20 mg\u00a0film-coated tablets\u00a0
avatrombopag<\/p>\n\n\n\n
Doptelet contains an active substance called avatrombopag. It belongs to a group of medicines called thrombopoietin receptor agonists.
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Doptelet is used in adults with chronic liver disease to treat low platelet counts ( thrombocytopenia ) before a medical procedure that carries a risk of bleeding.
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Doptelet is used to treat adults with low platelet counts due to primary chronic immunological thrombocytopenia (ITP) when previous treatment with ITP (such as corticosteroids or immunoglobulins) has not worked well enough.<\/p>\n\n\n\n
Doptelet works by helping to increase the number of platelets in the blood. The platelets are blood cells that help the blood to coagulate and thus reduce or prevent bleeding.
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Talk to your doctor or pharmacist before taking Doptelet if:<\/p>\n\n\n\n
The risk of getting blood clots can be higher<\/strong> as you get older if:<\/p>\n\n\n\n If any of the above apply to you, or you are not sure, talk to your doctor or pharmacist before taking Doptelet. Blood tests to check the number of platelets<\/strong><\/p>\n\n\n\n If you stop taking Doptelet, the platelet count will probably be as low as before or even lower, leading to a risk of bleeding. This can happen within a few days. The platelet count will be checked and your doctor will discuss appropriate precautions with you. Tests to check the bone marrow a<\/strong><\/p>\n\n\n\n In people who have problems with the bone marrow, drugs such as Doptelet can make the problems worse. Signs of changes in the bone marrow may show abnormal results in blood tests. Your doctor may also take samples to directly check your bone marrow during treatment with Doptelet.<\/p>\n\n\n\n Do not give Doptelet to anyone under 18 years of age. The safety and efficacy of the drug in this age group are not known.<\/p>\n\n\n\n Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines. If you are taking other medicines for ITP, you may need to lower your dose or stop taking it while you are taking Doptelet.<\/p>\n\n\n\n If you are pregnant, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine. Doptelet is not recommended during pregnancy or in women of childbearing potential not using contraception. If you are breast-feeding, ask your doctor or pharmacist for advice before taking Doptelet. This medicine can pass into breast milk. Your doctor will help you determine if the benefits of breastfeeding outweigh the potential risks to your baby while breastfeeding.<\/p>\n\n\n\n Doptelet is not expected to affect the ability to drive, cycle or use tools or machines.<\/p>\n\n\n\n Doptelet contains lactose (a sugar). If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine. Always take this medicine exactly as your doctor or pharmacist has told you. Ask your doctor or pharmacist if you are unsure. If you have chronic liver disease and low platelet counts, your planned medical procedure should be performed within 5 to 8 days after the last dose of Doptelet. If you have chronic immunological thrombocytopenia, your doctor will tell you how much Doptelet to take and when to take it. How many doses<\/strong> should I take? If you have chronic liver disease and are about to undergo an invasive procedure<\/em><\/p>\n\n\n\n If you have chronic immunological thrombocytopenia<\/em><\/p>\n\n\n\n Take the medicine like this<\/strong><\/p>\n\n\n\n If you have chronic liver disease and low platelet counts<\/em><\/p>\n\n\n\n If you have chronic immunological thrombocytopenia<\/em><\/p>\n\n\n\n Take Doptelet for as long as your doctor tells you to. Do not stop taking Doptelet unless your doctor tells you to. If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n Like all medicines, this medicine can cause side effects, although not everybody gets them. Talk to your doctor or pharmacist if you get any of the following side effects. The following side effects have been reported with Doptelet treatment in