If you think you may be pregnant or become pregnant during treatment, consult your doctor.<\/strong><\/p>\n\n\n\nYour doctor will usually suggest that you stop taking Diovan Comp before pregnancy or as soon as you know you are pregnant and instead recommend another medicine for you. Diovan Comp should not be used in early pregnancy and should not be used during the last 6 months of pregnancy as it may cause birth defects.
<\/p>\n\n\n\n
Tell your doctor if you are breast-feeding or planning to start breast-feeding.<\/strong><\/p>\n\n\n\nDiovan Comp is not recommended for breastfeeding and your doctor may choose another treatment for you if you want to breast-feed your baby, especially if your baby is newborn or born prematurely.<\/p>\n\n\n\n
Driving and using machines<\/h2>\n\n\n\n
Before driving, using tools or machines, or performing activities that require concentration, make sure you know how Diovan Comp affects you. Like many other medicines for high blood pressure, Diovan Comp can in rare cases cause dizziness and affect your ability to concentrate.
<\/p>\n\n\n\n
You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires increased vigilance. One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or side effects. Descriptions of these effects and side effects can be found in other sections. Read all the information in this leaflet for guidance. If you are not sure, talk to your doctor or pharmacist.
<\/p>\n\n\n\n
3. How to take Diovan Comp<\/h2>\n\n\n\n
Always take this medicine exactly as your doctor has told you. It will give the best results and reduce the risk of side effects. Ask your doctor or pharmacist if you are unsure. People with high blood pressure often do not feel any symptoms of this. Many feel as usual. It is therefore important that you go to your doctor’s visits as planned even if you feel good.
<\/p>\n\n\n\n
Your doctor will tell you how many Diovan Comp tablets to take. Depending on the treatment outcome, your doctor may increase or decrease the dose.<\/p>\n\n\n\n
- The recommended dose of Diovan Comp is one tablet per day.<\/li>
- Do not change the dose of one or stop treatment without consulting your doctor.<\/li>
- The drug should be taken at the same time each day, usually in the morning.<\/li>
- You can take Diovan Comp regardless of the meal.<\/li>
- Swallow Diovan Comp with a glass of water.<\/li><\/ul>\n\n\n\n
If you take more Diovan Comp then you should<\/h2>\n\n\n\n
If you have ingested too much medicine or if, for example, a child has accidentally ingested the medicine, contact a doctor, hospital, or the Poison Information Center for risk assessment and advice. If you experience severe dizziness and\/or fainting, lie down and contact a doctor immediately.<\/p>\n\n\n\n
If you forget to take Diovan Comp<\/h2>\n\n\n\n
If you forget to take a dose, take it as soon as you remember. If it is soon time for your next dose, skip the missed dose.<\/p>\n\n\n\n
Do not take a double dose to make up for a forgotten tablet.<\/p>\n\n\n\n
If you stop taking Diovan Comp<\/h2>\n\n\n\n
If you stop taking Diovan Comp, your high blood pressure may get worse. Do not stop taking your medicine unless your doctor tells you to stop.
<\/p>\n\n\n\n
If you have any further questions on the use of this product, ask your doctor or pharmacist.<\/strong><\/p>\n\n\n\n4. Possible side effects<\/h2>\n\n\n\n
Like all medicines, this medicine can cause side effects, although not everybody gets them.
<\/p>\n\n\n\n
Some side effects can be serious and require immediate medical attention:<\/strong><\/p>\n\n\n\n- You should contact your doctor immediately if you experience symptoms of angioedema, such as:
- swollen face, tongue, or throat<\/li>
- difficulty swallowing<\/li>
- hives and difficulty breathing<\/li><\/ul><\/li>
- A severe skin condition that causes rash, redness, blisters on the lips, eyes, or mouth, skin rash, fever ( toxic epidermal necrolysis )<\/li>
- Visual impairment or pain in your eyes due to high pressure (possible signs of fluid accumulation in the eye (between the choroid and retina) or acute narrow-angle glaucoma )<\/li>
- Fever, sore throat, more frequent infection is ( agranulocytosis )<\/li><\/ul>\n\n\n\n
These side effects are very rare or with no known frequency (frequency can not be calculated from the available data).
