400 mg \/ 100 mg\u00a0film-coated tablets, 200 mg \/ 50 mg film-coated tablets\u00a0
sofosbuvir \/ velpatasvir<\/p>\n\n\n\n
Epclusa is a medicine that contains the active substances sofosbuvir and velpatasvir in a single tablet. It is given to treat a chronic (long-term) viral infection in the liver called hepatitis C, in patients aged 6 years and older, and weighing at least 17 kg.
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The active substances in the medicine work together by blocking two different proteins that the virus needs to grow and reproduce, which makes it possible to permanently remove an infection from the body.
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Epclusa is sometimes taken with another medicine, ribavirin.
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It is very important that you also read the package leaflets for the other medicines that you are taking with Epclusa. If you have any further questions on the use of this product, ask your doctor or pharmacist.
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\u2192<\/strong> If this applies to you, do not take Epclusa but tell your doctor immediately.<\/strong><\/p>\n\n\n\n <\/p>\n\n\n\n If you are currently taking any of the following medicines:<\/strong><\/p>\n\n\n\n Talk to a doctor if you:<\/p>\n\n\n\n Talk to your doctor or pharmacist before taking Epclusa if:<\/p>\n\n\n\n Tell<\/strong> your doctor immediately if<\/strong> you are currently taking, or have taken any medicines for heart problems in the last few months, and your experience during treatment:<\/p>\n\n\n\n Blood tests<\/strong><\/p>\n\n\n\n Your doctor will examine your blood before, during, and after treatment with Epclusa. This is to:<\/p>\n\n\n\n Do not give this medicine to children under 6 years of age or weighing less than 17 kg. The use of Epclusa in patients under 6 years of age has not yet been studied.<\/p>\n\n\n\n Tell<\/strong> your doctor or pharmacist<\/strong> if you are taking, have recently taken, or might take any other medicines. Warfarin and other similar medicines called vitamin K antagonists are used to thin the blood. Your doctor may need to test your blood more often to check your blood’s coagulation ability. The function of your liver may change with the treatment of hepatitis C and may therefore affect other medicines (eg medicines used to suppress your immune system, etc.). Your doctor may need to monitor these other medicines you are taking care and adjustments may need to be made after starting treatment with Epiclusa. If you are not sure, talk to your doctor or pharmacist. Some medicines should not be taken with Epclusa.<\/strong><\/p>\n\n\n\n Tell<\/strong> your doctor or pharmacist<\/strong> if you are taking any of the following medicines:<\/p>\n\n\n\n If you take Epclusa with any of these medicines, the medicines may not work properly or any side effects may get worse. Your doctor may need to give you another medicine or change the dose of medicine you are taking. This change may apply to Epclusa or any other medicine you are taking. These medicines can reduce the amount of velpatasvir in your blood. If you are taking any of these medicines, your doctor will either give you another medicine for stomach ulcers, heartburn, or acid reflux or recommend how and when to take it.<\/p>\n\n\n\n The effect of Epclusa during pregnancy is unknown. If you are pregnant, think you may be pregnant, or are planning to have a baby, ask your doctor for advice before taking this medicine.<\/p>\n\n\n\n Epclusa is sometimes used with ribavirin. Ribavirin may cause birth defects. It is therefore very important that you (or your partner) do not become pregnant during this treatment or for a period of time after the treatment. You must read the “Pregnancy” section of the ribavirin package leaflet very carefully. Ask your doctor about an effective method of contraception that is suitable for you and your partner. Breast-feeding<\/strong><\/p>\n\n\n\n Do not breast-feed during treatment with Epclusa. <\/strong>It is not known whether sofosbuvir or velpatasvir, the two active substances in Epclusa, pass into breast milk.<\/p>\n\n\n\n Epclusa should not affect your ability to drive or use any tools or machines. Always take this medicine exactly as your doctor has told you. Ask your doctor or pharmacist if you are unsure. Recommended dose<\/strong><\/p>\n\n\n\n The recommended dose of Epclusa in adults <\/strong>is one 400 mg \/ 100 mg tablet once daily for 12 weeks. The recommended dose of Epclusa in <\/strong>patients aged 6 years to less than 18 years, weighing at least 17 kg, is by weight. Take Epclusa exactly as your doctor has told you.<\/strong> Swallow the tablet (s) whole\/whole with or without food. Do not chew, crush or split the tablet as it has a very bitter taste. If you are taking an antacid,<\/strong> take it at least 4 hours before or at least 4 hours after Epclusa. If you take a proton pump inhibitor,<\/strong> take Epclusa with food 4 hours before proton pump inhibitors are taken. If you vomit after taking Epclusa<\/strong>, it may affect the amount of Epclusa in your blood. This may mean that Epclusa does not work as well.