{"id":8282,"date":"2021-03-10T07:26:16","date_gmt":"2021-03-10T07:26:16","guid":{"rendered":"https:\/\/zeepedia.com\/?p=8282"},"modified":"2021-04-27T13:18:36","modified_gmt":"2021-04-27T13:18:36","slug":"eptifibatide-accord","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/eptifibatide-accord\/","title":{"rendered":"Eptifibatide Accord &#8211; Eptifibatide uses, dose and side effects"},"content":{"rendered":"\n<p> 0.75 mg \/ ml solution for infusion\u00a0<br>eptifibatide<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What Eptifibatide Accord is and what it is used for<\/h2>\n\n\n\n<p>Eptifibatide Accord is a platelet aggregation inhibitor.&nbsp;This means that it helps to prevent the platelets from clotting.<br><\/p>\n\n\n\n<p>It is used in adults with signs of severe&nbsp;heart failure&nbsp;defined as spontaneous and recently experienced chest pain with&nbsp;ECG&nbsp;changes or biological changes.&nbsp;It is usually given together with&nbsp;acetylsalicylic acid&nbsp;and unfractionated&nbsp;heparin.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2. What you need to know before using Eptifibatide Accord<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Eptifibatide Accord<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to eptifibatide or any of the other ingredients of this medicine (listed in section 6)<\/li><li>if you have recently had bleeding from the stomach, intestines, bladder, or other organs, for example, if you have seen abnormal co-bleeding in the stool or urine (except menstrual bleeding) in the last 30 days<\/li><li>if you have had a stroke in the last 30 days or some form of cerebral hemorrhage (also make sure your doctor knows if you have ever had a stroke)<\/li><li>if you have had a brain tumor or any disease that affects the blood vessels in the brain<\/li><li>if you have undergone major surgery or suffered a serious injury in the last 6 weeks<\/li><li>if you have or have had bleeding problems<\/li><li>if you have or have had coagulation disorders or a low&nbsp;platelet count<\/li><li>if you have or have had severe&nbsp;hypertension&nbsp;(high&nbsp;blood pressure&nbsp;)<\/li><li>if you have or have had severe kidney or liver problems<\/li><li>if you have been treated with another medicine of the same type as Eptifibatide Accord.<\/li><\/ul>\n\n\n\n<p>Tell your doctor if you have had any of these conditions.&nbsp;If you have any further questions, ask your doctor, hospital pharmacist, or nurse.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Eptifibatide Accord is only recommended for use in adult inpatients in cardiology departments.<\/li><li>Eptifibatide Accord is not intended for use in children or adolescents below 18 years.<\/li><li>Before and during treatment with Eptifibatide Accord, blood tests will be taken as a precautionary measure to limit the risk of unexpected bleeding.<\/li><li>When you receive Eptifibatide Accord, you will be closely monitored for signs of unusual or unexpected bleeding.<\/li><\/ul>\n\n\n\n<p>Talk to your doctor, hospital pharmacist, or nurse before using Eptifibatide Accord.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Eptifibatide Accord<\/h2>\n\n\n\n<p>To avoid the risk of&nbsp;interacting&nbsp;with other medicines, tell your doctor, hospital pharmacist, or nurse if you are taking, have recently taken, or might take any other medicines, including medicines obtained without a prescription.&nbsp;Particularly:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>blood thinners (oral&nbsp;anticoagulants&nbsp;) or<\/li><li>medicines that prevent the blood from clotting, including&nbsp;warfarin, dipyridamole, ticlopidine,&nbsp;acetylsalicylic acid&nbsp;(except for those that you may receive as part of the Eptifibatide Accord treatment).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n<p>Eptifibatide Accord is not usually recommended for use during pregnancy.&nbsp;Tell your doctor if you are pregnant, think you may be pregnant, or are planning to have a baby.&nbsp;Your doctor will weigh the benefits for you against the risks to your baby when using Eptifibatide Accord during your pregnancy.<br><\/p>\n\n\n\n<p>If you are breast-feeding, you should stop breastfeeding during the treatment period.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. How to use Eptifibatide Accord<\/h2>\n\n\n\n<p>Eptifibatide Accord is given into a vein by direct&nbsp;injection&nbsp;followed by an&nbsp;infusion(drip solution).&nbsp;Dose&nbsp;one is calculated according to your body weight.&nbsp;The recommended&nbsp;dose&nbsp;is 180 micrograms\/kg given as a&nbsp;bolus&nbsp;(rapid&nbsp;intravenous injection&nbsp;), followed by an&nbsp;infusion&nbsp;(drip solution) of 2 micrograms\/kg\/minute for up to 72 hours.&nbsp;If you have any kidney disease, the&nbsp;dose&nbsp;may be reduced to 1 microgram\/kg\/minute.<br><\/p>\n\n\n\n<p>If catheterization (PCI) procedures are performed during treatment with Eptifibatide Accord, the intravenous solution may be given for up to 96 hours.<br><\/p>\n\n\n\n<p>You must also receive&nbsp;acetylsalicylic acid&nbsp;and&nbsp;heparin&nbsp;(unless&nbsp;contraindicated&nbsp;in your case).<br><\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor, hospital pharmacist, or nurse.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects,&nbsp;although not everybody gets them.