{"id":8391,"date":"2021-03-11T10:56:37","date_gmt":"2021-03-11T10:56:37","guid":{"rendered":"https:\/\/zeepedia.com\/?p=8391"},"modified":"2021-04-14T17:55:52","modified_gmt":"2021-04-14T17:55:52","slug":"esomeprazole-actavis","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/esomeprazole-actavis\/","title":{"rendered":"Esomeprazole Actavis &#8211; Esomeprazole uses, dose and side effects"},"content":{"rendered":"\n<p>\n\n20 mg and 40 mg&nbsp;enteric tablets&nbsp;are&nbsp;<br>esomeprazole<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Esomeprazole Actavis is and what it is used for<\/h2>\n\n\n\n<p>Esomeprazole Actavis contains a medicine called esomeprazole.&nbsp;It belongs to a group of medicines called &#8220;proton pump inhibitors&#8221;.&nbsp;These work by reducing the amount of acid produced in the stomach.<br><\/p>\n\n\n\n<p>Esomeprazole Actavis is used to treat the following conditions:<br><\/p>\n\n\n\n<p><strong>Adults<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Gastroesophageal reflux disease&nbsp;(&nbsp;GERD&nbsp;).&nbsp;This is when acid from the stomach leaks into the esophagus (the connection between the mouth and the stomach) and causes pain,&nbsp;inflammation,&nbsp;and heartburn.<\/li><li>Ulcers in the stomach or upper intestine are infected by a&nbsp;bacterium&nbsp;called&nbsp;<em>&#8220;Helicobacter pylori&#8221;<\/em>.&nbsp;If you have such wounds, your doctor may also prescribe&nbsp;antibiotics&nbsp;to treat the&nbsp;infection&nbsp;and to allow wound healing.<\/li><li>A gastric ulcer&nbsp;is caused by so-called&nbsp;NSAIDs&nbsp;(non-steroidal anti-inflammatory drugs).&nbsp;Esomeprazole Actavis can also be used to prevent&nbsp;stomach ulcers&nbsp;when you are taking&nbsp;NSAIDs.<\/li><li>Too much acid in the stomach is caused by a&nbsp;tumor&nbsp;in the pancreas (Zollinger-Ellison syndrome).<\/li><li>Continued treatment to prevent new bleeding from wounds after treatment with&nbsp;intravenous&nbsp;esomeprazole.<\/li><\/ul>\n\n\n\n<p><strong>Young people from 12 years<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Gastroesophageal reflux disease&nbsp;(&nbsp;GERD&nbsp;).&nbsp;This is when acid from the stomach leaks into the esophagus (the connection between the mouth and stomach) and causes pain,&nbsp;inflammation,&nbsp;and heartburn.<\/li><li>Ulcers in the stomach or upper intestine are infected by a&nbsp;bacterium&nbsp;called&nbsp;<em>Helicobacter pylori<\/em>.&nbsp;If you have such wounds, your doctor may also prescribe&nbsp;antibiotics&nbsp;to treat the&nbsp;infection&nbsp;and to allow wound healing.<\/li><\/ul>\n\n\n\n<p>Esomeprazole contained in Esomeprazole Actavis may also be authorized for the treatment of other conditions not mentioned in this leaflet.&nbsp;Ask your doctor, pharmacist, or other healthcare professional if you have any further questions, and always follow their instructions.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you use Esomeprazole Actavis<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Esomeprazole Actavis<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic (hypersensitive) to esomeprazole or any of the other ingredients of this medicine (listed in section 6).<\/li><li>if you are allergic to other&nbsp;proton pump inhibitors&nbsp;(eg pantoprazole, lansoprazole, rabeprazole, omeprazole).<\/li><li>if you are taking a medicine containing nelfinavir (used to treat&nbsp;HIV&nbsp;&#8211;&nbsp;infection&nbsp;).<\/li><\/ul>\n\n\n\n<p>Do not take Esomeprazole Actavis if any of the above apply to you.&nbsp;If you are not sure, talk to your doctor or pharmacist before taking Esomeprazole Actavis.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before taking Esomeprazole Actavis:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have severe liver problems.