td>5 ml morning and evening<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n<p>The infusion\u00a0lasts about 1\u20131.5 hours, balanced against your fluid needs.<\/p>\n\n\n\n<p>If you have kidney problems, your doctor may<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Prescribe\u00a0a lower\u00a0dose\u00a0of Eusaprim<\/li><li>Take blood samples to check if the medicine is working properly.<\/li><\/ul>\n\n\n\n<p>If you have been taking Eusaprim for a long time, your doctor may<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Take blood samples to test if the medicine works properly<\/li><li>Prescribe\u00a0folic acid\u00a0(a\u00a0vitamin\u00a0) that you should take at the same time as Eusaprim.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">If You Take More Eusaprim Then, You Should<\/h2>\n\n\n\n<p>If you have been given too much Eusaprim, contact your doctor or nurse immediately.<\/p>\n\n\n\n<p>If you think you have been given too much Eusaprim, you can:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Feel nauseous or vomit<\/li><li>Feel dizzy or confused<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible Eusaprim Side Effects<\/h2>\n\n\n\n<p>This medicine can cause side effects like all medicines, although not everybody gets them.<\/p>\n\n\n\n<p>You may experience the following\u00a0side effects\u00a0with this medicine.<\/p>\n\n\n\n<p>Contact a doctor immediately if you have an\u00a0allergic reaction.\u00a0The risk of an\u00a0allergic reaction\u00a0is very low (less than 1 in 10,000 people are affected).\u00a0Signs of an\u00a0allergic reaction\u00a0include:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Allergic reactions<\/li><li>Difficulty breathing<\/li><li>Fainting<\/li><li>Swelling of the face<\/li><li>Swelling of the mouth, tongue, or throat may become red and painful and lead to difficulty swallowing.<\/li><li>Chest <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/brain-and-nerves\/pain\/\">pain<\/a><\/li><li>Red spots on the skin<\/li><\/ul>\n\n\n\n<p>You must seek medical attention immediately if you develop a rash during treatment.\u00a0Rash that may be life-threatening (\u00a0Stevens-Johnson syndrome,\u00a0toxic epidermal necrolysis,\u00a0and drug-induced rash with\u00a0eosinophilia\u00a0and systemic symptoms) has been reported with sulfamethoxazole and trimethoprim.\u00a0It can start as reddish-purple, target-like spots or round spots with blisters in the middle, often symmetrically distributed on the body.\u00a0These skin reactions, which can be life-threatening, often occur along with\u00a0flu-like symptoms.\u00a0The rash can develop into widespread blistering or flaking of the skin.\u00a0Additional signs of being aware of are sores in the mouth, throat, nose, or genitals or\u00a0conjunctivitis(red and swollen eyes).\u00a0If you get a rash or signs of these skin reactions, stop taking Eusaprim immediately, seek emergency medical advice and tell your doctor that you are taking this medicine.<\/p>\n\n\n\n<p>Get Stevens-Johnson syndrome, toxic epidermal necrolysis, or drug-induced rash with eosinophilia and systemic symptoms after using sulfamethoxazole and trimethoprim, which are found in Eusaprim. You can never use drugs containing sulfamethoxazole or trimethoprim again.<\/p>\n\n\n\n<p>The greatest risk of serious skin reactions is within the first few weeks of treatment.<\/p>\n\n\n\n<p><strong><em>Other\u00a0side effects\u00a0include:<\/em><\/strong><\/p>\n\n\n\n<p><strong>Very common Eusaprim side effects (more than 1 in 10 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>High potassium levels\u00a0in the blood can lead to abnormal heartbeats (\u00a0palpitations\u00a0).<\/li><\/ul>\n\n\n\n<p><strong>Regular (less than 1 in 10 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>A fungal infection called cod or\u00a0candida\u00a0can affect the mouth or vagina<\/li><li>Headache<\/li><li>Nausea<\/li><li>Diarrhoea<\/li><li>Rash<\/li><\/ul>\n\n\n\n<p><strong>Uncommon (less than 1 in 100 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Vomiting<\/li><\/ul>\n\n\n\n<p><strong>Very rare (less than 1 in 10,000 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>High fever or recurrent\u00a0infections<\/li><li>Wheezing or difficulty breathing<\/li><li>A potentially life-threatening rash (\u00a0Stevens-Johnson syndrome,\u00a0toxic epidermal necrolysis\u00a0) has been reported (see Warnings and Precautions)<\/li><li>Very rare cases of generalized\u00a0redness\u00a0of the whole body (\u00a0acute\u00a0generalized exanthematous\u00a0pustulosis\u00a0(AGEP)) (see section 2)<\/li><li>Sores in the mouth, <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/cold\/\">cold<\/a> sores and sores or soreness on the tongue<\/li><li>Lumps of skin or\u00a0hives\u00a0(raised, red or white, itchy spots on the skin)<\/li><li>Blisters on the skin or in the mouth, nose, vagina, or tail<\/li><li>Inflammation\u00a0of the eye leads to pain and\u00a0redness<\/li><li>Rash or sun damage when you have been out (even on cloudy days)<\/li><li>Low levels of\u00a0sodium\u00a0in the blood<\/li><li>Changed blood levels<\/li><li>Feeling weak, tired or listless, pale skin (anaemia)<\/li><li>Heart problems<\/li><li>Jaundice (skin or whites of the eyes turn yellow).