{"id":8316,"date":"2021-03-10T07:56:29","date_gmt":"2021-03-10T07:56:29","guid":{"rendered":"https:\/\/zeepedia.com\/?p=8316"},"modified":"2021-04-26T13:07:06","modified_gmt":"2021-04-26T13:07:06","slug":"ertapenem-fresenius-kabi","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/ertapenem-fresenius-kabi\/","title":{"rendered":"Ertapenem Fresenius Kabi &#8211; Ertapenem uses, dose and side effects"},"content":{"rendered":"\n<p> 1 g of\u00a0powder to concentrate for\u00a0infusion\u00a0solution\u00a0<br>ertapenem<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What Ertapenem Fresenius Kabi is and what it is used for<\/h2>\n\n\n\n<p>Ertapenem Fresenius Kabi contains ertapenem, an&nbsp;antibiotic&nbsp;belonging to the&nbsp;beta-lactam&nbsp;group.&nbsp;It has the ability to kill a large number of different bacteria (&nbsp;microorganisms&nbsp;) that cause&nbsp;infection&nbsp;in different parts of the body.<br><\/p>\n\n\n\n<p>Ertapenem Fresenius Kabi can be given to individuals who are three months and older.<br><\/p>\n\n\n\n<p>Treatment:<\/p>\n\n\n\n<p>Your doctor has prescribed Ertapenem Fresenius Kabi for you or your child to have one (or more) of the following types of infections:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Infection&nbsp;of the abdomen<\/li><li>Infection&nbsp;affecting the lungs (&nbsp;pneumonia&nbsp;)<\/li><li>Gynecological&nbsp;infection&nbsp;er<\/li><li>Skin infections of the foot in diabetics<\/li><\/ul>\n\n\n\n<p>Prophylaxis:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Prophylaxis&nbsp;against&nbsp;infection&nbsp;in adults in the area where the surgery was performed after surgery in the colon or rectum.<\/li><\/ul>\n\n\n\n<p>Ertapenem contained in Ertapenem Fresenius Kabi may also be approved for the treatment of other conditions not mentioned in this product information.&nbsp;Ask your doctor, pharmacist, or another healthcare professional if you have any further questions, and always follow their instructions.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2. What you need to know before you get Ertapenem Fresenius Kabi<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Ertapenem Fresenius Kabi<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to the active substance (ertapenem) or any of the other ingredients of this medicine (listed in section 6).<\/li><li>if you are allergic to&nbsp;antibiotics&nbsp;such as&nbsp;penicillins,&nbsp;cephalosporins,&nbsp;or carbapenems (used to treat various&nbsp;infections&nbsp;).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor, pharmacist, or nurse before using Ertapenem Fresenius Kabi:<\/p>\n\n\n\n<p>If you get an&nbsp;allergic reaction&nbsp;during treatment&nbsp;(such as swelling of the face, tongue, or throat, difficulty breathing or swallowing, rash), you should contact your doctor as soon as possible as you may need medical treatment immediately.<br><\/p>\n\n\n\n<p>Although&nbsp;antibiotics&nbsp;including Ertapenem Fresenius Kabi kill some bacteria, other bacteria and fungi can continue to grow more than normal.&nbsp;This is called overgrowth.&nbsp;Your doctor will monitor you for overgrowth and, if necessary, give you treatment.<br><\/p>\n\n\n\n<p>You must tell your doctor if you have diarrhea before, during, or after your treatment with Ertapenem Fresenius Kabi.&nbsp;This is because you may have a condition called&nbsp;colitis&nbsp;(inflammation&nbsp;of the colon).&nbsp;Do not take any medicine to treat diarrhea without first discussing it with your doctor.<br><\/p>\n\n\n\n<p>Tell your doctor if you are taking the medicines&nbsp;valproic acid&nbsp;or sodium valproate (see&nbsp;<strong>Other medicines and&nbsp;Ertapenem Fresenius Kabi <\/strong>below).<br><\/p>\n\n\n\n<p>Tell your doctor about the diseases you have or have had:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Kidney disease.&nbsp;Your doctor must know if you have kidney disease and if you are undergoing dialysis treatment.<\/li><li>Drug allergies, including antibiotics.<\/li><li>Diseases of the&nbsp;central nervous system, such as limited tremors or seizures.