<\/li><li>if you have severe kidney problems.<\/li><li>if you have ever had a skin reaction after treatment with a medicine similar to Esomeprazole Actavis that reduces stomach acid.<\/li><li>if you are going to have a specific blood test (chromogranin A)<\/li><\/ul>\n\n\n\n<p>Esomeprazole Actavis may mask the symptoms of other diseases.&nbsp;<strong>Therefore, if any of the following occur before you start taking Esomeprazole Actavis or while you are taking it, contact your doctor immediately:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>you lose a lot of weight for no reason and have trouble swallowing<\/li><li>you get stomach pains or indigestion<\/li><li>you start vomiting food or blood<\/li><li>you get black (blood-mixed) stools.<\/li><\/ul>\n\n\n\n<p>If you have been prescribed Esomeprazole Actavis to take \u201cas needed\u201d, consult your doctor if your symptoms persist or change in nature.<br><\/p>\n\n\n\n<p>Talk to your doctor if you have severe or persistent diarrhea;&nbsp;esomeprazole has been associated with a small increased risk of&nbsp;infectious&nbsp;diarrhea.<br><\/p>\n\n\n\n<p>Using&nbsp;proton pump inhibitors&nbsp;such as Esomeprazole Actavis, and especially if you use it for more than a year, may increase the risk of a hip, wrist, or vertebral fracture (bone fracture).&nbsp;Tell your doctor if you have osteoporosis (&nbsp;osteoporosis&nbsp;) or if you use medicines called&nbsp;corticosteroids&nbsp;because they may increase the risk of osteoporosis.<br><\/p>\n\n\n\n<p>If you get a rash, especially in areas exposed to the sun, tell your doctor as soon as possible as you may need to stop treatment with Esomeprazole Actavis.&nbsp;Also remember to mention any other&nbsp;side effects, such as joint pain.<br><\/p>\n\n\n\n<p><em>Children under 12 years<\/em><\/p>\n\n\n\n<p>Esomeprazole Actavis should not be used in children under 12 years of age.&nbsp;More suitable formulations of this drug may be available.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Esomeprazole Actavis<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.&nbsp;This is because Esomeprazole Actavis can affect the way other medicines work and other medicines can affect the effect of Esomeprazole Actavis.<br><\/p>\n\n\n\n<p>Do not take Esomeprazole Actavis if you are taking a medicine containing&nbsp;<strong>nelfinavir<\/strong>(used to treat&nbsp;HIV&nbsp;&#8211;&nbsp;infection&nbsp;).<br><\/p>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking any of the following medicines:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>atazanavir (used in the treatment of&nbsp;HIV&nbsp;&#8211;&nbsp;infection&nbsp;).<\/li><li>clopidogrel (used to prevent blood clots)<\/li><li>ketoconazole&nbsp;, itraconazole or voriconazole (used to treat fungal infections)<\/li><li>erlotinib (used to treat cancer)<\/li><li>citalopram, imipramine, or clomipramine (used to treat depression)<\/li><li>diazepam&nbsp;(used to treat anxiety, for muscle relaxation, or epilepsy&nbsp;)<\/li><li>phenytoin&nbsp;(used in&nbsp;epilepsy&nbsp;).&nbsp;If you are taking&nbsp;phenytoin, your doctor will need to monitor you when you start or stop taking Esomeprazole Actavis.<\/li><li>drugs used for blood thinning, such as&nbsp;warfarin.&nbsp;Your doctor may need to monitor you when you start or stop taking Esomeprazole Actavis.<\/li><li>cilostazol (used to treat&nbsp;window disease&nbsp;&#8211; pain in the legs when walking due to insufficient blood supply to the legs)<\/li><li>cisapride (used for digestive problems or heartburn)<\/li><li>digoxin&nbsp;(used for heart problems)<\/li><li>methotrexate (a chemotherapy drug used in the high&nbsp;dose&nbsp;you to treat cancer) &#8211; if you take high&nbsp;dose&nbsp;s of methotrexate, your doctor may do a temporary suspension of treatment with Esomeprazole Actavis&nbsp;gastro&nbsp;s<\/li><li>tacrolimus (organ transplant)<\/li><li>rifampicin (used to treat&nbsp;tuberculosis&nbsp;)<\/li><li>St. John&#8217;s wort&nbsp;(Hypericum perforatum) (used to treat depression).