{"id":7805,"date":"2021-03-01T07:32:11","date_gmt":"2021-03-01T07:32:11","guid":{"rendered":"https:\/\/zeepedia.com\/?p=7805"},"modified":"2021-05-11T09:53:46","modified_gmt":"2021-05-11T09:53:46","slug":"duotrav","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/duotrav\/","title":{"rendered":"DuoTrav &#8211; Travoprost uses, dose and side effects"},"content":{"rendered":"\n<p> 40 micrograms \/ ml + 5 mg \/ ml\u00a0eye drops\u00a0Solution<br><a href=\"https:\/\/zeepedia.com\/medical\/medicines\/travatan\/\">Travoprost<\/a><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What DuoTrav is and what it is used for<\/h2>\n\n\n\n<p>DuoTrav&nbsp;eye drops, the solution is a combination of two active substances (travoprost and&nbsp;timolol&nbsp;).&nbsp;Travoprost is a&nbsp;prostaglandin analog, which works by increasing the outflow of fluid in the eye, which lowers the pressure in the eye.&nbsp;Timolol&nbsp;is a&nbsp;beta-blocker, which works by reducing the production of fluid in the eye.&nbsp;The two substances work together to reduce eye pressure.<br><\/p>\n\n\n\n<p>DuoTrav is used to treat high pressure in the eye in adults, including the elderly.&nbsp;Too high pressure can lead to a disease called&nbsp;glaucoma.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2. What you need to know before using DuoTrav<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use DuoTrav<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to travoprost,&nbsp;prostaglandins,&nbsp;timolol,&nbsp;beta-blockers,&nbsp;or any of the other ingredients of this medicine (listed in section 6).<\/li><li>if you currently have or have ever had breathing problems such as&nbsp;asthma, severe&nbsp;chronic&nbsp;obstructive&nbsp;bronchitis&nbsp;(severe lung disease that may cause wheezing, difficulty breathing, and\/or persistent cough), or other types of breathing problems<\/li><li>if you have severe hay fever<\/li><li>if you have a slow heart rate,&nbsp;heart failure,&nbsp;or a condition that affects your heart rhythm (irregular heartbeat)<\/li><li>if the surface of your eye is cloudy<\/li><\/ul>\n\n\n\n<p>Ask your doctor for advice if any of these affect you.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Talk to your doctor before using DuoTrav if you currently have or have ever had:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>coronary heart disease (symptoms may include pain or tightness in the chest, shortness of breath, or suffocation),&nbsp;heart failure, low&nbsp;blood pressure.<\/li><li>heart rate disorders such as&nbsp;slow heartbeat.<\/li><li>respiratory problems,&nbsp;asthma,&nbsp;or&nbsp;chronic obstructive pulmonary disease.<\/li><li>disease with impaired blood circulation (eg&nbsp;Raynaud&#8217;s disease&nbsp;or Raynaud&#8217;s syndrome).<\/li><li>diabetes&nbsp;(because&nbsp;timolol&nbsp;can mask the signs and symptoms of low blood sugar).<\/li><li>overactive&nbsp;thyroid gland&nbsp;(because&nbsp;timolol&nbsp;can mask signs and symptoms).<\/li><li>myasthenia gravis&nbsp;(&nbsp;chronic&nbsp;neuromuscular weakness).<\/li><li>operated on cataracts.<\/li><li>eye inflammation.<\/li><\/ul>\n\n\n\n<p>If you are going to have any kind of surgery, tell your doctor that you are using DuoTrav as&nbsp;timolol&nbsp;may alter the effects of certain medicines used during&nbsp;anesthesia.<br><\/p>\n\n\n\n<p>If you get a severe&nbsp;allergic reaction&nbsp;(skin rash,&nbsp;redness,&nbsp;or&nbsp;itching&nbsp;of the eye) when using DuoTrav, for whatever reason, it is possible that adrenaline treatment will not help as usual.&nbsp;When you receive any other treatment, tell your doctor that you are being treated with DuoTrav.<br><\/p>\n\n\n\n<p>DuoTrav can change the color of the&nbsp;iris&nbsp;(the colored part of your eye).