Breast-feeding<\/strong><\/p>\n\n\n\nTell your doctor if you are breast-feeding or planning to start breast-feeding. Enalapril Comp Stada is not recommended for breastfeeding mothers.<\/p>\n\n\n\n
Driving and using machines<\/h2>\n\n\n\n
Some side effects (see section 4 below) may affect your ability to drive or use machines, especially at the beginning of treatment or when the dose is increased. Some patients may develop fatigue and dizziness during treatment. If you notice any of these symptoms, do not drive or use machines.
<\/p>\n\n\n\n
You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires increased attention. One of the factors that can affect your ability in these respects is the use of drugs due to. their effects and\/or side effects. Descriptions of these effects and side effects can be found in other sections. Read all the information in this leaflet for guidance. If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n
Enalapril Comp STADA contains lactose and sodium<\/h2>\n\n\n\n
If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.
<\/p>\n\n\n\n
This medicine contains less than 1 mmol (23 mg) sodium per tablet, ie essentially ‘sodium-free’. essentially “sodium-free”.
<\/p>\n\n\n\n
How to use Enalapril Comp STADA<\/h2>\n\n\n\n
Always take this medicine exactly as your doctor has told you. Ask your doctor or pharmacist if you are unsure.
<\/p>\n\n\n\n
This medicine can be used to replace treatment with enalapril and hydrochlorothiazide taken as separate tablets.
<\/p>\n\n\n\n
Dosage<\/strong><\/p>\n\n\n\nYour doctor will decide how much Enalapril Comp Stada to take. Depending on how your blood pressure is affected, your dose may need to be increased or decreased after starting treatment.
<\/p>\n\n\n\n
Adults<\/strong><\/em><\/p>\n\n\n\nThe usual dose is 1 tablet daily.
<\/p>\n\n\n\n
If you have kidney disease, your doctor will check your dose carefully. The lowest dose of Enalapril Comp Stada will be given and your doctor will check how your kidneys are working.<\/p>\n\n\n\n
Your doctor will not prescribe Enalapril Comp Stada if you have severe kidney disease (see section 2. \u201cDo not take Enalapril Comp Stada\u201d).
<\/p>\n\n\n\n
If you are taking another diuretic for the treatment of Enalapril Comp Stada, your doctor will ask you to stop taking this medicine 2-3 days before starting treatment with Enalapril Comp Stada.
<\/p>\n\n\n\n
Elderly patients<\/em><\/p>\n\n\n\nThe efficacy of enalapril and hydrochlorothiazide treatment has been shown in clinical trials to be as good in the elderly as in younger patients. The elderly also tolerate treatment with Enalapril Comp Stada just as well. Renal function usually deteriorates with age, with such conditions a starting dose of half a tablet daily is recommended.<\/p>\n\n\n\n
Use for children and adolescents<\/h2>\n\n\n\n
The safety and efficacy of Enalapril Comp Stada in children have not been established and therefore the drug should not be used in children.<\/p>\n\n\n\n
If you use more Enalapril Comp STADA then you should <\/h2>\n\n\n\n
If you have ingested too much medicine or if e.g. a child ingested the medicine by mistake, contact a doctor, hospital, or the Poison Information Center for risk assessment and advice. Remember to bring the pack, this leaflet, and any remaining tablets. If you have taken too many tablets, you may have severe hypotension (low blood pressure ) and fall asleep (low level of consciousness, but not unconsciousness), as well as other serious disorders (see section 4. “Possible side effects”).<\/p>\n\n\n\n
If you forget to use Enalapril Comp STADA<\/h2>\n\n\n\n
If you forget to take a dose, take the next dose as usual and then continue as scheduled. Do not take a double dose (or larger dose ) to make up for the forgotten dose (or dose ). If you are not sure, talk to your pharmacist or doctor.<\/p>\n\n\n\n
If you stop using Enalapril Comp STADA<\/h2>\n\n\n\n
Do not stop taking Enalapril Comp Stada without first talking to your doctor.
