{"id":8430,"date":"2021-03-12T09:25:56","date_gmt":"2021-03-12T09:25:56","guid":{"rendered":"https:\/\/zeepedia.com\/?p=8430"},"modified":"2021-04-13T18:31:24","modified_gmt":"2021-04-13T18:31:24","slug":"esomeprazole-sun-pharma","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/esomeprazole-sun-pharma\/","title":{"rendered":"Esomeprazole SUN Pharma &#8211; Esomeprazole uses, dose and side effects"},"content":{"rendered":"\n<p>\n\n40 mg&nbsp;powder for solution for injection \/ infusion&nbsp;<br>esomeprazole<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Esomeprazole SUN Pharma is and what it is used for<\/h2>\n\n\n\n<p>Esomeprazole SUN Pharma contains a drug called esomeprazole.&nbsp;It belongs to a group of medicines called &#8220;proton pump inhibitors&#8221;.&nbsp;They work by reducing the amount of acid produced in the stomach.<br><\/p>\n\n\n\n<p>Esomeprazole SUN Pharma is used for short-term treatment of certain conditions when you can not be treated with oral ingestion.&nbsp;It is used to treat the following conditions:<br><\/p>\n\n\n\n<p><strong>Adults<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Gastroesophageal reflux&nbsp;disease (&nbsp;GERD&nbsp;).&nbsp;This is when acid from the stomach leaks into the esophagus (the connection between the mouth and the stomach) and causes pain,&nbsp;inflammation,&nbsp;and heartburn.<\/li><li>A gastric ulcer&nbsp;is caused by so-called&nbsp;NSAIDs&nbsp;(Non-steroidal anti-inflammatory drugs).&nbsp;Esomeprazole SUN Pharma can also be used to prevent&nbsp;stomach ulcers&nbsp;when you are taking&nbsp;NSAIDs.<\/li><li>Prevent new bleeding in adults after treatment&nbsp;endoscopy&nbsp;in&nbsp;acute&nbsp;bleeding wounds in the stomach or&nbsp;duodenum.<\/li><\/ul>\n\n\n\n<p><strong>Children and adolescents 1-18 years<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Gastroesophageal reflux&nbsp;disease (&nbsp;GERD&nbsp;).&nbsp;This is when acid from the stomach leaks into the esophagus (the connection between the mouth and the stomach) and causes pain,&nbsp;inflammation,&nbsp;and heartburn.<\/li><\/ul>\n\n\n\n<p>Esomeprazole contained in Esomeprazole SUN Pharma may also be approved for the treatment of other conditions not mentioned in this leaflet.&nbsp;Ask your doctor, pharmacist, or other healthcare professional if you have any further questions, and always follow their instructions.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you use Esomeprazole SUN Pharma<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">You should NOT be given Esomeprazole SUN Pharma if:<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>you are allergic to esomeprazole or any of the other ingredients of this medicine (listed in section 6)<\/li><li>you are allergic to other&nbsp;proton pump inhibitors&nbsp;(eg pantoprazole, lansoprazole, rabeprazole, omeprazole)<\/li><li>you are taking a medicine that contains nelfinavir (used to treat&nbsp;HIV&nbsp;).<\/li><\/ul>\n\n\n\n<p>You should not be given Esomeprazole SUN Pharma if any of the above apply to you.&nbsp;If you are not sure, talk to your doctor before taking this medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor before giving Esomeprazole SUN Pharma about:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>you have severe liver problems<\/li><li>you have severe kidney problems.<\/li><li>you have ever had a skin reaction after treatment with a medicine similar to Esomeprazole SUN Pharma that reduces stomach acid.<\/li><li>you should undergo a specific blood test (chromogranin A).<\/li><\/ul>\n\n\n\n<p><strong>Esomeprazole SUN&nbsp;<\/strong><strong>Pharma&nbsp;<\/strong><strong>may mask symptoms of other diseases.&nbsp;Talk to your doctor immediately if any of the following occur before or after you receive Esomeprazole SUN Pharma:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>you lose a lot of weight for no reason and have trouble swallowing<\/li><li>you get stomach pains or indigestion<\/li><li>you start vomiting food or blood<\/li><li>you get black (blood-mixed) stools.<\/li><\/ul>\n\n\n\n<p>The use of&nbsp;proton pump inhibitors&nbsp;such as Esomeprazole SUN Pharma and especially if you use Esomeprazole SUN for more than one year may increase the risk of hip, wrist, or vertebral fractures.&nbsp;<strong>Tell your doctor<\/strong>&nbsp;if you have osteoporosis (&nbsp;osteoporosis) or if you use medicines called&nbsp;corticosteroids&nbsp;because they may increase the risk of osteoporosis.