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Children and adolescents (3 months to 17 years of age)<\/h2>\n\n\n\n<p>Experience with Ertapenem Fresenius Kabi in children younger than two years is limited.&nbsp;For this age group, the doctor assesses the possible benefits of the treatment.&nbsp;There is no experience in children under 3 months of age.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Ertapenem Fresenius Kabi<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines, including medicines obtained without a prescription.<br><\/p>\n\n\n\n<p>Tell your doctor, nurse, or pharmacist if you are taking medicines containing&nbsp;valproic acid&nbsp;or sodium valproate (used to treat&nbsp;epilepsy,&nbsp;bipolar disorder,&nbsp;migraine,&nbsp;and schizophrenia).&nbsp;This is because Ertapenem Fresenius Kabi can affect the way other medicines work.&nbsp;Your doctor will decide if you should use Ertapenem Fresenius Kabi at the same time as any of these medicines.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>You must tell your doctor if you are pregnant or planning to become pregnant before receiving Ertapenem Fresenius Kabi.<\/p>\n\n\n\n<p>Ertapenem Fresenius Kabi has not been studied in pregnant women.&nbsp;Ertapenem Fresenius Kabi should not be used during pregnancy unless your doctor considers that the potential benefit outweighs the potential risk to the fetus.<br><\/p>\n\n\n\n<p>Before you are treated with Ertapenem Fresenius Kabi, you must tell your doctor if you are breast-feeding or planning to start breast-feeding.<\/p>\n\n\n\n<p>Because Ertapenem Fresenius Kabi has been found in breast milk, women receiving Ertapenem Fresenius Kabi should not breast-feed as the breast-fed baby may be affected.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Do not drive or use machines until you know how you react to the medicine.&nbsp;Certain&nbsp;side effects, such as dizziness and drowsiness, have been reported with Ertapenem Fresenius Kabi, which may affect some patients&#8217; ability to drive or use machines.<br><\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.&nbsp;One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or&nbsp;side effects.&nbsp;Descriptions of these effects and&nbsp;side effects&nbsp;can be found in other sections.&nbsp;Read all the information in this leaflet for guidance.&nbsp;If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Ertapenem Fresenius Kabi contains sodium<\/h2>\n\n\n\n<p>This medicine contains 137 mg&nbsp;sodium&nbsp;(the main ingredient in table salt\/table salt) per&nbsp;vial.&nbsp;This corresponds to 6.9% of the maximum recommended daily&nbsp;sodium intake&nbsp;for adults.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Ertapenem Fresenius Kabi<\/h2>\n\n\n\n<p>Ertapenem Fresenius Kabi will always be mixed and given&nbsp;intravenously&nbsp;(into a vein) by a doctor or other healthcare professional.<br><\/p>\n\n\n\n<p>The recommended&nbsp;dose&nbsp;of Ertapenem Fresenius Kabi for adults and adolescents 13 years of age or older is 1 gram (g) once daily.&nbsp;The recommended&nbsp;dose&nbsp;for children between 3 months and 12 years of age is 15 mg\/kg given twice daily (1 g \/ day must not be exceeded).&nbsp;Your doctor will decide how many days you need to receive treatment.<br><\/p>\n\n\n\n<p>In the&nbsp;prophylaxis&nbsp;of&nbsp;infection&nbsp;in the area where the surgery was performed after surgery in the colon or rectum, the usual&nbsp;dose is&nbsp;1 g and is given&nbsp;intravenously&nbsp;as a single dose one hour before the operation.<br><\/p>\n\n\n\n<p>You must continue to receive Ertapenem Fresenius Kabi for as long as your doctor prescribes it.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you take more Ertapenem Fresenius Kabi then you should<\/h2>\n\n\n\n<p>If you have ingested too much medicine or if e.g.&nbsp;If a child has inadvertently ingested the medicine, contact a doctor, hospital, or the Poison Information Center for risk assessment and advice.