lamivudine<\/a>, or adefovir dipivoxil.
<\/p>\n\n\n\nTaking Emtricitabine \/ Tenofovir disoproxil Stop using other <\/strong> medicines that may damage your kidneys<\/strong>: it is especially important to tell your doctor if you are taking<\/p>\n\n\n\n- some such drugs, including<\/li>
- aminoglycoside is (against a bacterial infection )<\/li>
- amphotericin B (against fungal infection)<\/li>
- foscarnet (against a viral infection)<\/li>
- ganciclovir (for virus infection)<\/li>
- pentamidine (against infection )<\/li>
- vancomycin (against a bacterial infection )<\/li>
- interleukin -2 (for the treatment of cancer)<\/li>
- cidofovir (for virus infection)<\/li>
- non-steroidal anti-inflammatory drugs ( NSAIDs, to relieve skeletal or muscle pain).<\/li><\/ul>\n\n\n\n
If you are taking other antiviral medicines, called protease inhibitors, for the treatment of HIV, your doctor may prescribe blood tests to closely monitor your kidney function.
<\/p>\n\n\n\n
It is also important that you tell your doctor<\/strong> if you are taking ledipasvir\/sofosbuvir to treat hepatitis C infection.
<\/p>\n\n\n\nTaking emtricitabine\/tenofovir disoproxil STADA with other medicines containing didanosine (for the treatment of HIV – infection ):<\/strong> If you take emtricitabine\/tenofovir disoproxil STADA with other antiviral medicines that contain didanosine, blood levels of didanosine increase and CD4 cell counts. Rare cases of pancreatitis and lactic acidosis (excess lactic acid in the blood), in some cases fatal, have been reported during concomitant treatment with drugs containing tenofovir disoproxil and didanosine. Your doctor will carefully consider whether you can be treated with a combination of tenofovir and didanosine.
<\/p>\n\n\n\n\u2192 <\/strong> Tell<\/strong> your doctor<\/strong> if you are taking any of these medicines. Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\nEmtricitabine \/ Tenofovir disoproxil Stada with food, drink, and alcohol<\/h2>\n\n\n\n
Whenever possible, Emtricitabine \/ Tenofovir disoproxil Stada should be taken with food.<\/p>\n\n\n\n
Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n
If you are pregnant or breast-feeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.
<\/p>\n\n\n\n
- Although there are limited clinical data on the use of Emtricitabine \/ Tenofovir disoproxil Stada during pregnancy, it is not usually used unless clearly necessary.<\/li><\/ul>\n\n\n\n
- If you are a woman who may become pregnant during treatment with Emtricitabine \/ Tenofovir disoproxil Stada, you must use an effective method of contraception to avoid pregnancy.<\/li><\/ul>\n\n\n\n
- If you are becoming or planning to become pregnant, you must contact your doctor to discuss the benefits and risks of treatment with Emtricitabine \/ Tenofovir disoproxil Stada for you and your baby.<\/li><\/ul>\n\n\n\n
If you have taken Emtricitabine \/ Tenofovir disoproxil Stada during your pregnancy, your doctor may ask you to have regular blood tests and other diagnostic tests to check your baby’s development. For children with a mother who has taken NRTIs during pregnancy, the benefit of HIV protection outweighs the risk of side effects.<\/p>\n\n\n\n
Do not <\/strong>breast-feed <\/strong>during treatment with <\/strong>Emtricitabine \/ Tenofovir disoproxil Stada. <\/strong>This is because the active substances in this medicine are excreted in human breast milk.
<\/p>\n\n\n\nIf you are an HIV- infected woman, do not breast-feed your baby to avoid transmitting HIV to your baby through breast milk.<\/p>\n\n\n\n
Driving and using machines<\/h2>\n\n\n\n
Emtricitabine \/ Tenofovir disoproxil Stada may cause dizziness. Do not drive<\/strong> or use any tools or machines if you feel dizzy while taking Emtricitabine \/ Tenofovir disoproxil Stada.