<\/li><\/ul>\n\n\n\n<p>If the doctor has prescribed the&nbsp;antibiotics&nbsp;amoxicillin and clarithromycin, coupled with Esomeprazole Actavis&nbsp;gastro&nbsp;you to treat&nbsp;ulcers&nbsp;caused by&nbsp;<em>Helicobacter pylori<\/em>&nbsp;&#8211;&nbsp;infection, you must tell your doctor if you are also taking other medicines.<br><\/p>\n\n\n\n<p><strong>Esomeprazole Actavis with food and drink<\/strong><\/p>\n\n\n\n<p>You can take your tablets with a meal or on an &#8220;empty stomach&#8221;.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n<p>If you are pregnant, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n<p>Your doctor will decide if you can take Esomeprazole Actavis during that time.<\/p>\n\n\n\n<p>It is not known if esomeprazole passes into breast milk.&nbsp;Therefore, you should not take Esomeprazole Actavis if you are breast-feeding.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Esomeprazole Actavis is unlikely to affect your ability to drive or use tools or machines.&nbsp;However, side effects&nbsp;such as dizziness and visual disturbances may occur in less common cases.&nbsp;(see section 4).&nbsp;If you are affected, do not drive or use machines.<br><\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.&nbsp;One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or&nbsp;side effects.&nbsp;Descriptions of these effects and&nbsp;side effects&nbsp;can be found in other sections.&nbsp;Read all the information in this leaflet for guidance.&nbsp;If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Esomeprazole Actavis contains sodium and sucrose<\/h2>\n\n\n\n<p><strong>Esomeprazole Actavis contains&nbsp;sodium<\/strong><\/p>\n\n\n\n<p>This medicine contains less than 1 mmol (23 mg)&nbsp;sodium&nbsp;per&nbsp;enteric-tablet, ie&nbsp;essentially &#8216;sodium-free&nbsp;&#8216;.<br><\/p>\n\n\n\n<p><strong>Esomeprazole Actavis&nbsp;<\/strong><strong>contains sucrose<\/strong><\/p>\n\n\n\n<p>This medicine contains sugar spheres, which contain sucrose, which is a type of sugar.&nbsp;If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Esomeprazole Actavis<\/h2>\n\n\n\n<p>Always take this medicine exactly as your doctor or pharmacist has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>If you use this medicine for a long time, your doctor will want to follow up on your treatment (especially if you are taking the medicine for more than a year).<\/li><li>If you have been told by your doctor that you must take this medicine, tell your doctor if your symptoms change.<\/li><\/ul>\n\n\n\n<p><strong>How much should you take?<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Your doctor will tell you how many tablets to take and how long to take them.&nbsp;Dosage&nbsp;one depends on your condition, how old you are, and how well your liver is working.<\/li><li>The recommended&nbsp;dose&nbsp;is listed below.<\/li><\/ul>\n\n\n\n<p><em><strong>Use for&nbsp;<\/strong><strong>adults over 18 years<\/strong><\/em><\/p>\n\n\n\n<p><strong>For the treatment of heartburn caused by&nbsp;gastroesophageal reflux disease&nbsp;(&nbsp;GERD&nbsp;):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>If your doctor has found that your esophagus is slightly damaged, the recommended&nbsp;dose is&nbsp;one Esomeprazole Actavis 40 mg&nbsp;enteric tablet&nbsp;once daily for 4 weeks.&nbsp;Your doctor may recommend that you take the same&nbsp;dose&nbsp;for another 4 weeks if the damage to your esophagus is not healed.