{"id":8312,"date":"2021-03-10T07:51:08","date_gmt":"2021-03-10T07:51:08","guid":{"rendered":"https:\/\/zeepedia.com\/?p=8312"},"modified":"2021-04-26T13:16:43","modified_gmt":"2021-04-26T13:16:43","slug":"erlotinib-stada","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/erlotinib-stada\/","title":{"rendered":"Erlotinib STADA &#8211; Erlotinib uses, dose and side effects"},"content":{"rendered":"\n<p> 25 mg &amp; 100 mg &amp; 150 mg\u00a0film-coated tablets\u00a0<br>erlotinib<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Erlotinib STADA is and what it is used for<\/h2>\n\n\n\n<p>Erlotinib Stada contains the active substance erlotinib.&nbsp;Erlotinib Stada is a medicine used to treat cancer by preventing the activity of a&nbsp;protein&nbsp;called&nbsp;epidermal&nbsp;growth&nbsp;factor&nbsp;receptor (EGFR).&nbsp;This&nbsp;protein&nbsp;is known to be involved in the growth and spread of cancer cells.<br><\/p>\n\n\n\n<p>Erlotinib Stada is used in adults.&nbsp;This medicine can be prescribed for you if you have non-small cell lung cancer&nbsp;at an advanced stage.&nbsp;It can be prescribed as&nbsp;an initial treatment or as treatment if your disease is largely unchanged after&nbsp;initial chemotherapy, provided that your cancer cells have specific EGFR&nbsp;mutations.&nbsp;It can also be prescribed if previous chemotherapy has not been able to stop your disease.<br><\/p>\n\n\n\n<p>This medicine can also be prescribed to you in combination with another treatment called gemcitabine if you have pancreatic cancer with the spread.<br><\/p>\n\n\n\n<p>Erlotinib contained in Erlotinib Stada may also be approved for the treatment of other conditions not mentioned in this product information.&nbsp;Ask your doctor, pharmacist, or other healthcare professional if you have any further questions, and always follow their instructions.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you use Erlotinib STADA<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not take Erlotinib Stada<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to erlotinib or any of the other ingredients of this medicine (listed in section 6).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are taking other medicines that may increase or decrease the amount of erlotinib in your blood or affect the effect of erlotinib (eg&nbsp;antifungals&nbsp;such as&nbsp;ketoconazole,&nbsp;protease inhibitors, erythromycin, clarithromycin,&nbsp;phenytoin, carbamazepine,&nbsp;barbiturates, rifampicin,&nbsp;ciprofloxacin, ranitidine,&nbsp;St. John&#8217;s wort proteasome inhibitor), talk to your doctor.&nbsp;In some cases, these medicines may reduce the effectiveness or increase the&nbsp;side effects&nbsp;of Erlotinib Stada and your doctor may need to adjust your treatment.&nbsp;Your doctor may avoid treating you with these medicines during your Erlotinib Stada treatment<\/li><li>If you are taking&nbsp;anticoagulants&nbsp;(medicines that help prevent blood clots or clotting of the blood, such as&nbsp;warfarin&nbsp;), Erlotinib Stada may increase your tendency to bleed.&nbsp;Talk to your doctor, he will regularly need to examine you with some blood tests<\/li><li>if you are taking statins (medicines that lower cholesterol in the blood), Erlotinib Stada may increase the risk of statin-related muscle problems, which in rare cases can lead to severe muscle breakdown (&nbsp;rhabdomyolysis&nbsp;) leading to kidney damage, talk to your doctor<\/li><li>If you wear contact lenses and\/or if you have previously had eye problems such as severe dry eyes,&nbsp;inflammation,&nbsp;or sores in the front of the eye (&nbsp;cornea&nbsp;), tell your doctor.<\/li><\/ul>\n\n\n\n<p>See also below &#8220;Other medicines and Erlotinib Stada&#8221;<br><\/p>\n\n\n\n<p>You should inform your doctor:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you suddenly have difficulty breathing associated with coughing or fever as your doctor may need to treat you with other medicines and discontinue your Erlotinib Stada treatment;<\/li><li>if you have diarrhea because your doctor may need to treat you with medicines for diarrhea (eg loperamide);<\/li><li>immediately if you have severe or persistent diarrhea, nausea, loss of appetite, or vomiting as your doctor may need to stop your Erlotinib Stada treatment and you may need hospitalization;<\/li><li>if you have severe abdominal pain, severe blisters, or flaking of the skin.