{"id":8083,"date":"2021-03-05T10:32:21","date_gmt":"2021-03-05T10:32:21","guid":{"rendered":"https:\/\/zeepedia.com\/?p=8083"},"modified":"2023-01-06T06:41:59","modified_gmt":"2023-01-06T06:41:59","slug":"empressin","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/empressin\/","title":{"rendered":"Empressin &#8211; Argipressin Uses, Dose, And Side Effects"},"content":{"rendered":"\n<p><strong>Empressin 40 IU \/ 2 mL&nbsp;concentrate for solution for argipressin&nbsp;infusion&nbsp;solution.&nbsp;<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What Empressin Is And What Is Empressin Used For<\/h2>\n\n\n\n<p>This medicine contains argipressin, a synthetic substance corresponding to the natural\u00a0hormone\u00a0et\u00a0vasopressin.\u00a0It regulates the body&#8217;s fluid balance and reduces urine excretion.\u00a0This medicine is used in cases of\u00a0septic\u00a0shock\u00a0when other methods of achieving the desired\u00a0blood pressure, according to the attending physician, have not worked.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2. What You Need To Know Before Using Empressin<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do Not Use <\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>If you are <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/peanut-allergy-and-nut-allergy\/\">hypersensitive<\/a> to argipressin or any of the other ingredients of this (listed in section 6).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings And Cautions<\/h2>\n\n\n\n<p><strong>Special precautions must be taken when using <\/strong>it<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>To raise&nbsp;blood pressure&nbsp;in case of&nbsp;shock&nbsp;after using other blood pressure-raising methods.&nbsp;The administration&nbsp;must carefully control vital parameters, e.g.,&nbsp;heart rate&nbsp;and&nbsp;blood pressure.<\/li><li>If you have cardiovascular disease.<\/li><li>If you have&nbsp;<ul><li>Epilepsy<\/li><li>Migraine<\/li><li>Asthma<\/li><li>Heart failure,&nbsp;or disease where a rapid increase in fluid in the body poses a risk.<\/li><\/ul><\/li><li>If you suffer from&nbsp;chronic&nbsp;nephritis (<a href=\"https:\/\/zeepedia.com\/medical\/diseases\/kidney-inflammation\/\">kidney inflammation<\/a>).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Children And Young People<\/h2>\n\n\n\n<p>The use of this medicine in children and newborns is not normally recommended.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other Medicines And Empressin<\/h2>\n\n\n\n<p>It should be used with caution in combination with <\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Carbamazepine<\/li><li>Chloropropamide<\/li><li>Clofibrate,\u00a0urea<\/li><li>Fludrocortisone<\/li><li>Tricyclic antidepressants,\u00a0as these agents, may potentiate the effect of it. This medicine should be given with caution along with demeclocycline,\u00a0norepinephrine lithium,\u00a0heparin,\u00a0or <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/alcohol-and-drugs-risk-use-harmful-use-and-addiction\/\">alcohol<\/a>, as these substances may reduce their effects.\u00a0Concomitant use of this medicine and blood pressure medication may increase or decrease the pressure induced by Empressin.<\/li><\/ul>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Empress With Food And Drink<\/h2>\n\n\n\n<p>Empress must not be used in combination with alcohol.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>This medicine can cause uterine contractions and increased pressure in the uterus during pregnancy and may reduce blood flow in the uterus.\u00a0This medicine should not be used during pregnancy unless necessary.<\/p>\n\n\n\n<p>It is not known whether this medicine is excreted in human milk.<br>The use of Empressin during pregnancy and lactation is not recommended.\u00a0Ask your doctor or pharmacist for advice before taking any medicine during pregnancy or breastfeeding.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving And Using Machines<\/h2>\n\n\n\n<p>No studies on the effects on the ability to drive and use machines have been performed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Important Information About Some Of The Ingredients Of Empressin<\/h2>\n\n\n\n<p>This medicine contains less than 1 mmol&nbsp;sodium&nbsp;(23 mg) per&nbsp;dose, i.e., essentially &#8216;sodium-free.&#8217;<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. How To Use Empressin<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>This will be given to you by a doctor.