<\/li><li>The recommended&nbsp;dose&nbsp;after the esophagus has healed is an Esomeprazole Actavis 20 mg&nbsp;enteric tablet&nbsp;once daily.<\/li><li>If your esophagus is not damaged, the recommended&nbsp;dose is&nbsp;one Esomeprazole Actavis 20 mg&nbsp;enteric tablet&nbsp;once daily.&nbsp;When your condition is under control, your doctor may recommend that you take the medicine up to a maximum of one Esomeprazole Actavis 20 mg&nbsp;enteric tablet&nbsp;once a day&nbsp;if necessary.<\/li><li>If you have a severe hepatic impairment, your doctor may recommend a lower&nbsp;dose.<\/li><\/ul>\n\n\n\n<p><strong>To treat ulcers caused by&nbsp;<em>Helicobacter pylori<\/em>&nbsp;&#8211;&nbsp;infection&nbsp;and to prevent the ulcer from occurring again:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>The recommended&nbsp;dose&nbsp;is an Esomeprazole Actavis 20 mg&nbsp;enteric tablet&nbsp;twice daily for one week.<\/li><li>Your doctor will also recommend that you take&nbsp;antibiotics&nbsp;such as amoxicillin and clarithromycin.<\/li><\/ul>\n\n\n\n<p><strong>For the treatment of&nbsp;stomach ulcers&nbsp;caused by&nbsp;NSAIDs&nbsp;(non-steroidal anti-inflammatory drugs):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>The recommended&nbsp;dose&nbsp;is an Esomeprazole Actavis 20 mg&nbsp;enteric tablet&nbsp;once daily for 4-8 weeks.<\/li><\/ul>\n\n\n\n<p><strong>To prevent&nbsp;stomach ulcers&nbsp;if you are taking NSAIDs:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>The recommended&nbsp;dose&nbsp;is an Esomeprazole Actavis 20 mg&nbsp;enteric tablet&nbsp;once daily.<\/li><\/ul>\n\n\n\n<p><strong>For the treatment of excess acid in the stomach caused by a&nbsp;tumor&nbsp;of the pancreas (Zollinger-Ellison syndrome):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>The recommended&nbsp;dose&nbsp;is an Esomeprazole Actavis 40 mg&nbsp;enteric-tablet&nbsp;twice daily.<\/li><li>Your doctor will adjust the&nbsp;dose&nbsp;according to your needs and will also decide how long you should take the medicine.&nbsp;The maximum&nbsp;dose&nbsp;is 80 mg twice daily.<\/li><\/ul>\n\n\n\n<p><strong>Continued treatment to prevent new bleeding from wounds after treatment with&nbsp;intravenous&nbsp;esomeprazole:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>The recommended&nbsp;dose&nbsp;is an Esomeprazole Actavis 40 mg&nbsp;enteric tablet&nbsp;once daily for 4 weeks.<br><\/li><\/ul>\n\n\n\n<p><strong><em>Use for young people from 12 years<\/em><\/strong><\/p>\n\n\n\n<p><strong>For the treatment of heartburn caused by&nbsp;gastroesophageal reflux&nbsp;disease (&nbsp;GERD&nbsp;):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>If your doctor has found that your esophagus is slightly damaged, the recommended&nbsp;dose is&nbsp;one Esomeprazole Actavis 40 mg&nbsp;enteric tablet&nbsp;once daily for 4 weeks.&nbsp;Your doctor may recommend that you take the same&nbsp;dose&nbsp;for another 4 weeks if the damage to your esophagus is not healed<\/li><li>The recommended&nbsp;dose&nbsp;one after the esophagus is healed is an Esomeprazole Actavis 20 mg&nbsp;enteric tablet&nbsp;once daily<\/li><li>If your esophagus is not damaged, the recommended&nbsp;dose is&nbsp;one Esomeprazole Actavis 20 mg&nbsp;enteric tablet&nbsp;once daily.<\/li><li>If you have a severe hepatic impairment, your doctor may recommend a lower&nbsp;dose<\/li><\/ul>\n\n\n\n<p><strong>To treat ulcers caused by&nbsp;<em>Helicobacter pylori<\/em>&nbsp;&#8211;&nbsp;infection&nbsp;and to prevent the ulcer&nbsp;<\/strong><strong>from occurring again:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>The recommended&nbsp;dose&nbsp;is an Esomeprazole Actavis 20 mg&nbsp;enteric tablet&nbsp;twice daily for one week.