{"id":8219,"date":"2021-03-08T06:45:55","date_gmt":"2021-03-08T06:45:55","guid":{"rendered":"https:\/\/zeepedia.com\/?p=8219"},"modified":"2022-11-27T17:13:25","modified_gmt":"2022-11-27T17:13:25","slug":"epidyolex","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/epidyolex\/","title":{"rendered":"Epidyolex &#8211; Cannabidiol Uses, Dose, And Side Effects"},"content":{"rendered":"\n<p><strong>Epidyolex 100 mg\/ml\u00a0Oral\u00a0Cannabidiol\u00a0Solution<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What Epidyolex Is And What Is Epidyolex Used For<\/h2>\n\n\n\n<p>Epidyolex contains cannabidiol, a drug that can be used to treat&nbsp;epilepsy, a condition that causes seizures.<\/p>\n\n\n\n<p>Epidyolex is used in combination with clobazam, or in combination with clobazam and other drugs against\u00a0<strong><a href=\"https:\/\/zeepedia.com\/diseases\/brain-and-nerves\/epilepsy\/\">Epilepsy<\/a><\/strong>, for the treatment of seizures occurring at two rare diseases<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Dravet syndrome<\/li><li>Lennox-Gastaut syndrome<\/li><\/ul>\n\n\n\n<p>It can be used for adults, adolescents, and children from 2 years of age.<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><a href=\"https:\/\/amzn.to\/3EGuP67\" rel=\"noopener\"><img loading=\"lazy\" decoding=\"async\" width=\"290\" height=\"252\" src=\"https:\/\/zeepedia.com\/wp-content\/uploads\/2022\/11\/epidyolex.png\" alt=\"Epidyolex\" class=\"wp-image-36418\"\/><\/a><figcaption><strong>Epidyolex<\/strong><\/figcaption><\/figure><\/div>\n\n\n<h2 class=\"wp-block-heading\">2. What You Or The Patient Need To Know Before Taking Epidyolex<\/h2>\n\n\n\n<p>Do Not Take Epidyolex<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>If you are allergic to cannabidiol or any of the other ingredients of <em><span style=\"text-decoration: underline;\">Epidyolex<\/span><\/em> (listed in section 6).<\/li><li>If your doctor determines that you have certain abnormal liver values \u200b\u200bon blood tests.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings And Cautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before taking Epidyolex, or during treatment, if:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>You have or have had liver problems.&nbsp;Your doctor may need to change the&nbsp;<em>dose of Epidyolex<\/em> or you may decide that Epidyolex is not suitable for you. Your doctor may take blood samples to check your liver before and during treatment, as Epidyolex may cause liver problems.&nbsp;If the liver is not working properly, treatment may need to be stopped.<\/li><li>You notice any unusual changes in your mood or behavior, or if you have thoughts of harming yourself or committing suicide.&nbsp;<strong>Contact your doctor or go to the hospital&nbsp;immediately<\/strong>&nbsp;(see section 4).<\/li><li>Epidyolex makes you sleepy.&nbsp;Do not drive a car or other vehicles, do not use machines or engage in activities that require you to be attentive and have good motor skills, e.g.&nbsp;cycling, until you know how Epidyolex affects you.<\/li><li>You abruptly stop taking Epidyolex.<\/li><li>Your seizures come more often or if you have a severe seizure while taking Epidyolex.&nbsp;<strong>Contact your&nbsp;doctor or go to the hospital immediately.<\/strong><\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Children And Young People<\/h2>\n\n\n\n<p>Epidyolex must not be given to children under 2 years of age as there is no information on its use in children under 2 years of age.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other Medicines And Epidyolex<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.&nbsp;Taking Epidyolex with certain other medicines can cause&nbsp;side effects and the medicines can affect each other.&nbsp;Do not start or stop taking other medicines without first talking to a doctor or pharmacist.<\/p>\n\n\n\n<p>Tell your doctor if you are taking any of the following medicines as the&nbsp;E<em>pidyolex dosage<\/em>&nbsp;may need to be adjusted:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Other drugs for&nbsp;epilepsy, e.g.