{"id":8045,"date":"2021-03-04T08:02:27","date_gmt":"2021-03-04T08:02:27","guid":{"rendered":"https:\/\/zeepedia.com\/?p=8045"},"modified":"2023-02-21T10:43:40","modified_gmt":"2023-02-21T10:43:40","slug":"emgality","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/emgality\/","title":{"rendered":"Emgality &#8211; Galkanezumab Uses, Dose, And Side Effects"},"content":{"rendered":"\n<p><strong>Emgality 120 mg&nbsp;injection, solution in a prefilled&nbsp;pen&nbsp;galkanezumab<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What Emgality Is And What It Is Used For<\/h2>\n\n\n\n<p>This medicine contains galkanezumab, a drug that prevents the activity of a naturally occurring substance in the body called a calcitonin-related&nbsp;peptide&nbsp;(CGRP).&nbsp;People with&nbsp;migraines&nbsp;may have elevated levels of CGRP.<\/p>\n\n\n\n<p>This is used to prevent&nbsp;<a href=\"https:\/\/zeepedia.com\/diseases\/brain-and-nerves\/migraine\/\"><strong>migraine<\/strong><\/a>&nbsp;in adult patients who have at least 4 migraine days per month.<\/p>\n\n\n\n<p>This medicine can reduce your migraine attacks and improve your quality of life.&nbsp;It starts to work after about a week.<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"466\" height=\"177\" src=\"https:\/\/zeepedia.com\/wp-content\/uploads\/2021\/03\/emgality.png\" alt=\"emgality\" class=\"wp-image-45721\" srcset=\"https:\/\/zeepedia.com\/medical\/wp-content\/uploads\/2021\/03\/emgality.png 466w, https:\/\/zeepedia.com\/medical\/wp-content\/uploads\/2021\/03\/emgality-300x114.png 300w\" sizes=\"auto, (max-width: 466px) 100vw, 466px\" \/><\/figure><\/div>\n\n\n<h2 class=\"wp-block-heading\">2. What You Need To Know Before Using Emgality<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do Not Use Emgality<\/h2>\n\n\n\n<p>If you are allergic to galkanezumab or any of the other ingredients of this medicine (see label).<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings And Cautions<\/h2>\n\n\n\n<p>If you have a serious cardiovascular disease, talk to your doctor, pharmacist, or nurse before using it.&nbsp;This medicine has not been studied in patients with severe cardiovascular disease.<\/p>\n\n\n\n<p><strong>Be aware of allergic reactions to emgality<\/strong><\/p>\n\n\n\n<p>There is a risk that can cause <strong><em>emgality allergic reaction<\/em><\/strong>.&nbsp;You must be aware of signs of such reactions while using it.&nbsp;Stop taking doses and contact a doctor or see the nearest emergency department immediately if there are signs of a severe&nbsp;<span style=\"text-decoration: underline;\">allergic reaction to emgality<\/span>.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children And Young People<\/h2>\n\n\n\n<p>This medicine is not recommended for children and adolescents under 18 years of age as it has not been studied in this age group.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other Drugs And Emgality<\/h2>\n\n\n\n<p>Tell your doctor, pharmacist, or nurse if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, Breastfeeding, And Fertility<\/h2>\n\n\n\n<p>If you are a woman and can have children, you are advised to avoid becoming pregnant while being treated with this medicine.<\/p>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor for advice before using this medicine.&nbsp;You should not use it during pregnancy as the effects of this medicine on pregnant women are not known.<\/p>\n\n\n\n<p>If you are breastfeeding or planning to breastfeed, talk to your doctor before using this medicine.&nbsp;You and your doctor should decide if you can breastfeed and use this medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving And Using Machines<\/h2>\n\n\n\n<p>Galkanezumab may have a minor effect on your ability to drive or use machines.&nbsp;Some patients have experienced <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/brain-and-nerves\/dizziness\/\">dizziness<\/a> while using it.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Emgality Contains Excipients<\/h2>\n\n\n\n<p>This medicine contains less than 1 mmol&nbsp;sodium&nbsp;(23 mg) per 120 mg&nbsp;dose, ie&nbsp;essentially &#8216;sodium-free&#8217;.&nbsp;is almost &#8220;sodium-free&#8221;.