&nbsp;Your doctor may need to discontinue or discontinue your treatment;<\/li><li>If you develop&nbsp;acute&nbsp;or worsening&nbsp;redness&nbsp;and pain in the eye, increased tear flow, blurred vision, and\/or photosensitivity, contact your doctor or nurse immediately as you may need&nbsp;urgent&nbsp;care (see Possible&nbsp;side effects&nbsp;below);<\/li><li>if you also take a statin and notice unexplained muscle pain, soreness, weakness,s or cramps.&nbsp;Your doctor may need to stop or stop your treatment.<\/li><\/ul>\n\n\n\n<p>See also section 4 \u201cPossible side effects\u201d.<br><\/p>\n\n\n\n<p><strong>Liver or kidney disease<\/strong><\/p>\n\n\n\n<p>It is not known if Erlotinib Stada has a different effect if your liver or kidneys do not function normally.&nbsp;Treatment with this medicine is not recommended if you have severe liver disease or severe kidney disease.<br><\/p>\n\n\n\n<p><strong>Disruption of glucuronidation such as Gilbert&#8217;s disease<\/strong><\/p>\n\n\n\n<p>Tell your doctor if you have Gilbert&#8217;s disease or any other glucuronidation disorder.<br><\/p>\n\n\n\n<p><strong>Smoking<\/strong><\/p>\n\n\n\n<p>You should stop smoking when you are being treated with Erlotinib Stada as smoking may reduce the amount of your medicine in your blood.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>Erlotinib Stada has not been studied in patients under 18 years of age.&nbsp;Treatment with this drug is not recommended for children and adolescents.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Erlotinib STADA<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Erlotinib Stada with food and drink<\/h2>\n\n\n\n<p>Do not take Erlotinib Stada with food.&nbsp;See also section 3 \u201cHow to take Erlotinib Stada\u201d.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n<p>Avoid getting pregnant during your treatment with Erlotinib Stada.&nbsp;If you can get pregnant, use reliable contraception during treatment, and for at least 2 weeks after taking the last tablet.<\/p>\n\n\n\n<p>If you become pregnant during your treatment with Erlotinib Stada, tell your doctor immediately who will decide whether to continue treatment.<\/p>\n\n\n\n<p>Do not breast-feed if you are being treated with Erlotinib Stada.<br><\/p>\n\n\n\n<p>If you are pregnant or breast-feeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Erlotinib Stada has not been studied for its possible effects on the ability to drive or use machines, but it is very unlikely that your treatment will affect this ability.<br><\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.&nbsp;One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or&nbsp;side effects.&nbsp;Descriptions of these effects and&nbsp;side effects&nbsp;can be found in other sections.&nbsp;Read all the information in this leaflet for guidance.&nbsp;If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Erlotinib STADA contains lactose and sodium<\/h2>\n\n\n\n<p><strong>Erlotinib Stada contains&nbsp;lactose<\/strong><\/p>\n\n\n\n<p>If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.<br><\/p>\n\n\n\n<p><strong>Erlotinib Stada contains&nbsp;sodium<\/strong><\/p>\n\n\n\n<p>This medicine contains less than 1 mmol (23 mg)&nbsp;sodium&nbsp;per tablet, ie&nbsp;essentially &#8216;sodium-free&#8217;.&nbsp;is next to &#8220;sodium-free&#8221;.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to use Erlotinib STADA<\/h2>\n\n\n\n<p>Always take this medicine exactly as your doctor has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<br><\/p>\n\n\n\n<p>The tablet should be taken at least one hour before or two hours after food.<br><\/p>\n\n\n\n<p>The recommended&nbsp;dose&nbsp;is one tablet of Erlotinib Stada 150 mg daily if you have non-small cell lung cancer.<br><\/p>\n\n\n\n<p>The recommended&nbsp;dose&nbsp;is one tablet of Erlotinib Stada 100 mg every day if you have spread pancreatic cancer.&nbsp;Erlotinib Stada is given with gemcitabine treatment.<br><\/p>\n\n\n\n<p>Your doctor may need to adjust your&nbsp;dose&nbsp;step by step with 50 mg at a time.<\/p>\n\n\n\n<p>For the different&nbsp;dosages, Erlotinib Stada is available in strengths of 25 mg, 100 mg, and 150 mg.<br><\/p>\n\n\n\n<p>To be swallowed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you take more Erlotinib Stada then you should<\/h2>\n\n\n\n<p>Contact your doctor or pharmacist immediately.<\/p>\n\n\n\n<p>You may experience increased&nbsp;side effects&nbsp;and your doctor may stop your treatment.<br><\/p>\n\n\n\n<p><strong>If you have ingested too much medicine or if e.g.&nbsp;If a child has accidentally ingested the medicine, contact a doctor, hospital, or the Poison Information Center immediately for assessment of the risk and advice.