{"id":8242,"date":"2021-03-08T07:04:22","date_gmt":"2021-03-08T07:04:22","guid":{"rendered":"https:\/\/zeepedia.com\/?p=8242"},"modified":"2021-04-28T07:32:16","modified_gmt":"2021-04-28T07:32:16","slug":"eplerenone-teva","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/eplerenone-teva\/","title":{"rendered":"Eplerenone Teva &#8211; Eplerenone uses, dose and side effects"},"content":{"rendered":"\n<p> 25 mg and 50 mg\u00a0film-coated tablets\u00a0<br>eplerenone<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What Eplerenone Teva is and what it is used for<\/h2>\n\n\n\n<p>Eplerenone Teva belongs to a group of medicines called selective aldosterone antagonists.&nbsp;These&nbsp;antagonists&nbsp;inhibit the effect of&nbsp;aldosterone, a substance that the body produces to regulate&nbsp;blood pressure&nbsp;and heart function.&nbsp;High levels of&nbsp;aldosterone&nbsp;can cause changes in the body that lead to&nbsp;heart failure.<br><\/p>\n\n\n\n<p>Eplerenone Teva is used to treat your&nbsp;heart failure&nbsp;to prevent deterioration and reduce the number of hospital stays if you have:<br><\/p>\n\n\n\n<ol class=\"wp-block-list\"><li>have had a recent heart attack, in combination with other medicines used to treat your&nbsp;heart failure, or<\/li><li>had persistent, mild symptoms despite the treatment you have received so far.<\/li><\/ol>\n\n\n\n<p>Eplerenone contained in Eplerenone Teva may also be approved for the treatment of other conditions not mentioned in this product information.&nbsp;Ask your doctor, pharmacist, or other healthcare professional if you have any further questions, and always follow their instructions.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before using Eplerenone Teva<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not take Eplerenone Teva:<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to eplerenone or any of the other ingredients of this medicine (listed in section 6)<\/li><li>if you have elevated levels of&nbsp;potassium&nbsp;in your blood (hyperkalemia)<\/li><li>if you are taking&nbsp;diuretics&nbsp;that reduce the body&#8217;s excess fluid (potassium-sparing&nbsp;diuretics&nbsp;)<\/li><li>if you have severe kidney disease<\/li><li>if you have severe liver disease<\/li><li>if you are taking medicines for fungal infections (&nbsp;ketoconazole&nbsp;or itraconazole)<\/li><li>if you take antiviral drugs to treat&nbsp;HIV&nbsp;&#8211;&nbsp;infection&nbsp;(nelfinavir or ritonavir)<\/li><li>if you are taking&nbsp;antibiotics&nbsp;to treat bacterial&nbsp;infections&nbsp;(clarithromycin or telithromycin)<\/li><li>if you are taking nefazodone to treat depression<\/li><li>if you are taking medicines to treat certain heart diseases or high&nbsp;blood pressure(so-called angiotensin-converting&nbsp;enzyme&nbsp;(ACE) inhibitors and an angiotensin receptor blocker (ARB)) together.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before taking Eplerenone Teva:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>if you have kidney or liver disease (see also \u201cDo not take Eplerenone Teva\u201d)<\/li><li>if you are taking lithium (commonly used for depressive illness, also known as&nbsp;bipolar disorder&nbsp;)<\/li><li>if you are taking tacrolimus or ciclosporin (to treat skin conditions such as&nbsp;psoriasis&nbsp;or&nbsp;eczema&nbsp;and to prevent organ rejection after organ transplantation).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>The safety and efficacy of eplerenone in children and adolescents have not been established.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Eplerenone Teva<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>itraconazole or&nbsp;ketoconazole&nbsp;(for the treatment of fungal infections), ritonavir, nelfinavir (antiviral drugs against&nbsp;HIV&nbsp;&#8211;&nbsp;infection&nbsp;), clarithromycin, telithromycin (drugs for bacterial infections), or nefazodone (depression) when these drugs may reduce degradation of Eplerenone Teva, thereby extending its effect in the body.<\/li><li>potassium-sparing&nbsp;diuretics&nbsp;(medicines that help to reduce the body&#8217;s excess fluid) and potassium supplements (salt tablets) as these medicines increase the risk of elevated levels of&nbsp;potassium&nbsp;in the blood.<\/li><li>angiotensin-converting&nbsp;enzyme&nbsp;(ACE) inhibitors and angiotensin receptor blockers (ARBs) together (which are used to treat high&nbsp;blood pressure, heart disease, or certain kidney conditions) as these medicines may increase the risk of high levels of&nbsp;potassium&nbsp;in the blood.