<\/li><li><strong>Empressin dosage <\/strong>should only be used as an adjunct to other treatments.\u00a0Initially, 0.01 IU per minute is given as an\u00a0infusion.\u00a0This\u00a0dose\u00a0can be increased every 15-20 minutes by up to 0.03 IU per minute.\u00a0Higher\u00a0doses\u00a0should only be used in an emergency.<\/li><li><strong>Empressin infusion<\/strong> is long-term\u00a0and must be diluted with physiological saline.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Use For Children And Adolescents<\/h2>\n\n\n\n<p>Empressin has been used to treat certain shock conditions in infants, toddlers, and children in intensive care and during surgery.&nbsp;However, using Empressin in children and newborns is generally not recommended.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If You Use More Empressin Than You Should<\/h2>\n\n\n\n<p>This medicine will be given to you by a doctor.&nbsp;Talk to your doctor immediately if you think you have been given too high a dose of this medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop using Empressin<\/h2>\n\n\n\n<p>Discontinuation of this drug must be gradual, meaning treatment should not be stopped abruptly.&nbsp;If you think that the use of the medicine has been stopped too soon, talk to your doctor immediately.<\/p>\n\n\n\n<p>Ask your doctor or nurse if you have further questions about using this product.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible Side Effects Of Empressin<\/h2>\n\n\n\n<p>This medicine can cause side effects like all medicines, although not everybody gets them.<\/p>\n\n\n\n<p>Common side effects of empressin (may affect up to 1 in 10 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Abnormal heartbeat<\/li><li>Pressure over the chest<\/li><li>Circulatory disorders in the heart muscle, the intestines, or fingertips<\/li><li>Peripheral&nbsp;narrowing of blood vessels<\/li><li>Necrosis<\/li><li>Stomach cramps<\/li><li>Pallor around the mouth<\/li><li>Tissue death in the skin<\/li><\/ul>\n\n\n\n<p>Uncommon (may affect up to 1 in 100 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Low levels of&nbsp;sodium&nbsp;in the blood<\/li><li>Shaking<\/li><li>Dizziness<\/li><li>Headache<\/li><li>Decreased circulating blood volume<\/li><li>Life-threatening change in heart rhythm<\/li><li>Cardiac arrest<\/li><li>Respiratory distress caused by the narrowing of the airways<\/li><li>Nausea<\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/stomach-disease-diarrhea-and-vomiting\/\">Vomiting<\/a><\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/flatulence\/\">Gas in the stomach<\/a><\/li><li>Tissue death in the intestine<\/li><li>Sweating<\/li><li>Rash<\/li><li>Changes in certain laboratory values \u200b\u200bin the blood<\/li><\/ul>\n\n\n\n<p>Rare (may affect up to 1 in 1,000 people)<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Severe and life-threatening&nbsp;allergic reaction<\/li><\/ul>\n\n\n\n<p>Has been reported (occurs in an unknown number of people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Water poisoning<\/li><li>A strong dilution of the salinity in the body can be life-threatening<\/li><li>Diabetes insipidus&nbsp;is a condition that, among other things<\/li><li>This leads to large amounts of urine and constant thirst after treatment interruption.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">5. How To Store Empressin<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Keep this medicine out of sight and reach of children.<\/li><li>Store in a refrigerator (2 \u00b0 C &#8211; 8 \u00b0 C).<\/li><li>Do not use this medicine after the expiry date stated on the label and carton.&nbsp;The expiration date is the last day of the specified month.<\/li><li>After opening, the drug should be diluted and used immediately.<\/li><\/ul>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines that are no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents Of The Packaging And Other Information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content Declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is argipressin.<\/li><li>1&nbsp;ampoule&nbsp;with 2 ml concentrate for&nbsp;solution&nbsp;for&nbsp;infusion&nbsp;contains argipressin acetate equivalent to 40 IU argipressin (equivalent to 133 micrograms).<\/li><li>The other ingredients are sodium chloride, concentrated acetic acid to adjust the&nbsp;pH, and water for injections.