{"id":8428,"date":"2021-03-12T09:24:43","date_gmt":"2021-03-12T09:24:43","guid":{"rendered":"https:\/\/zeepedia.com\/?p=8428"},"modified":"2021-04-13T18:33:06","modified_gmt":"2021-04-13T18:33:06","slug":"esomeprazole-stada-2","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/esomeprazole-stada-2\/","title":{"rendered":"Esomeprazole Stada &#8211; Esomeprazole uses, dose and side effects"},"content":{"rendered":"\n<p>\n\n40 mg&nbsp;powder for solution for injection \/ infusion&nbsp;<br>esomeprazole<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Esomeprazole Stada is and what it is used for<\/h2>\n\n\n\n<p>Esomeprazole Stada contains a drug substance called esomeprazole.&nbsp;It belongs to a group of medicines called &#8220;proton pump inhibitors&#8221;.&nbsp;These work by reducing the amount of acid produced in the stomach.<br><\/p>\n\n\n\n<p>Esomeprazole Stada is used for short-term treatment of certain conditions when you can not be treated with oral ingestion.&nbsp;It is used to treat the following conditions:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Gastroesophageal reflux&nbsp;disease (&nbsp;GERD&nbsp;).&nbsp;This is when acid from the stomach leaks into the esophagus (the connection between the mouth and the stomach) and causes pain,&nbsp;inflammation,&nbsp;and heartburn<\/li><li>A gastric ulcer&nbsp;is caused by so-called&nbsp;NSAIDs&nbsp;(Non-steroidal anti-inflammatory drugs).&nbsp;Esomeprazole Stada may also be used to prevent the formation of&nbsp;ulcers&nbsp;when taking&nbsp;NSAIDs&nbsp;-l\u00e4kemedel<\/li><li>Prevent new bleeding after&nbsp;therapeutic&nbsp;endoscopy&nbsp;in&nbsp;acute&nbsp;bleeding wounds in the stomach or&nbsp;duodenum<\/li><\/ul>\n\n\n\n<p><strong>Children and adolescents 1-18 years<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Gastroesophageal reflux&nbsp;disease (&nbsp;GERD&nbsp;).&nbsp;This is when acid from the stomach leaks into the esophagus (the connection between the mouth and the stomach) and causes pain,&nbsp;inflammation,&nbsp;and heartburn.<\/li><\/ul>\n\n\n\n<p>Esomeprazole contained in Esomeprazole Stada may also be approved for the treatment of other conditions not mentioned in this product information.&nbsp;Ask your doctor, pharmacist, or another healthcare professional if you have any further questions, and always follow their instructions.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before using Esomeprazole Stada<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Esomeprazole Stada<\/h2>\n\n\n\n<p><strong>You should not be given Esomeprazole Stada:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to esomeprazole or any of the other ingredients of this medicine (listed in section 6)<\/li><li>if you are allergic to other&nbsp;proton pump inhibitors&nbsp;(eg pantoprazole, lansoprazole, rabeprazole, omeprazole)<\/li><li>if you are taking a medicine containing nelfinavir (used to treat&nbsp;HIV&nbsp;&#8211;&nbsp;infection&nbsp;).<\/li><\/ul>\n\n\n\n<p>You should not be given Esomeprazole Stada if any of the above apply to you.&nbsp;If you are not sure, talk to your doctor or nurse before taking this medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor or nurse before giving Esomeprazole Stada about:<br><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>you have severe liver problems<\/li><li>you have severe kidney problems<\/li><li>if you have ever had a skin reaction after treatment with medicine like Esomeprazole Stada that reduces stomach acid<\/li><li>if you are going to have a specific blood test (chromogranin A).<\/li><\/ul>\n\n\n\n<p>Esomeprazole Stada may mask symptoms of other diseases.