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. How To Use Emgality<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Always use this medicine exactly as your doctor, pharmacist or nurse has told you.&nbsp;If you are not sure, talk to your doctor, pharmacist, or nurse.<\/li><li>Emgality prefilled&nbsp;injection pen&nbsp;is intended for single use and contains a&nbsp;dose&nbsp;of Emgality (120 mg).<ul><li>The first time you get this injection, your doctor or nurse will inject the contents of 2 pre-filled pens (240 mg in total).<\/li><li>After the first&nbsp;dose, use 1 pre-filled pen (120 mg) a month.<\/li><\/ul><\/li><li>Your doctor will decide how long you should use it.<\/li><li>This medicine is given as an&nbsp;injection&nbsp;under the skin (&nbsp;subcutaneous&nbsp;injection&nbsp;).&nbsp;You and your doctor or nurse should decide if you can give yourself the&nbsp;injections&nbsp;with Emgality.<\/li><li>You mustn&#8217;t try to give the&nbsp;injections&nbsp;yourself until the doctor or nurse has shown you how to do it.&nbsp;A caregiver can also give you an Emgality&nbsp;injection after you have received training.<\/li><li>The pen must not be shaken.<\/li><li>Carefully read the instructions for use of the pen before using it.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">If You Use More Emgality Than You Should &nbsp;<\/h2>\n\n\n\n<p>If you have injected too much medicine, e.g.&nbsp;If you have&nbsp;injected two&nbsp;doses&nbsp;of 240 mg&nbsp;after the first&nbsp;dose&nbsp;during the same month, or if someone else has accidentally used this medicine, contact your doctor immediately.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If You Forget To Use Emgality<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Do not take a double&nbsp;dose&nbsp;to make up for a forgotten&nbsp;injection.<\/li><li>If you forget to inject one&nbsp;dose of&nbsp;Emgality, inject the missed&nbsp;dose&nbsp;as soon as possible and then continue with the next&nbsp;dose&nbsp;one month after that date.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">If You Stop Using Emgality<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Do not stop using Emgality without talking to your doctor first.<\/li><\/ul>\n\n\n\n<p>If you have any further questions about the use of this product, ask your doctor, pharmacist, or nurse.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible Emgality Side Effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects, although not everybody gets them.<\/p>\n\n\n\n<p><strong>Serious&nbsp;side effects&nbsp;of emgality are<\/strong>&nbsp;<\/p>\n\n\n\n<p><em>Allergic reaction to emgality <\/em>is usually mild to moderate (such as rash or&nbsp;itching&nbsp;).&nbsp;Severe <strong>emgality allergic reactions <\/strong>are rare (may affect up to 1 in 1,000 people) and may include:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/respiratory-difficulties-in-children\/\">Difficulty breathing<\/a> or swallowing<\/li><li>Low&nbsp;blood pressure, which can cause dizziness or unsteadiness<\/li><li>Swelling of the neck, face, mouth, lips, tongue, or throat can develop rapidly<\/li><li>Severe&nbsp;itching&nbsp;of the skin, with a red rash or raised lumps.<\/li><\/ul>\n\n\n\n<p>Tell your doctor or seek&nbsp;emergency&nbsp;care&nbsp;if you get any of these signs.<\/p>\n\n\n\n<p><strong>Other&nbsp;emgality side effects&nbsp;that have been reported:<\/strong><\/p>\n\n\n\n<p><strong>A very common&nbsp;side effect of emgality is<\/strong>&nbsp;(can occur in more than 1 in 10):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Injection site <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/brain-and-nerves\/pain\/\">pain<\/a><\/li><li>Injection site reactions (eg skin redness,&nbsp;itching, bruising, swelling).<\/li><\/ul>\n\n\n\n<p><strong>Common&nbsp;mgality side effects&nbsp;are<\/strong>&nbsp;(may affect up to 1 in 10):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Dizziness or tingling sensation<\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/constipation\/\">Constipation<\/a><\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/dry-skin-and-itching\/\">Itching<\/a><\/li><li>Rash<\/li><\/ul>\n\n\n\n<p><strong>Less common side effects&nbsp;are<\/strong>&nbsp;(may affect up to 1 in 100):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Hives&nbsp;(increase itchy rash on the skin).