<\/p>\n\n\n\n
If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n
4. Possible side effects<\/h2>\n\n\n\n
Like all medicines, this medicine can cause side effects, although not everybody gets them.
<\/p>\n\n\n\n
- Stop taking Enalapril Comp Stada and contact your doctor immediately<\/strong> if you experience symptoms that indicate angioedema during treatment, such as:
- swelling of the face, tongue, or throat<\/li>
- difficulty swallowing<\/li>
- hives and difficulty breathing.<\/li><\/ul><\/li>
- Enalapril Comp Stada can cause a decrease in different types of white blood cells ( agranulocytosis ) or other blood cells that help defend the body against bacteria ( neutropenia ). This can reduce your resistance to infection. If you get an infection with symptoms such as fever and severe deterioration of the general condition or fever with symptoms of infection such as sore throat\/pharynx\/mouth or urination problems, you should see a doctor as soon as possible so that a lack of white blood cells ( agranulocytosis) can be ruled out through blood tests.). It is important that you then inform if you are taking Enalapril Comp Stada.<\/li><\/ul>\n\n\n\n
Enalapril Comp Stada contains a combination of two active substances, enalapril and hydrochlorothiazide . Thus, any possible side effect may be due to either the active substance enalapril or the active substance hydrochlorothiazide.
<\/p>\n\n\n\n
Very common (may affect more than 1 user in 10):<\/strong><\/p>\n\n\n\n- dizziness<\/li>
- dimsyn<\/li>
- cough<\/li>
- nausea<\/li>
- impotence.<\/li><\/ul>\n\n\n\n
Common (may affect up to 1 in 10 people):<\/strong><\/p>\n\n\n\n- changes in blood values: increase\/decrease in potassium content (hyperkalemia\/hypokalaemia) or creatinine, increase in cholesterol and triglyceride levels (fatty acids), increase in uric acid level in the blood<\/li>
- fainting ( syncope )<\/li>
- fatigue<\/li>
- Depression<\/li>
- headache<\/li>
- taste disorders<\/li>
- low blood pressure ( hypotension ) including a drop in blood pressure, which occurs when getting up quickly, with symptoms such as dizziness or fainting ( orthostatic hypotension )<\/li>
- irregular heartbeat or fast heartbeat ( tachycardia )<\/li>
- chest pain due to anemia and thus lack of oxygen supply to the heart muscle ( angina pectoris )<\/li>
- shortness of breath<\/li>
- diarrhea<\/li>
- abdominal pain<\/li>
- rash<\/li>
- hypersensitivity reactions ( allergy ) and angioedema<\/li>
- muscle cramps<\/li>
- chest pain.<\/li><\/ul>\n\n\n\n
Uncommon (may affect up to 1 in 100 people):<\/strong><\/p>\n\n\n\n- changes in blood values: anemia (aplastic and hemolytic anemia )<\/li>
- low levels of sodium ( hyponatremia ) or sugar (hypoglycemia) and magnesium (hypomagnesemia), elevated urea content<\/li>
- swollen joints ( gout )<\/li>
- confusion, drowsiness ( somnolence ), drowsiness, difficulty falling asleep ( insomnia ), nervousness<\/li>
- an ant crawls ( paresthesia )<\/li>
- vertigo ( vertigo )<\/li>
- decreased sexual desire<\/li>
- ringing in the ears ( tinnitus )<\/li>
- flushing \/ hot flashes<\/li>
- palpitation<\/li>
- severe drop in blood pressure that can lead to heart attack and\/or stroke<\/li>
- runny nose ( rhinorrhea )<\/li>
- sore throat and hoarseness<\/li>
- asthma\/spasm of the trachea (feeling of tightness in the chest that makes it difficult to breathe and hissing)<\/li>
- impaired intestinal motility ( ileus )<\/li>
- inflammation of the pancreas ( pancreatitis )<\/li>
- vomiting and\/or indigestion ( dyspepsia )<\/li>
- constipation<\/li>
- decreased appetite ( anorexia )<\/li>
- gastritis and\/or stomach ulcers<\/li>
- dry mouth<\/li>
- weather stresses ( flatulence )<\/li>
- profuse sweating (diaphoresis)<\/li>
- itching ( pruritus ) or hives ( urticaria )<\/li>
- hair loss ( alopecia )<\/li>