<br><\/p>\n\n\n\n<p><strong>Therefore, if any of the following occur before or after you are given Esomeprazole Stada, contact your doctor immediately:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>You lose a lot of weight for no reason and have trouble swallowing.<\/li><li>You get stomach pains or indigestion.<\/li><li>You start vomiting food or blood.<\/li><li>You get black (blood-mixed) stools.<\/li><\/ul>\n\n\n\n<p>Using&nbsp;proton pump inhibitors&nbsp;such as Esomeprazole Stada and especially if you use Esomeprazole Stada for more than one year may increase the risk of hip, wrist, or vertebral fractures.&nbsp;Tell your doctor if you have osteoporosis (&nbsp;osteoporosis&nbsp;) or if you use medicines called&nbsp;corticosteroids&nbsp;because they may increase the risk of osteoporosis.<br><\/p>\n\n\n\n<p>If you get a rash, especially in areas exposed to the sun, tell your doctor as soon as possible as you may need to stop taking Esomeprazole Stada.&nbsp;Also remember to mention any other&nbsp;side effects, such as joint pain.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Esomeprazole Stada<\/h2>\n\n\n\n<p>Tell your doctor or nurse if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n<p>This is because Esomeprazole Stada can affect the way other medicines work and other medicines can affect the effect of Esomeprazole Stada.<br><\/p>\n\n\n\n<p>You should not be given Esomeprazole STADA if you are taking a medicine containing nelfinavir (used to treat&nbsp;HIV&nbsp;&#8211;&nbsp;infection&nbsp;).<br><\/p>\n\n\n\n<p>Tell your doctor or nurse if you are taking any of the following medicines:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Atazanavir (used for the treatment of&nbsp;HIV&nbsp;&#8211;&nbsp;infection&nbsp;).<\/li><li>Clopidogrel (used to prevent blood clots).<\/li><li>Ketoconazole&nbsp;, itraconazole or voriconazole (used to treat fungal infections).<\/li><li>Erlotinib (used to treat cancer).<\/li><li>Citalopram, imipramine, or clomipramine (used to treat depression).<\/li><li>Diazepam&nbsp;(used to treat anxiety, muscle relaxation, or epilepsy&nbsp;).<\/li><li>Phenytoin&nbsp;(used in&nbsp;epilepsy&nbsp;).&nbsp;If you are taking&nbsp;phenytoin, your doctor will need to monitor when you start or stop taking Esomeprazole Stada.<\/li><li>Drugs used for blood thinning, such as&nbsp;warfarin.&nbsp;Your doctor may need to monitor when you start or stop taking Esomeprazole Stada.<\/li><li>Cilostazol (used to treat&nbsp;window disease&nbsp;&#8211;<\/li><li>Cisapride (used for indigestion or heartburn).<\/li><li>Digoxin&nbsp;(used for heart problems).<\/li><li>Methotrexate (a&nbsp;high-dose&nbsp;chemotherapy&nbsp;drug used to treat cancer) &#8211; If you are taking high&nbsp;doses&nbsp;of methotrexate, your doctor may temporarily stop your treatment with Esomeprazole Stada.<\/li><li>Tacrolimus (organ transplantation).<\/li><li>Rifampicin (used to treat&nbsp;tuberculosis&nbsp;).<\/li><li>St. John&#8217;s wort&nbsp;&#8211;&nbsp;<em>Hypericum perforatum<\/em>&nbsp;(used to treat mild depression and mild anxiety).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n<p>If you are pregnant, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<br><\/p>\n\n\n\n<p>Your doctor will decide if you can be given Esomeprazole Stada during that time.<br><\/p>\n\n\n\n<p>It is not known if esomeprazole passes into breast milk.&nbsp;Therefore, you should not be given Esomeprazole Stada if you are breast-feeding.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Esomeprazole Stada is unlikely to affect your ability to drive or use tools or machines.&nbsp;However, side effects&nbsp;such as dizziness and visual disturbances may occur in less common cases.