<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Erlotinib Stada<\/h2>\n\n\n\n<p>If you forget to take one or more&nbsp;doses&nbsp;of Erlotinib Stada, contact your doctor or pharmacist as soon as possible.&nbsp;Do not take a double&nbsp;dose&nbsp;to make up for a forgotten&nbsp;dose.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop taking Erlotinib Stada<\/h2>\n\n\n\n<p>It is important to continue taking Erlotinib Stada every day for as long as your doctor prescribes it for you.<br><\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects, although not everybody gets them.<br><\/p>\n\n\n\n<p>Contact your doctor as soon as possible if you get any of the following&nbsp;side effects.&nbsp;In some cases, your doctor may need to reduce your&nbsp;dose&nbsp;of Erlotinib Stada or discontinue treatment:<br><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Diarrhea or vomiting (may affect more than 1 user in 10).&nbsp;Persistent and severe diarrhea can cause low levels of&nbsp;potassium&nbsp;in the blood and impair your kidney function, especially if you are receiving other chemotherapy at the same time.&nbsp;If you experience severe or persistent diarrhea,&nbsp;contact your doctor immediately as you may need hospitalization.<\/li><\/ul>\n\n\n\n<ul class=\"wp-block-list\"><li>Eye irritation due to corneal and\/or conjunctivitis (very common: may occur in more than 1 in 10 users) and&nbsp;keratitis&nbsp;(&nbsp;corneal inflammation&nbsp;) (common: may occur in up to 1 in 10 users).<\/li><\/ul>\n\n\n\n<ul class=\"wp-block-list\"><li>A form of a lung disease called interstitial lung disease (uncommon in European patients; common in Japanese patients: may affect up to 1 in 100 users in Europe and may affect up to 1 in 10 users in Japan).&nbsp;This disease can also be associated with the natural course of your medical condition and can in some cases be fatal.&nbsp;If you get symptoms such as sudden difficulty breathing associated with cough and fever, contact your doctor immediately, as you may be suffering from this disease.&nbsp;Your doctor may decide to stop your treatment with Erlotinib Stada.<\/li><\/ul>\n\n\n\n<ul class=\"wp-block-list\"><li>Perforation&nbsp;in the gastrointestinal tract has been observed (less common: may affect up to 1 in 100 people).&nbsp;Tell your doctor if you have severe abdominal pain.&nbsp;Also tell your doctor if you have had a&nbsp;stomach ulcer&nbsp;or diverticular disease before, as it may increase this risk.<\/li><\/ul>\n\n\n\n<ul class=\"wp-block-list\"><li>In rare cases, liver failure has been observed (rare: may affect up to 1 in 1,000 people).&nbsp;If your blood tests indicate severe changes in your liver function, your doctor may need to stop your treatment.<\/li><\/ul>\n\n\n\n<p><strong>Very common (may affect more than 1 user in 10):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>the rash may appear or worsen on sun-exposed surfaces.&nbsp;If you are exposed to the sun, protective clothing and\/or the use of sunscreen (eg minerals) may be appropriate.<\/li><li>infection<\/li><li>loss of appetite, weight loss<\/li><li>Depression<\/li><li>headache, altered sensitivity of the skin, or numbness in the arms and legs<\/li><li>difficulty breathing, cough<\/li><li>nausea<\/li><li>irritation in the mouth<\/li><li>stomach pain, stomach upset, flatulence<\/li><li>abnormal liver function values<\/li><li>itching, dry skin, and hair loss<\/li><li>fatigue, fever, stiffness.<\/li><\/ul>\n\n\n\n<p><strong>Common (may affect up to 1 in 10 people):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>nosebleeds<\/li><li>bleeding from the stomach or intestines<\/li><li>inflammatory reactions around fingernails<\/li><li>inflammation&nbsp;of the hair follicles<\/li><li>acne<\/li><li>skin cracks (skin fissures)<\/li><li>renal impairment (when Erlotinib Stada is given outside the approved indication in combination with&nbsp;chemotherapy&nbsp;).<\/li><\/ul>\n\n\n\n<p><strong>Uncommon (may affect up to 1 in 100 people):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>changes&nbsp;eyelash&nbsp;s<\/li><li>increased hair with the male pattern on body and face<\/li><li>changes of eyebrows<\/li><li>brittle and loose nails.<\/li><\/ul>\n\n\n\n<p><strong>Rare (may affect up to 1 in 1,000 people):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>flushed or painful palms or soles of the feet (hand-foot syndrome).