<\/p>\n\n\n\nYou are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention. One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or side effects. Descriptions of these effects and side effects can be found in other sections. Read all the information in this leaflet for guidance. If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n
Emtricitabine \/ Tenofovir disoproxil Stada contains lactose and sodium<\/h2>\n\n\n\n
If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.
<\/p>\n\n\n\n
This medicine contains less than 1 mmol sodium (23 mg) per tablet, ie essentially ‘sodium-free’. essentially “sodium-free”.
<\/p>\n\n\n\n
How to use Emtricitabine \/ Tenofovir disoproxil Stada<\/h2>\n\n\n\n- Always take this medicine exactly as your doctor has told you. <\/strong>Ask your doctor or pharmacist if you are unsure.<\/li><\/ul>\n\n\n\n
The recommended dose of emtricitabine\/tenofovir disoproxil Stada for treatment for HIV or to reduce the risk of getting HIV are:<\/strong>
<\/p>\n\n\n\n- Adults:<\/strong> one tablet a day. Whenever possible, Emtricitabine \/ Tenofovir disoproxil Stada should be taken with food.<\/li><\/ul>\n\n\n\n
If you have difficulty swallowing, you can crush the tablet with the tip of a spoon. Then mix the powder with about 100 ml (half a glass) of water, orange juice, or grape juice and drink immediately.
<\/p>\n\n\n\n
- Always take the dose prescribed<\/strong> by your <\/strong>doctor<\/strong> to ensure that the medicine is effective and to reduce the development of resistance to treatment. Do not change the dose unless your doctor tells you to.<\/li><\/ul>\n\n\n\n
- If you are being treated for HIV – infection<\/strong>, your doctor will write out the emtricitabine\/tenofovir disoproxil STADA with other antiretroviral drugs. Read the package leaflets for these medicines for instructions on how to take them.<\/li><\/ul>\n\n\n\n
- If you are taking Emtricitabine \/ Tenofovir disoproxil Stada to reduce the risk of getting HIV,<\/strong> take Emtricitabine \/ Tenofovir disoproxil Stada every day, not just when you think you are at risk of being infected with HIV.<\/li><\/ul>\n\n\n\n
Ask your doctor if you have any questions about how to prevent getting HIV or transmitting HIV to other people.<\/p>\n\n\n\n
If you use more Emtricitabine \/ Tenofovir disoproxil Stada then you should <\/h2>\n\n\n\n
If you have ingested too much medicine or if e.g. a child has ingested the medicine by mistake, contact a doctor, hospital, or the Poison Information Center for risk assessment and advice. Save the jar so you can easily describe what you have taken.<\/p>\n\n\n\n
If you forget to use Emtricitabine \/ Tenofovir disoproxil Stada<\/h2>\n\n\n\n
You mustn’t miss a dose of Emtricitabine \/ Tenofovir disoproxil Stada.
<\/p>\n\n\n\n
- If you notice it within 12 hours<\/strong> from the time you usually take Emtricitabine \/ Tenofovir disoproxil Stada, take the tablet, preferably with food, as soon as possible. Then take the next dose at the usual time.<\/li>
- If you notice it 12 hours or more after<\/strong> the time you usually take Emtricitabine \/ Tenofovir disoproxil Stada, ignore the missed dose. Wait and take the next dose, preferably with food, at the usual time.<\/li><\/ul>\n\n\n\n
If you vomit within less than 1 hour after a dose of <\/strong>Emtricitabine \/ Tenofovir disoproxil Stada,<\/strong> take a new tablet. You do not need to take a new tablet if you vomit more than 1 hour after taking Emtricitabine \/ Tenofovir disoproxil Stada.<\/p>\n\n\n\nIf you stop using Emtricitabine \/ Tenofovir disoproxil Stada<\/h2>\n\n\n\n
Do not stop taking <\/strong>Emtricitabine \/ Tenofovir disoproxil Stada <\/strong>
<\/p>\n\n\n\n- If you take emtricitabine\/tenofovir disoproxil Stada for treatment of HIV – infection <\/strong>if you stop taking the tablets, the effect of the anti- HIV treatment the doctor has recommended is reduced.<\/li><\/ul>\n\n\n\n
- If you are taking Emtricitabine \/ Tenofovir disoproxil Stada to reduce the risk of getting HIV, <\/strong>do not stop taking Emtricitabine \/ Tenofovir disoproxil Stada or miss any dose. If you stop using emtricitabine\/tenofovir disoproxil Stada or miss the dose you, the risk of you getting HIV – infection increase.<\/li><\/ul>\n\n\n\n
\u2192 Do not stop taking <\/strong>Emtricitabine \/ Tenofovir disoproxil Stada without first talking to your doctor.<\/strong>
<\/p>\n\n\n\n- If you have chronic hepatitis B<\/strong>, you mustn’t stop taking Emtricitabine \/ Tenofovir disoproxil Stada without talking to your doctor first. You may need to submit blood samples for several months after stopping treatment. In some patients with advanced liver disease or cirrhosis, discontinuation of treatment is not recommended as this may lead to worsening of hepatitis A, which may be life-threatening.<\/li><\/ul>\n\n\n\n
\u2192 Tell your doctor immediately<\/strong> about any new and unexpected symptoms that occur after stopping treatment, especially symptoms that you usually associate with your hepatitis B infection.