&nbsp;(see section 4).&nbsp;If you are affected, do not drive or use machines.<br><\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.&nbsp;One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or&nbsp;side effects.&nbsp;Descriptions of these effects and&nbsp;side effects&nbsp;can be found in other sections.&nbsp;Read all the information in this leaflet for guidance.&nbsp;If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Esomeprazole Stada contains sodium<\/h2>\n\n\n\n<p>This medicine contains less than 1 mmol (23 mg)&nbsp;sodium&nbsp;per&nbsp;vial&nbsp;before&nbsp;reconstitution, ie.&nbsp;Is next to &#8220;sodium-free&#8221;.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Esomeprazole Stada<\/h2>\n\n\n\n<p><em>Adults<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Esomeprazole Stada will be given to you by a doctor who will decide how much you need.<\/li><li>The recommended&nbsp;dose&nbsp;is 20 mg or 40 mg once daily.<\/li><li>If you have severe liver problems, the maximum&nbsp;dose is&nbsp;20 mg daily (&nbsp;GERD&nbsp;).<\/li><li>The medicine will be given to you as an&nbsp;injection&nbsp;or&nbsp;infusion&nbsp;into one of your veins.&nbsp;This will last for up to 30 minutes.<\/li><li>The recommended&nbsp;dose&nbsp;to prevent new bleeding in ulcers of the stomach or&nbsp;duodenum&nbsp;is 80 mg given as an&nbsp;intravenous&nbsp;infusion&nbsp;over 30 minutes followed by a&nbsp;continuous&nbsp;infusion&nbsp;of 8 mg per hour for 3 days.<\/li><li>If you have severe liver problems, the&nbsp;dose&nbsp;for continuous&nbsp;infusion&nbsp;may be reduced to 4 mg per hour for 3 days.<\/li><\/ul>\n\n\n\n<p><\/p>\n\n\n\n<p><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Use for children and adolescents<\/h2>\n\n\n\n<p><em>Children aged 1 to 18 years<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>You will be given Esomeprazole Stada by your doctor, who will decide how much you need.<\/li><li>For children aged 1 to 11 years, the recommended&nbsp;dose is&nbsp;10 or 20 mg once daily.<\/li><li>For children aged 12 to 18 years, the recommended&nbsp;dose is&nbsp;20 or 40 mg once daily.<\/li><li>The medicine is given to you as an&nbsp;injection&nbsp;or&nbsp;infusion&nbsp;into a vein (a blood vessel).&nbsp;It takes up to 30 minutes.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">If you use more Esomeprazole Stada than you should &nbsp;<\/h2>\n\n\n\n<p>Contact your doctor immediately if you think you have been given too much Esomeprazole Stada.<br><\/p>\n\n\n\n<p>If you have ingested too much medicine or if e.g.&nbsp;a child has ingested the medicine by mistake, contact a doctor, hospital, or the Poison Information Center for risk assessment and advice.&nbsp;Do this even if you \/ the child does not notice any symptoms.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects, although not everybody gets them.<br><\/p>\n\n\n\n<p><strong>Stop taking Esomeprazole Stada and contact your doctor immediately if you notice any of the following serious side effects:<\/strong><br><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Sudden wheezing, swelling of the lips, tongue, and throat or body, rash, fainting, or difficulty swallowing (severe&nbsp;allergic reaction&nbsp;).<\/li><li>Redness&nbsp;of the skin with blistering or flaking.&nbsp;Severe blistering and bleeding on the lips, eyes, mouth, nose, and genitals may also occur.&nbsp;This can be &#8220;Stevens-Johnson syndrome&#8221; or &#8220;toxic&nbsp;epidermal&nbsp;necrolysis&#8221;.<\/li><li>Yellowed skin, dark urine, and fatigue can be symptoms of liver problems.<\/li><\/ul>\n\n\n\n<p>These&nbsp;side effects&nbsp;are rare and may affect up to 1 in 1,000 people.