&nbsp;This change may be permanent.<br><\/p>\n\n\n\n<p>DuoTrav can increase the length, thickness, color, and\/or a number of your&nbsp;eyelashes and can cause unusual hair growth on your eyelids.<br><\/p>\n\n\n\n<p>Travoprost can be absorbed through the skin and should therefore not be used by women who are pregnant or trying to conceive.&nbsp;If the medicine comes in contact with the skin, wash it off immediately.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Children<\/h2>\n\n\n\n<p>DuoTrav is not intended for use by children and adolescents under 18 years of age.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and DuoTrav<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines, including medicines obtained without a prescription.<br><\/p>\n\n\n\n<p>DuoTrav can affect or be affected by other medicines that you use, including other&nbsp;eye drops&nbsp;for the treatment of&nbsp;glaucoma.&nbsp;Tell your doctor if you use or plan to use medicines for high&nbsp;blood pressure, heart medicines such as&nbsp;quinidine&nbsp;(used to treat heart conditions and certain types of&nbsp;malaria&nbsp;), medicines for&nbsp;diabetes,&nbsp;or the antidepressants&nbsp;fluoxetine&nbsp;or&nbsp;paroxetine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n<p>If you are pregnant or breast-feeding, think you may be pregnant or are planning to have a baby, ask your doctor for advice before using this medicine.<br><\/p>\n\n\n\n<p>Do not use DuoTrav if you are pregnant unless your doctor considers it necessary.&nbsp;If you are likely to become pregnant, you must use effective contraception when using this medicine.<br><\/p>\n\n\n\n<p>Do not use DuoTrav if you are breast-feeding.&nbsp;DuoTrav can go into breast milk<strong>.<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>You may find that your vision becomes foggy immediately after taking DuoTrav.&nbsp;DuoTrav may also cause hallucinations, dizziness, nervousness, or fatigue in some patients.<br><\/p>\n\n\n\n<p>Do not drive or use any tools or machines until these symptoms have disappeared.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">DuoTrav contains macrogol glycerol hydroxy stearate (hydrogenated castor oil) and propylene glycol,<\/h2>\n\n\n\n<p>which can cause skin reactions and skin irritation.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. How to use DuoTrav<\/h2>\n\n\n\n<p>Always use this medicine exactly as your doctor has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<br><\/p>\n\n\n\n<p>The recommended&nbsp;dose&nbsp;is<\/p>\n\n\n\n<p>a drop in the affected eye or eyes, once daily in the morning or evening.&nbsp;Take DuoTrav at the same time each day.<br><\/p>\n\n\n\n<p>Use DuoTrav in both eyes only if your doctor has prescribed it.<\/p>\n\n\n\n<p>DuoTrav should only be used as&nbsp;eye drops.<\/p>\n\n\n\n<figure class=\"wp-block-image\"><a href=\"https:\/\/www.fass.se\/LIF\/product?userType=2&amp;nplId=20050715000097#\" rel=\"noopener\"><img decoding=\"async\" src=\"https:\/\/www.fass.se\/imaging\/resources\/7bf1056b-d807-4b03-85c2-7d8700b413a3\" alt=\"Administration\"\/><\/a><\/figure>\n\n\n\n<ul class=\"wp-block-list\"><li>Immediately before using a bottle for the first time, open the protective bag (Fig. 1) and remove the bottle and note the date when you opened the bottle in the space on the label.<\/li><li>Make sure you have a mirror available.<\/li><li>Wash your hands.<\/li><li>Unscrew the bottle cap.<\/li><li>Hold the bottle upside down between your thumb and fingers.<\/li><li>Tilt your head back.&nbsp;Pull down the lower eyelid with a clean finger so that a &#8220;pocket&#8221; is formed between the eyelid and the eye.&nbsp;The drop should end up here (picture 2).