{"id":7665,"date":"2021-02-26T09:05:15","date_gmt":"2021-02-26T09:05:15","guid":{"rendered":"https:\/\/zeepedia.com\/?p=7665"},"modified":"2021-05-20T06:54:59","modified_gmt":"2021-05-20T06:54:59","slug":"donepezil-actavis","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/donepezil-actavis\/","title":{"rendered":"Donepezil Actavis &#8211; Donepezil Hydrochloride uses, dose and side effects"},"content":{"rendered":"\n<p> 5 mg and 10 mg\u00a0film-coated tablets\u00a0<br>donepezil hydrochloride<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What Donepezil Actavis is and what it is used for<\/h2>\n\n\n\n<p>Donepezil Actavis belongs to a group of medicines called acetylcholinesterase inhibitors.&nbsp;It is used to treat dementia symptoms in mild to moderate&nbsp;Alzheimer&#8217;s disease.&nbsp;The drug is intended for adult patients only.<br><\/p>\n\n\n\n<p>Donepezil contained in Donepezil Actavis may also be approved for the treatment of other conditions not mentioned in this product information.&nbsp;Ask your doctor, pharmacist, or other healthcare professional if you have any further questions, and always follow their instructions.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">What you need to know before you take Donepezil Actavis<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not take Donepezil Actavis<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>if you are allergic to donepezil hydrochloride, piperidine derivatives, or any of the other ingredients of this medicine (listed in section 6).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>Treatment with Donepezil Actavis should be initiated and supervised by a physician experienced in the diagnosis and treatment of&nbsp;Alzheimer&#8217;s disease.<br><\/p>\n\n\n\n<p>Talk to your doctor or pharmacist before taking Donepezil Actavis if you<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>have ever had a&nbsp;stomach ulcer&nbsp;or ulcer in the&nbsp;duodenum&nbsp;or if you are taking medication to treat pain and&nbsp;inflammation, called&nbsp;NSAIDs.<\/li><li>have ever had a seizure.&nbsp;Donepezil may cause seizures.&nbsp;Your doctor will monitor your symptoms.<\/li><li>have had a heart condition (especially if you have an irregular heartbeat, sick-sinus syndrome, or any other condition that affects your heart rhythm), as donepezil may cause your heart to beat more slowly.<\/li><li>have&nbsp;asthma&nbsp;or another long-term lung disease.<\/li><li>have ever had liver disease.<\/li><li>have trouble emptying the bladder.<\/li><li>should undergo an operation that requires you to be anesthetized, as&nbsp;does&nbsp;one of the anesthetics may need to be adjusted.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Children and young people<\/h2>\n\n\n\n<p>Donepezil Actavis is not recommended for use in children and adolescents below 18 years.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Donepezil Actavis<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines, including medicines obtained without a prescription.&nbsp;This is especially important if you are using<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>drugs for the treatment of pain and&nbsp;inflammation&nbsp;(&nbsp;NSAIDs&nbsp;)<\/li><li>antibiotics&nbsp;such as erythromycin or rifampicin<\/li><li>medicines for fungal infections, such as&nbsp;ketoconazole&nbsp;or itraconazole<\/li><li>muscle relaxants, such as suxamethone<\/li><li>antidepressants such as&nbsp;fluoxetine<\/li><li>antispasmodics such as&nbsp;phenytoin&nbsp;or carbamazepine<\/li><li>drugs for heart disease, such as quinine, or high&nbsp;blood pressure, such as&nbsp;beta-blockers<\/li><li>other medicines that have the same effect as donepezil (like galantamine or rivastigmine) and certain medicines for diarrhea,&nbsp;Parkinson&#8217;s disease,&nbsp;and&nbsp;asthma.<\/li><li>general&nbsp;anesthesia&nbsp;(anesthesia)<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Donepezil Actavis and alcohol<\/h2>\n\n\n\n<p>You must avoid drinking alcohol while being treated with donepezil, as alcohol intake may weaken the effect of donepezil.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>If you are pregnant or breast-feeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n<p>Donepezil Actavis should not be used by breastfeeding women.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>Donepezil Actavis and the disease may impair your ability to drive and use machines.&nbsp;This medicine can cause fatigue, dizziness, and muscle cramps, especially at the beginning of treatment, and if you are affected by such symptoms, do not drive or use machines.&nbsp;You should discuss this with your doctor before performing such activities.<br><\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.&nbsp;One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or&nbsp;side effects.&nbsp;Descriptions of these effects and&nbsp;side effects&nbsp;can be found in other sections.