metoprolol (a beta-blocker to treat high blood pressure and heart problems).<\/li><\/ul>\n\n\n\nEfexor Depot with food, drink, and alcohol<\/h2>\n\n\n\n
Efexor depot should be taken with a meal (see section 3 \u201cHow to take Efexor depot\u201d).
<\/p>\n\n\n\n
Avoid alcohol while taking Efexor Depot <\/p>\n\n\n\n
Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n
If you are pregnant or breast-feeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine. Do not use Efexor Depot until you have discussed the potential benefits and risks of your unborn baby with your doctor.
<\/p>\n\n\n\n
Tell your midwife and\/or doctor that you are using Efexor Depot. When similar drugs ( SSRIs ) are used during pregnancy, the risk of a serious condition called persistent pulmonary hypertension in the newborn (PPHN) may increase. This condition causes the baby to breathe faster and look blue. The symptoms usually appear within 24 hours of the baby being born. If this affects your baby, contact your midwife and\/or doctor immediately.
<\/p>\n\n\n\n
Other symptoms that your baby may have when it is born if you take this medicine during pregnancy are that the baby has difficulty breathing and does not eat properly. If your baby has these symptoms when it is born and you are worried, contact your doctor and\/or midwife who can advise you.
<\/p>\n\n\n\n
Efexor Depot passes into breast milk. There is a risk that the child will be affected. You should therefore talk to your doctor who will decide if you should stop breast-feeding or stop treatment with this medicine.<\/p>\n\n\n\n
Driving and using machines<\/h2>\n\n\n\n
Do not drive or use machines until you know how this medicine affects you.<\/p>\n\n\n\n
You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention. One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or side effects. Descriptions of these effects and side effects can be found in other sections. Read all the information in this leaflet for guidance. If you are not sure, talk to your doctor or pharmacist.
<\/p>\n\n\n\n
How to take Efexor Depot<\/h2>\n\n\n\n
Always take this medicine exactly as your doctor has told you. Ask your doctor or pharmacist if you are unsure.
<\/p>\n\n\n\n
The usual recommended starting dose for treating depression, generalized anxiety disorder, and social phobia is 75 mg per day. The dose can be increased gradually by your doctor and, if necessary, up to a maximum of 375 mg per day for depression. If you are being treated for panic disorder, your doctor will start with a lower dose(37.5 mg) and then increase the dose one step at a time. The highest dose for generalized anxiety disorder, social phobia, and panic disorder is 225 mg daily.
<\/p>\n\n\n\n
Take Efexor Depot at about the same time each day, either in the morning or in the evening. The capsules should be swallowed whole with liquid and must not be opened, crushed, chewed, or dissolved.
<\/p>\n\n\n\n
Efexor Depot should be taken with a meal.
<\/p>\n\n\n\n
If you have liver or kidney problems, talk to your doctor as your dose of this medicine may need to be changed.
<\/p>\n\n\n\n
Do not stop taking this medicine without first consulting your doctor (see section \u201cIf you stop taking Efexor Depot\u201d).<\/p>\n\n\n\n
If you take more Efexor Depot then you should<\/h2>\n\n\n\n
If you have taken too much of this medicine or if, for example, If a child has inadvertently ingested the medicine, contact a doctor, hospital, or the Poison Information Center for risk assessment and advice.
<\/p>\n\n\n\n
Symptoms of a possible overdose may include rapid heartbeat, changes in alertness (from drowsiness to coma ), blurred vision, seizures, and vomiting.<\/p>\n\n\n\n
If you forget to take Efexor Depot<\/h2>\n\n\n\n
If you miss a dose, take it as soon as you remember. However, if it is time for your next dose, skip the missed dose and only take one dose as usual. Do not take a double dose to make up for a forgotten dose Do not take more than the amount of Efexor Depot you have been prescribed per day.<\/p>\n\n\n\n
If you stop taking Efexor Depot<\/h2>\n\n\n\n
You should not stop taking the treatment or reduce the dose without first consulting your doctor, even if you feel better. If your doctor thinks you no longer need Efexor Depot, he\/she may ask you to reduce the dose slowly before stopping treatment completely. It is known that you may experience side effects when you stop taking this medicine, especially if you stop suddenly or if your dose is reduced too quickly. Some patients may experience symptoms such as suicidal ideation, aggression, fatigue, dizziness, intoxication, headache, insomnia, nightmares, dry mouth, loss of appetite, nausea, diarrhea, nervousness, anxiety, confusion, ringing in the ears, and crawling or, in rare cases, feeling of electric shock, weakness, sweating, seizures or flu-like symptoms, vision problems and high blood pressure (which may cause headache, dizziness, ringing in the ears, sweating, etc.).