&nbsp; <ul><li>Carbamazepine<\/li><li>Clobazam<\/li><li>Lamotrigine<\/li><li>Lorazepam<\/li><li>Midazolam<\/li><li>Phenytoin<\/li><li>Stiripentol<\/li><li>Valproate&nbsp;used for seizures<\/li><\/ul><\/li><li>Heartburn medicines (acid reflux)<\/li><li>Omeprazole<\/li><li>Mitotane (for the treatment of&nbsp;tumors&nbsp;in the adrenal glands)<\/li><li>Morphine or diflunisal (painkillers)<\/li><li>Efavirenz (for the treatment of HIV \/ AIDS)<\/li><li>Theophylline (for the treatment of&nbsp;asthma&nbsp;)<\/li><li>Caffeine (medicine for babies who need help with breathing)<\/li><li>Propofol (anesthetic\/sedative used in surgery)<\/li><li>Simvastatin, fenofibrate, gemfibrozil (to lower&nbsp;cholesterol&nbsp;and blood fats)<\/li><li>Enzalutamide (for the treatment of prostate <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/getting-a-cancer-message\/\">cancer<\/a>)<\/li><li>Bupropion (to help stop smoking or treat obesity)<\/li><li>St. John&#8217;s wort&nbsp;(&nbsp;<em>Hypericum perforatum<\/em>&nbsp;) (an herbal medicine used to treat mild anxiety)<\/li><li>Drugs for the treatment of bacterial infections, e.g.<ul><li>Rifampin<\/li><li>Clarithromycin<\/li><li>Erythromycin<\/li><\/ul><\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Epidyolex With Food<\/h2>\n\n\n\n<p>Always take Epidyolex exactly as your doctor has told you, always take it with or without food.&nbsp;This also applies to diets with high-fat meals (so-called ketogenic diets).&nbsp;(See also section 3 \u201cHow to take Epidyolex\u201d).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, Breastfeeding, And Fertility<\/h2>\n\n\n\n<p>If you are pregnant, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.&nbsp;You should only take Epidyolex during pregnancy if your doctor determines that the benefits of treatment outweigh the risks.<\/p>\n\n\n\n<p>You should not breastfeed while taking Epidyolex as Epidyolex is likely to pass into breast milk.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving And Using Machines<\/h2>\n\n\n\n<p>Talk to your doctor about driving or using machines, or if children should engage in activities such as cycling or other sports, as this may make you drowsy.<\/p>\n\n\n\n<p>You should not drive, use machines or engage in activities that require attention and good motor skills until you know that your ability to do so is not affected.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Epidyolex Contains Sesame Oil, Alcohol (Ethanol), And Strawberry Flavors (Including Benzyl Alcohol)<\/h2>\n\n\n\n<p>Epidyolex contains refined sesame oil which in rare cases may cause severe allergic reactions.<\/p>\n\n\n\n<p><strong>Epidyole<\/strong> contains 10 vol%&nbsp;ethanol&nbsp;(alcohol), ie&nbsp;up to 700 mg per&nbsp;dose&nbsp;(for an adult weighing 70 kg), equivalent to 14 milliliters (ml) of beer or 6 ml of wine per&nbsp;dose.&nbsp;May be harmful to people suffering from alcoholism.&nbsp;The alcohol content should be paid attention to by pregnant women, children, and high-risk groups such as patients with liver disease.<\/p>\n\n\n\n<p>In children under 6 years of age, alcohol can have effects such as <\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Drowsiness<\/li><li>Behavioral changes<\/li><li>Concentration problems<\/li><li>Difficulty participating in school activities.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">How To Take Epidyolex<\/h2>\n\n\n\n<p>Always take Epidyolex exactly as your doctor has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p>Epidyolex is an&nbsp;oral&nbsp;solution (a liquid to be swallowed).&nbsp;Your doctor and pharmacist will tell you how much (number of milliliters) Epidyolex to take each day, how many times a day to take it, and which&nbsp;syringe&nbsp;to use for your&nbsp;dose&nbsp;(1 ml or 5 ml).<\/p>\n\n\n\n<p>Your doctor will calculate the <strong>Epidyolex dosage<\/strong>&nbsp;based on your body weight.&nbsp;You can start with a low&nbsp;dose&nbsp;which your doctor will then gradually increase.