&nbsp;Read all the information in this leaflet for guidance.&nbsp;If you are not sure, talk to your doctor or pharmacist<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Donepezil Actavis contains lactose<\/h2>\n\n\n\n<p>If you have been told by your doctor that you have an intolerance to some sugars, contact your doctor before taking this medicine.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">How to take Donepezil Actavis<\/h2>\n\n\n\n<p>Always take this medicine exactly as your doctor has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<br><\/p>\n\n\n\n<p>The strength of the tablet you are going to take may change depending on how long you have been taking the medicine and what your doctor recommends.<br><\/p>\n\n\n\n<p>Normally, you will start by taking a 5 mg tablet every night.&nbsp;After one month, the doctor may increase the&nbsp;dose&nbsp;one to 10 mg (two tablets of 5 mg or one tablet of 10 mg) every night.&nbsp;The maximum recommended&nbsp;dose&nbsp;is 10 mg every night.<br><\/p>\n\n\n\n<p>Take Donepezil Actavis by mouth with a glass of water in the evening before going to bed.<br><\/p>\n\n\n\n<p>Dose&nbsp;one does not need to be adjusted if you have kidney problems.<br><\/p>\n\n\n\n<p>For adults with mild to moderate liver disease, your doctor may need to adjust&nbsp;someone.&nbsp;There are no data in patients with severe hepatic impairment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Use for children and adolescents<\/h2>\n\n\n\n<p>Donepezil is not recommended for use in children and adolescents.<br><\/p>\n\n\n\n<p>You should always follow your doctor&#8217;s advice on how and when to take the medicine.&nbsp;Do not change the&nbsp;dose&nbsp;on your own without a&nbsp;prescription&nbsp;from a doctor.&nbsp;Do not stop taking the tablets unless your doctor tells you to.<br><\/p>\n\n\n\n<p><strong>How long to take Donepezil Actavis<\/strong><\/p>\n\n\n\n<p>Your doctor will tell you how long you should continue to take the tablets.&nbsp;You will need to see your doctor regularly to review your treatment and assess your symptoms.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you take more Donepezil Actavis then you should<\/h2>\n\n\n\n<p>Do not take more tablets than your doctor has prescribed.&nbsp;If you have ingested too much medicine or if, for example, a child has accidentally ingested the medicine, contact a doctor, hospital, or the Poison Information Center for risk assessment and advice.<\/p>\n\n\n\n<p>If you go to the hospital, take the tablets and the carton to the hospital so that the doctor knows what you have taken.<\/p>\n\n\n\n<p>In case of overdose, the following symptoms may occur: nausea, vomiting, drooling, sweating, slow&nbsp;heart rate, difficulty breathing, muscle weakness, fainting, and seizures.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to take Donepezil Actavis<\/h2>\n\n\n\n<p>Do not take a double&nbsp;dose&nbsp;to make up for a forgotten&nbsp;dose.<\/p>\n\n\n\n<p>If you forget to take a tablet, just take one tablet the next day at the usual time.&nbsp;If you forget to take the medicine for more than a week, consult your doctor before taking any more medicines.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you stop taking Donepezil Actavis<\/h2>\n\n\n\n<p>When treatment is stopped, the beneficial effects of donepezil gradually diminish.&nbsp;Do not stop taking the tablets even if you feel well unless your doctor tells you to.<br><\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects,&nbsp;although not everybody gets them.<br><\/p>\n\n\n\n<p><em><strong>Serious&nbsp;side effects&nbsp;are<\/strong><\/em><\/p>\n\n\n\n<p>You must talk to your doctor immediately if you notice these mentioned serious&nbsp;side effects.&nbsp;You may need&nbsp;urgent&nbsp;medical attention.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>liver damage e.g.&nbsp;hepatitis.&nbsp;The symptoms of&nbsp;hepatitis&nbsp;are nausea or vomiting, loss of appetite, general malaise, fever,&nbsp;itching, yellowing of the skin and eyes, and dark-colored urine (Rare: may affect up to 1 in 1,000 people)<\/li><li>stomach ulcer.&nbsp;The symptoms of&nbsp;stomach ulcers&nbsp;are abdominal pain and discomfort (indigestion) between the navel and the sternum (Uncommon: may affect up to 1 in 100 people)<\/li><li>bleeding in the stomach or intestines.&nbsp;This can lead to black stools or visible blood from the rectum (Uncommon: may affect up to 1 in 100 people)<\/li><li>uncontrolled muscle contractions (seizures) or short-term seizures with subsequent muscle twitching (Uncommon: may affect up to 1 in 100 people)<\/li><li>fever with muscle stiffness, sweating or decreased consciousness (this is a condition called malignant neuroleptic syndrome or neuroleptic malignant syndrome, very rare: may affect up to 1 in 10,000 people).