<br><\/p>\n\n\n\n<p>Other&nbsp;side effects&nbsp;include:<br><\/p>\n\n\n\n<p><strong>Common<\/strong>&nbsp;(may affect up to 1 in 10 people)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Headache.<\/li><li>Effects on the stomach or intestines: diarrhea, abdominal pain, constipation, flatulence.<\/li><li>Nausea or vomiting.<\/li><li>The reaction at the injection site.<\/li><li>Benign&nbsp;polyps&nbsp;are in the stomach.<\/li><\/ul>\n\n\n\n<p><strong>Uncommon<\/strong>(may affect up to 1 in 100 people)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Swelling of the feet and ankles.<\/li><li>Sleep disorders (insomnia).<\/li><li>Dizziness, tingling, drowsiness.<\/li><li>Scams (&nbsp;vertigo&nbsp;).<\/li><li>Vision problems, such as blurred vision.<\/li><li>Dry mouth.<\/li><li>Changes in the blood picture show the function of the liver.<\/li><li>Skin rash, hives, and&nbsp;itching.<\/li><li>Hip, wrist, or vertebral fractures (if Esomeprazole Stada is used in high&nbsp;doses&nbsp;and for a long time).<\/li><\/ul>\n\n\n\n<p><strong>Rare<\/strong>(may affect up to 1 in 1,000 people)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Altered blood count such as reduced number of&nbsp;white blood cells&nbsp;or&nbsp;platelets.&nbsp;This may cause weakness, bruising, or susceptibility to infection.<\/li><li>Low levels of&nbsp;sodium&nbsp;in the blood.&nbsp;This can cause weakness, vomiting, and cramps.<\/li><li>Feeling of agitation, confusion, or depression.<\/li><li>Taste changes.<\/li><li>Sudden wheezing or shortness of breath (&nbsp;bronchospasm&nbsp;).<\/li><li>Inflammation&nbsp;of the oral cavity.<\/li><li>A fungal infection called &#8220;cod&#8221; can affect the intestines.<\/li><li>Liver problems including jaundice, which can cause yellowing of the skin, dark urine, and fatigue.<\/li><li>Hair loss (&nbsp;alopecia&nbsp;).<\/li><li>Skin rash when sunbathing.<\/li><li>Joint pain (&nbsp;arthralgia&nbsp;) or muscle pain (&nbsp;myalgia&nbsp;).<\/li><li>General malaise and lack of energy.<\/li><li>Increased sweating.<\/li><\/ul>\n\n\n\n<p><\/p>\n\n\n\n<p><strong>Very rare<\/strong>(may affect up to 1 in 10,000 people)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Changes in the blood picture including&nbsp;agranulocytosis&nbsp;(lack of&nbsp;white blood cells&nbsp;).<\/li><li>Aggression.<\/li><li>See, feel or hear things that do not exist (hallucinations).<\/li><li>Severe liver problems leading to liver failure and encephalitis.<\/li><li>Sudden onset of severe rash, blistering or flaky skin.&nbsp;This may be associated with high fever and joint pain (Erythema multiforme,&nbsp;Stevens-Johnson&nbsp;syndrome,&nbsp;toxic epidermal necrolysis&nbsp;).<\/li><li>Muscle weakness.<\/li><li>Severe kidney problems.<\/li><li>Enlargement of the mammary glands in men.<\/li><\/ul>\n\n\n\n<p>Esomeprazole Stada can in very rare cases affect the white&nbsp;blood cells&nbsp;so that the immune system is weakened.&nbsp;If you get an&nbsp;infection&nbsp;with symptoms such as fever and severe general malaise or fever with symptoms of local&nbsp;infection&nbsp;such as pain in the neck, throat, or mouth or difficulty urinating, you must contact a doctor as soon as possible so that any lack of&nbsp;white blood cells&nbsp;(&nbsp;agranulocytosis&nbsp;) can be excluded by a blood test.&nbsp;It is important that you then information about your medication.<br><\/p>\n\n\n\n<p><strong>Has been reported<\/strong>&nbsp;(occurs in an unknown number of users):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>If you use Esomeprazole Stada for more than three months, your blood magnesium levels may drop.