&nbsp;Contact your doctor if you are not sure how much to take or if you think your&nbsp;<em>dose of Epidyolex<\/em>&nbsp;needs to be changed.<\/p>\n\n\n\n<p>Taking Epidyolex with food may increase the number of medicines taken up by the body.&nbsp;As far as possible, try to take Epidyolex, in the same way, every day when it comes to meals.&nbsp;Take Epidyolex with or without food every day so that you get the same effect from the medicine every time.<br><\/p>\n\n\n\n<p>Tell your doctor if you have liver problems as your doctor may need to adjust&nbsp;someone.<\/p>\n\n\n\n<p>Do not reduce the&nbsp;E<span style=\"text-decoration: underline;\">pidyolex dosage<\/span>&nbsp;and do not stop taking the medicine unless your doctor tells you to.<\/p>\n\n\n\n<p><strong>How to take Epidyolex orally (by mouth)<\/strong><\/p>\n\n\n\n<p>The package contains the following<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>A bottle of Epidyolex&nbsp;oral&nbsp;solution<\/li><li>A plastic bag with two oral dosing syringes of 1 ml and a bottle adapter<\/li><li>A plastic bag with two oral dosing syringes of 5 ml and a bottle adapter<\/li><\/ul>\n\n\n\n<p>A spare syringe of each size is included in the package in case the first syringe breaks or disappears.<\/p>\n\n\n\n<figure class=\"wp-block-image\"><img decoding=\"async\" src=\"https:\/\/www.fass.se\/imaging\/resources\/5cded19e-91a3-4196-a1f2-2442f1db6f20\" alt=\" \"\/><\/figure>\n\n\n\n<p>1. Open the bag containing the oral dosing syringe you are going to use to measure&nbsp;dose&nbsp;one.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>If your&nbsp;dose&nbsp;is&nbsp;<strong>1 ml (100 mg) or less<\/strong>, use the small 1 ml syringe.<\/li><li>If your&nbsp;dose&nbsp;is&nbsp;<strong>greater than 1 ml (100 mg)<\/strong>, use the larger 5 ml syringe.<\/li><li>If your&nbsp;dose&nbsp;is&nbsp;<strong>greater than 5 ml (500 mg)<\/strong>, you must use the larger 5 ml syringe more than once.&nbsp;In this case, you must keep a close eye on how many times you have filled the syringe (eg by dotting each 5 ml&nbsp;dose&nbsp;) so that you take the correct&nbsp;dose.<\/li><\/ul>\n\n\n\n<p>You must use the correct dosing syringe to measure&nbsp;dose&nbsp;one.&nbsp;Your doctor or pharmacist will tell&nbsp;you&nbsp;which&nbsp;syringe&nbsp;to use for the&nbsp;prescribed&nbsp;dose.&nbsp;Follow the instructions of your doctor or pharmacist.&nbsp;The bag containing the other syringes and the adapter (ie those you do not need for your&nbsp;dosing&nbsp;) should be discarded according to the instructions unless&nbsp;your&nbsp;doctor or pharmacist tells you to save both syringe sizes until you have reached your escalated&nbsp;dose.<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter\"><img decoding=\"async\" src=\"https:\/\/www.fass.se\/imaging\/resources\/574f335b-f67f-4fc3-a14d-982347af1a74\" alt=\" \"\/><\/figure><\/div>\n\n\n<p>2. Remove the child-resistant cap from the bottle by pushing it downwards while turning it counterclockwise.<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter\"><img decoding=\"async\" src=\"https:\/\/www.fass.se\/imaging\/resources\/994f421f-de67-4530-bac9-a5f79be0fb9f\" alt=\" \"\/><\/figure><\/div>\n\n\n<p>3. Push the bottle adapter firmly into the neck of the bottle.&nbsp;Make sure it is fully inserted.&nbsp;The adapter may come loose and cause suffocation if not fully inserted.<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter\"><img decoding=\"async\" src=\"https:\/\/www.fass.se\/imaging\/resources\/08c30e89-4142-4e62-aea1-29988462a0c6\" alt=\" \"\/><\/figure><\/div>\n\n\n<p>4. Press down on the tip of the dosing syringe you are going to use in the bottle adapter.&nbsp;Leave the syringe in place and turn the bottle upside down.<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter\"><img decoding=\"async\" src=\"https:\/\/www.fass.se\/imaging\/resources\/34de0f74-69b9-40fc-8d84-9dc7a0657f0a\" alt=\" \"\/><\/figure><\/div>\n\n\n<p>5. Slowly pull the plunger out of the syringe so that the amount of solution (number of ml) needed is drawn into the syringe.