<br><\/p>\n\n\n\n<p>If you get a rash, especially in areas exposed to the sun, tell your doctor as soon as possible as you may need to stop treatment with Esomeprazole SUN Pharma.&nbsp;Also remember to mention any other&nbsp;side effects, such as joint pain.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Esomeprazole SUN Pharma<\/h2>\n\n\n\n<p>Tell your doctor or nurse if you are taking, have recently taken, or might take any other medicines, including medicines obtained without a prescription.&nbsp;This is because Esomeprazole SUN Pharma may affect the way other medicines work and other medicines may affect the effect of Esomeprazole SUN Pharma.<br><\/p>\n\n\n\n<p>You should not be given Esomeprazole SUN Pharma if you are taking a medicine containing&nbsp;<strong>nelfinavir<\/strong>&nbsp;(used to treat&nbsp;HIV&nbsp;&#8211;&nbsp;infection&nbsp;).<br><\/p>\n\n\n\n<p>Tell your doctor or nurse if you are taking any of the following medicines:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>atazanavir (used in the treatment of&nbsp;HIV&nbsp;&#8211;&nbsp;infection&nbsp;)<\/li><li>clopidogrel (used to prevent blood clots)<\/li><li>ketoconazole&nbsp;, itraconazole or voriconazole (used to treat fungal infections)<\/li><li>Erlotinib (used to treat cancer)<\/li><li>citalopram, imipramine, or clomipramine (used to treat depression)<\/li><li>diazepam&nbsp;(used to treat anxiety, for muscle relaxation, or for&nbsp;epilepsy&nbsp;)<\/li><li>phenytoin&nbsp;(used in&nbsp;epilepsy&nbsp;).&nbsp;If you are taking&nbsp;phenytoin, your doctor will need to monitor when you start or stop taking Esomeprazole SUN Pharma.<\/li><li>drugs used for blood thinning, such as&nbsp;warfarin.&nbsp;Your doctor may need to monitor when you start or stop receiving Esomeprazole SUN Pharma.<\/li><li>Cilostazol (used to treat&nbsp;window disease&nbsp;&#8211; pain in the legs when walking due to insufficient blood supply to the legs)<\/li><li>cisapride (used for digestive problems or heartburn)<\/li><li>Digoxin&nbsp;(used for heart problems)<\/li><li>Methotrexate (a chemotherapeutic drug used in high&nbsp;doses&nbsp;to treat cancer) &#8211; if you are taking high&nbsp;doses&nbsp;of methotrexate, your doctor may pause your treatment with Esomeprazole SUN Pharma<\/li><li>Tacrolimus (used in organ transplantation)<\/li><li>Rifampicin (used to treat&nbsp;tuberculosis&nbsp;)<\/li><li>St. John&#8217;s wort&nbsp;&#8211;&nbsp;<em>Hypericum perforatum<\/em>&nbsp;(used to treat depression).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.&nbsp;Your doctor will decide if you can be given Esomeprazole SUN Pharma during that time.<br><\/p>\n\n\n\n<p>It is not known if Esomeprazole SUN Pharma passes into breast milk.&nbsp;Therefore, you should not be given Esomeprazole SUN Pharma if you are breast-feeding.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Esomeprazole SUN Pharma is unlikely to affect your ability to drive or use tools or machines.&nbsp;However, side effects&nbsp;such as dizziness and visual disturbances may occur in less common cases (see section 4).&nbsp;If you are affected, do not drive or use machines.<br><\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.&nbsp;One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or&nbsp;side effects.&nbsp;Descriptions of these effects and&nbsp;side effects&nbsp;can be found in other sections.&nbsp;Read all the information in this leaflet for guidance.&nbsp;If you are not sure, talk to your doctor or pharmacist.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Esomeprazole SUN Pharma contains sodium<\/h2>\n\n\n\n<p>This medicine contains less than 1 mmol&nbsp;sodium&nbsp;(23 mg) per&nbsp;dose, ie essentially &#8216;sodium-free&#8217;.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. How Esomeprazole SUN Pharma is given<\/h2>\n\n\n\n<p>Esomeprazole SUN Pharma can be given to children and adolescents aged 1 to 18 years and adults, including the elderly.<br><\/p>\n\n\n\n<p><strong>Getting Esomeprazole SUN Pharma<\/strong><\/p>\n\n\n\n<p><strong><em>Adults<\/em><\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Esomeprazole SUN Pharma will be given to you by a doctor who will decide how much you need.<\/li><li>The recommended&nbsp;dose&nbsp;is 20 mg or 40 mg once daily<\/li><li>If you have severe liver problems, the maximum&nbsp;dose is&nbsp;20 mg daily (&nbsp;GERD&nbsp;)<\/li><li>The medicine will be given to you as an&nbsp;injection&nbsp;or&nbsp;infusion&nbsp;(drip) into one of your veins.