<\/p>\n\n\n\n
Your doctor will tell you how to gradually stop taking Efexor Depot. This may take a few weeks or months. In some patients, it may need to be done gradually over several months or longer. If you get any of these or other symptoms that bother you, consult your doctor.
<\/p>\n\n\n\n
If you have any further questions on the use of this product, ask your doctor or pharmacist.
<\/p>\n\n\n\n
4. Possible side effects<\/h2>\n\n\n\n
Like all medicines, this medicine can cause side effects, although not everybody gets them.
<\/p>\n\n\n\n
If any of the following occur, do not take more Efexor Depot. Tell your doctor immediately, or go to the nearest emergency room.<\/strong>
<\/p>\n\n\n\nUncommon (may affect up to 1 in 100 people)<\/strong><\/p>\n\n\n\n- Swelling of the face, mouth, tongue, neck, hands, or feet and\/or a raised itchy rash ( hives ), difficulty swallowing or breathing.<\/li><\/ul>\n\n\n\n
Rare (may affect up to 1 in 1,000 people)<\/strong><\/p>\n\n\n\n- Chest tightness, wheezing, difficulty swallowing, or breathing.<\/li>
- Severe skin rash, itching, or hives (raised spots of red or pale skin that often itch).<\/li>
- Signs and symptoms of serotonergic symptoms such as restlessness, hallucinations, loss of coordination, rapid heartbeat, elevated body temperature, rapid changes in blood pressure, overactive reflexes, diarrhea, coma, nausea, vomiting.<\/li>
- In its most severe form, the serotonergic syndrome can resemble malignant neuroleptic syndrome (NMS). Signs and symptoms of NMS may include a combination of fever, rapid heartbeat, sweating, severe muscle stiffness, confusion, elevated levels of muscle enzymes (determined by blood tests).<\/li>
- Signs of infection, such as fever, chills, tremors, headache, sweating, flu-like symptoms. This may be due to a blood disease that leads to an increased risk of infection.<\/li>
- Severe rash, which can lead to severe blisters and scaly skin.<\/li>
- Unexplained muscle aches, tenderness, or weakness. This may be a sign of rhabdomyolysis.<\/li><\/ul>\n\n\n\n
Has been reported (occurs in an unknown number of users)<\/strong><\/p>\n\n\n\n- Signs and symptoms of a condition called “stress cardiomyopathy” may include chest pain, shortness of breath, dizziness, fainting, irregular heartbeat.<\/li><\/ul>\n\n\n\n
Other side effects that you should tell your doctor<\/strong> are (the frequency of these side effects is included in the list of ‘Other side effects that may occur’ below):<\/p>\n\n\n\n- Cough, wheezing, and shortness of breath, which may occur with fever.<\/li>
- Black (tar-like) stool or blood in the stool.<\/li>
- Itching, yellowish skin or yellow eyes, or dark urine, which may be symptoms of an inflammation of the liver ( hepatitis ).<\/li>
- Heart problems, such as fast or irregular heart rate, high blood pressure.<\/li>
- Eye problems, such as blurred vision, dilated pupils.<\/li>
- Nerve problems, such as dizziness, tingling, and numbness, movement disorders (muscle spasms or stiffness), seizures.<\/li>
- Mental problems, such as hyperactivity and feelings of unusual elation.<\/li>
- Withdrawal symptoms (see section 3 \u201cHow to take Efexor depot, if you stop taking Efexor depot\u201d).<\/li>
- Prolonged bleeding – if you cut or injure yourself, it may take a little longer than. common for bleeding to stop.<\/li><\/ul>\n\n\n\n