&nbsp;The end of the plunger should be level with the volume marking on the syringe, see the picture.<\/p>\n\n\n\n<p>If there is an air bubble in the syringe, push the liquid back into the bottle, still with the bottle upside down.&nbsp;Then repeat step 5 until the bubble is gone.<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter\"><img decoding=\"async\" src=\"https:\/\/www.fass.se\/imaging\/resources\/79137c25-8c52-4134-84c8-8a2915356a24\" alt=\" \"\/><\/figure><\/div>\n\n\n<p>6. Turn the bottle over again and carefully remove the syringe from the adapter.<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter\"><img decoding=\"async\" src=\"https:\/\/www.fass.se\/imaging\/resources\/7d63f182-4cee-4114-b279-b9ee88a2107e\" alt=\" \"\/><\/figure><\/div>\n\n\n<p>7. Place the syringe tip against the inside of the cheek and gently press on the plunger so that the medicine is sprayed out.&nbsp;Do not press hard on the plunger.&nbsp;Do not aim the medicine far into the mouth or throat.<\/p>\n\n\n\n<p>If&nbsp;dose&nbsp;one is more than 5 ml, repeat steps 4 to 7 for the remaining&nbsp;dose&nbsp;one.&nbsp;Use the 5 ml syringe.<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter\"><img decoding=\"async\" src=\"https:\/\/www.fass.se\/imaging\/resources\/53590000-3d6c-4004-9efc-4bbe062d8b0d\" alt=\" \"\/><\/figure><\/div>\n\n\n<p>8. Screw the child-resistant cap back onto the bottle firmly by turning it clockwise.&nbsp;The bottle adapter does not need to be removed, the lid fits on top of the adapter.<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter is-resized\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.fass.se\/imaging\/resources\/57415b63-337c-4a32-b837-8885a747c802\" alt=\" \" width=\"253\" height=\"262\"\/><\/figure><\/div>\n\n\n<p>9. Fill a glass or mug with warm soapy water and clean the dosing syringe by pulling the water in and out using the plunger.<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter is-resized\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.fass.se\/imaging\/resources\/cf65f58f-f555-4b88-bd0a-bba736a675bc\" alt=\" \" width=\"461\" height=\"433\"\/><\/figure><\/div>\n\n\n<p>10. Pull the plunger completely out of the syringe body and rinse both parts under the tap.&nbsp;Do not place the dosing syringe in the dishwasher.<br><\/p>\n\n\n\n<p>Shake off the water from both parts and let them air dry for the next use.&nbsp;Make sure that the dosing syringe is completely dry before using it again, otherwise, it may make the solution look cloudy if water enters the bottle.<br><\/p>\n\n\n\n<p>If the solution in the bottle has become cloudy, it does not affect its effect.&nbsp;Continue to use the medicine as usual.<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter is-resized\"><img loading=\"lazy\" decoding=\"async\" src=\"https:\/\/www.fass.se\/imaging\/resources\/a8b18cc8-3a80-417a-9627-06c2ae2d8d4f\" alt=\" \" width=\"556\" height=\"380\"\/><\/figure><\/div>\n\n\n<h2 class=\"wp-block-heading\">If You Or Your Patient Have Taken Too Much Epidyolex<\/h2>\n\n\n\n<p>If you have taken more Epidyolex than you should, tell your doctor or pharmacist immediately, or contact your nearest emergency department and take the medicine with you.&nbsp;Signs that you have taken more Epidyolex than you should include diarrhea and drowsiness.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If You Or Your Patient Have Forgotten To Take Epidyolex<\/h2>\n\n\n\n<p>If you miss a&nbsp;dose, do not take a double&nbsp;dose&nbsp;to make up for a forgotten&nbsp;dose.&nbsp;Take the next&nbsp;dose&nbsp;at the usual time.&nbsp;If you miss many&nbsp;doses, talk to your doctor about which&nbsp;dose&nbsp;you should take.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If You Or Your Patient Stop Taking Epidyolex<\/h2>\n\n\n\n<p>Do not reduce the&nbsp;dose&nbsp;and do not stop taking Epidyolex without talking to your doctor first.&nbsp;The doctor explains how to gradually stop taking Epidyolex.