<\/p>\n\n\n\n If you accidentally take more than the recommended dose, contact your doctor, hospital, or Poison Information Center immediately for advice. Bring the jar of tablets with you so that you can easily describe what you have taken. You mustn’t miss a dose of this medicine.<\/p>\n\n\n\n If you miss a dose, calculate how long it has been since you last took Epclusa:<\/p>\n\n\n\n Do not stop taking this medicine unless your doctor tells you to. You must complete the entire course of treatment to give the medicine the best conditions to treat an infection with the hepatitis C virus. If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n Like all medicines, this medicine can cause side effects, although not everybody gets them. Common side effects are<\/strong><\/p>\n\n\n\n (may affect up to 1 in 10 users)<\/em><\/p>\n\n\n\n Uncommon side effects are<\/strong><\/p>\n\n\n\n (may affect up to 1 in 100 people)<\/em><\/p>\n\n\n\n Other effects that can be seen with sofosbuvir treatment:<\/strong><\/p>\n\n\n\n The frequency of the following side effects is unknown (frequency cannot be estimated from the available data).<\/p>\n\n\n\n \u2192 If you get any side effects, talk to your doctor.<\/strong> Keep this medicine out of the sight and reach of children. Do not use this medicine after the expiry date which is stated on the can and carton after \u201cEXP\u201d. The expiration date is the last day of the specified month. No special storage instructions. Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.<\/p>\n\n\n\n Epclusa 400 mg \/ 100 mg film-coated tablets are pink, diamond-shaped tablets, debossed with \u201cGSI\u201d on one side and \u201c7916\u201d on the other side. The tablet is 20 mm long and 10 mm wide. Epclusa 200 mg \/ 50 mg film-coated tablets are pink, oval tablets, debossed with \u201cGSI\u201d on one side and \u201cS \/ V\u201d on the other side. The tablet is 14 mm long and 7 mm wide. The following pack sizes are available for both 400 mg \/ 100 mg and 200 mg \/ 50 mg film-coated tablets:<\/p>\n\n\n\n Gilead Sciences Ireland UC<\/p>\n\n\n\n Carrigtohill<\/p>\n\n\n\n County Cork, T45 DP77<\/p>\n\n\n\n Ireland Manufacturer<\/strong><\/p>\n\n\n\n Gilead Sciences Ireland UC<\/p>\n\n\n\n IDA Business & Technology Park<\/p>\n\n\n\n Carrigtohill<\/p>\n\n\n\n County Cork<\/p>\n\n\n\n Ireland Epclusa is a medicine that contains the active substances sofosbuvir and velpatasvir in a single tablet. It is given to treat a chronic (long-term) viral infection in the liver called hepatitis C, in patients aged 6 years and older, and weighing at least 17 kg.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2205,2200],"tags":[4080,4082,2213,4083,4085,2211,4086,4088,4081,4084,4087],"class_list":["post-8215","post","type-post","status-publish","format-standard","hentry","category-e","category-medicines","tag-epclusa","tag-epclusa-side-effects","tag-medicines","tag-sofosbuvir","tag-sofosbuvir-side-effects","tag-tablets","tag-velpatasvir","tag-velpatasvir-side-effects","tag-what-is-epclusa","tag-what-is-sofosbuvir","tag-what-is-velpatasvir"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8215","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=8215"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8215\/revisions"}],"predecessor-version":[{"id":10486,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8215\/revisions\/10486"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=8215"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=8215"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=8215"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}Warnings and cautions<\/h2>\n\n\n\n
Children and young people<\/h2>\n\n\n\n
Other medicines and Epclusa<\/h2>\n\n\n\n
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<\/p>\n\n\n\nPregnancy and contraception<\/h2>\n\n\n\n
<\/p>\n\n\n\nDriving and using machines<\/h2>\n\n\n\n
<\/p>\n\n\n\n3. How to take Epclusa<\/h2>\n\n\n\n
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<\/p>\n\n\n\nIf you take more Epclusa then you should<\/h2>\n\n\n\n
<\/p>\n\n\n\nIf you forget to take Epclusa<\/h2>\n\n\n\n
Do not stop taking Epclusa<\/h2>\n\n\n\n
<\/p>\n\n\n\n4. Possible side effects<\/h2>\n\n\n\n
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<\/p>\n\n\n\n5. How to store Epclusa<\/h2>\n\n\n\n
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<\/p>\n\n\n\n6. Contents of the packaging and other information<\/h2>\n\n\n\n
Content declaration<\/h2>\n\n\n\n
Film coating: Polyvinyl alcohol, titanium dioxide, polyethylene glycol, talc, red iron oxide.
<\/li><\/ul>\n\n\n\nWhat the medicine looks like and the contents of the pack<\/h2>\n\n\n\n
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<\/p>\n\n\n\nMarketing Authorisation Holder<\/h2>\n\n\n\n
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