{"id":7659,"date":"2021-02-26T09:01:22","date_gmt":"2021-02-26T09:01:22","guid":{"rendered":"https:\/\/zeepedia.com\/?p=7659"},"modified":"2022-10-12T18:13:21","modified_gmt":"2022-10-12T18:13:21","slug":"doloproct","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/doloproct\/","title":{"rendered":"Doloproct &#8211; Lidocaine Hydrochloride Uses, Dose And Side Effects"},"content":{"rendered":"\n<p> 1 mg \/ g + 20 mg \/ g&nbsp;rectal&nbsp;cream&nbsp;fluocortolone&nbsp;<br>Pivalate, lidocaine hydrochloride (Anhydrous)<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"> What Doloproct is And What It Is Used For<\/h2>\n\n\n\n<p>Doloproct contains two different active substances: Fluocortolone pivalate and lidocaine hydrochloride.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance fluocortolone pivalate belongs to the group of&nbsp;corticosteroids.&nbsp;It reduces the production of substances that cause&nbsp;inflammation in the body.&nbsp;This relieves ailments such as swelling,&nbsp;itching,&nbsp;and burning.<\/li><li>The active substance lidocaine hydrochloride belongs to the group of&nbsp;local anesthetics.&nbsp;It numbs the area where it is applied.&nbsp;This relieves <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/brain-and-nerves\/pain\/\">pain<\/a> and&nbsp;itching in that area.<\/li><\/ul>\n\n\n\n<p>Doloproct is used in adults to relieve<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Nodular enlargement of blood vessels around the anus (<a href=\"https:\/\/zeepedia.com\/medical\/diseases\/hemorrhoids\/\">hemorrhoid<\/a> disease)<\/li><li>Inflammation&nbsp;of the rectal&nbsp;mucosa&nbsp;(non-infectious&nbsp;proctitis&nbsp;)<\/li><li>Inflammation&nbsp;of the upper skin layers around the anus with symptoms such as&nbsp;redness, swelling,&nbsp;itching,&nbsp;and dryness or discharge (anal&nbsp;eczema&nbsp;).<\/li><\/ul>\n\n\n\n<p>Doloproct can not remove the causes of hemorrhoid&nbsp;disease,&nbsp;inflammation&nbsp;of the rectal&nbsp;mucosa&nbsp;(non-infectious&nbsp;proctitis&nbsp;), and anus (anal&nbsp;eczema&nbsp;).<\/p>\n\n\n\n<p>You must talk to a doctor if you do not feel better or if you feel worse after 14 days<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">  What You Need To Know Before Using Doloproct<\/h2>\n\n\n\n<h3 class=\"wp-block-heading\">Do Not Use<\/h3>\n\n\n\n<ul class=\"wp-block-list\"><li>If you are allergic to fluocortolone pivalate, lidocaine hydrochloride, or any of the other ingredients of this medicine (listed in section 6).<\/li><li>If you have an&nbsp;infection&nbsp;in the skin around the anus and if you have symptoms of the following symptoms in this area:<ul><li>Skin lesions caused by&nbsp;syphilis&nbsp;or&nbsp;tuberculosis<\/li><li>Chickenpox (&nbsp;infection&nbsp;by the varicella-zoster virus)<\/li><li>Vaccination reactions<\/li><li>Genital <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/mouth-ulcer-herpes-around-the-mouth\/\">herpes<\/a> infection (genital&nbsp;herpes&nbsp;).<\/li><\/ul><\/li><\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">Warnings And Cautions<\/h3>\n\n\n\n<p>Talk to your doctor or pharmacist before using Doloproct Rectal Cream.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Be careful not to get in your eyes.&nbsp;Wash hands thoroughly after use!<\/li><li>If latex-containing products, such as condoms, are used in the same area as Doloproct, the ingredients in Doloproct may damage the latex-containing products.&nbsp;This may mean that their protection against pregnancy and sexually transmitted diseases, such as&nbsp;HIV&nbsp;infection, is lacking.&nbsp;If you have any further questions, ask your doctor or pharmacist.<\/li><li>Contact a doctor if you experience blurred vision or other visual disturbances.