adult patients with chronic liver disease:<\/strong> Common<\/strong> (may affect up to 1 in 10 people)<\/p>\n\n\n\n Uncommon<\/strong> (may affect up to 1 in 100 people)<\/p>\n\n\n\n The following adverse reactions have been reported with Doptelet treatment in adult patients with primary chronic immunological thrombocytopenia<\/strong> : Very common<\/strong> (may affect more than 1 in 10 people)<\/p>\n\n\n\n Common<\/strong> (may affect up to 1 in 10 people)<\/p>\n\n\n\n Common side effects are those that can show up in blood tests<\/strong><\/p>\n\n\n\n Uncommon<\/strong> (may affect up to 1 in 100 people)<\/p>\n\n\n\n Uncommon side effects can be seen in blood tests<\/strong><\/p>\n\n\n\n <\/p>\n\n\n\n Keep this medicine out of the sight and reach of children. Do not use this medicine after the expiry date which is stated on the carton and each blister after \u201cEXP\u201d. The expiration date is the last day of the specified month. No special storage instructions. Medicines should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.<\/p>\n\n\n\n Doptelet 20 mg film-coated tablets are light yellow, round, with a curved top and bottom, marked with \u201cAVA\u201d on one side and \u201c20\u201d on the other. The tablets are packed in cartons containing one or two blister cards made of aluminum. Each blister card contains 10 or 15 tablets.<\/p>\n\n\n\n Manufacturer<\/strong><\/p>\n\n\n\n Cilatus Manufacturing Services Limited<\/p>\n\n\n\n Regus House<\/p>\n\n\n\n Harcourt Center<\/p>\n\n\n\n Harcourt Road<\/p>\n\n\n\n Dublin 2<\/p>\n\n\n\n D02 HW77<\/p>\n\n\n\n Ireland Doptelet contains an active substance called avatrombopag. It belongs to a group of medicines called thrombopoietin receptor agonists.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2204,2200],"tags":[5257,5259,5260,5261,5263,5264,2212,2211,5258,5262],"class_list":["post-7677","post","type-post","status-publish","format-standard","hentry","category-d","category-medicines","tag-avatrombopag","tag-avatrombopag-side-effects","tag-avatrombopag-tablet","tag-doptelet","tag-doptelet-side-effects","tag-doptelet-tablet","tag-medicine","tag-tablets","tag-what-is-avatrombopag","tag-what-is-doptelet"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7677","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=7677"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7677\/revisions"}],"predecessor-version":[{"id":10903,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7677\/revisions\/10903"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=7677"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=7677"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=7677"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
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<\/p>\n\n\n\nChildren and young people<\/h2>\n\n\n\n
Other medicines and Doptelet<\/h2>\n\n\n\n
<\/p>\n\n\n\nPregnancy and breastfeeding<\/h2>\n\n\n\n
<\/p>\n\n\n\nDriving and using machines<\/h2>\n\n\n\n
Doptelet contains lactose<\/h2>\n\n\n\n
<\/p>\n\n\n\n3. How to take Doptelet<\/h2>\n\n\n\n
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<\/li><\/ul>\n\n\n\nIf you take more Doptelet then you should<\/h2>\n\n\n\n
If you forget to take Doptelet<\/h2>\n\n\n\n
If you stop taking Doptelet<\/h2>\n\n\n\n
<\/p>\n\n\n\n4. Possible side effects<\/h2>\n\n\n\n
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<\/li><\/ul>\n\n\n\n5. How to store the Doptelet<\/h2>\n\n\n\n
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<\/p>\n\n\n\n6. Contents of the packaging and other information<\/h2>\n\n\n\n
Content declaration<\/h2>\n\n\n\n
Tablet core: lactose monohydrate (see section 2 \u201cDoptelet contains lactose\u201d), microcrystalline cellulose [E460 (i)], crospovidone type B [E1202], colloidalanhydrous silica [E551], magnesium stearate [E470b].
Film coating: polyvinyl alcohol [E1203], talc [E553b], macrogol 3350 [E1521], titanium dioxide [E171], yellow iron oxide [E172].<\/li><\/ul>\n\n\n\nWhat the medicine looks like and the contents of the pack<\/h2>\n\n\n\n
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