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you have missed a dose of Ertapenem Fresenius Kabi&nbsp;<\/h2>\n\n\n\n<p>If you are concerned that you may have missed a&nbsp;dose, contact your doctor or another healthcare professional immediately.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects, although not everybody gets them.<br><\/p>\n\n\n\n<p><strong><em>Adults 18 years or older<\/em><\/strong><\/p>\n\n\n\n<p>Since the drug was introduced to the market, severe allergic reactions (&nbsp;anaphylaxis&nbsp;) and hypersensitivity syndromes (allergic reactions with rash, fever, and abnormal blood tests) have been reported.&nbsp;The first signs of a severe&nbsp;allergic reaction&nbsp;may be swelling of the face and\/or throat.&nbsp;If these signs of illness occur, contact your doctor as soon as possible as you may need medical treatment immediately.<br><\/p>\n\n\n\n<p>Common (may affect up to 1 in 10 people)&nbsp;side effects&nbsp;are:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Headache<\/li><li>Diarrhea, nausea, vomiting<\/li><li>Rash,&nbsp;itching<\/li><li>Problems with the vein in which the medicine is given (including&nbsp;inflammation, the formation of a lump, swelling at the injection site, or leakage of fluid into the&nbsp;tissue and skin around the injection site)<\/li><li>Increased&nbsp;platelet count<\/li><li>Altered liver function values.<\/li><\/ul>\n\n\n\n<p>Uncommon (may affect up to 1 in 100 people)&nbsp;side effects&nbsp;are:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Dizziness, drowsiness, difficulty sleeping, confusion, seizures<\/li><li>Low&nbsp;blood pressure, slow heart rate<\/li><li>Shortness of breath, sore throat<\/li><li>Constipation, yeast infection in the mouth, diarrhea associated with antibiotic treatment, acid reflux,&nbsp;dry mouth, impaired digestion, loss of appetite<\/li><li>Reddening of the skin<\/li><li>Discharges and irritation in the abdomen<\/li><li>Stomach pain, fatigue, fungal infection, fever, edema\/swelling, chest pain, altered taste sensation<\/li><li>Alteration of certain blood and urine samples.<\/li><\/ul>\n\n\n\n<p>Rare (may affect up to 1 in 1,000 people)&nbsp;side effects&nbsp;are:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Decreased&nbsp;white blood cell count, decreased&nbsp;platelet count<\/li><li>Low blood sugar<\/li><li>Upset, anxiety, depression, tremors<\/li><li>Irregular heartbeat, high&nbsp;blood pressure, bleeding, fast heartbeat<\/li><li>Nasal congestion, cough, nosebleeds,&nbsp;pneumonia, altered breathing sounds, wheezing<\/li><li>Inflammation&nbsp;of the gallbladder, difficulty swallowing, fecal incontinence, jaundice, liver disease<\/li><li>Skin inflammation, fungal infection of the skin, skin flaking,&nbsp;infection&nbsp;of the wound after surgery<\/li><li>Muscle cramps, shoulder pain<\/li><li>Urinary tract infection, kidney problems<\/li><li>Miscarriage, abdominal bleeding<\/li><li>Allergy malaise,&nbsp;inflammation&nbsp;of the pelvic floor, changes in the white part of the eye, fainting.<\/li><\/ul>\n\n\n\n<p>No known frequency (cannot be calculated from the available data):&nbsp;<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Hallucinations<\/li><li>Decreased level of consciousness<\/li><li>Changed mood (including aggression,&nbsp;delirium, disorientation, changes in mood)<\/li><li>Abnormal movements<\/li><li>Muscle weakness<\/li><li>Unsteady gait<\/li><li>Discoloration of teeth.<\/li><\/ul>\n\n\n\n<p>There have also been reports of changes in certain laboratory values.<br><\/p>\n\n\n\n<p>If you experience raised or fluid-filled skin spots all over your body, talk to your doctor or nurse immediately.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children and adolescents (3 months to 17 years old)<\/h2>\n\n\n\n<p>Common (may affect up to 1 in 10 people)&nbsp;side effects&nbsp;are:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Diarrhea<\/li><li>Diaper rash<\/li><li>Pain at the infusion site<\/li><li>Change in the number of&nbsp;white blood cells<\/li><li>Altered liver function values.