<\/p>\n\n\n\n
If you get any of these symptoms, stop taking Diovan Comp and contact your doctor immediately (see section 2 “Warnings and precautions”).<\/strong>
<\/p>\n\n\n\nThe side effects are:<\/strong>
<\/p>\n\n\n\nUncommon<\/strong> (may affect up to 1 in 100 people):<\/em><\/p>\n\n\n\n- cough<\/li>
- low blood pressure<\/li>
- dizzy<\/li>
- dehydration (with symptoms such as thirst, dryness in the mouth and tongue, rarely having to empty the bladder, dark-colored urine, dry skin)<\/li>
- pain in the muscles<\/li>
- fatigue<\/li>
- tingling and numbness<\/li>
- dimsyn<\/li>
- roaring and buzzing in the ears<\/li><\/ul>\n\n\n\n
Very rare<\/strong> (may affect up to 1 in 10,000 people):<\/em><\/p>\n\n\n\n- dizziness<\/li>
- diarrhea<\/li>
- joint pain<\/li><\/ul>\n\n\n\n
Has been reported<\/strong> (occurs in an unknown number of users):<\/em><\/p>\n\n\n\n- difficulty breathing<\/li>
- significantly reduced urine output<\/li>
- low sodium levels in the blood (which can trigger fatigue, confusion, muscle twitching, and\/or cramps in severe cases)<\/li>
- low potassium levels in the blood (sometimes with muscle weakness, muscle cramps, abnormal heart rhythm)<\/li>
- the low value of white blood cells in the blood (with symptoms such as fever, skin infections, sore throat, or cold sores due to infection, weakness)<\/li>
- elevated bilirubin levels in the blood (which in severe cases can cause yellow skin and yellow eyes)<\/li>
- elevated levels of urea nitrogen and creatinine in the blood (which may indicate impaired renal function)<\/li>
- elevated uric acid levels in the blood (which in severe cases can trigger gout )<\/li>
- syncope (fainting)<\/li><\/ul>\n\n\n\n
The following side effects have been reported with products containing valsartan or hydrochlorothiazide:<\/strong>
<\/p>\n\n\n\nValsartan<\/strong>
<\/p>\n\n\n\nUncommon<\/strong> (may affect up to 1 in 100 people):<\/em><\/p>\n\n\n\n- feeling of spinning<\/li>
- abdominal pain<\/li><\/ul>\n\n\n\n
Has been reported<\/strong> (occurs in an unknown number of users):<\/em><\/p>\n\n\n\n- blistering of the skin (signs of dermatitis, also called bullous dermatitis )<\/li>
- skin rash with or without itching along with any of the following symptoms: fever, joint pain, muscle pain, swollen lymph nodes, and\/or flu-like symptoms<\/li>
- rash, reddish-purple-red spots, fever, itching (symptoms of inflammation of the blood vessels)<\/li>
- low platelet count (sometimes with unusual bleeding or bruising)<\/li>
- high potassium levels in the blood (sometimes with muscle cramps, abnormal heart rhythm)<\/li>
- allergic reactions (with symptoms such as rash, itching, hives, difficulty breathing or difficulty swallowing, dizziness)<\/li>
- swelling mainly in the face and throat, rash, itching<\/li>
- elevated liver function values<\/li>
- decreased hemoglobin value and decreased percentage of red blood cells in the blood (both can in severe cases lead to anemia ( anemia ))<\/li>
- kidney failure<\/li>
- low levels of sodium in the blood (which can trigger fatigue, confusion, muscle twitching, and\/or cramps in severe cases)<\/li><\/ul>\n\n\n\n
Hydrochlorothiazide<\/strong><\/p>\n\n\n\nVery common<\/strong> (may affect more than 1 user in 10):<\/em><\/p>\n\n\n\n- low level of potassium in the blood<\/li>
- elevated lipid levels in the blood<\/li><\/ul>\n\n\n\n
Common<\/strong> (may affect up to 1 in 10 people):<\/em><\/p>\n\n\n\n- low level of sodium in the blood<\/li>
- low level of magnesium in the blood<\/li>
- high level of uric acid in the blood<\/li>
- itchy rash and other types of rash<\/li>
- decreased appetite<\/li>
- mild nausea and vomiting<\/li>
- dizziness, fainting when you get up<\/li>
- inability to get or maintain an erection<\/li><\/ul>\n\n\n\n
Rare<\/strong> (may affect up to 1 in 1,000 people):<\/em><\/p>\n\n\n\n- swelling and blisters on the skin (due to increased sensitivity to the sun)<\/li>
- high level of calcium in the blood<\/li>
- high blood sugar level<\/li>
- sugar in the urine<\/li>
- worsening of metabolic diabetes<\/li>
- constipation, diarrhea, stomach,h and intestinal discomfort, liver disorders that can occur with yellow skin and yellow eyes<\/li>
- irregular heartbeats<\/li>
- headache<\/li>
- sleep disorders<\/li>
- depression<\/li>
- low platelet count (sometimes with bleeding or bruising under the skin)<\/li>
- dizziness<\/li>
- tingling or numbness<\/li>
- visual disturbances<\/li><\/ul>\n\n\n\n
Very rare<\/strong> (may affect up to 1 in 10,000 people):<\/em><\/p>\n\n\n\n- inflammation of the blood vessels with symptoms such as rash, reddish-purple-red spots, fever ( vasculitis )<\/li>