- joint pain<\/li>
- renal impairment or renal failure<\/li>
- egg whites in the urine ( proteinuria )<\/li>
- impotence<\/li>
- feeling sick<\/li>
- muscle twitching associated with fever.<\/li><\/ul>\n\n\n\n
Rare (may affect up to 1 in 1,000 people):<\/strong><\/p>\n\n\n\n- decreased number of certain white blood cells ( neutropenia, leukopenia, and agranulocytosis ), hemoglobin, total red blood cell volume (low hematocrit ), platelets ( thrombocytopenia ), or all different types of blood cells (pancytopenia)<\/li>
- Bone marrow depression ( bone marrow does not produce enough blood cells )<\/li>
- swollen lymph nodes ( lymphadenopathy )<\/li>
- diseases in which the body’s immune system can cause allergic reactions against the body’s own tissue s<\/li>
- elevated blood glucose levels<\/li>
- nightmares and\/or difficulty sleeping<\/li>
- impaired mobility (paresis)<\/li>
- cold hands and feet (Raynaud’s syndrome)<\/li>
- changes visible on X-ray examination of lungs ( pulmonary infiltrates)<\/li>
- allergy ( hypersensitivity reactions ) in the lungs (allergic alveolitis) or lung disease ( eosinophilic pneumonia )<\/li>
- rhinitis ( inflammation of the nose)<\/li>
- severe lung problems (including pneumonia and fluid in the lungs)<\/li>
- inflammation of the oral mucosa ( stomatitis ) or blisters in the mouth<\/li>
- inflammation of the tongue ( glossitis )<\/li>
- abnormal liver function, liver damage ( hepatic necrosis )<\/li>
- elevated liver enzymes (seen by blood tests) or bilirubin in the blood<\/li>
- liver disease (hepatitis; possibly with jaundice ie yellowing of the skin)<\/li>
- increased excretion of bile by the liver (including jaundice)<\/li>
- inflammation of the gallbladder (especially in patients with gallstones )<\/li>
- severe changes in the skin with blisters, redness, and scaling including erythema multiforme, Stevens-Johnson syndrome, exfoliative dermatitis, toxic epidermal necrolysis purpura, cutaneous lupus erythematosus (an immune disease that causes inflammation of the skin), pemphigus and erythroderma (skin redness)<\/li>
- decreased urinary excretion ( oliguria )<\/li>
- interstitial nephritis (a kidney disease)<\/li>
- breast augmentation in men ( gynecomastia )<\/li>
- a group of symptoms that includes any or all of the following: fever, inflammation of body cavities such as chest and abdomen (serositis), inflammation of blood vessels ( vasculitis ), muscle pain or inflammation of the muscles, joint pain, or inflammation of joints, altered blood counts, increased white blood cell count ( eosinophilia, leukocytosis ), skin rash, hypersensitivity to light ( photosensitivity ) and other skin conditions.<\/li><\/ul>\n\n\n\n
Very rare (may affect up to 1 in 10,000 people):<\/strong><\/p>\n\n\n\n- swelling of the intestinal walls (intestinal angioedema )<\/li>
- elevated calcium levels in the blood.<\/li><\/ul>\n\n\n\n
Has been reported (occurs in the unknown number of users):<\/strong><\/p>\n\n\n\n- increased secretion of a hormone ( antidiuretic hormone ) from tissues that do not normally secrete the hormone (may cause headache, nausea, and vomiting)<\/li>
- inflammation of the salivary glands (sialoadenitis)<\/li>
- inflammation of the blood vessels ( necrotizing, vasculitis, cutaneous vasculitis )<\/li>
- anaphylactic (severe allergic \/ hypersensitivity) reactions<\/li>
- restlessness, dizziness<\/li>
- yellow vision<\/li>
- impaired vision or pain in the eyes due to high pressure (possible signs of fluid accumulation in the eye (between the choroid and retina) or acute narrow-angle glaucoma )<\/li>
- sugar in the urine ( glucosuria )<\/li>
- skin and lip cancer (Non- melanoma skin cancer).<\/li><\/ul>\n\n\n\n
5. How to store Enalapril Comp STADA<\/h2>\n\n\n\n
Keep this medicine out of the sight and reach of children.