Do not worry if you see small white grains in your stool after taking Efexor Depot<\/strong>. Inside the Efexor prolonged-release capsules are small white grains that contain the active substance venlafaxine. These grains are released from the capsule in your stomach. As the grains pass through the gastrointestinal tract, venlafaxine is slowly released. The shell of the grain remains undissolved and disappears along with your feces. Your dose of venlafaxine has been taken up, even if you see barley in your stool.<\/strong>
<\/p>\n\n\n\nOther side effects may occur<\/strong>
<\/p>\n\n\n\nVery common (may affect more than 1 user in 10)<\/strong><\/p>\n\n\n\n- Dizziness, headache, drowsiness.<\/li>
- Insomnia.<\/li>
- Nausea, dry mouth, constipation.<\/li>
- Sweating (even at night).<\/li><\/ul>\n\n\n\n
Common (may affect up to 1 in 10 people)<\/strong><\/p>\n\n\n\n- Loss of appetite.<\/li>
- Confusion, feeling of being separated from oneself, lack of orgasm, decreased libido, agitation, nervousness, abnormal dreams.<\/li>
- Tremors, a feeling of restlessness or an inability to sit or stand still, numbness and tingling, altered taste experience, increased muscle tension.<\/li>
- Visual disturbances including blurred vision, dilated pupils, the inability of the eye to automatically change focus from distant to near objects.<\/li>
- Ringing in the ears ( tinnitus ).<\/li>
- Fast heartbeat, palpitations.<\/li>
- High blood pressure, redness.<\/li>
- Shortness of breath, yawning.<\/li>
- Vomiting, diarrhea.<\/li>
- Mild skin rash, itching.<\/li>
- Need to urinate more often than usual, inability to urinate, difficulty urinating.<\/li>
- Irregular periods such as increased bleeding or more irregular bleeding, abnormal ejaculation\/orgasm (in men), erectile dysfunction ( impotence ).<\/li>
- Weakness ( asthenia ), fatigue, chills.<\/li>
- Weight gain, weight loss.<\/li>
- Elevated cholesterol.<\/li><\/ul>\n\n\n\n
Uncommon (may affect up to 1 in 100 people)<\/strong><\/p>\n\n\n\n- Overactivity, thoughtlessness, and reduced need for sleep (mania).<\/li>
- Hallucinations, feeling detached from reality, abnormal orgasm, lack of emotion, feeling of excessive arousal, gnashing of teeth.<\/li>
- Fainting, involuntary muscle movements, impaired coordination, and balance.<\/li>
- Dizziness (especially if you get up too fast), decreased blood pressure.<\/li>
- Bloody vomiting, black tar-like stools, or blood in the stools, which may indicate internal bleeding.<\/li>
- Sensitivity to sunlight, bruising, abnormal hair loss.<\/li>
- Inability to control urine.<\/li>
- Stiffness, spasms, and involuntary muscle movements.<\/li>
- Some change in liver enzyme levels in the blood.<\/li><\/ul>\n\n\n\n
Rare (may affect up to 1 in 1,000 people)<\/strong><\/p>\n\n\n\n- Seizures.<\/li>
- Cough, wheezing, shortness of breath, which may occur along with fever.<\/li>
- Altered perception of space and confusion, often in combination with hallucinations ( delirium ).<\/li>
- Excessive fluid intake (so-called SIADH).<\/li>
- Decreased sodium levels in the blood.<\/li>
- Severe pain in the eyes and impaired vision or blurred vision.<\/li>
- Abnormal, fast, or irregular heartbeat, which can lead to fainting.<\/li>