<\/li><\/ul>\n\n\n\n<h3 class=\"wp-block-heading\">Children And Young People<\/h3>\n\n\n\n<p>The use of the cream is not recommended for use in children and adolescents below 18 years due to insufficient data on safety and efficacy.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Other Medicines And Doloproct<\/h3>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.<\/p>\n\n\n\n<p>Some medicines may increase the effects of Doloproct and your doctor may want to monitor you closely if you are taking these medicines (eg some medicines for <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/hiv-and-aids-2\/\">HIV<\/a>: ritonavir, cobicistat).<\/p>\n\n\n\n<p>As Doloproct also contains the active substance&nbsp;lidocaine, you should tell your doctor or pharmacist if you are taking other medicines to treat irregular heartbeat (&nbsp;arrhythmia&nbsp;).<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Pregnancy And Breastfeeding<\/h3>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>Pregnancy<\/strong><\/h4>\n\n\n\n<p>To prevent any risk to your unborn baby, avoid using Doloproct when you are pregnant, especially during the first three months.<\/p>\n\n\n\n<h4 class=\"wp-block-heading\"><strong>Breast-feeding<\/strong><\/h4>\n\n\n\n<p>In general, you should not use Doloproct for an extended period of time to prevent your baby from ingesting the medicine through breast milk.&nbsp;Only use this medicine if your doctor tells you to.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Driving And Using Machines<\/h3>\n\n\n\n<p>Doloproct has no or negligible effect on the ability to drive and use machines.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\"><a href=\"https:\/\/amzn.to\/3yzavBk\" rel=\"noopener\">Doloproct<\/a> Rectal Cream contains Cetostearyl Alcohol<\/h3>\n\n\n\n<p>The ingredient cetostearyl <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/alcohol-and-drugs-risk-use-harmful-use-and-addiction\/\">alcohol<\/a> may cause local skin reactions (eg&nbsp;contact dermatitis&nbsp;).<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"250\" height=\"121\" src=\"https:\/\/zeepedia.com\/wp-content\/uploads\/2022\/10\/Doloproct-cream.jpg\" alt=\"doloproct cream\" class=\"wp-image-26195\"\/><figcaption>Doloproct Cream<\/figcaption><\/figure><\/div>\n\n\n<h2 class=\"wp-block-heading\">How To Use Doloproct<\/h2>\n\n\n\n<p>Always use this medicine exactly as your doctor has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p>The recommended&nbsp;dose&nbsp;is one fingertip unit (up to 1 g) per application.&nbsp;A fingertip unit is the amount of rectal cream that is pushed out of the tube and applied from the outermost fold of the skin to the fingertip of an adult&#8217;s index finger.&nbsp;<\/p>\n\n\n\n<p>Use Doloproct rectal cream&nbsp;<strong>twice a day, once in the morning and once in the evening.&nbsp;<\/strong>The first few days you use&nbsp;cream&nbsp;one, you can apply it three times daily.&nbsp;Later, when the symptoms have improved, once a day is often enough.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">Method of administration<\/h3>\n\n\n\n<p>Use Doloproct after emptying your bowels.<\/p>\n\n\n\n<p><em>If your doctor has told you to apply Doloproct rectal cream around the anus and the surrounding area, follow the instructions below:<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Thoroughly clean the anal area before use.<\/li><li>Apply a fingertip device (up to 1 g) Doloproct rectal cream to your fingertip.<\/li><li>Gently spread the&nbsp;cream&nbsp;on the sore or itchy anal area.&nbsp;Use your fingertip to overcome the resistance of the sphincter.<\/li><li>Wash your hands.<\/li><\/ul>\n\n\n\n<p><em>If your doctor has told you to apply a little&nbsp;cream&nbsp;deeper into the anus, follow the instructions below:<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Thoroughly clean the anal area before use.