<\/li><\/ul>\n\n\n\n<p>Uncommon (may affect up to 1 in 100 people)&nbsp;side effects&nbsp;are:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Headache<\/li><li>Hot flashes, high&nbsp;blood pressure, red or reddish-purple flat dots as big as pinheads under the skin<\/li><li>Discolored stools, black tar-like stools<\/li><li>Reddening of the skin, itchy skin<\/li><li>Burning sensation,&nbsp;itching,&nbsp;redness,&nbsp;and heat at the infusion&nbsp;site,&nbsp;redness&nbsp;at the injection site<\/li><li>Increased&nbsp;platelet count<\/li><li>Alteration of certain blood samples.<\/li><\/ul>\n\n\n\n<p>No known frequency (frequency can not be calculated from the available data):&nbsp;<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Hallucinations<\/li><li>Changed mood (including aggression).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Ertapenem Fresenius Kabi<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<br><\/p>\n\n\n\n<p>Use before the expiry date which is stated on the vial.&nbsp;The expiration date is the last day of the specified month.<br><\/p>\n\n\n\n<p>Do not store above 25 \u00b0 C.<br><\/p>\n\n\n\n<p>After reconstitution: Reconstituted solutions should be used immediately.<br><\/p>\n\n\n\n<p>After dilution: Dilute solutions (approximately 20 mg\/ml ertapenem) are physically and chemically stable for 6 hours at 25 \u00b0 C or 24 hours at 2 \u00b0 C &#8211; 8 \u00b0 C (in a refrigerator).&nbsp;The solution should be used within 4 hours after removal from the refrigerator.&nbsp;Ertapenem Fresenius Kabi solution must not be frozen.<br><\/p>\n\n\n\n<p>From a&nbsp;microbiological&nbsp;point of view, the product should be used immediately.&nbsp;If the product is not used immediately, the user is responsible for the storage time and storage conditions and these should not normally exceed 24 hours at 2-8 \u00b0 C unless preparation\/dilution (etc) has taken place under controlled and validated conditions.<br><\/p>\n\n\n\n<p>Do not use this medicine if you notice particles and discoloration in the reconstituted solution.<br><\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is ertapenem 1 g.<\/li><li>The other ingredients are Sodium bicarbonate (E500) and sodium hydroxide (E524).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>Ertapenem Fresenius Kabi is a white to yellowish lyophilized powder for concentrate for&nbsp;solution&nbsp;for&nbsp;infusion.<\/p>\n\n\n\n<p>The color of solutions of Ertapenem Fresenius Kabi ranges from colorless to pale yellow.&nbsp;Variations within this color scale do not affect the strength of the drug.<\/p>\n\n\n\n<p>Ertapenem Fresenius Kabi is supplied in packs of 10 vials.<br><\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<p><\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>ACS Dobfar SpA<\/p>\n\n\n\n<p>Nucleo Industriale S.Atto<\/p>\n\n\n\n<p>64100 Teramo<\/p>\n\n\n\n<p>Italy<br><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Ertapenem Fresenius Kabi contains ertapenem, an antibiotic belonging to the beta-lactam group. It has the ability to kill a large number of different bacteria ( microorganisms ) that cause infection in different parts of the body.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2205,2200],"tags":[3894,3895,3893,2213,2328,3892,3896],"class_list":["post-8316","post","type-post","status-publish","format-standard","hentry","category-e","category-medicines","tag-ertapenem-fresenius-kabi","tag-ertapenem-fresenius-kabi-side-effects","tag-ertapenem-side-effects","tag-medicines","tag-powder","tag-what-is-ertapenem","tag-what-is-ertapenem-fresenius-kabi"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8316","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=8316"}],"version-history":[{"count":5,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8316\/revisions"}],"predecessor-version":[{"id":10414,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8316\/revisions\/10414"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=8316"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=8316"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=8316"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}