<\/li><li>Your doctor will also recommend that you take&nbsp;antibiotics&nbsp;such as amoxicillin and clarithromycin<\/li><\/ul>\n\n\n\n<p><strong>Taking the medicine<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>You can take the tablets at any time of the day.<\/li><li>You can take your tablets with a meal or on an &#8220;empty stomach&#8221;.<\/li><li>Swallow your tablets whole along with a glass of water.&nbsp;Do not chew or crush the tablets.&nbsp;This is because the tablets contain coated granules that prevent the medicine from being broken down by the acid in the stomach.&nbsp;The granules mustn&#8217;t be damaged.<\/li><\/ul>\n\n\n\n<p><strong>What you can do if you have difficulty swallowing the tablets<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>If you have problems swallowing the tablets:<ul><li>Put them in glass (not carbonated) water.&nbsp;Do not use other liquids.<\/li><li>Stir until the tablets fall apart (&nbsp;mixture&nbsp;becomes cloudy).&nbsp;Drink the&nbsp;mixture immediately or within 30 minutes.&nbsp;Always&nbsp;stir the mixture&nbsp;immediately before drinking it.<\/li><li>To be sure that you have ingested all the medicine, rinse thoroughly with another half glass of water that you drink up.&nbsp;The solid particles contain the medicine &#8211; do not chew or crush them.<\/li><\/ul><\/li><li>If you can not swallow at all, the tablets can be mixed with a little water and placed in a&nbsp;syringe.&nbsp;Mixture&nbsp;one can then be given directly into the stomach via a probe.<\/li><\/ul>\n\n\n\n<p><strong>Use for children under 12 years<\/strong><\/p>\n\n\n\n<p>Esomeprazole Actavis should not be used in children under 12 years of age.&nbsp;More suitable formulations of this drug may be available.<br><\/p>\n\n\n\n<p><strong>Older<\/strong><\/p>\n\n\n\n<p>Dose adjustment is not necessary for elderly patients.<br><\/p>\n\n\n\n<p><strong>If you take more Esomeprazole Actavis then you should<\/strong><\/p>\n\n\n\n<p>If you have ingested too much medicine or if e.g.&nbsp;If a child has inadvertently ingested the medicine, contact a doctor, hospital, or the Poison Information Center for risk assessment and advice.<br><\/p>\n\n\n\n<p><strong>If you forget to take Esomeprazole Actavis&nbsp;gastro&nbsp;s<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>If you forget to take a&nbsp;dose&nbsp;, take it as soon as you notice it.&nbsp;If it is near the time of the next&nbsp;dose&nbsp;&#8211; skip the missed&nbsp;dose&nbsp;.<\/li><li>Do not take a double&nbsp;dose&nbsp;(two&nbsp;doses&nbsp;at the same time) to compensate for a missed&nbsp;dose&nbsp;.<\/li><\/ul>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects,&nbsp;although not everybody gets them.<br><\/p>\n\n\n\n<p><strong>Stop taking Esomeprazole Actavis and contact your doctor immediately, if you notice any of the following serious side effects:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Sudden wheezing, swelling of the lips, tongue and throat or body, skin rash, fainting or difficulty swallowing (severe&nbsp;allergic reaction&nbsp;, rare).<\/li><li>Redness&nbsp;of the skin with blistering or flaking.&nbsp;Severe blistering and bleeding on the lips, eyes, mouth, nose and genitals may also occur.&nbsp;This can be &#8220;erythema multiforme&#8221;, &#8220;Stevens-Johnson syndrome&#8221; or &#8220;toxic&nbsp;epidermal&nbsp;necrolysis&#8221;, very rare.<\/li><li>Yellowed skin, dark urine and fatigue, which can be symptoms of liver problems, rare.<\/li><\/ul>\n\n\n\n<p>Other&nbsp;side effects&nbsp;include:<br><\/p>\n\n\n\n<p><strong>Common (affects up to 1 in 10 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>headache.<\/li><li>effects on the stomach or intestines: diarrhea, abdominal pain, constipation, flatulence.