\u00a0This can occur at the same time as unexpected bleeding or a bruise.<\/li><li>Abdominal pain, which may occur with blood in the stool<\/li><li>Pain in the chest, muscles or joints and muscle weakness<\/li><li>Arthritis<\/li><li>Urinary problems.\u00a0Difficulty urinating.\u00a0You urinate more or less than usual.\u00a0Blood in the urine or cloudy urine<\/li><li>Kidney problems<\/li><li>Sudden headache or stiffness in the neck, accompanied by fever<\/li><li>Problems controlling movements<\/li><li>Seizures (convulsions or seizures)<\/li><li>Instability or dizziness<\/li><li>Ringing or unusual sounds in the ears<\/li><li>Tingling or numbness in the hands or feet<\/li><li>You get strange or unusual visions (hallucinations)<\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/depression\/\">Depression<\/a><\/li><li>Muscle pain or muscle weakness in\u00a0HIV\u00a0patients<\/li><li>Loss of appetite<\/li><\/ul>\n\n\n\n<p><strong>Has been reported (occurs in an unknown number of users)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Psychotic states (mental states that can cause you to lose touch with reality)<\/li><li>Drug-induced rash with\u00a0eosinophilia\u00a0and systemic symptoms (a type of\u00a0allergic reaction\u00a0that can cause fever, rash, and abnormal results on blood tests and liver function tests [may be a sign of multiple organ failure])<\/li><li>Plum-colored raised and painful sores on limbs and sometimes on the face and neck, along with fever (Sweet&#8217;s syndrome).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">5. How To Store Eusaprim<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Keep this medicine out of sight and reach of children<\/li><li>Protect from heat and direct sunlight.<\/li><li>Use before the expiry date, which is stated on the carton and label.<\/li><li>Store in the original package together with the package leaflet.<\/li><\/ul>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.\u00a0Ask your pharmacist how to dispose of medicines that are no longer required.\u00a0These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents Of The Packaging And Other Information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content Declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li> The active substances are sulfamethoxazole and trimethoprim.\u00a0This combination of drugs is sometimes called cotrimoxazole.\u00a05 ml Eusaprim contains 400 mg sulfamethoxazole and 80 mg trimethoprim.<\/li><li>The other ingredients are:<ul><li>Propylene glycol (E1520)<\/li><li>Tromethamine<\/li><li>Sodium hydroxide (E524)<\/li><li>Sodium metabisulfite (E223)<\/li><li>Ethanol<\/li><li>Water for\u00a0injection<\/li><\/ul><\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What The Medicine Looks Like And The Contents Of The Pack<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Eusaprim 16 mg \/ ml + 80 mg \/ ml concentrate for\u00a0solution\u00a0for\u00a0infusion\u00a0in a\u00a05 ml\u00a0glass ampoule\u00a0.<\/li><li>Each\u00a05 ml\u00a0ampoule\u00a0contains 400 mg of sulfamethoxazole and 80 mg of trimethoprim.<\/li><li>The ampoules\u00a0are delivered in packs of 10 pcs.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder And Manufacturer<\/h2>\n\n\n\n<p>Marketing Authorisation Holder:<\/p>\n\n\n\n<p>Aspen Pharma Trading Limited<\/p>\n\n\n\n<p>3016 Lake Drive,<\/p>\n\n\n\n<p>Citywest Business Campus,<\/p>\n\n\n\n<p>Dublin 24, Ireland<\/p>\n\n\n\n<p>Manufacturer:<\/p>\n\n\n\n<p>Aspen Bad Oldesloe GmbH, Industriestrasse 32-36,<\/p>\n\n\n\n<p>D-23843 Bad Oldesloe<\/p>\n\n\n\n<p>Germany<br><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Eusaprim in the cure of diarrhoea and jejunal infections.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2205,2200],"tags":[3474,3476,3477,3475,2235,2212,3453,3455,3456,3454],"class_list":["post-8506","post","type-post","status-publish","format-standard","hentry","category-e","category-medicines","tag-eusaprim","tag-eusaprim-dose","tag-eusaprim-side-effects","tag-eusaprim-uses","tag-infusion","tag-medicine","tag-sulfamethoxazole","tag-sulfamethoxazole-dose","tag-sulfamethoxazole-side-effects","tag-sulfamethoxazole-uses"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8506","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=8506"}],"version-history":[{"count":62,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8506\/revisions"}],"predecessor-version":[{"id":42813,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8506\/revisions\/42813"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=8506"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=8506"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=8506"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}