<\/p>\n\n\n\n<p>If you have any further questions about the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible Epidyolex Side Effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects, although not everybody gets them.<br><\/p>\n\n\n\n<p>The following&nbsp;E<em>pidyolex side effects<\/em>&nbsp;can be&nbsp;<strong>very serious<\/strong>&nbsp;:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>High liver enzymes (elevated&nbsp;transaminases&nbsp;) in blood samples, which may be signs of liver damage, have been reported in patients taking Epidyolex.<\/li><li>People taking <em>Epidyolexmay<\/em> have thoughts of harming themselves or committing suicide.&nbsp;If you ever have such thoughts, consult a doctor.<\/li><\/ul>\n\n\n\n<p>You may experience the following&nbsp;side effects&nbsp;from this medicine.&nbsp;Talk to a doctor if you get any of the following:<\/p>\n\n\n\n<p><strong>A very common&nbsp;side effect&nbsp;is<\/strong>&nbsp;(can occur in more than 1 in 10):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Drowsiness or drowsiness<\/li><li>Decreased appetite<\/li><li>Diarrhea<\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/cold\/\">Fever<\/a><\/li><li>Fatigue<\/li><li>Vomiting<\/li><\/ul>\n\n\n\n<p><strong>Common&nbsp;adverse&nbsp;Epidyolex side effects<\/strong>&nbsp;(can occur in more than 1 in 100):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Powerlessness<\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/cold\/\">Cold<\/a><\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/sore-throat\/\">Sore throat<\/a><\/li><li>Infection&nbsp;of the respiratory tract (&nbsp;pneumonia,&nbsp;bronchitis&nbsp;)<\/li><li>Blood tests show an increase in certain liver enzymes (which may be a sign of liver damage)<\/li><li>Tremors in all or parts of the body<\/li><li>Bad mood (irritability, aggression)<\/li><li>Difficulty sleeping<\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/cough-in-children\/\">Cough<\/a><\/li><li>Rash<\/li><li>Increased appetite<\/li><li>Weight loss<\/li><li>Dredging<\/li><li>Urinary tract infection<\/li><li>Indignation<\/li><li>Abnormally behaving<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">5. How To Store Epidyolex<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Keep Epidyolex out of the sight and reach of children.<\/li><li>Do not use <span style=\"text-decoration: underline;\">Epidyolex<\/span> after the expiry date which is stated on the bottle.&nbsp;The expiration date is the last day of the specified month.<\/li><li>If there is a solution left in the bottle when more than 8 weeks have passed since it was first opened, it should not be used.<\/li><li>No special storage instructions.<\/li><li>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents Of The Packaging And Other Information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content Declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is cannabidiol.&nbsp;Each ml of&nbsp;oral&nbsp;solution contains 100 mg of cannabidiol.<\/li><li>The other ingredients are refined <ul><li>Sesame oil<\/li><li>Anhydrous&nbsp;ethanol<\/li><li>Sucralose<\/li><li>Strawberry flavoring (including benzyl alcohol)<\/li><\/ul><\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What The Epidyolex Looks Like And The Contents Of The Pack<\/h2>\n\n\n\n<p>Epidyolex is a clear, colorless yellow&nbsp;oral&nbsp;solution.&nbsp;It is packaged in a bottle with a child-resistant cap, together with two identical 5 ml or 1 ml oral dosing syringes, and two bottle adapters used with the syringes.&nbsp;The 5 ml syringes are graduated in 0.1 ml increments and the 1 ml syringes are in 0.05 ml increments.