<\/li><li>Hold the drip tip close to the eye.&nbsp;Use the mirror if it helps.<\/li><li>Do not touch the eye or eyelid, surrounding areas, or other surfaces with the drip tip.&nbsp;It can contaminate the drops.<\/li><li>Gently press on the bottle to release one drop of DuoTrav at a time (Figure 3).&nbsp;If a drop misses the eye, try again.<\/li><li>After taking DuoTrav, press with your finger in the corner of your eye next to your nose for 2 minutes (picture 4).&nbsp;This prevents DuoTrav from entering the rest of the body.<\/li><li>If you are going to use DuoTrav in both eyes, repeat the above steps for your other eye.<\/li><li>Screw on the lid firmly immediately after use.<\/li><li>Use only one bottle at a time.&nbsp;Do not open the protective bag until you need to use the bottle.<\/li><\/ul>\n\n\n\n<p>Use DuoTrav for as long as your doctor tells you to.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you use more DuoTrav than you should&nbsp;<\/h2>\n\n\n\n<p>If you have used too much DuoTrav,&nbsp;rinse everything out with warm water.&nbsp;Do not take any more drops until it is time for your next regular&nbsp;dose.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to use DuoTrav<\/h2>\n\n\n\n<p>If you forget to use DuoTrav,&nbsp;continue with the next&nbsp;dose&nbsp;as planned.&nbsp;Do not take a double&nbsp;dose&nbsp;to make up for a forgotten&nbsp;dose.&nbsp;Dose&nbsp;one should not exceed one drop in each affected eye per day.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop using DuoTrav<\/h2>\n\n\n\n<p>If you stop using DuoTrav without talking to your doctor, the pressure in your eye can not be controlled and this can lead to vision loss.<br><\/p>\n\n\n\n<p>If you are using other&nbsp;eye drops&nbsp;in addition to DuoTrav, wait at least 5 minutes between taking DuoTrav and the other drops.<br><\/p>\n\n\n\n<p>If you wear soft contact lenses, do not use the drops with the contact lenses left in your eyes.&nbsp;Wait for 15 minutes after dripping the eye drops, before putting the lenses back in the eyes.<br><\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects,&nbsp;although not everybody gets them.<br><\/p>\n\n\n\n<p>You can usually continue to use the drops unless the&nbsp;side effects&nbsp;are severe.&nbsp;If you are concerned, talk to a doctor or pharmacist.&nbsp;Do not stop using DuoTrav without talking to your doctor.<br><\/p>\n\n\n\n<p><strong>Very common&nbsp;side effects&nbsp;(may affect more than 1 user in 10)<\/strong><br><\/p>\n\n\n\n<p><em>Effects in the eyes<\/em><\/p>\n\n\n\n<p>Blushing.<br><\/p>\n\n\n\n<p><strong>Common&nbsp;side effects&nbsp;(may affect up to 1 in 10 people)<\/strong><br><\/p>\n\n\n\n<p><em>Effects in the eyes<\/em><\/p>\n\n\n\n<p>Inflammation&nbsp;of the surface of the eye with surface damage, eye pain, blurred vision, abnormal vision, dry eyes,&nbsp;itchy&nbsp;eyes, eye discomfort, signs and symptoms of eye irritation (eg burning, pain).<br><\/p>\n\n\n\n<p><strong>Less common&nbsp;side effects&nbsp;are&nbsp;<\/strong><strong>(may affect up to 1 in 100)<\/strong><br><\/p>\n\n\n\n<p><em>Effects in the eyes<\/em><\/p>\n\n\n\n<p>Inflammation&nbsp;of the eye surface,&nbsp;inflammation&nbsp;of the eyelid, swollen&nbsp;conjunctiva, increased growth of the&nbsp;eyelashes, iris inflammation, eye inflammation, photosensitivity, impaired vision, tired eyes, eye allergy, eye swelling, increased tear production, eyelid redness, change in eyelid color, darker skin (round skin).<br><\/p>\n\n\n\n<p><em>General effects<\/em><\/p>\n\n\n\n<p>Allergic reaction&nbsp;to active substance, dizziness, headache, increased or decreased&nbsp;blood pressure, shortness of breath, increased hair growth, drip at the back of the throat, inflammation of the skin and&nbsp;itching, slower heartbeat.