<\/li><li>nausea or vomiting.<\/li><li>benign&nbsp;polyps&nbsp;in the stomach.<br><\/li><\/ul>\n\n\n\n<p><strong>Uncommon (affects up to 1 in 100 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>swelling in the feet and ankles<\/li><li>sleep disorders (insomnia).<\/li><li>dizziness, tingling, drowsiness<\/li><li>vertigo (&nbsp;vertigo&nbsp;)<\/li><li>dry mouth<\/li><li>changes in the blood picture that show the function of the liver<\/li><li>skin rash, hives and&nbsp;itching&nbsp;.<\/li><li>hip, wrist or vertebral fractures (if Esomeprazole Actavis&nbsp;enteric-tablet&nbsp;is used in high&nbsp;doses&nbsp;and for a long time).<br><\/li><\/ul>\n\n\n\n<p><strong>Rare (affects up to 1 in 1,000 people):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>altered blood count such as reduced number of&nbsp;white blood cells&nbsp;or&nbsp;platelets&nbsp;.&nbsp;This may cause weakness, bruising or susceptibility to infection<\/li><li>low levels of&nbsp;sodium&nbsp;in the blood.&nbsp;This can cause weakness, vomiting and cramps<\/li><li>feeling of upset, confusion or depression<\/li><li>taste changes<\/li><li>vision problems, such as blurred vision<\/li><li>sudden wheezing or shortness of breath (&nbsp;bronchospasm&nbsp;)<\/li><li>inflammation&nbsp;of the oral cavity<\/li><li>a fungal infection called &#8220;cod&#8221; that can affect the gut<\/li><li>liver problems including jaundice, which can cause yellowing of the skin, dark urine and fatigue<\/li><li>hair loss (&nbsp;alopecia&nbsp;)<\/li><li>skin rash when sunbathing<\/li><li>joint pain (&nbsp;arthralgia&nbsp;) or muscle pain (&nbsp;myalgia&nbsp;)<\/li><li>general malaise and lack of energy<\/li><li>increased sweating.<br><\/li><\/ul>\n\n\n\n<p><strong>Very rare (may affect up to 1 in 10,000 people)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>changes in blood count including&nbsp;agranulocytosis&nbsp;(lack of&nbsp;white blood cells&nbsp;)<\/li><li>aggression<\/li><li>hallucinations (see, feel or hear things that do not exist)<\/li><li>severe liver problems leading to liver failure and encephalitis<\/li><li>sudden onset of severe rash, blistering or flaky skin.&nbsp;This may be associated with high fever and joint pain (Erythema multiforme,&nbsp;Stevens-Johnson&nbsp;syndrome,&nbsp;toxic epidermal necrolysis&nbsp;)<\/li><li>muscle weakness<\/li><li>severe kidney problems<\/li><li>enlargement of the mammary glands in men.<br><\/li><\/ul>\n\n\n\n<p><strong>No known frequency (cannot be calculated from the available data)<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>If you use Esomeprazole Actavis for more than three months, your blood magnesium levels may drop.&nbsp;Low levels of&nbsp;magnesium&nbsp;can manifest as fatigue, involuntary muscle movements, confusion, cramps, dizziness and rapid heartbeat.&nbsp;If you get any of these symptoms, contact your doctor immediately.&nbsp;Low levels of&nbsp;magnesium&nbsp;can also lead to decreased levels of&nbsp;potassium&nbsp;or&nbsp;calcium&nbsp;in the blood.&nbsp;Your doctor may measure the level of magnesium in your blood using regular blood tests.<\/li><li>Inflammation&nbsp;of the intestine (causes diarrhea).<\/li><li>Skin rash, possibly with joint pain.<br><\/li><\/ul>\n\n\n\n<p>Esomeprazole Actavis can in very rare cases affect the white&nbsp;blood cells&nbsp;so that the immune system is weakened.&nbsp;If you get an&nbsp;infection&nbsp;with symptoms such as fever and&nbsp;<strong>severe<\/strong>&nbsp;general malaise or fever with symptoms of local&nbsp;infection&nbsp;such as pain in the neck, throat or mouth or difficulty urinating, you must contact a doctor as soon as possible so that any lack of&nbsp;white blood cells&nbsp;(&nbsp;agranulocytosis&nbsp;) can excluded by a blood test.