<\/li><li>Screw the applicator firmly onto the tube.<\/li><li>Insert the applicator into the anus.<\/li><li>Gently squeeze the tube so that some cream comes out of the anus.&nbsp;Slowly pull out the applicator.<\/li><li>Clean the outside of the applicator with a paper towel after each use.&nbsp;Then remove remnants of the product in the applicator with a cotton swab and clean again with a paper towel.&nbsp;Rinse the applicator in warm water for about 1 minute and then wipe the outside with a paper towel.&nbsp;Do not use the applicator if it is damaged.<\/li><li>Wash your hands.<\/li><\/ul>\n\n\n\n<p><strong>Treatment time<\/strong><\/p>\n\n\n\n<p>Doloproct should not be used for more than two weeks.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">If You Use More Doloproct Then You Should&nbsp;<\/h3>\n\n\n\n<p>There is no&nbsp;acute&nbsp;risk of poisoning if you take too much in a single-use.<\/p>\n\n\n\n<p>If you accidentally swallow Doloproct<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance&nbsp;lidocaine may&nbsp;alter cardiac function (for example slower heart rate or in extreme cases cardiac arrest)<\/li><li>You may develop symptoms related to the&nbsp;central nervous system&nbsp;(such as convulsions, shortness of breath, or in extreme cases impaired breathing).<\/li><\/ul>\n\n\n\n<p>The expected symptoms depend on&nbsp;dose&nbsp;one.&nbsp;To prevent any harmful effects after swallowing Doloproct, contact your doctor immediately.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">If You Forget To Use Doloproct<\/h3>\n\n\n\n<p>If you forget to use it, use this medicine as soon as you find it.\u00a0However, if it is almost time for\u00a0your\u00a0next\u00a0dose, skip the missed\u00a0dose.\u00a0Do not take a double\u00a0dose to make up for a forgotten\u00a0dose.<\/p>\n\n\n\n<h3 class=\"wp-block-heading\">If You Stop Using Doloproct<\/h3>\n\n\n\n<p>Do not stop treatment without consulting your doctor.<\/p>\n\n\n\n<p>If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"><strong>Doloproct Cream How To Use?<\/strong><\/h2>\n\n\n\n<p>Dose and frequency of <em>doloproct cream<\/em> supervision If not fixed otherwise by your doctor,&nbsp;<strong>insert one suppository profound into the anus two times a day, one time in the morning and after that in the evening<\/strong>. In a while, when your signs are improved, a single daily application is often satisfactory.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Doloproct Cream Side Effects<\/h2>\n\n\n\n<p>Like all medicines, <em>Doloproct cream usage<\/em> can cause&nbsp;side effects,&nbsp;although not everybody gets them.<\/p>\n\n\n\n<p>The following&nbsp;side effects&nbsp;may occur during treatment.&nbsp;They only apply to the skin in the anal area:<\/p>\n\n\n\n<p><strong>Common<\/strong>&nbsp;(may affect up to 1 in 10 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Burning in the skin<\/li><\/ul>\n\n\n\n<p><strong>Uncommon<\/strong>&nbsp;(may affect up to 1 in 100 people):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><a href=\"https:\/\/zeepedia.com\/diseases\/dry-skin-and-itching\/\">Skin irritation<\/a> (eg&nbsp;redness, dryness)<\/li><li>Allergic reactions (eg rash)<\/li><\/ul>\n\n\n\n<p><strong>Has been reported<\/strong>&nbsp;(occurs in an unknown number of users):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Dimsyn<\/li><\/ul>\n\n\n\n<p>If you <em><strong>Doloproct cream usage<\/strong><\/em> for a longer period (more than 4 weeks ), there is a risk that you may develop local skin reactions, such as<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Thinned skin (&nbsp;atrophy&nbsp;)<\/li><li>Irregular areas on the skin that look like streaks (striae)<\/li><li>Enlarged blood vessels that become visible on the skin surface (telangiectasias).