<\/li><\/ul>\n\n\n\n<ul class=\"wp-block-list\"><li>lithium (commonly used to treat manic-depressive illness, also called&nbsp;bipolar disorder&nbsp;).&nbsp;The use of lithium in combination with&nbsp;diuretics&nbsp;and&nbsp;ACE inhibitors(used to treat high&nbsp;blood pressure&nbsp;and heart disease) has been shown to cause high levels of lithium in the blood, which can cause side effects: loss of appetite;&nbsp;visual disturbances;&nbsp;fatigue;&nbsp;muscle weakness;&nbsp;muscle twitching.<\/li><li>ciclosporin or tacrolimus (to treat skin conditions such as&nbsp;psoriasis&nbsp;or&nbsp;eczema, and to prevent organ rejection after organ transplantation).&nbsp;These drugs can cause problems with the kidneys and thus increase the risk of elevated levels of&nbsp;potassium&nbsp;in the blood.<\/li><li>non-steroidal anti-inflammatory drugs (so-called&nbsp;NSAIDs&nbsp;&#8211; painkillers such as&nbsp;ibuprofen&nbsp;used to treat pain, stiffness, and&nbsp;inflammation&nbsp;).&nbsp;These drugs can lead to kidney problems and thus increase the risk of elevated levels of&nbsp;potassium&nbsp;in the blood.<\/li><li>Trimethoprim (a medicine used to treat bacterial infections) may increase the risk of high levels of&nbsp;potassium&nbsp;in the blood.<\/li><li>alpha-1 receptor blockers, such as&nbsp;Prazosin or alfuzosin (used for high&nbsp;blood pressure&nbsp;and certain prostate diseases) can cause a drop in blood pressure and dizziness when standing up.<\/li><li>tricyclic antidepressants&nbsp;such as&nbsp;amitriptyline or amoxapine (for the treatment of depression), antipsychotics (also called&nbsp;neuroleptics&nbsp;) such as chlorpromazine or&nbsp;haloperidol&nbsp;(for the treatment of mental illness), amifostine (used during cancer treatment), and baclofen (for the treatment of muscle spasms).&nbsp;These medicines can cause a drop in blood pressure and dizziness when standing up.<\/li><li>Glucocorticoids, such as&nbsp;hydrocortisone&nbsp;or prednisone (used to treat&nbsp;inflammation&nbsp;and certain skin conditions) and tetracosactide (used mainly to diagnose and treat&nbsp;adrenal cortex&nbsp;disorders&nbsp;) may reduce the blood pressure-lowering effect of Eplerenone Teva.<\/li><li>digoxin&nbsp;(for heart disease).&nbsp;The levels of&nbsp;digoxin&nbsp;in the blood can increase when taken together with Eplerenone Teva.<\/li><li>warfarin&nbsp;(used to prevent blood clots): caution is warranted during warfarin treatment as high levels of&nbsp;warfarin&nbsp;in the blood may cause changes in the effect of Eplerenone Teva in the body.<\/li><li>erythromycin (used to treat bacterial infections), saquinavir (antiviral drugs for the treatment of&nbsp;HIV&nbsp;&#8211;&nbsp;infection&nbsp;),&nbsp;fluconazole&nbsp;(for the treatment of fungal infections),&nbsp;amiodarone,&nbsp;diltiazem,&nbsp;and verapamil (for cardiac problems, high&nbsp;blood pressure) decreases degradation of eplerenone and thus prolonging Eplerenone Teva effect in the body.<\/li><li>St. John&#8217;s wort&nbsp;(herbal medicine), rifampicin (for the treatment of bacterial infections), carbamazepine,&nbsp;phenytoin,&nbsp;and phenobarbital (medicines for&nbsp;epilepsy, among others&nbsp;) can increase the breakdown of eplerenone and thus reduce its effect.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Eplerenone Teva with food and drink<\/h2>\n\n\n\n<p>Eplerenone Teva can be taken with or without food.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breast-feeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.&nbsp;The effect of eplerenone during human pregnancy has not been studied.<br><\/p>\n\n\n\n<p>It is not known whether eplerenone is excreted in human breast milk.&nbsp;Discuss with your doctor before deciding whether to stop breastfeeding or stop taking the medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>You may feel dizzy after taking Eplerenone Teva.&nbsp;If this happens, do not drive or use any tools or machines.<br><\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.&nbsp;One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or&nbsp;side effects.&nbsp;Descriptions of these effects and&nbsp;side effects&nbsp;can be found in other sections.&nbsp;Read all the information in this leaflet for guidance.&nbsp;If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Eplerenone Teva contains lactose monohydrate<\/h2>\n\n\n\n<p>Eplerenone Teva contains&nbsp;lactose monohydrate&nbsp;(a sugar).