&nbsp;This will last for up to 30 minutes<\/li><li>The recommended&nbsp;dose&nbsp;to prevent new bleeding in ulcers of the stomach or&nbsp;duodenum&nbsp;is 80 mg given as an&nbsp;intravenous&nbsp;infusion&nbsp;over 30 minutes followed by a&nbsp;continuous&nbsp;infusion&nbsp;of 8 mg per hour given over 3 days.&nbsp;If you have severe liver problems, the&nbsp;dose&nbsp;for continuous&nbsp;infusion&nbsp;may be reduced to 4 mg per hour for 3 days.<\/li><\/ul>\n\n\n\n<p><strong><em>Children aged 1-18 years<\/em><\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>You will receive Esomeprazole SUN Pharma from your doctor, who will decide how much you need.<\/li><li>For children aged 1 to 11 years, the recommended&nbsp;dose is&nbsp;10 or 20 mg once daily,<\/li><li>For children aged 12 to 18 years, the recommended&nbsp;dose is&nbsp;one 20 or 40 mg once daily,<\/li><li>The drug is given as an&nbsp;injection&nbsp;or&nbsp;infusion&nbsp;(drip) into a vein (a blood vessel).&nbsp;It takes up to 30 minutes.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">If you are given too much Esomeprazole SUN<\/h2>\n\n\n\n<p>Contact your doctor immediately if you think you have been given too much Esomeprazole SUN Pharma.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects,&nbsp;although not everybody gets them.<br><\/p>\n\n\n\n<p><strong>Serious&nbsp;side effects&nbsp;are<\/strong><\/p>\n\n\n\n<p><strong>If you notice any of the following serious&nbsp;side effects, contact your doctor immediately:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>sudden wheezing, swelling of the lips, tongue and throat or body, rash, fainting, or difficulty swallowing (severe&nbsp;allergic reaction&nbsp;)<\/li><li>redness&nbsp;of the skin with blistering or flaking.&nbsp;Severe blistering and bleeding on the lips, eyes, mouth, nose, and genitals may also occur.&nbsp;These may be symptoms of &#8220;Stevens-Johnson syndrome&#8221; or &#8220;toxic&nbsp;epidermal&nbsp;necrolysis&#8221;.<\/li><li>yellowed skin, dark urine, and fatigue, which can be symptoms of liver problems.<\/li><\/ul>\n\n\n\n<p>These&nbsp;side effects&nbsp;are rare (may affect up to 1 in 1,000 people) or very rare (may affect up to 1 in 10,000 users).<br><\/p>\n\n\n\n<p><strong>Other&nbsp;side effects&nbsp;are<\/strong><\/p>\n\n\n\n<p><strong>Common (may affect up to 1 in 10 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>headache<\/li><li>effects on the stomach or intestines: diarrhea, abdominal pain, constipation, flatulence<\/li><li>nausea or vomiting<\/li><li>the reaction at the injection site<\/li><li>benign&nbsp;polyps&nbsp;in the stomach.<\/li><\/ul>\n\n\n\n<p><strong>Uncommon (may affect up to 1 in 100 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>swelling in the feet and ankles<\/li><li>sleep disorders (insomnia)<\/li><li>dizziness, tingling, drowsiness<\/li><li>vertigo (&nbsp;vertigo&nbsp;)<\/li><li>vision problems, such as blurred vision<\/li><li>dry mouth<\/li><li>changes in the blood picture that show the function of the liver<\/li><li>skin rash, hives, and&nbsp;itching<\/li><li>Hip, wrist, or vertebral fractures (if Esomeprazole SUN Pharma is used in high&nbsp;doses&nbsp;and for a long time).<\/li><\/ul>\n\n\n\n<p><strong>Rare (may affect up to 1 in 1,000 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>altered blood count such as reduced number of&nbsp;white blood cells&nbsp;or&nbsp;platelets.&nbsp;This may cause weakness, bruising, or susceptibility to infection.<\/li><li>low levels of&nbsp;sodium&nbsp;in the blood.&nbsp;This can cause weakness, vomiting, and cramps.<\/li><li>the feeling of upset, confusion, or depression<\/li><li>taste changes<\/li><li>sudden wheezing or shortness of breath (&nbsp;bronchospasm&nbsp;)<\/li><li>inflammation&nbsp;of the oral cavity<\/li><li>a fungal infection called &#8220;cod&#8221; that can affect the gut<\/li><li>hair loss (&nbsp;alopecia&nbsp;)<\/li><li>skin rash when sunbathing<\/li><li>joint pain (&nbsp;arthralgia&nbsp;) or muscle pain (&nbsp;myalgia&nbsp;)<\/li><li>general malaise and lack of energy<\/li><li>increased sweating.<\/li><\/ul>\n\n\n\n<p><strong>Very rare (may affect up to 1 in 10,000 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>changes in blood count including&nbsp;agranulocytosis&nbsp;(lack of&nbsp;white blood cells&nbsp;)<\/li><li>aggression<\/li><li>hallucinations (see, feel, or hear things that do not exist)<\/li><li>severe liver problems leading to liver failure and encephalitis<\/li><li>muscle weakness<\/li><li>severe kidney problems<\/li><li>Enlargement of the mammary glands in men<\/li><\/ul>\n\n\n\n<p><strong>Has been reported (occurs in an unknown number of users)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Low levels of&nbsp;magnesium&nbsp;in the blood can manifest as fatigue, involuntary muscle movements, confusion, cramps, dizziness, and rapid heartbeat.