<\/li><\/ul>\n\n\n\n<p><em>Reporting of side effects<\/em><\/p>\n\n\n\n<h2 class=\"wp-block-heading\"> How To Store Doloproct<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton and tube after \u201cEXP\u201d.&nbsp;The expiration date is the last day of the specified month.<\/p>\n\n\n\n<p>No special storage instructions.<\/p>\n\n\n\n<p>Cream can be used for 4 weeks after opening.<\/p>\n\n\n\n<p>Do not use this medicine if you notice that the&nbsp;cream is&nbsp;not white and opaque.<\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\"> Contents Of The Packaging And Other Information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content Declaration<\/h2>\n\n\n\n<p><strong>Doloproct rectal cream<\/strong><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substances are fluocortolone pivalate and lidocaine hydrochloride (anhydrous).<\/li><\/ul>\n\n\n\n<p>Each gram of rectal cream contains<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>1 mg fluocortolone pivalate and<\/li><li>20 mg lidocaine hydrochloride (anhydrous).<\/li><li>The other ingredients are polysorbate 60, sorbitan stearate, cetostearyl alcohol, liquid paraffin, white soft paraffin, sodium edetate, sodium dihydrogen phosphate dihydrate, disodium phosphate dodecahydrate, benzyl alcohol, and purified water.&nbsp;See section 2 rectal cream contains cetostearyl alcohol<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What The Medicine Looks Like And The Contents Of The Pack<\/h2>\n\n\n\n<p>Doloproct rectal cream is a white, opaque&nbsp;cream.<\/p>\n\n\n\n<p>The cream\u00a0one is in an aluminum tube;\u00a0an\u00a0applicator\u00a0is included.<\/p>\n\n\n\n<p>There are three pack sizes:<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>10 g<\/li><li>15 g<\/li><li>30 g<\/li><\/ul>\n\n\n\n<p>Not all pack sizes may be marketed.<\/p>\n\n\n\n<p>Doloproct is also provided as a&nbsp;suppository.<\/p>\n\n\n\n<p><strong>Manufacturer<\/strong><\/p>\n\n\n\n<p>LEO Pharma Manufacturing Italy Srl<\/p>\n\n\n\n<p>Via E. Schering 21<\/p>\n\n\n\n<p>20090 Segrate (Milano)<\/p>\n\n\n\n<p>Italy<\/p>\n\n\n\n<p><strong>This medicinal product is authorized under the European Economic Area under the names<\/strong>&nbsp;:<\/p>\n\n\n\n<p>Germany, Denmark, Iceland, Greece, Estonia, Hungary, Latvia, Slovakia, Cyprus, Malta, Austria, Lithuania, Bulgaria, Italy, and Slovenia<\/p>\n\n\n\n<p>Finland &#8211; Neoproct<\/p>\n\n\n\n<p>Portugal &#8211; Ultraproct<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Doloproct is a suppository containing a steroid (fluocortolone) and a numbing mediator (lidocaine). It is planned for the release of symptoms linked to hemorrhoids and proctitis.<\/p>\n","protected":false},"author":2,"featured_media":26195,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"yes","footnotes":""},"categories":[2204,2200],"tags":[5310,5313,5312,5305,5308,5307,2212,5309,5311,5306],"class_list":["post-7659","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-d","category-medicines","tag-doloproct","tag-doloproct-rectal-cream","tag-doloproct-side-effects","tag-lidocaine-hydrochloride","tag-lidocaine-hydrochloride-rectal-cream","tag-lidocaine-hydrochloride-side-effects","tag-medicine","tag-rectal-cream","tag-what-is-doloproct","tag-what-is-lidocaine-hydrochloride"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7659","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=7659"}],"version-history":[{"count":21,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7659\/revisions"}],"predecessor-version":[{"id":26288,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7659\/revisions\/26288"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media\/26195"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=7659"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=7659"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=7659"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}