<br><\/p>\n\n\n\n<p><strong>Rare&nbsp;side effects&nbsp;are&nbsp;<\/strong><strong>(may affect up to 1 in 1000)<\/strong><br><\/p>\n\n\n\n<p><em>Effects in the eyes<\/em><\/p>\n\n\n\n<p>Thinning of the surface of the eye,&nbsp;inflammation&nbsp;of the eyelid glands, ruptured blood vessels in the eye, crust formation on the eyelids, abnormally placed&nbsp;eyelashes, abnormally increased growth of the&nbsp;eyelashes.<br><\/p>\n\n\n\n<p><em>General effects<\/em><\/p>\n\n\n\n<p>Nervousness, irregular heartbeat, hair loss, voice problems, difficulty breathing, cough, throat irritation, hives, abnormal liver values, skin discoloration, thirst, fatigue, discomfort inside the nose, colored urine, pain in hands, and feet.<br><\/p>\n\n\n\n<p><strong>Has been reported (occurs in an unknown number of users)<\/strong><br><\/p>\n\n\n\n<p><em>Effects in the eyes<\/em><\/p>\n\n\n\n<p>Drooping eyelids (keeps the eye half-closed), sunken eyes, changed the color of the&nbsp;iris(colored part of the eye).<br><\/p>\n\n\n\n<p><em>General effects<\/em><\/p>\n\n\n\n<p>Rash,&nbsp;heart failure, chest pain,&nbsp;stroke, fainting, depression,&nbsp;asthma, increased heart rate, numbness or tingling sensation, palpitations, swelling in the lower legs, bad taste in the mouth.<br><\/p>\n\n\n\n<p><strong>Also:<\/strong><\/p>\n\n\n\n<p>DuoTrav is a combination of two active substances, travoprost and&nbsp;timolol.&nbsp;Like other medicines that are administered (given) to the eyes, travoprost and&nbsp;timolol&nbsp;(a&nbsp;beta-blocker&nbsp;)&nbsp;are absorbed&nbsp;into the bloodstream.&nbsp;This can have similar&nbsp;side effects as those observed when&nbsp;beta-blockers&nbsp;are administered orally or by&nbsp;injection.&nbsp;The incidence of&nbsp;side effects&nbsp;after&nbsp;administration&nbsp;to the eyes is lower than after&nbsp;administration&nbsp;by mouth or by&nbsp;injection.<br><\/p>\n\n\n\n<p>The following&nbsp;side effects&nbsp;have not been reported with DuoTrav but include reactions seen in the&nbsp;beta-blocker&nbsp;class&nbsp;when used to treat eye conditions or reactions seen with travoprost alone:<br><\/p>\n\n\n\n<p><strong>Eye effects<\/strong><\/p>\n\n\n\n<p>Inflammation&nbsp;of the eyelid,&nbsp;inflammation&nbsp;of the cornea, loosening of the layer under the retina that contains blood vessels after filtration surgery, which can cause visual disturbances, decreased sensitivity of the cornea,&nbsp;erosion&nbsp;of the cornea (damage to the anterior layer of the eyeball), double vision, runny eye, swelling around the eye,&nbsp;itching&nbsp;of the eyelids, the eyelid is turned outwards with&nbsp;redness irritation and increased tearing, blurred vision (signs of cloudiness of the eye lens), swelling of a part of the eye (uvea),&nbsp;eczema&nbsp;of the eyelids, halo effect (light rings around a point of light), decreased sensation in the eye,&nbsp;pigmentation&nbsp;inside the eye, enlarged (dilated)&nbsp;pupils, discoloration eyelashes, the altered texture of the&nbsp;eyelashes, abnormal&nbsp;field of vision.<br><\/p>\n\n\n\n<p><strong>General effects<\/strong><\/p>\n\n\n\n<p><em>Ears and balance organs<\/em>: dizziness along with a feeling of tingling, ringing in the ears.<br><\/p>\n\n\n\n<p><em>Heart and blood circulation<\/em>: slow heartbeat, palpitations,&nbsp;edema&nbsp;(fluid retention), change in heart rate or rate,&nbsp;chronic&nbsp;heart failure&nbsp;(heart disease with shortness of breath and swelling of the feet and legs due to fluid retention), a type of palpitations, low&nbsp;blood pressure,&nbsp;myocardial infarction&nbsp;phenomena, cold hands, and feet, decreased blood supply to the brain.