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder And Manufacturer<\/h2>\n\n\n\n<p><strong>Marketing Authorisation Holder<\/strong><\/p>\n\n\n\n<p>GW Pharma (International) BV<\/p>\n\n\n\n<p>Databankweg 26, 3821AL Amersfoort, The Netherlands<\/p>\n\n\n\n<p>info@gwpharm.com<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>GW Pharma (International) BV<\/p>\n\n\n\n<p>Databankweg 26, 3821AL Amersfoort, The Netherlands<\/p>\n\n\n\n<p>info@gwpharm.com<\/p>\n\n\n\n<p>GW Pharma Limited<\/p>\n\n\n\n<p>Kent Science Park, Sittingbourne, Kent, ME9 8AG, UK<\/p>\n\n\n\n<p>info@gwpharm.com<\/p>\n\n\n\n<p><br>Contact the representative of the marketing authorization holder to find out more about this medicine:<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td><strong>Belgium \/ Belgique \/ Belgien<\/strong><\/td><td><strong>Lithuania<\/strong><\/td><\/tr><tr><td>Tel: +31 (0) 337981015<\/td><td>Tel: +31 (0) 337981015<\/td><\/tr><tr><td><strong>Bulgaria<\/strong><\/td><td><strong>Luxembourg \/ Luxemburg<\/strong><\/td><\/tr><tr><td>Phone: +31 (0) 337981015<\/td><td>Tel: +31 (0) 337981015<\/td><\/tr><tr><td><strong>Czech Republic<\/strong><\/td><td><strong>Hungary<\/strong><\/td><\/tr><tr><td>Tel: +31 (0) 337981015<\/td><td>Tel .: +31 (0) 337981015<\/td><\/tr><tr><td><strong>Denmark<\/strong><\/td><td><strong>Malta<\/strong><\/td><\/tr><tr><td>Tel: +31 (0) 337981015<\/td><td>Tel: +31 (0) 337981015<\/td><\/tr><tr><td><strong>Germany<\/strong><\/td><td><strong>The Netherlands<\/strong><\/td><\/tr><tr><td>Tel: +49 (0) 3022957821<\/td><td>Tel: +31 (0) 337981015<\/td><\/tr><tr><td><strong>Eesti<\/strong><\/td><td><strong>Norway<\/strong><\/td><\/tr><tr><td>Tel: +31 (0) 337981015<\/td><td>Tel: +31 (0) 337981015<\/td><\/tr><tr><td><strong>Greece<\/strong><\/td><td><strong>Austria<\/strong><\/td><\/tr><tr><td>:\u0397\u03bb: +31 (0) 337981015<\/td><td>Tel: +31 (0) 337981015<\/td><\/tr><tr><td><strong>Spain<\/strong><\/td><td><strong>Poland<\/strong><\/td><\/tr><tr><td>GW Pharma Spain, SL<\/td><td>Tel .: +31 (0) 337981015<\/td><\/tr><tr><td>Tel: + 34-914197379<\/td><td><br><\/td><\/tr><tr><td><strong>France<\/strong><\/td><td><strong>Portugal<\/strong><\/td><\/tr><tr><td>Tel: +33 (0) 170755854<\/td><td>Tel: +31 (0) 337981015<\/td><\/tr><tr><td><strong>Croatia<\/strong><\/td><td><strong>Romania<\/strong><\/td><\/tr><tr><td>Tel: +31 (0) 337981015<\/td><td>Tel: +31 (0) 337981015<\/td><\/tr><tr><td><strong>Ireland<\/strong><\/td><td><strong>Slovenia<\/strong><\/td><\/tr><tr><td>Tel: +31 (0) 337981015<\/td><td>Tel: +31 (0) 337981015<\/td><\/tr><tr><td><strong>Iceland<\/strong><\/td><td><strong>Slovak Republic<\/strong><\/td><\/tr><tr><td>Phone: +31 (0) 337981015<\/td><td>Tel: +31 (0) 337981015<\/td><\/tr><tr><td><strong>Italy<\/strong><\/td><td><strong>Finland \/ Finland<\/strong><\/td><\/tr><tr><td>GW Pharma Italy SRL<\/td><td>Puh \/ Tel: +31 (0) 337981015<\/td><\/tr><tr><td>Tel: +39 (0) 687501801<\/td><td><br><\/td><\/tr><tr><td><strong>Latvia<\/strong><\/td><td><strong>United Kingdom<\/strong><\/td><\/tr><tr><td>Tel: +31 (0) 337981015<\/td><td>Tel: +44 (0) 1223 238170<\/td><\/tr><\/tbody><\/table><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>Epidyolex is specified for use as an adjunctive remedy of seizures linked with Lennox Gastaut syndrome (LGS) or Dravet syndrome (DS), in combination with clobazam, for patients 2 years of age and older.<\/p>\n","protected":false},"author":2,"featured_media":36418,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"yes","footnotes":""},"categories":[2205,2200],"tags":[4059,4063,4061,4062,4064,4068,4066,4067,2213,4060,4065],"class_list":["post-8219","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-e","category-medicines","tag-cannabidiol","tag-cannabidiol-dose","tag-cannabidiol-side-effects","tag-cannabidiol-uses","tag-epidyolex","tag-epidyolex-dose","tag-epidyolex-side-effects","tag-epidyolex-uses","tag-medicines","tag-what-is-cannabidiol","tag-what-is-epidyolex"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8219","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=8219"}],"version-history":[{"count":68,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8219\/revisions"}],"predecessor-version":[{"id":36423,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8219\/revisions\/36423"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media\/36418"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=8219"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=8219"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=8219"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}