<\/li><\/ul>\n\n\n\n<p><strong>Reporting of&nbsp;side effects&nbsp;ar<\/strong><\/p>\n\n\n\n<p>If you get&nbsp;any <em>side effects of emgality<\/em>, talk to your doctor, pharmacist, or nurse.&nbsp;This also applies to any&nbsp;side effects&nbsp;not mentioned in this information.&nbsp;You can also report&nbsp;side effects directly via the national reporting system to:<\/p>\n\n\n\n<p>The Medical Products Agency<\/p>\n\n\n\n<p>Box 26<\/p>\n\n\n\n<p>SE-751 03 Uppsala<\/p>\n\n\n\n<p>By reporting&nbsp;side effects, you can help increase drug safety information.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Emgality<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Keep this medicine out of the sight and reach of children.<\/li><li>Do not use this medicine after the expiry date which is stated on the label and the carton after \u201cEXP\u201d.&nbsp;The expiration date is the last day of the specified month.<\/li><li>Store in a refrigerator (2 \u00b0 C &#8211; 8 \u00b0 C).&nbsp;Do not freeze.<\/li><li>Store in the original package.&nbsp;Sensitive to light.<\/li><li>This medicine can be stored outside the refrigerator for a single period of no more than 7 days when stored at temperatures not exceeding 30 \u00b0 C.&nbsp;If the pre-filled pen is stored at a higher temperature or for a longer period of time, it must be discarded.<\/li><li>Do not use this medicine if the pen is damaged or if the medicine is cloudy or contains particles.&nbsp;Medicines should not be disposed of via wastewater or household waste.<\/li><\/ul>\n\n\n\n<p>Ask your doctor, nurse, or pharmacist  <strong>how to dispose of Emgality pen<\/strong> no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents Of The Packaging And Other Information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content Declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is galkanezumab.&nbsp;One pre-filled&nbsp;pen&nbsp;contains 120 mg galkanezumab in 1 ml solution.<\/li><li>The other ingredients are <ul><li>L-histidine<\/li><li>L-histidine hydrochloride monohydrate<\/li><li>Polysorbate 80<\/li><li>Sodium chloride<\/li><li>Water for injections<\/li><\/ul><\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What The Medicine Looks Like And The Contents Of The Pack<\/h2>\n\n\n\n<p>Emgality is a solution for&nbsp;injection&nbsp;in a clear glass syringe.&nbsp;The color can vary from colorless to pale yellow.&nbsp;The syringe is enclosed in a single-use disposable pen.&nbsp;Available in packs of 1, 2, or 3 pre-filled pens.<\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder And Manufacturer<\/h2>\n\n\n\n<p><strong>Marketing Authorisation Holder<\/strong><\/p>\n\n\n\n<p><a href=\"https:\/\/www.lilly.nl\/\" rel=\"noopener\">Eli Lilly Nederland BV<\/a>, Papendorpseweg 83, 3528 BJ Utrecht, The Netherlands.<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Eli Lilly Italia SpA, Via Gramsci 731\/733, 50019, Sesto Fiorentino (FI), Italy.<br><\/p>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Emgality is a treatment medicine used for the precautionary treatment of migraine in adults.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2205,2200],"tags":[4467,4470,4469,4463,4466,4465,2213,4468,4464],"class_list":["post-8045","post","type-post","status-publish","format-standard","hentry","category-e","category-medicines","tag-emgality","tag-emgality-injection","tag-emgality-side-effects","tag-galkanezumab","tag-galkanezumab-injection","tag-galkanezumab-side-effects","tag-medicines","tag-what-is-emgality","tag-what-is-galkanezumab"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8045","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=8045"}],"version-history":[{"count":71,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8045\/revisions"}],"predecessor-version":[{"id":50261,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/8045\/revisions\/50261"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=8045"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=8045"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=8045"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}