&nbsp;If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. How to use Eplerenone Teva<\/h2>\n\n\n\n<p>Always take this medicine exactly as your doctor or pharmacist has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<br><\/p>\n\n\n\n<p>Eplerenone Teva can be taken with food or on an empty stomach.&nbsp;Swallow the tablets whole along with a copious amount of liquid.<br><\/p>\n\n\n\n<p>Eplerenone Teva is normally given with other&nbsp;heart failure&nbsp;medicines, e.g.&nbsp;beta-blockers.&nbsp;The recommended starting dose is one 25 mg tablet once a day, which after about 4 weeks is increased to 50 mg once a day (either as a 50 mg tablet or two 25 mg tablets).&nbsp;The maximum&nbsp;dose&nbsp;is 50 mg daily.<br><\/p>\n\n\n\n<p>Potassium levels in the blood should be monitored before treatment with Eplerenone Teva, during the first week of treatment, and one month after starting a treatment or changing the&nbsp;dose.&nbsp;Dose&nbsp;one may need to be adjusted by your doctor, depending on the potassium levels in your blood.<br><\/p>\n\n\n\n<p>If you have mild renal impairment, you should start with a 25 mg tablet every day.&nbsp;And if you have moderate kidney function, you should start with a 25 mg tablet every other day.&nbsp;These&nbsp;doses&nbsp;can be adjusted if your doctor recommends it depending on the levels of&nbsp;potassium&nbsp;in&nbsp;your&nbsp;blood.<br><\/p>\n\n\n\n<p>Eplerenone Teva is not recommended for patients with severe renal impairment.<br><\/p>\n\n\n\n<p>The starting dose does not need to be adjusted in patients with mild to moderate hepatic impairment.&nbsp;If you have liver or kidney problems, your blood potassium levels may need to be checked more often (see also \u201cDo not take Eplerenone Teva\u201d).<br><\/p>\n\n\n\n<p>Elderly: No adjustment of the starting dose is required.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Use for children and adolescents<\/h2>\n\n\n\n<p>Eplerenone Teva is not recommended for children and adolescents.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you use more Eplerenone Teva then you should &nbsp;<\/h2>\n\n\n\n<p>If you have ingested too much medicine or if e.g.&nbsp;If a child has inadvertently ingested the medicine, contact a doctor, hospital, or the Poison Information Center for risk assessment and advice.<br><\/p>\n\n\n\n<p>If you have taken too much of your medicine, the most likely symptoms will be low&nbsp;blood pressure&nbsp;(may manifest as a &#8220;slight&#8221; feeling in your head, dizziness, blurred vision, weakness,&nbsp;acute&nbsp;unconsciousness) or&nbsp;hyperkalemia, elevated levels of&nbsp;potassium&nbsp;in the blood ( may cause muscle cramps, diarrhea, nausea, dizziness or headache).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to use Eplerenone Teva<\/h2>\n\n\n\n<p>If it is soon time for your next&nbsp;dose, skip the missed tablet and take the next one as usual.&nbsp;Otherwise, take it as soon as you remember, provided it is more than 12 hours until you take the next tablet.&nbsp;Then return to your regular medication.&nbsp;Do not take a double&nbsp;dose&nbsp;to make up for a forgotten tablet.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop using Eplerenone Teva<\/h2>\n\n\n\n<p>It is important to continue taking Eplerenone Teva as&nbsp;prescribed&nbsp;unless your doctor tells you to stop your treatment.<br><\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects, although not everybody gets them.<br><\/p>\n\n\n\n<p>If you experience any of the following<strong>, seek medical attention immediately:<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>swelling of the face, tongue, or throat<\/li><li>difficulty swallowing<\/li><li>hives&nbsp;and difficulty breathing<\/li><\/ul>\n\n\n\n<p>These are symptoms of&nbsp;angioneurotic edema, a less common (may affect up to 1 in 100 people)&nbsp;side effect.<br><\/p>\n\n\n\n<p>Other reported&nbsp;side effects&nbsp;include:<br><\/p>\n\n\n\n<p><strong>Common<\/strong>&nbsp;(may affect up to 1 in 10 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>high potassium levels in the blood (symptoms include muscle cramps, diarrhea, nausea, dizziness, or headache)<\/li><li>fainting<\/li><li>dizziness<\/li><li>increased level of&nbsp;cholesterol&nbsp;in the blood<\/li><li>insomnia (difficulty sleeping)<\/li><li>headache<\/li><li>heart problems such as irregular heartbeat and&nbsp;heart failure<\/li><li>cough<\/li><li>constipation<\/li><li>low&nbsp;blood pressure<\/li><li>diarrhea<\/li><li>nausea<\/li><li>vomiting<\/li><li>impaired renal function<\/li><li>rash<\/li><li>itching<\/li><li>back