<\/li><li>Muscle weakness, soreness, or pain, especially if you also feel sick, have a high fever, or dark urine.&nbsp;The symptoms can be caused by an abnormal breakdown of the muscles which can be life-threatening and lead to kidney problems (a condition called&nbsp;rhabdomyolysis&nbsp;).<br><\/li><\/ul>\n\n\n\n<p><strong>Other&nbsp;side effects&nbsp;ar<\/strong><br><\/p>\n\n\n\n<p><em>Very common (may affect more than 1 in 10 people):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>diarrhea<\/li><li>nausea<\/li><li>headache.<\/li><\/ul>\n\n\n\n<p><em>Common (may affect up to 1 in 10 people):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>common cold<\/li><li>loss of appetite<\/li><li>hallucinations, aggressive behavior, restlessness, which have disappeared with dose reduction or treatment interruption<\/li><li>dizziness, insomnia, fainting<\/li><li>vomiting, stomach upset<\/li><li>itching, rash<\/li><li>muscle cramps<\/li><li>urinary incontinence<\/li><li>fatigue, pain<\/li><li>accident.<\/li><li>abnormal dreams and nightmares<\/li><\/ul>\n\n\n\n<p><em>Uncommon (may affect up to 1 in 100 people):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>slow heart rate<\/li><li>small increases in the muscle enzyme creatine kinase in blood samples.<\/li><\/ul>\n\n\n\n<p><em>Rare (may affect up to 1 in 1,000 people):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>stiffness or uncontrolled movements, especially in the face and tongue but also in the arms and legs<\/li><li>heart disorders<\/li><\/ul>\n\n\n\n<p>If you get&nbsp;any side effects, talk to your doctor or pharmacist.&nbsp;This also applies to any&nbsp;side effects&nbsp;not mentioned in this information.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Donepezil Actavis<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<br><\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the blister\/tablet jar and outer carton.&nbsp;The expiration date is the last day of the specified month.<br><\/p>\n\n\n\n<p>No special storage instructions.<br><\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is donepezil hydrochloride.&nbsp;Each film-coated tablet contains a donepezil hydrochloride monohydrate equivalent to 5 mg or 10 mg donepezil hydrochloride.<\/li><li>The other ingredients in the tablet core are&nbsp;lactose monohydrate, corn starch, microcrystalline cellulose, magnesium stearate;&nbsp;tablet coating: polyvinyl alcohol, macrogol 3350, talc, titanium dioxide E171, and iron oxide yellow E172 (only in 10 mg tablet).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n<p>5 mg film-coated tablet is white, round, and biconvex, debossed with \u201cDZ 5\u201d on one side.<\/p>\n\n\n\n<p>10 mg film-coated tablet is a light yellow, round and biconvex, debossed with \u201cDZ 10\u201d on one side.<br><\/p>\n\n\n\n<p><em>Pack sizes<\/em>&nbsp;:<\/p>\n\n\n\n<p>Blisters: 7, 28, 30, 50, 50x 1, 56, 60, 84, 98, 100 and 120 film-coated tablets<\/p>\n\n\n\n<p>Tablet can: 28, 30, 100 and 250 film-coated tablets<br><\/p>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n<p>Actavis Group PTC.ehf<\/p>\n\n\n\n<p>Reykjav\u00edkurvegur 76-78<\/p>\n\n\n\n<p>220 Hafnarfj\u00f6r\u00f0ur<\/p>\n\n\n\n<p>Iceland<br><\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>Actavis Ltd.<\/p>\n\n\n\n<p>BLB016 Bulebel Industrial Estate, Zejtun ZTN 3000, Malta<br><\/p>\n\n\n\n<p>Actavis Group PTC ehf.<\/p>\n\n\n\n<p>Reykjavikurvegur 78, 220 Hafnarfj\u00f6r\u00f0ur, Iceland<br><\/p>\n\n\n\n<p>Balkanpharma-Dupnitsa AD<\/p>\n\n\n\n<p>3 Samokovsko Shosse Str.<\/p>\n\n\n\n<p>2600, Dupnitsa&nbsp;<br>Bulgaria<br><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Donepezil Actavis belongs to a group of medicines called acetylcholinesterase inhibitors. It is used to treat dementia symptoms in mild to moderate Alzheimer&#8217;s disease. The drug is intended for adult patients only.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2204,2200],"tags":[5289,5291,5292,5265,5267,5268,2212,2211,5290,5266],"class_list":["post-7665","post","type-post","status-publish","format-standard","hentry","category-d","category-medicines","tag-donepezil-actavis","tag-donepezil-actavis-side-effects","tag-donepezil-actavis-tablet","tag-donepezil-hydrochloride","tag-donepezil-hydrochloride-side-effects","tag-donepezil-hydrochloride-tablet","tag-medicine","tag-tablets","tag-what-is-donepezil-actavis","tag-what-is-donepezil-hydrochloride"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7665","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=7665"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7665\/revisions"}],"predecessor-version":[{"id":10915,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7665\/revisions\/10915"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=7665"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=7665"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=7665"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}