<\/p>\n\n\n\nIf you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n
4. Possible side effects<\/h2>\n\n\n\n
Like all medicines, this medicine can cause side effects, although not everybody gets them.
<\/p>\n\n\n\n
Possible serious side effects:<\/strong><\/p>\n\n\n\n- Lactic acidosis<\/strong> (excess lactic acid in the blood) is a rare but potentially life-threatening side effect. Lactic acidosis occurs more frequently in women, especially if they are overweight, and in people with liver disease. The following may be signs of lactic acidosis:
- deep, rapid breathing<\/li>
- drowsiness<\/li>
- nausea, vomiting<\/li>
- abdominal pain.<\/li><\/ul><\/li><\/ul>\n\n\n\n
\u2192 <\/strong>If you think you may have lactic acidosis, seek medical attention immediately.<\/strong>
<\/p>\n\n\n\n- Any signs of inflammation or infection. <\/strong>In some patients with advanced HIV – infection ( AIDS ) and a history of opportunistic infection, ( the infection that occurs in people with a weak immune system), signs and symptoms of inflammation from previous infections may occur soon after the treatment against HIV begin. It is believed that these symptoms are due to an improvement in the body’s immune system and enable the body to fight infections that may have existed without any visible symptoms.<\/li><\/ul>\n\n\n\n
- Autoimmune disorders,<\/strong> where the immune system attacks healthy body tissue, can also occur after you start taking medicines for the treatment of HIV – infection. Autoimmune disorders can occur many months after starting treatment. Be aware of any symptoms of infection or other symptoms such as:
- muscle weakness<\/li>
- weakness that begins in the hands and feet and moves upwards towards the torso<\/li>
- palpitations, tremors or hyperactivity.<\/li><\/ul><\/li><\/ul>\n\n\n\n
\u2192 If you notice these or any symptoms of inflammation or infection, seek medical attention immediately.<\/strong>
<\/p>\n\n\n\nAny side effects are<\/strong>
<\/p>\n\n\n\nA very common side effect is<\/strong> (can occur in more than 1 in 10):<\/p>\n\n\n\n- diarrhea, vomiting, nausea<\/li>
- dizziness, headache<\/li>
- rash<\/li>
- feeling weak.<\/li><\/ul>\n\n\n\n
Samples can also show:<\/em><\/p>\n\n\n\n- lowering of phosphate levels in the blood<\/li>
- elevated creatine kinase.<\/li><\/ul>\n\n\n\n
Common side effects are<\/strong> (may affect up to 1 in 10):<\/p>\n\n\n\n- pain, abdominal pain<\/li>
- difficulty sleeping, abnormal dreams<\/li>
- indigestion which results in discomfort after meals, feeling of bloating, flatulence<\/li>
- skin rash (including red spots or skin blemishes sometimes with blistering and swelling of the skin) which may be allergic reactions, itching, discoloration of the skin including dark spots on the skin<\/li>
- other allergic reactions, such as wheezing\/wheezing, swelling, or intoxication.<\/li><\/ul>\n\n\n\n
Samples can also show:<\/em><\/p>\n\n\n\n- low white blood cell count (a decrease in white blood cell count may make you more likely to get an infection )<\/li>
- elevated levels of triglycerides (fatty acids) in the blood, increased amount of bile pigments in the blood, or elevated blood sugar<\/li>
- liver and pancreatic disorders.<\/li><\/ul>\n\n\n\n
Less common side effects are<\/strong> (may affect up to 1 in 100):<\/p>\n\n\n\n- abdominal pain (stomach) caused by inflammation of the pancreas<\/li>