<br><\/p>\n\n\n\n<p><em>Respiratory<\/em>&nbsp;tract: contraction of the airways in the lungs (especially in patients with pre-existing disease), runny nose or nasal congestion, sneezing (due to&nbsp;allergies&nbsp;), difficulty breathing, nosebleeds, dryness of the nose.<br><\/p>\n\n\n\n<p><em>Nervous system and general symptoms<\/em>: difficulty sleeping (insomnia), nightmares, memory loss, hallucinations, loss of strength and energy, anxiety (excessive emotional distress).<br><\/p>\n\n\n\n<p><em>Gastrointestinal disorders<\/em>: taste changes, nausea, stomach upset, diarrhea,&nbsp;dry mouth, abdominal pain, vomiting, and constipation.<br><\/p>\n\n\n\n<p><em>Allergy<\/em>: increased allergic symptoms, generalized allergic reactions, including swelling under the skin that may occur in places such as.&nbsp;face and arms and legs and may obstruct the airways which may cause difficulty in swallowing or breathing, limited and generalized rash,&nbsp;itching, severe, sudden life-threatening&nbsp;allergic reaction.<br><\/p>\n\n\n\n<p><em>Skin<\/em>: rash with white silvery-colored appearance (psoriasis-like rash) or worsening of&nbsp;psoriasis, scaly skin, abnormal hair quality,&nbsp;inflammation&nbsp;of the skin with itchy rash and&nbsp;redness, altered hair color, loss of&nbsp;eyelash&nbsp;scars,&nbsp;itching, abnormal hair growth, skin redness.<br><\/p>\n\n\n\n<p><em>Muscles <\/em>increased signs and symptoms of&nbsp;myasthenia gravis&nbsp;(muscle disorder), unusual sensations such as&nbsp;tingling in the skin.&nbsp;Muscle weakness\/muscle fatigue, muscle pain not caused by exercise, joint pain.<br><\/p>\n\n\n\n<p><em>Kidneys and urinary tract<\/em>: difficulty and pain when urinating, involuntary urine leakage.<br><\/p>\n\n\n\n<p><em>Reproductive organs<\/em>: Decreased sexual ability, decreased sexual desire.<br><\/p>\n\n\n\n<p><em>Metabolism<\/em>: low blood sugar, elevated prostate-specific antigen.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store DuoTrav<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<br><\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the bottle and the carton after EXP.&nbsp;The expiration date is the last day of the specified month.<br><\/p>\n\n\n\n<p>Do not store above 30 \u00b0 C<br><\/p>\n\n\n\n<p>You must discard the bottle 4 weeks after opening it, to prevent the risk of&nbsp;infection, and take a new bottle.&nbsp;Each time you start a new bottle, write down the date you opened it on the designated space on the bottle and carton.<br><\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substances are travoprost and&nbsp;timolol.&nbsp;One ml solution contains 40 micrograms of travoprost and 5 mg&nbsp;timolol&nbsp;(as <a href=\"https:\/\/zeepedia.com\/medical\/medicines\/timosan\/\">timolol<\/a> maleate).<br><\/li><li>The other ingredients are polyquaternium-1, mannitol (E421), propylene glycol (E1520), macrogol glycerol hydroxy stearate (hydrogenated castor oil), boric acid, sodium chloride, sodium hydroxide or&nbsp;hydrochloric acid&nbsp;(to adjust the&nbsp;pH&nbsp;), and purified water.&nbsp;Small amounts of sodium hydroxide or&nbsp;hydrochloric acid&nbsp;are added to keep the acidity (&nbsp;pH&nbsp;) normal.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>DuoTrav is a liquid (a clear, colorless solution) supplied in a 2.5 ml plastic bottle with a screw cap.&nbsp;Each bottle is packed in a protective bag.<br><\/p>\n\n\n\n<p>Packs of 1, 3, or 6 bottles.