- Severe pain in the abdomen or back (which may indicate a serious illness in the abdomen, liver, or pancreas).<\/li>
- Itching, yellow skin or eyes, dark urine, or flu-like symptoms, which are signs of liver inflammation ( hepatitis ).<\/li><\/ul>\n\n\n\n
Very rare (may affect 1 in 10,000 users)<\/strong><\/p>\n\n\n\n- Prolonged bleeding, which may be a sign of a decrease in the number of platelets in the blood, leads to an increased risk of bruising or bleeding.<\/li>
- Abnormal production of breast milk.<\/li>
- Unexpected bleeding, e.g. bleeding gums, blood in the urine or bloody vomiting, or the appearance of unexpected bruising or ruptured blood vessels.<\/li><\/ul>\n\n\n\n
Has been reported (occurs in an unknown number of users)<\/strong><\/p>\n\n\n\n- Suicidal ideation and suicidal ideation, cases of suicidal ideation, and suicidal ideation have been reported during treatment with venlafaxine or immediately after stopping treatment (see section 2, What you need to know before taking Efexor Depot ).<\/li>
- Aggression.<\/li>
- Dizziness.<\/li><\/ul>\n\n\n\n
Efexor Depot sometimes causes side effects that you may not be aware of, such as high blood pressure or abnormal heartbeat, small changes in your blood levels of liver enzymes, sodium, or cholesterol. In more rare cases, the Efexor depot may impair the function of the platelets (platelets) in the blood, leading to an increased risk of bruising or bleeding. Therefore, your doctor may want to take blood samples from time to time, especially if you have been taking Efexor Depot for a long time.
<\/p>\n\n\n\n
5. How to store Efexor Depot<\/h2>\n\n\n\n
Keep this medicine out of the sight and reach of children.
<\/p>\n\n\n\n
Do not use this medicine after the expiry date which is stated on the carton. The expiration date is the last day of the specified month.
<\/p>\n\n\n\n
Do not store above 30 \u00b0 C.
<\/p>\n\n\n\n
Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.<\/p>\n\n\n\n
6. Contents of the packaging and other information<\/h2>\n\n\n\nContent declaration<\/h2>\n\n\n\n
The active substance is venlafaxine.
<\/p>\n\n\n\n
Efexor Depot 37.5 mg:<\/p>\n\n\n\n
Each prolonged-release capsule contains 42.43 mg venlafaxine hydrochloride, equivalent to 37.5 mg venlafaxine-free bases.
<\/p>\n\n\n\n
Other ingredients are:<\/p>\n\n\n\n
Capsule contents:<\/em> microcrystalline cellulose, ethylcellulose, hypromellose, talc.<\/p>\n\n\n\nCapsule shell:<\/em> gelatin, black, red, and yellow iron oxide (E172), titanium dioxide (E171)<\/p>\n\n\n\nCapsule label:<\/em> shellac, red iron oxide (E172), ammonium hydroxide, simethicone, propylene glycol
<\/p>\n\n\n\nEfexor Depot 75 mg:<\/p>\n\n\n\n
Each prolonged-release capsule contains 84.85 mg venlafaxine hydrochloride, equivalent to 75 mg venlafaxine free base.
<\/p>\n\n\n\n
Other ingredients are:<\/p>\n\n\n\n
Capsule contents:<\/em> microcrystalline cellulose, ethylcellulose, hypromellose, talc<\/p>\n\n\n\nCapsule shell:<\/em> gelatin, red and yellow iron oxide (E172), titanium dioxide (E171)<\/p>\n\n\n\nCapsule label:<\/em> shellac, red iron oxide (E172), ammonium hydroxide, simethicone, propylene glycol
<\/p>\n\n\n\nEfexor Depot 150 mg:<\/p>\n\n\n\n
Each prolonged-release capsule contains 169.7 mg venlafaxine hydrochloride, equivalent to 150 mg venlafaxine free base.