- swelling of the face, lips, tongue, or throat<\/li>
- anemia (low red blood cell count )<\/li>
- muscle breakdown, muscle pain, or muscle weakness that can occur due to damage to kidney tubules.<\/li><\/ul>\n\n\n\n
Samples can also show:<\/em><\/p>\n\n\n\n- decreased potassium levels in the blood<\/li>
- elevated creatinine content in the blood<\/li>
- changes in the urine.<\/li><\/ul>\n\n\n\n
Rare side effects are<\/strong> (may affect up to 1 in 1000):<\/p>\n\n\n\n- lactic acidosis (see Possible serious side effects )<\/li>
- fatty liver<\/li>
- yellow skin or yellow eyes, itching, or pain in the abdomen (stomach) caused by inflammation of the liver<\/li>
- kidney inflammation, urinating a lot and feeling thirsty, kidney failure, damage to kidney tubules<\/li>
- impaired bone hardness (which causes skeletal pain and sometimes leads to fractures )<\/li>
- back pain caused by kidney problems.<\/li>
- Damage to kidney tubules can be associated with muscle breakdown, decreased bone hardness (which causes skeletal pain and sometimes leads to fractures ), muscle pain, muscle weakness, and decreased potassium or phosphate levels in the blood.<\/li><\/ul>\n\n\n\n
\u2192 If you notice any of the above side effects or if any of the side effects gets serious<\/strong>, talk to your doctor or pharmacist.
<\/p>\n\n\n\nThe frequency of the following side effects is unknown.<\/p>\n\n\n\n
- Skeletal problem. <\/strong>Some patients taking combination antiretroviral medicines such as Emtricitabine \/ Tenofovir disoproxil Stada may develop a bone disease called osteonecrosis (bone tissue death caused by the lost blood supply to the bone tissue). Some of the many risk factors for developing this disease are long-term use of this type of drug, use of corticosteroids, use of alcohol, very weak immune system, and obesity. Signs of osteonecrosis are:
- joint stiffness<\/li>
- joint pain and pain (especially in the hip joint, knee joint, and shoulder joint)<\/li>
- difficulty moving.<\/li><\/ul><\/li><\/ul>\n\n\n\n
\u2192 Tell your doctor if you notice any of these symptoms.<\/strong>
<\/p>\n\n\n\nDuring treatment for HIV, there may be weight gain and an increase in blood fat and blood glucose levels. This is partly related to improved health and lifestyle and as far as blood fats are concerned, sometimes with the HIV drugs themselves. Your doctor will take samples for this.
<\/p>\n\n\n\n
5. How to store Emtricitabine \/ Tenofovir disoproxil Stada<\/h2>\n\n\n\n
Keep this medicine out of the sight and reach of children.
<\/p>\n\n\n\n
Do not use this medicine after the expiry date which is stated on the can and carton after EXP. The expiration date is the last day of the specified month.
<\/p>\n\n\n\n
Store in the original package. Moisture sensitive. Close the jar tightly.
<\/p>\n\n\n\n
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.<\/p>\n\n\n\n
6. Contents of the packaging and other information<\/h2>\n\n\n\nContent declaration<\/h2>\n\n\n\n
The active substances are <\/strong>emtricitabine<\/em> and tenofovir disoproxil<\/em>.<\/p>\n\n\n\nOne Emtricitabine \/ Tenofovir disoproxil Stada film-coated tablet contains 200 mg emtricitabine and 245 mg tenofovir disoproxil (equivalent to 300.6 mg tenofovir disoproxil succinate).
