2 mg \/ ml\u00a0concentrate for solution for\u00a0infusion\u00a0solution\u00a0
doxorubicin hydrochloride<\/p>\n\n\n\n
Doxorubicin Actavis belongs to a group of medicines called anthracyclines. Doxorubicin Actavis is used to treat the following types of cancer:<\/p>\n\n\n\n
Doxorubicin Actavis is also used in combination with other anticancer medicines.
<\/p>\n\n\n\n
Doxorubicin hydrochloride contained in Doxorubicin Actavis may also be approved for the treatment of other conditions not mentioned in this product information. Ask your doctor, pharmacist, or other healthcare professional if you have any further questions, and always follow their instructions.
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Talk to your doctor if any of the above apply to you.
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Do not take Doxorubicin Actavis intravenously<\/strong><\/p>\n\n\n\n Talk to your doctor if any of the above apply to you. Do not take Doxorubicin Actavis directly into the bladder<\/strong><\/p>\n\n\n\n Talk to your doctor if any of the above apply to you.<\/p>\n\n\n\n Talk to a doctor<\/strong><\/p>\n\n\n\n Doxorubicin severely reduces blood cell production in the bone marrow. It can make you more prone to infection or bleeding. Tell your doctor if you get a fever or other signs of infection or if you have any type of bleeding. Vaccination is not recommended. Avoid contact with people who have recently been vaccinated against polio. Doxorubicin Actavis should only be given under the supervision of a qualified doctor who has experience in cancer treatment. All patients must be checked carefully and often e.g. how the blood picture looks like and for how the heart, liver, and kidneys work. Contact a doctor or other healthcare professional immediately if you feel a burning or burning sensation at the infusion site. Such pain can occur if the drug leaks out of the vein and you then need to receive appropriate treatment.<\/p>\n\n\n\n Tell your doctor or pharmacist if you are taking or have recently taken or might take any other medicines. This is especially important for:<\/p>\n\n\n\n If you are pregnant or breast-feeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n <\/p>\n\n\n\n It is known from animal experiments that doxorubicin passes through the placenta and damages the fetus. Therefore, you should not use doxorubicin if you are pregnant. Tell your doctor immediately if you are or think you may be pregnant.<\/p>\n\n\n\n <\/p>\n\n\n\n Women treated with Doxorubicin Actavis should not become pregnant during and up to 6 months after treatment. Men treated with doxorubicin should ensure that their partner does not become pregnant during and up to 6 months after treatment. Sexually active men and women should therefore use an effective method of contraception during and up to 6 months after treatment.<\/p>\n\n\n\n <\/p>\n\n\n\n Doxorubicin can cause permanent infertility and men should therefore seek advice on storing (or freezing) semen before treatment. If you are considering having children after treatment, you should discuss it with your doctor. The drug passes into breast milk. Do not breast-feed while you are being treated with Doxorubicin Actavis.<\/p>\n\n\n\n Due to frequent nausea and vomiting, you are advised not to drive or use machines. You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires increased attention. One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or side effects. Descriptions of these effects and side effects can be found in other sections. Read all the information in this leaflet for guidance. If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n This medicine contains 18 mg of sodium (the main ingredient in table salt) in each 5 ml vial. This corresponds to 0.9% of the WHO’s recommended maximum intake for an adult.<\/p>\n\n\n\n This medicine contains 35 mg of sodium (the main ingredient in table salt) in each 10 ml vial. This corresponds to 1.8% of the WHO’s recommended maximum intake for an adult.<\/p>\n\n\n\n This medicine contains 88.5 mg of sodium (the main ingredient in table salt) in each 25 ml vial. This corresponds to 4.4% of the WHO’s recommended maximum intake for an adult.<\/p>\n\n\n\n This medicine contains 177 mg of sodium (the main ingredient in table salt) in each 50 ml vial. This corresponds to 8.9% of the WHO’s recommended maximum intake for an adult.<\/p>\n\n\n\n This medicine contains 266 mg of sodium (the main ingredient in table salt) in each 75 ml vial. This corresponds to 13.3% of the WHO’s recommended maximum intake for an adult.<\/p>\n\n\n\n This medicine contains 354 mg of sodium (the main ingredient in table salt) in each 100 ml vial This corresponds to 17.7% of the WHO recommended maximum intake for an adult.<\/p>\n\n\n\n <\/p>\n\n\n\n Doxorubicin Actavis should only be given under the supervision of a qualified doctor who has experience in cancer treatment. Methods of administration and routes of administration<\/em><\/p>\n\n\n\n You will be given the drug by intravenous infusion into a blood vessel under the supervision of a specialist. Do not take the medicine yourself. You will be monitored regularly, both during and after treatment. If you have superficial bladder cancer, the drug may be administered directly into the bladder ( installation ). This medicine should be diluted before use. Intravenous administration<\/em><\/p>\n\n\n\n Dose one is usually calculated based on body surface area. Doxorubicin Actavis can be given e.g. once a week, every three weeks, or even at longer intervals. Dosage one and how often the medicine should be given also depends on what other cancer medicines are used and on what disease you have and your general condition. Your doctor will decide what dose to take. Installation in the bladder<\/em><\/p>\n\n\n\n Dose one is 30-50 mg doxorubicin in 25-50 ml saline solution. The solution should be kept in the bladder for 1-2 hours. During this period, you must turn 90 degrees every 15 minutes. You should not drink anything for 12 hours before<\/em><\/strong> instilling one in the bladder to avoid diluting the drug with urine. Instillation one can be repeated at 1 week to 1-month intervals. Your doctor will determine how often installation is needed.