<\/p>\n\n\n\n
Other ingredients are:<\/p>\n\n\n\n
Capsule contents:<\/em> microcrystalline cellulose, ethylcellulose, hypromellose, talc<\/p>\n\n\n\nCapsule shell:<\/em> gelatin, red and yellow iron oxide (E172), titanium dioxide (E171)<\/p>\n\n\n\nCapsule labeling:<\/em> shellac, sodium hydroxide, povidone, titanium dioxide (E171), propylene glycol<\/p>\n\n\n\nWhat the medicine looks like and the contents of the pack<\/h2>\n\n\n\n
Efexor Depot 37.5 mg is a peach-colored and gray opaque hard prolonged-release capsule (gelatin) 15.9 mm x 5.82 mm marked with ‘W’ and strength ’37 .5 ‘with red ink.<\/p>\n\n\n\n
Efexor Depot 37.5 mg is available in:<\/p>\n\n\n\n
Blister packs of 7, 10, 14, 20, 21, 28, 30, 35, 50, 60, 84, 100 and hospital packs of 70 (10×7, 1×70) or in cans of 7, 14, 20, 21, 35, 50, 100 and hospital packaging of 70 pieces.
<\/p>\n\n\n\n
Efexor Depot 75 mg is a peach-colored opaque hard prolonged-release capsule(gelatin) 19.4 mm x 6.91 mm marked with ‘W’ and strength ’75’ with red ink.<\/p>\n\n\n\n
Efexor Depot 75 mg is available in:<\/p>\n\n\n\n
Blister packs of 7, 10, 14, 15, 20, 28, 30, 50, 56, 60, 84, 98, 100 and hospital packs of 500 (10×50) and 1000 (10×100) or in cans of 14, 20, 50, 100 and hospital packages of 500 and 1000 pieces.
<\/p>\n\n\n\n
Efexor Depot 150 mg is a brick red opaque hard prolonged-release capsule (gelatin) 23.5 mm x 7.65 mm marked \u201cW\u201d and \u201c150\u201d in white ink.<\/p>\n\n\n\n
Efexor Depot 150 mg is available in:<\/p>\n\n\n\n
Blister packs of 7, 10, 14, 15, 20, 28, 30, 50, 56, 60, 84, 98, 100 and hospital packs of 500 (10×50) and 1000 (10×100) or in cans of 14, 20, 50, 100 and hospital packages of 500 and 1000 pieces.
<\/p>\n\n\n\n
Not all pack sizes may be marketed.<\/p>\n\n\n\n
Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n
Pfizer AB<\/p>\n\n\n\n
191 90 Sollentuna<\/p>\n\n\n\n
Tel: 08-550 520 00<\/p>\n\n\n\n
Email: eumedinfo@pfizer.com
<\/p>\n\n\n\n
Manufacturer:<\/strong><\/p>\n\n\n\nPfizer Ireland Pharmaceuticals<\/p>\n\n\n\n
Little Connell<\/p>\n\n\n\n
Newbridge<\/p>\n\n\n\n
County Kildare, Ireland
<\/p>\n\n\n\n
Pfizer Manufacturing Deutschland GmbH<\/p>\n\n\n\n
Company Freiburg<\/p>\n\n\n\n
Mooswaldallee 1<\/p>\n\n\n\n
D-79090 Freiburg<\/p>\n\n\n\n
Germany
<\/p>\n","protected":false},"excerpt":{"rendered":"
Efexor Depot is a treatment for adults with depression. It is also a treatment for adults with the following anxiety disorders: generalized anxiety disorder, social phobia (fear of or avoidance of social situations), and panic disorder (panic attacks). It is important to treat depression or anxiety disorders properly to help you feel better. If the condition is not treated, it may not go away but become more serious and more difficult to treat.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2205,2200],"tags":[4681,4684,4683,2213,4677,4680,4679,4682,4678],"class_list":["post-7960","post","type-post","status-publish","format-standard","hentry","category-e","category-medicines","tag-efexor-depot","tag-efexor-depot-capsule","tag-efexor-depot-side-effects","tag-medicines","tag-venlafaxine","tag-venlafaxine-capsules","tag-venlafaxine-side-effects","tag-what-is-efexor-depot","tag-what-is-venlafaxine"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7960","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=7960"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7960\/revisions"}],"predecessor-version":[{"id":10697,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7960\/revisions\/10697"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=7960"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=7960"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=7960"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}