<\/p>\n\n\n\n
The other ingredients are <\/strong>lactose monohydrate, microcrystalline cellulose (E460), pregelatinized maize starch, croscarmellose sodium, magnesium stearate (E470b), polyvinyl alcohol (E1203), titanium dioxide (E171), macrogol 3350 (E1521b), talc (E15igm) (ind2g).<\/p>\n\n\n\nWhat the medicine looks like and the contents of the pack<\/h2>\n\n\n\n
Emtricitabine \/ Tenofovir disoproxil Stada is a blue capsule-shaped, film-coated tablet that is smooth on both sides. The dimensions of the tablet are 19.3 mm x 8.8 mm \u00b1 5%.
<\/p>\n\n\n\n
Emtricitabine \/ Tenofovir disoproxil Stada is supplied in HDPE bottles of 30 tablets. Each jar contains desiccant (silica gel) which must be present in the jar to protect the tablets. The desiccant (silica gel) is contained in a separate container and should not be swallowed.
<\/p>\n\n\n\n
Pack sizes: 1 x 30 film-coated tablets and 3 x 30 film-coated tablets.
<\/p>\n\n\n\n
Not all pack sizes may be marketed.<\/p>\n\n\n\n
Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n
STADA Arzneimittel AG<\/p>\n\n\n\n
Stadastrasse 2-18<\/p>\n\n\n\n
61118 Bad Vilbel<\/p>\n\n\n\n
Germany
<\/p>\n\n\n\n
Other manufacturers<\/strong><\/p>\n\n\n\nRemedica Ltd<\/p>\n\n\n\n
Aharnon Street, Limassol Industrial Estate, 3056 Limassol<\/p>\n\n\n\n
Cyprus
<\/p>\n\n\n\n
STADA Arzneimittel GmbH<\/p>\n\n\n\n
Muthgasse, 36\/2, 1190 Vienna<\/p>\n\n\n\n
Austria
<\/p>\n\n\n\n
STADA Nordic ApS<\/p>\n\n\n\n
Marielundvej 46A, 2730 Herlev<\/p>\n\n\n\n
Denmark
<\/p>\n\n\n\n
Centrafarm Services BV<\/p>\n\n\n\n
Nieuwe Donk 9, 4879 AC Etten-Leur<\/p>\n\n\n\n
Netherlands
<\/p>\n\n\n\n
Clonmel Healthcare Ltd<\/p>\n\n\n\n
Waterford Road, Clonmel, Co. Tipperary<\/p>\n\n\n\n
Ireland
<\/p>\n\n\n\n
Local representative<\/strong><\/p>\n\n\n\nSTADA Nordic ApS<\/p>\n\n\n\n
Marielundvej 46A<\/p>\n\n\n\n
2730 Herlev<\/p>\n\n\n\n
Denmark
<\/p>\n","protected":false},"excerpt":{"rendered":"
Emtricitabine \/ Tenofovir disoproxil Stada contains two active substances, emtricitabine and tenofovir disoproxil . Both of these active substances are antiretroviral drugs used to treat HIV – infection. Emtricitabine is a nucleoside reverse transcriptase inhibitor and tenofovir is a nucleotide reverse transcriptase inhibitor. However, both are commonly called NRTIs and act by affecting the normal function of an enzyme (reverse transcriptase) that the virus needs for its reproduction (propagation).<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2205,2200],"tags":[3398,3401,3389,4333,4318,4330],"class_list":["post-8097","post","type-post","status-publish","format-standard","hentry","category-e","category-medicines","tag-emtricitabine","tag-emtricitabine-side-effects","tag-tenofovir-disoproxil","tag-tenofovir-disoproxil-stada","tag-what-is-emtricitabine","tag-what-is-tenofovir-disoproxil"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8097","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=8097"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8097\/revisions"}],"predecessor-version":[{"id":10559,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8097\/revisions\/10559"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=8097"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=8097"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=8097"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}