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What The Medicine Looks Like And The Contents Of The Pack<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Empressin is a clear and colourless concentrate solution&nbsp;for&nbsp;infusion.<\/li><li>Each pack contains 5 or 10&nbsp;ampoules.<\/li><li>Not all pack sizes may be marketed.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder And Manufacturer<\/h2>\n\n\n\n<p><strong>Marketing Authorisation Holder<\/strong><\/p>\n\n\n\n<p>Orpha-Devel Handels und Vertriebs GmbH<\/p>\n\n\n\n<p>Wintergasse 85 \/ 1B<\/p>\n\n\n\n<p>3002 Purkersdorf<\/p>\n\n\n\n<p>Austria<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Amomed Pharma GmbH<\/p>\n\n\n\n<p>Storchengasse 1<\/p>\n\n\n\n<p>1150 Vienna<\/p>\n\n\n\n<p>Austria<br><\/p>\n\n\n\n<p><strong>This medicinal product is authorized under the European Economic Area under the following names:<\/strong><\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td>Austria<\/td><td>Empesin 40 IU \/ 2 ml concentrate for the preparation of an infusion solution<\/td><\/tr><tr><td>Belgium<\/td><td>Reverage 40 IU \/ 2 ml concentrate for solution for infusion<\/td><\/tr><tr><td>Bulgaria<\/td><td>\u0415\u043c\u043f\u0440\u0435\u0441\u0438\u043d 40 IU \/ 2ml \u041a\u043e\u043d\u0446\u0435\u043d\u0442\u0440\u0430\u0442 \u0437\u0430 \u0438\u043d\u0444\u0443\u0437\u0438\u043e\u043d\u0435\u043d \u0440\u0430\u0437\u0442\u0432\u043e\u0440 Empressin 40 IU \/ 2ml concentrate for&nbsp;infusion&nbsp;solution<\/td><\/tr><tr><td>Czech Republic<\/td><td>Embesin<\/td><\/tr><tr><td>Germany<\/td><td>Empress 40 IU \/ 2 ml concentrate on preparing an infusion solution.<\/td><\/tr><tr><td>Denmark<\/td><td>Empress<\/td><\/tr><tr><td>Estonia<\/td><td>Empesin<\/td><\/tr><tr><td>Greece<\/td><td>Empressin 40 IU \/ 2 ml Dilated glass with a double-edged glass<\/td><\/tr><tr><td>Spain<\/td><td>Empressin 40 IU \/ 2 ml concentrate for solution for perfusion<\/td><\/tr><tr><td>Finland<\/td><td>Empressin 40 IU \/ 2 ml infusion concentrate, liuosta varten<\/td><\/tr><tr><td>France<\/td><td>Reverpleg 40 UI \/ 2ml solution for dilution for&nbsp;perfusion<\/td><\/tr><tr><td>Hungary<\/td><td>Embesyn 40 NE \/ 2ml concentrate for infusion solution<\/td><\/tr><tr><td>Croatia<\/td><td>Empressin 40 IU \/ 2 ml concentrate for otopinu for infusion<\/td><\/tr><tr><td>Ireland<\/td><td>Embesin<\/td><\/tr><tr><td>Italy<\/td><td>Empressin 40 IU \/ 2 ml concentrate per solution for infusion<\/td><\/tr><tr><td>Lithuania<\/td><td>Empesin<\/td><\/tr><tr><td>Luxembourg<\/td><td>Empressin 40 IU \/ 2 ml dilution solution for&nbsp;perfusion<\/td><\/tr><tr><td>Latvia<\/td><td>Empesin 40 SV \/ 2 ml concentrated infusion solution<\/td><\/tr><tr><td>Netherlands<\/td><td>Empressin 40 IU \/ 2ml, concentrate for solution for infusion<\/td><\/tr><tr><td>Norway<\/td><td>Empress<\/td><\/tr><tr><td>Poland<\/td><td>Empesin<\/td><\/tr><tr><td>Portugal<\/td><td>Empressin 40 UI \/ 2ml concentrated for perfusion solution<\/td><\/tr><tr><td>Romania<\/td><td>Reverpleg<\/td><\/tr><tr><td>Slovenia<\/td><td>Empesin 40 IU \/ 2 ml concentrate for raztopino for infusion<\/td><\/tr><tr><td>Slovakia<\/td><td>Embesin 40 IU \/ 2 ml infusion concentrate<\/td><\/tr><\/tbody><\/table><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>Empressin\u00ae is used to treat catecholamine refractory hypotension following septic shock in patients older than 18.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2205,2200],"tags":[4370,4373,4372,4374,4378,4377,4376,2213,4371,4375],"class_list":["post-8083","post","type-post","status-publish","format-standard","hentry","category-e","category-medicines","tag-argipressin","tag-argipressin-infusion","tag-argipressin-side-effects","tag-empressin","tag-empressin-dose","tag-empressin-infusion","tag-empressin-side-effects","tag-medicines","tag-what-is-argipressin","tag-what-is-empressin"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8083","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=8083"}],"version-history":[{"count":53,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8083\/revisions"}],"predecessor-version":[{"id":43711,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8083\/revisions\/43711"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=8083"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=8083"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=8083"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}