&nbsp;This is more likely if you have used Esomeprazole SUN Pharma for more than three months.&nbsp;<strong>If you get any of these symptoms, contact your doctor immediately.&nbsp;<\/strong>Low levels of&nbsp;magnesium&nbsp;can also lead to decreased levels of&nbsp;potassium&nbsp;or&nbsp;calcium&nbsp;in the blood.&nbsp;Your doctor may measure the level of magnesium in your blood using regular blood tests.<\/li><li>Inflammation&nbsp;of the intestine (causes diarrhea).<\/li><li>Skin rash, possibly with joint pain.<\/li><\/ul>\n\n\n\n<p>In very rare cases, esomeprazole SUN Pharma can affect the white&nbsp;blood cells&nbsp;so that the immune system is weakened.&nbsp;<strong>You must contact a doctor immediately<\/strong>&nbsp;if you get an&nbsp;infection&nbsp;with symptoms such as fever and severe general malaise, fever with symptoms of local&nbsp;infection&nbsp;such as pain in the neck, throat, or mouth, or difficulty urinating so that any lack of&nbsp;white blood cells&nbsp;(&nbsp;agranulocytosis&nbsp;) can be ruled out through a blood test.&nbsp;It is important that you then information about your medication.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Esomeprazole SUN Pharma<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<br><\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton or vial after EXP.&nbsp;The expiration date is the last day of the specified month.<br><\/p>\n\n\n\n<p>Do not store above 30 \u00b0 C.&nbsp;Store in the original package.&nbsp;Sensitive to light.<\/p>\n\n\n\n<p>After reconstitution: Store in a cool place.<\/p>\n\n\n\n<p>The product should be used immediately.&nbsp;The doctor and pharmacist at the hospital are responsible for storing, using, and disposing of Esomeprazole SUN Pharma.<br><\/p>\n\n\n\n<p>Do not use this medicine if you notice a visual change of the medicine (only a clear solution should be used).<br><\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is esomeprazole sodium.&nbsp;Each bottle contains 42.5 mg of esomeprazole sodium, equivalent to 40 mg of esomeprazole.<\/li><li>The other ingredients are disodium edetate and sodium hydroxide (for&nbsp;adjustment).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>Esomeprazole SUN Pharma is a white or almost white porous and uniform lyophilized powder.&nbsp;It is packaged in a colorless 10 ml&nbsp;glass&nbsp;vial&nbsp;with gray chlorobutyl rubber stopper and aluminum seal and contains 40 mg powder for solution for injection\/infusion.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>pack of 1&nbsp;vial<\/li><li>pack of 10 vials.<\/li><\/ul>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorisation Holder<\/h2>\n\n\n\n<p>Sun Pharmaceutical Industries Europe BV<\/p>\n\n\n\n<p>Polarisavenue 87<\/p>\n\n\n\n<p>2132 JH Hoofddorp<\/p>\n\n\n\n<p>Netherlands<br><\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Laboratories NORMON, SA<\/p>\n\n\n\n<p>Ronda de Valdecarrizo 6<\/p>\n\n\n\n<p>28760 Tres Cantos, Madrid<\/p>\n\n\n\n<p>Spain<br><\/p>\n","protected":false},"excerpt":{"rendered":"<p> 40 mg powder for solution for injection \/ infusion<br \/>\nesomeprazole<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2205,2200],"tags":[3600,3602,3603,3604,3606,3607,3605,3601,2215,2212],"class_list":["post-8430","post","type-post","status-publish","format-standard","hentry","category-e","category-medicines","tag-esomeprazole","tag-esomeprazole-dose","tag-esomeprazole-side-effects","tag-esomeprazole-sun-pharma","tag-esomeprazole-sun-pharma-dose","tag-esomeprazole-sun-pharma-side-effects","tag-esomeprazole-sun-pharma-uses","tag-esomeprazole-uses","tag-injection","tag-medicine"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8430","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=8430"}],"version-history":[{"count":5,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8430\/revisions"}],"predecessor-version":[{"id":10146,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8430\/revisions\/10146"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=8430"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=8430"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=8430"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}