<\/p>\n\n\n\n
Do not use this medicine after the expiry date which is stated on the carton after EXP. The expiration date is the last day of the specified month.
<\/p>\n\n\n\n
Store in the original package. Do not store above 25 \u00b0 C.
<\/p>\n\n\n\n
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.<\/p>\n\n\n\n
6. Contents of the packaging and other information<\/h2>\n\n\n\nContent declaration<\/h2>\n\n\n\n
The active substances are enalapril and hydrochlorothiazide.
<\/p>\n\n\n\n
- The active substances are enalapril maleate 20 mg and hydrochlorothiazide 6 mg.<\/li>
- The other ingredients are croscarmellose sodium, lactose monohydrate, magnesium stearate, pregelatinized maize starch, sodium bicarbonate, and the dye indigo carmine (E132).<\/li><\/ul>\n\n\n\n
What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n
Light blue, round, uncoated, biconvex tablets.
<\/p>\n\n\n\n
Enalapril Comp Stada is supplied as blister packs (aluminum \/ laminated)<\/p>\n\n\n\n
OPA \/ Al \/ PVC \/ Al): 10, 14, 20, 28, 30, 40, 50, 56, 60, 70, 80, 90, 98, 100, 112, 200, 250, 500 and 1000 tablets.<\/p>\n\n\n\n
PP container with desiccant: 100, 200, 250, 500 or 1000 tablets.
<\/p>\n\n\n\n
Not all pack sizes may be marketed.<\/p>\n\n\n\n
Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n
STADA Arzneimittel AG<\/p>\n\n\n\n
Stadastrasse 2-18<\/p>\n\n\n\n
D-61118 Bad Vilbel<\/p>\n\n\n\n
Germany
<\/p>\n\n\n\n
Other manufacturers<\/strong><\/p>\n\n\n\nActavis Ltd.<\/p>\n\n\n\n
Reykjavikurvegur 76-78<\/p>\n\n\n\n
220 Hafnafj\u00f6r\u00f0ur<\/p>\n\n\n\n
Iceland
<\/p>\n\n\n\n
Balkanpharma Dupnitsa AD<\/p>\n\n\n\n
3 Samokovsko Shose Str.<\/p>\n\n\n\n
Dupnitsa 2600<\/p>\n\n\n\n
Bulgaria
<\/p>\n\n\n\n
Local representative<\/strong><\/p>\n\n\n\nSTADA Nordic ApS<\/p>\n\n\n\n
Marielundvej 46 A<\/p>\n\n\n\n
2730 Herlev<\/p>\n\n\n\n
Denmark
<\/p>\n","protected":false},"excerpt":{"rendered":"
Enalapril Comp Stada is used for treating high blood pressure ( essential hypertension ). It contains a combination of two active substances, enalapril, and hydrochlorothiazide.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2205,2200],"tags":[4306,4308,4309,4310,4312,4313,3664,2213,2211,4307,4311],"class_list":["post-8105","post","type-post","status-publish","format-standard","hentry","category-e","category-medicines","tag-enalapril-and-hydrochlorothiazide","tag-enalapril-and-hydrochlorothiazide-side-effects","tag-enalapril-and-hydrochlorothiazide-tablet","tag-enalapril-comp-stada","tag-enalapril-comp-stada-side-effects","tag-enalapril-comp-stada-tablet","tag-hydrochlorothiazide","tag-medicines","tag-tablets","tag-what-is-enalapril-and-hydrochlorothiazide","tag-what-is-enalapril-comp-stada"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8105","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=8105"}],"version-history":[{"count":3,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8105\/revisions"}],"predecessor-version":[{"id":10550,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8105\/revisions\/10550"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=8105"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=8105"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=8105"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}