<\/p>\n\n\n\n <\/p>\n\n\n\n Use for children and adolescents<\/strong><\/p>\n\n\n\n Dosage one should be reduced in children. Doctors will advise you on how much you need.<\/p>\n\n\n\n If you have ingested too much medicine or if e.g. if a child has inadvertently ingested the medicine, contact a doctor, hospital, or the Poison Information Center for risk assessment and advice<\/p>\n\n\n\n <\/p>\n\n\n\n Because a doctor will give you the medicine, it is unlikely that you will get an overdose. However, if you have any further questions, ask your doctor or nurse immediately.<\/p>\n\n\n\n In acute overdose, side effects such as sores in the mouth, reduced white blood cell counts, and platelets can worsen and can lead to heart problems. Your doctor will take appropriate action if you have an overdose. Heart problems can occur six months after an overdose.<\/p>\n\n\n\n Doctors decide how long you should be treated with Doxorubicin Actavis. If treatment is stopped before the planned treatment cycles have been completed, the treatment may have a worse effect. Ask your doctor if you want to stop treatment. If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n Like all medicines, this medicine can cause side effects, although not everybody gets them. Contact a doctor or healthcare professional immediately if you notice any of the following side effects:<\/strong><\/p>\n\n\n\n Very common (may affect more than 1 in 10 people)<\/em><\/p>\n\n\n\n Common (may affect up to 1 in 10 people)<\/em><\/p>\n\n\n\n Uncommon (may affect up to 1 in 100 people)<\/em><\/p>\n\n\n\n Rare (may affect up to 1 in 1,000 people)<\/em><\/p>\n\n\n\n Very rare (may affect up to 1 in 10,000 people)<\/em><\/p>\n\n\n\n Unknown <\/em>(frequency can not be calculated from available data)<\/em><\/p>\n\n\n\n Keep out of sight and reach of children.<\/p>\n\n\n\n <\/p>\n\n\n\n Do not use this medicine after the expiry date which is stated on the vial after EXP and the outer carton after EXP. dat. The expiration date is the last day of the specified month. Store in a refrigerator (2 \u00b0 C – 8 \u00b0 C). Keep the vial in the outer carton. Sensitive to light.<\/p>\n\n\n\n <\/p>\n\n\n\n Do not use this medicine unless it is clear, red, and free from particles. Any unused product or waste material should be disposed of by local requirements. Follow guidelines for handling cytotoxic drugs. Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.<\/p>\n\n\n\n Doxorubicin Actavis concentrate for solution for infusion is a clear, red liquid. Doxorubicin Actavis is packaged in clear glass vials with a rubber stopper and an aluminum seal with a polypropylene disc. Pack sizes:<\/p>\n\n\n\n 1 x 5 ml vial<\/p>\n\n\n\n 10 x 5 ml vial<\/p>\n\n\n\n 1 x 10 ml vial<\/p>\n\n\n\n 10 x 10 ml vial<\/p>\n\n\n\n 1x 25 ml vial<\/p>\n\n\n\n 1 x 50 ml vial<\/p>\n\n\n\n 1 x 75 ml vial<\/p>\n\n\n\n 1 x 100 ml vial Not all pack sizes may be marketed.<\/p>\n\n\n\n Actavis Group PTC ehf.<\/p>\n\n\n\n Reykjavikurvegur 76-78<\/p>\n\n\n\n 220 Hafnarfj\u00f6r\u00f0ur<\/p>\n\n\n\n Iceland Agent:<\/strong><\/p>\n\n\n\n SanoSwiss UAB<\/p>\n\n\n\n Aukstaiciu str. 26A<\/p>\n\n\n\n LT-44169 Kaunas<\/p>\n\n\n\n Lithuania<\/p>\n\n\n\n +370 700 01320<\/p>\n\n\n\n info@sanoswiss.com Doxorubicin Actavis belongs to a group of medicines called anthracyclines. Doxorubicin Actavis is used to treat the following types of cancer:<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2204,2200],"tags":[5193,5194,5177,5190,5189,5179,2213,5192,5178],"class_list":["post-7722","post","type-post","status-publish","format-standard","hentry","category-d","category-medicines","tag-doxorubicin-actavis-side-effects","tag-doxorubicin-actavis-uses","tag-doxorubicin-hydrochloride","tag-doxorubicin-hydrochloride-dose","tag-doxorubicin-hydrochloride-infusion","tag-doxorubicin-hydrochloride-side-effects","tag-medicines","tag-what-is-doxorubicin-actavis","tag-what-is-doxorubicin-hydrochloride"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7722","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=7722"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7722\/revisions"}],"predecessor-version":[{"id":10881,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7722\/revisions\/10881"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=7722"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=7722"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=7722"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
<\/p>\n\n\n\nWarnings and cautions<\/h2>\n\n\n\n
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<\/p>\n\n\n\nOther medicines and Doxorubicin Actavis<\/h2>\n\n\n\n
Pregnancy, breastfeeding, and fertility<\/h2>\n\n\n\n
<\/p>\n\n\n\nDriving and using machines<\/h2>\n\n\n\n
<\/p>\n\n\n\nDoxorubicin Actavis contains sodium<\/h2>\n\n\n\n
How to take Doxorubicin Actavis<\/h2>\n\n\n\n
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<\/p>\n\n\n\nIf you take more Doxorubicin Actavis then you should<\/h2>\n\n\n\n
If you forget to take Doxorubicin Actavis<\/h2>\n\n\n\n
<\/p>\n\n\n\n4. Possible side effects<\/h2>\n\n\n\n
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<\/li><\/ul>\n\n\n\n5. How to store Doxorubicin Actavis<\/h2>\n\n\n\n
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<\/p>\n\n\n\n6. Contents of the packaging and other information<\/h2>\n\n\n\n
Content declaration<\/h2>\n\n\n\n
What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n
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<\/p>\n\n\n\nMarketing Authorisation Holder<\/h2>\n\n\n\n
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