<\/li><\/ul>\n\n\n\n<p><strong>Very rare (may affect up to 1 in 10,000 people):<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>cases of ulceration or&nbsp;perforation&nbsp;of the cornea<\/li><li>severe blisters or flaking of the skin (may indicate&nbsp;Stevens-Johnson&nbsp;syndrome)<\/li><li>inflammation&nbsp;in the colored part of the eye.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Erlotinib STADA<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<br><\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton and blister after EXP.&nbsp;The expiration date is the last day of the specified month.<br><\/p>\n\n\n\n<p>No special storage instructions.<br><\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<p>The active substance is erlotinib.<\/p>\n\n\n\n<p><em>Erlotinib Stada 25 mg film-coated tablets<\/em><\/p>\n\n\n\n<p>Each film-coated tablet contains erlotinib hydrochloride equivalent to 25 mg erlotinib.<\/p>\n\n\n\n<p><em>Erlotinib Stada 100 mg film-coated tablets<\/em><\/p>\n\n\n\n<p>Each film-coated tablet contains erlotinib hydrochloride equivalent to 100 mg erlotinib.<\/p>\n\n\n\n<p><em>Erlotinib Stada 150 mg film-coated tablets<\/em><\/p>\n\n\n\n<p>Each film-coated tablet contains erlotinib hydrochloride equivalent to 150 mg erlotinib.<br><\/p>\n\n\n\n<p>Other ingredients are:<\/p>\n\n\n\n<p><em>Tablet core:&nbsp;<\/em>lactose monohydrate, microcrystalline cellulose (E460), sodium starch glycolate Type A, magnesium stearate (E470b).<\/p>\n\n\n\n<p><em>Tablet coating:<\/em>&nbsp;poly (vinyl alcohol) (E1203), titanium dioxide (E171), macrogol 3350 (E1521), talc (E553b), methacrylic acid-ethyl acrylate copolymer (1: 1), type A, sodium bicarbonate.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p><em>Erlotinib Stada 25 mg film-coated tablets:<\/em>&nbsp;White to yellowish, round, biconvex film-coated tablets with \u201c25\u201d engraved on one side.&nbsp;The diameter of the tablet is 6.1 mm \u00b1 5%<br><\/p>\n\n\n\n<p><em>Erlotinib Stada 100 mg film-coated tablets:<\/em>&nbsp;White to yellowish, round, biconvex film-coated tablets with \u201c100\u201d engraved on one side.&nbsp;The diameter of the tablet is 8.9 mm \u00b1 5%<br><\/p>\n\n\n\n<p><em>Erlotinib Stada 150 mg film-coated tablets:<\/em>&nbsp;White to yellowish, round, biconvex film-coated tablets with \u201c150\u201d engraved on one side.&nbsp;The diameter of the tablet is 10.5 mm \u00b1 5%<\/p>\n\n\n\n<p>The tablets are available in blisters of 30, 90 and 100 tablets or 30&#215;1, 90&#215;1, or 100&#215;1 tablets (single-dose blisters), packaged in cartons.<br><\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p>STADA Arzneimittel AG<\/p>\n\n\n\n<p>Stadastrasse 2-18<\/p>\n\n\n\n<p>61118 Bad Vilbel<\/p>\n\n\n\n<p>Germany<br><\/p>\n\n\n\n<p><strong>Other manufacturers<\/strong><\/p>\n\n\n\n<p>Remedica Ltd<\/p>\n\n\n\n<p>Aharnon Street, Limassol Industrial Estate<\/p>\n\n\n\n<p>3056 Limassol<\/p>\n\n\n\n<p>Cyprus<br><\/p>\n\n\n\n<p>Centrafarm Services BV<\/p>\n\n\n\n<p>New Donk 9<\/p>\n\n\n\n<p>4879 AC Etten-Leur<\/p>\n\n\n\n<p>Netherlands<br><\/p>\n\n\n\n<p>STADAPHARM GmbH<\/p>\n\n\n\n<p>Stadastrasse 2-18<\/p>\n\n\n\n<p>61118 Bad Vilbel<\/p>\n\n\n\n<p>Germany<br><\/p>\n\n\n\n<p><strong>Local representative<\/strong><\/p>\n\n\n\n<p>STADA Nordic ApS<\/p>\n\n\n\n<p>Marielundvej 46A<\/p>\n\n\n\n<p>2730 Herlev<\/p>\n\n\n\n<p>Denmark<br><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Erlotinib Stada contains the active substance erlotinib. Erlotinib Stada is a medicine used to treat cancer by preventing the activity of a protein called epidermal growth factor receptor (EGFR). This protein is known to be involved in the growth and spread of cancer cells.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2205,2200],"tags":[3897,3898,3903,3904,2213,2211,3899,3905],"class_list":["post-8312","post","type-post","status-publish","format-standard","hentry","category-e","category-medicines","tag-erlotinib","tag-erlotinib-side-effects","tag-erlotinib-stada","tag-erlotinib-stada-side-effects","tag-medicines","tag-tablets","tag-what-is-erlotinib","tag-what-is-erlotinib-stada"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8312","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=8312"}],"version-history":[{"count":3,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8312\/revisions"}],"predecessor-version":[{"id":10418,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8312\/revisions\/10418"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=8312"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=8312"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=8312"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}