&nbsp;It is important that you then inform about your medication.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Esomeprazole Actavis<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Keep out of sight and reach of children.<\/li><li>Do not store above 30 \u00b0 C.<\/li><li>Esomeprazole Actavis delivered in plastic cans must be used within 6 months of first opening.<\/li><li>Do not use this medicine after the expiry date which is stated on the carton, jar or blister after EXP.&nbsp;The expiration date is the last day of the specified month.<\/li><li>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is esomeprazole magnesium dihydrate.An Esomeprazole Actavis 20 mg&nbsp;enteric-&nbsp;containing&nbsp;tablet&nbsp;contains 20 mg of esomeprazole (equivalent to 21.75 mg of esomeprazole magnesium dihydrate salt).An Esomeprazole Actavis 40 mg&nbsp;enteric-&nbsp;containing&nbsp;tablet&nbsp;contains 40 mg of esomeprazole (equivalent to 43.5 mg of esomeprazole magnesium dihydrate salt).<\/li><\/ul>\n\n\n\n<ul class=\"wp-block-list\"><li>Other ingredients are:<em>Tablet:<\/em>Methacrylic acid-ethyl acrylate copolymer (1: 1), talc, triethyl citrate, hypromellose, sugar spheres, magnesium stearate, hydroxypropylcellulose, glycerol monostearate 40-55, polysorbate 80, microcrystalline cellulose, povidone, macrogol 6000, crospovidarum, sodium.<em>Drag:<\/em>Hypromellose, titanium dioxide (E171), macrogol \/ PEG 400, red iron oxide (E172), yellow iron oxide (E172).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and contents of the pack<\/h2>\n\n\n\n<p>Esomeprazole Actavis 20 mg&nbsp;enteric tablets&nbsp;are light pink, oblong, biconvex film-coated tablets, 6.55 x 13.6 mm.<\/p>\n\n\n\n<p>Esomeprazole Actavis 40 mg&nbsp;enteric tablets&nbsp;are pink, oblong, biconvex film-coated tablets, 8.2 x 17 mm.<br><\/p>\n\n\n\n<p><em>Pack sizes<\/em>&nbsp;:<\/p>\n\n\n\n<p>Plastic jar with tablets, desiccant and plastic lid: 30, 100, 250 or 500 tablets.&nbsp;Do not swallow the desiccant.<\/p>\n\n\n\n<p>Blister packs: 7, 14, 28, 30, 50, 56, 60, 90, 98, 100 or 140 tablets.&nbsp;(Packages 7, 14 and 28 are over-the-counter)<br><\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p><strong>Marketing Authorisation Holder<\/strong><\/p>\n\n\n\n<p>Actavis Group PTC ehf.<\/p>\n\n\n\n<p>Reykjavikurvegur 76-78<\/p>\n\n\n\n<p>220 Hafnarfjordur<\/p>\n\n\n\n<p>Iceland<br><\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Balkanpharma Dupnitsa AD<\/p>\n\n\n\n<p>3 Samokovsko Shose Str.<\/p>\n\n\n\n<p>Dupnitsa 2600<\/p>\n\n\n\n<p>Bulgaria<br><\/p>\n","protected":false},"excerpt":{"rendered":"<p> 20 mg and 40 mg enteric tablets are<br \/>\nesomeprazole<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2205,2200],"tags":[3600,3636,3638,3639,3637,3602,3603,3601,2212,2211],"class_list":["post-8391","post","type-post","status-publish","format-standard","hentry","category-e","category-medicines","tag-esomeprazole","tag-esomeprazole-actavis","tag-esomeprazole-actavis-dose","tag-esomeprazole-actavis-side-effects","tag-esomeprazole-actavis-uses","tag-esomeprazole-dose","tag-esomeprazole-side-effects","tag-esomeprazole-uses","tag-medicine","tag-tablets"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8391","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=8391"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8391\/revisions"}],"predecessor-version":[{"id":10185,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8391\/revisions\/10185"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=8391"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=8391"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=8391"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}