<br><\/p>\n\n\n\n<p><em><strong>A very common&nbsp;side effect<\/strong><\/em><\/p>\n\n\n\n<p><em>Occurs in more than 1 in 10 individuals<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>minor or major bleeding (eg blood in the urine, blood in the stool, blood in connection with vomiting or bleeding in connection with surgery)<\/li><li>anemia&nbsp;(decreased number of&nbsp;red blood cells&nbsp;).<\/li><\/ul>\n\n\n\n<p><strong><em>Common&nbsp;side effect<\/em><\/strong><\/p>\n\n\n\n<p><em>Occurs in up to 1 in 10 individuals<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>inflammation&nbsp;of blood vessels.<\/li><\/ul>\n\n\n\n<p><strong><em>Uncommon&nbsp;side effect<\/em><\/strong><\/p>\n\n\n\n<p><em>Occurs in up to 1 in 100 individuals<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>decreased&nbsp;platelet count&nbsp;(&nbsp;blood cells&nbsp;needed for blood coagulation)<\/li><li>reduced blood supply to the brain.<\/li><\/ul>\n\n\n\n<p><strong><em>A very rare&nbsp;side effect<\/em><\/strong><\/p>\n\n\n\n<p><em>Occurs in up to 1 in 10,000 individuals<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>severe bleeding (eg bleeding inside the abdomen, brain, or lungs)<\/li><li>bleeding leading to death<\/li><li>a sharp decrease in the number of&nbsp;platelets&nbsp;(&nbsp;blood cells&nbsp;needed for blood coagulation)<\/li><li>skin rash (&nbsp;hives&nbsp;)<\/li><li>sudden severe&nbsp;allergic reaction.<\/li><\/ul>\n\n\n\n<p>If you notice any signs of bleeding, contact your doctor, hospital pharmacist, or nurse immediately.&nbsp;In very rare cases, bleeding has become severe and even fatal.&nbsp;Precautions to prevent this from happening to include blood tests and close checks performed by the healthcare professional who cares for you.<\/p>\n\n\n\n<p>If you get a severe&nbsp;allergic reaction&nbsp;or hives, contact your doctor, hospital pharmacist, or nurse immediately.<br><\/p>\n\n\n\n<p>Other&nbsp;side effects&nbsp;that may occur in patients who require this type of treatment include those associated with the disease you are being treated for, such as rapid or irregular heartbeat, low&nbsp;blood pressure,&nbsp;shock,&nbsp;or cardiac arrest.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Eptifibatide Accord<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<br><\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton and vial after EXP.&nbsp;The expiration date is the last day of the specified month.<br><\/p>\n\n\n\n<p>Store in a refrigerator (2 \u00b0 C &#8211; 8 \u00b0 C).<br><\/p>\n\n\n\n<p>Store the infusion bottle in the outer carton.&nbsp;Sensitive to light.&nbsp;However, the Eptifibatide Accord solution does not need to be protected from light during&nbsp;administration&nbsp;<br><\/p>\n\n\n\n<p>The contents of the bottle should be checked before use.<\/p>\n\n\n\n<p>Do not use this medicine if the solution contains particles or is discolored.<br><\/p>\n\n\n\n<p>Any remaining medicine in the bottle should be discarded.<br><\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your hospital pharmacist or pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is eptifibatide.Eptifibatide Accord 0.75 mg \/ ml: Each ml of&nbsp;solution for infusion&nbsp;contains 0.75 mg of eptifibatide.&nbsp;One 100 ml&nbsp;vial&nbsp;contains 75 mg of eptifibatide.<\/li><li>The other ingredients are citric acid monohydrate, sodium hydroxide, and water for injections.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>Eptifibatide Accord 0.75 mg \/ ml&nbsp;solution for infusion&nbsp;: 100 ml&nbsp;vial&nbsp;, pack of one&nbsp;vial&nbsp;.<br><\/p>\n\n\n\n<p>Eptifibatide Accord 0.75 mg\/ml: The clear, colorless liquid is supplied in a 100 ml&nbsp;glass&nbsp;infusion&nbsp;bottle, which is closed with a butyl rubber stopper and sealed with a removable aluminum closure.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p><em>Marketing Authorisation Holder:<\/em><\/p>\n\n\n\n<p>Accord Healthcare SLU<\/p>\n\n\n\n<p>World Trade Center, Moll de Barcelona, \u200b\u200bs \/ n,<\/p>\n\n\n\n<p>Edifici Est 6\u00aa planta,<\/p>\n\n\n\n<p>08039 Barcelona,<\/p>\n\n\n\n<p>Spain<br><\/p>\n\n\n\n<p><em>Manufacturer:<\/em><\/p>\n\n\n\n<p>Accord Healthcare Limited<\/p>\n\n\n\n<p>Sage House<\/p>\n\n\n\n<p>319, Pinner Road, Harrow<\/p>\n\n\n\n<p>Middlesex HA1 4HF<\/p>\n\n\n\n<p>UK<br><\/p>\n\n\n\n<p>Wessling Hungary Kft<\/p>\n\n\n\n<p>Foot out 56, Budapest 1047,<\/p>\n\n\n\n<p>Hungary<br><\/p>\n\n\n\n<p>Accord Healthcare Polska Sp.z oo,<\/p>\n\n\n\n<p>ul.&nbsp;Lutomierska 50,95-200 Pabianice, Poland<br><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Eptifibatide Accord is a platelet aggregation inhibitor. This means that it helps to prevent the platelets from clotting.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2205,2200],"tags":[3962,3965,3967,3964,2213,3963,3966],"class_list":["post-8282","post","type-post","status-publish","format-standard","hentry","category-e","category-medicines","tag-eptifibatide","tag-eptifibatide-accord","tag-eptifibatide-accord-side-effects","tag-eptifibatide-side-effects","tag-medicines","tag-what-is-eptifibatide","tag-what-is-eptifibatide-accord"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8282","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=8282"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8282\/revisions"}],"predecessor-version":[{"id":10445,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8282\/revisions\/10445"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=8282"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=8282"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=8282"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}