pain<\/li><li>impotence<\/li><li>muscle twitching<\/li><li>increased level of&nbsp;urea&nbsp;in the blood<\/li><li>increased content of&nbsp;creatinine&nbsp;in the blood which may indicate problems with the kidneys<\/li><\/ul>\n\n\n\n<p><strong>Uncommon<\/strong>&nbsp;(may affect up to 1 in 100 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>infection<\/li><li>eosinophilia&nbsp;(increase in certain&nbsp;white blood cells&nbsp;)<\/li><li>decreased&nbsp;sodium&nbsp;levels in the blood<\/li><li>dehydration<\/li><li>increase in&nbsp;triglycerides&nbsp;(blood fats) in the blood<\/li><li>fast heartbeat<\/li><li>inflammation&nbsp;of the gallbladder<\/li><li>lowered&nbsp;blood pressure&nbsp;which can sometimes cause dizziness, e.g.&nbsp;if you get up<\/li><li>thrombosis&nbsp;(blood clot) in the legs<\/li><li>sore throat<\/li><li>gas formation<\/li><li>underactive&nbsp;thyroid gland<\/li><li>elevated blood sugar<\/li><li>the decreased sensation on touch<\/li><li>increased sweating<\/li><li>pain in muscles and bones<\/li><li>feeling sick<\/li><li>kidney inflammation<\/li><li>enlarged breasts in men<\/li><li>changes in certain blood test results<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Eplerenone Teva<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<br><\/p>\n\n\n\n<p>No special storage instructions.<br><\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton and blister after EXP.<br><\/p>\n\n\n\n<p>The expiration date is the last day of the specified month.<br><\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is eplerenone.25 mg: 1 film-coated tablet contains 25 mg eplerenone.50 mg: 1 film-coated tablet contains 50 mg eplerenone.<\/li><li>The other ingredients are&nbsp;lactose monohydrate, microcrystalline cellulose, crospovidone (type A), sodium lauryl sulfate, talc (E553b), and magnesium stearate.&nbsp;The tablet coating contains poly (vinyl alcohol) (E1203), titanium dioxide (E171), macrogol 3350 (E1521), talc (E553b), yellow iron oxide (E172), and red iron oxide (E172).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Film-coated tablets<\/li><li>25 mg: yellow, diamond-shaped, biconvex film-coated tablet, approximately 6.4 mm wide and 7.4 mm long, debossed with &#8220;E25&#8221; on one side and unmarked on the other side.50 mg: yellow, diamond-shaped, biconvex film-coated tablet, approximately 8.0 mm wide and 9.5 mm long, debossed with &#8220;E50&#8221; on one side and unmarked on the other side.<\/li><li>Eplerenone Teva film-coated tablets are available in opaque PVC \/ PVdC \/ Al blisters of 1, 10, 20, 28, 30, 50, 56, 60, 90, 100 or 200 tablets and in opaque PVC \/ PVdC \/ Al perforated unit blisters containing 20&#215;1, 30&#215;1, 50&#215;1, 90&#215;1, 100&#215;1 or 200&#215;1 tablets.&nbsp;25 mg: The tablets are also available in&nbsp;calendar&nbsp;packs of 30 and 100 tablets respectively.&nbsp;50 mg: The tablets are also available in&nbsp;calendar&nbsp;packs of 100 tablets.<\/li><\/ul>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<p><em>Manufacturer:<\/em><\/p>\n\n\n\n<p>TEVA Pharmaceutical Works Private Limited Company<\/p>\n\n\n\n<p>Pallagi Street<\/p>\n\n\n\n<p>4042 Debrecen<\/p>\n\n\n\n<p>Hungary<br><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Eplerenone Teva belongs to a group of medicines called selective aldosterone antagonists. These antagonists inhibit the effect of aldosterone, a substance that the body produces to regulate blood pressure and heart function. High levels of aldosterone can cause changes in the body that lead to heart failure.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2205,2200],"tags":[3996,3998,4002,4004,2213,2211,3997,4003],"class_list":["post-8242","post","type-post","status-publish","format-standard","hentry","category-e","category-medicines","tag-eplerenone","tag-eplerenone-side-effects","tag-eplerenone-teva","tag-eplerenone-teva-side-eccects","tag-medicines","tag-tablets","tag-what-is-eplerenone","tag-what-is-eplerenone-teva"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8242","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=8242"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8242\/revisions"}],"predecessor-version":[{"id":10459,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8242\/revisions\/10459"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=8242"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=8242"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=8242"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}