<br><\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorisation Holder<\/h2>\n\n\n\n<p>Novartis Europharm Limited<\/p>\n\n\n\n<p>Vista Building<\/p>\n\n\n\n<p>Elm Park, Merrion Road<\/p>\n\n\n\n<p>Dublin 4<\/p>\n\n\n\n<p>Ireland<br><\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>SA Alcon-Couvreur NV<\/p>\n\n\n\n<p>Rijksweg 14<\/p>\n\n\n\n<p>B-2870 Puurs<\/p>\n\n\n\n<p>Belgium<br><\/p>\n\n\n\n<p>Alcon Cus\u00ed, SA<\/p>\n\n\n\n<p>Camil Fabra 58<\/p>\n\n\n\n<p>08320 El Masnou<\/p>\n\n\n\n<p>Spain<br><\/p>\n\n\n\n<p>Contact the representative of the marketing authorization holder to find out more about this medicine:<\/p>\n\n\n\n<figure class=\"wp-block-table\"><table><tbody><tr><td>Belgium \/ Belgique \/ BelgienNovartis Pharma NVTel: +32 2 246 16 11<\/td><td>LithuaniaSIA Novartis Baltics Lithuanian branchesTel: +370 5 269 16 50<\/td><\/tr><tr><td>BulgariaNovartis Bulgaria EOODTel .: +359 2 489 98 28<\/td><td>Luxembourg \/ LuxemburgNovartis Pharma NVTel: +32 2 246 16 11<\/td><\/tr><tr><td>Czech RepublicNovartis sroTel: +420 225 775 111<\/td><td>HungaryNovartis Hungary Kft.Tel .: +36 1 457 65 00<\/td><\/tr><tr><td>DenmarkNovartis Healthcare A \/ STel: +45 39 16 84 00<\/td><td>MaltaNovartis Pharma Services Inc.Tel: +356 2122 2872<\/td><\/tr><tr><td>GermanyNovartis Pharma GmbHTel: +49 911 273 0<\/td><td>The NetherlandsNovartis Pharma BVTel: +31 88 04 52 111<\/td><\/tr><tr><td>EestiSIA Novartis Baltics Lithuanian branchTel: +372 66 30 810<\/td><td>NorwayNovartis Norge ASTel: +47 23 05 20 00<\/td><\/tr><tr><td>GreeceNovartis (Hellas) AEBE:\u0397\u03bb: +30 210 281 17 12<\/td><td>AustriaNovartis Pharma GmbHTel: +43 1 86 6570<\/td><\/tr><tr><td>SpainNovartis Pharmac\u00e9utica, SATel: +34 93 306 42 00<\/td><td>PolandNovartis Poland Sp.&nbsp;z ooTel .: +48 22 375 4888<\/td><\/tr><tr><td>FranceNovartis Pharma SASTel: +33 1 55 47 66 00<\/td><td>PortugalNovartis Farma &#8211; Pharmaceutical Products, SATel: +351 21 000 8600<\/td><\/tr><tr><td>CroatiaNovartis Hrvatska dooTel.&nbsp;+385 1 6274 220<\/td><td>RomaniaNovartis Pharma Services Romania SRLTel: +40 21 31299 01<\/td><\/tr><tr><td>IrelandNovartis Ireland LimitedTel: +353 1 260 12 55<\/td><td>SloveniaNovartis Pharma Services Inc.Tel: +386 1 300 75 50<\/td><\/tr><tr><td>IcelandVistor hf.Phone: +354 535 7000<\/td><td>Slovak RepublicNovartis Slovakia sroTel: + 421 2 5542 5439<\/td><\/tr><tr><td>ItalyNovartis Farma SpATel: +39 02 96 54 1<\/td><td>Finland \/ FinlandNovartis Finland OyPuh \/ Tel: +358 (0) 10 6133 200<\/td><\/tr><tr><td>LatviaSIA Novartis BalticsTel: +371 67 887 070<\/td><td>United KingdomNovartis Pharmaceuticals UK Ltd.Tel: +44 1276 698370<\/td><\/tr><\/tbody><\/table><\/figure>\n","protected":false},"excerpt":{"rendered":"<p>DuoTrav eye drops, the solution is a combination of two active substances (travoprost and timolol ). Travoprost is a prostaglandin analog, which works by increasing the outflow of fluid in the eye, which lowers the pressure in the eye. Timolol is a beta-blocker, which works by reducing the production of fluid in the eye. The two substances work together to reduce eye pressure.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2204,2200],"tags":[4988,4991,4990,4501,2213,4984,4987,4986,4989,4985],"class_list":["post-7805","post","type-post","status-publish","format-standard","hentry","category-d","category-medicines","tag-duotrav","tag-duotrav-eye-drops","tag-duotrav-side-effects","tag-eye-drops","tag-medicines","tag-travoprost","tag-travoprost-eye-drops","tag-travoprost-side-effects","tag-what-is-duotrav","tag-what-is-travoprost"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7805","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=7805"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7805\/revisions"}],"predecessor-version":[{"id":10821,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7805\/revisions\/10821"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=7805"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=7805"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=7805"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}