&nbsp;Low levels of&nbsp;magnesium&nbsp;can manifest as fatigue, involuntary muscle movements, confusion, cramps, dizziness, and rapid heartbeat.&nbsp;If you get any of these symptoms, contact your doctor immediately.&nbsp;Low levels of&nbsp;magnesium&nbsp;can also lead to decreased levels of&nbsp;potassium&nbsp;or&nbsp;calcium&nbsp;in the blood.&nbsp;Your doctor may measure the level of magnesium in your blood using regular blood tests.<\/li><li>Inflammation&nbsp;of the intestine (causes diarrhea).<\/li><li>If you have very low levels of&nbsp;magnesium, you may also have low levels of&nbsp;calcium&nbsp;in your blood.<\/li><li>Skin rash, possibly with joint pain.<\/li><\/ul>\n\n\n\n<p>Do not worry about this list of possible&nbsp;side effects.&nbsp;You may not be affected by any of them.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Esomeprazole Stada<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<br><\/p>\n\n\n\n<p>The doctor and pharmacy staff at the hospital are responsible for the correct storage, use, and disposal of Esomeprazole Stada.<br><\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton or vial after EXP.&nbsp;The expiration date is the last day of the specified month.<br><\/p>\n\n\n\n<p>Do not store above 30 \u00b0 C.<br><\/p>\n\n\n\n<p>Keep the vial in the outer carton.&nbsp;Sensitive to light.&nbsp;However, the vials can be stored outside the carton exposed to normal indoor light for up to 24 hours.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is esomeprazole sodium.&nbsp;Each&nbsp;vial&nbsp;of powder for solution for injection or infusion contains 42.5 mg of esomeprazole sodium, equivalent to 40 mg of esomeprazole.<\/li><li>The other ingredients are disodium edetate and sodium hydroxide (for&nbsp;adjustment).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>Esomeprazole Stada is a white to off-white powder cake or powder.&nbsp;This is made into a solution before it is given to you.<\/p>\n\n\n\n<p>10 ml&nbsp;vial&nbsp;of colorless borosilicate glass, type I. Stopper of bromobutyl rubber latex.&nbsp;aluminum cap and plastic flip-off seal.<\/p>\n\n\n\n<p>Pack sizes: 1&nbsp;vial&nbsp;, 1 x 10 vials.<br><\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p>STADA Arzneimittel AG<\/p>\n\n\n\n<p>Stadastrasse 2-18<\/p>\n\n\n\n<p>61118 Bad Vilbel<\/p>\n\n\n\n<p>Germany<br><\/p>\n\n\n\n<p><strong>Local representative<\/strong><\/p>\n\n\n\n<p>STADA Nordic ApS<\/p>\n\n\n\n<p>Marielundvej 46 A<\/p>\n\n\n\n<p>2730 Herlev<\/p>\n\n\n\n<p>Denmark<br><\/p>\n","protected":false},"excerpt":{"rendered":"<p>40 mg powder for solution for injection \/ infusion<br \/>\nesomeprazole<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2205,2200],"tags":[3600,3602,3603,3608,3610,3611,3609,3601,2215,2212],"class_list":["post-8428","post","type-post","status-publish","format-standard","hentry","category-e","category-medicines","tag-esomeprazole","tag-esomeprazole-dose","tag-esomeprazole-side-effects","tag-esomeprazole-stada","tag-esomeprazole-stada-dose","tag-esomeprazole-stada-side-effects","tag-esomeprazole-stada-uses","tag-esomeprazole-uses","tag-injection","tag-medicine"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8428","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=8428"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8428\/revisions"}],"predecessor-version":[{"id":10148,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8428\/revisions\/10148"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=8428"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=8428"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=8428"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}