- rash, itching, hives, difficulty breathing or swallowing, dizziness ( hypersensitivity reactions )<\/li>
- rash on the face, joint pain, muscle disease, fever ( cutaneous lupus erythematosus)<\/li>
- severe pain in the upper abdomen ( pancreatitis )<\/li>
- difficulty breathing with fever, cough, wheezing, shortness of breath (shortness of breath including pneumonitis and pulmonary edema )<\/li>
- pale skin, fatigue, shortness of breath, dark urine (hemolytic anemia )<\/li>
- fever, sore throat or sore mouth due to infection is ( leukopenia )<\/li>
- confusion, fatigue, muscle twitching and spasms, rapid breathing (hypochloremic alkalosis )<\/li><\/ul>\n\n\n\n
Has been reported<\/strong> (occurs in an unknown number of users):<\/em><\/p>\n\n\n\n- weakness, bruising and frequent infections ( aplastic anemia )<\/li>
- sharply reduced urine production (possible signs of kidney disease or kidney failure )<\/li>
- skin rash, redness, blisters on the lips, eyes, or mouth, flaking of the skin, fever (possible signs of erythema multiforme)<\/li>
- muscle cramps<\/li>
- fever ( pyrexia )<\/li>
- weakness ( asthenia )<\/li>
- skin and lip cancer (non-melanoma skin cancer)<\/li><\/ul>\n\n\n\n
5. How to store Diovan Comp<\/h2>\n\n\n\n- Keep out of sight and reach of children.<\/li>
- Do not use this medicine after the expiry date which is stated on the carton or blister after EXP. respectively “EXP”. The expiration date is the last day of the specified month.<\/li>
- Do not store above 30 \u00b0 C. Store in the original package. Moisture sensitive.<\/li>
- Do not use this medicine if you notice that the package is damaged or shows signs of having opened earlier.<\/li>
- The medicine should not be disposed of via wastewater or household waste. Ask your pharmacist how to dispose of medicines no longer required. These measures will help to protect the environment.<\/li><\/ul>\n\n\n\n
6. Contents of the packaging and other information<\/h2>\n\n\n\nContent declaration<\/h2>\n\n\n\n- The active substance is valsartan and hydrochlorothiazide . Each tablet contains 80 mg, 160 mg and 320 mg valsartan and 12.5 mg and 25 mg hydrochlorothiazide,respectively .<\/li>
- The core of the tablet contains microcrystalline cellulose, colloidal, anhydrous silica, crospovidone, magnesium stearate.<\/li>
- The film cover of the tablet contains hypromellose, macrogol 8000 (80 mg \/ 12.5 mg and 160 mg \/ 12.5 mg only), macrogol 4000 (160 mg \/ 25 mg, 320 mg \/ 12.5 mg and 320 mg \/ 25 mg only) , talc, red iron oxide (E 172, not 320 mg \/ 25 mg), yellow iron oxide (E 172, 80 mg \/ 12.5 mg only, 160 mg \/ 25 mg and 320 mg \/ 25 mg), black iron oxide (E 172 , only 160 mg \/ 25 mg and 320 mg \/ 12.5 mg), titanium dioxide (E 171).<\/li><\/ul>\n\n\n\n
What the medicine looks like and the contents of the pack<\/h2>\n\n\n\n
Diovan Comp 80 mg \/ 12.5 mg film-coated tablets are bright orange, oval tablets, marked with \u201cHGH\u201d on one side and \u201cCG\u201d on the other side.<\/p>\n\n\n\n
Diovan Comp 160 mg \/ 12.5 mg film-coated tablets are dark red, oval tablets, marked with \u201cHHH\u201d on one side and \u201cCG\u201d on the other side.<\/p>\n\n\n\n
Diovan Comp 160 mg \/ 25 mg film-coated tablets are brown, oval tablets, marked with \u201cHXH\u201d on one side and \u201cNVR\u201d on the other side.<\/p>\n\n\n\n
Diovan Comp 320 mg \/ 12.5 mg film-coated tablets are pink, oval tablets with beveled edges, marked with \u201cNVR\u201d on one side and \u201cHIL\u201d on the other side.<\/p>\n\n\n\n
Diovan Comp 320 mg \/ 25 mg film-coated tablets are yellow, oval tablets with beveled edges, marked with \u201cNVR\u201d on one side and \u201cCTI\u201d on the other side.
<\/p>\n\n\n\n
The tablets are supplied in blister packs of 7 pcs (Diovan Comp 320 mg \/ 12.5 mg and 320 mg \/ 25 mg only), 14 pcs, 28 pcs as a calendar pack , 30 pcs (Diovan Comp 80 mg \/ 12.5 mg only), 56 pcs, 98 pcs as calendar packaging or 280 pcs tablets.<\/p>\n\n\n\n
Perforated unit dose blister pack of 56×1, 98×1, or 280×1 tablets is also available.
<\/p>\n\n\n\n
Not all pack sizes may be marketed.<\/p>\n\n\n\n
Marketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n
Novartis Sverige AB,<\/p>\n\n\n\n
Box 1218<\/p>\n\n\n\n
164 28 Kista<\/p>\n\n\n\n
Phone: 08-732 32 00
<\/p>\n","protected":false},"excerpt":{"rendered":"
Diovan Comp film-coated tablets contain two active substances, valsartan and hydrochlorothiazide. Both substances help control high blood pressure.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2204,2200],"tags":[5510,5512,5513,3664,3666,4301,4124,4126,5514,5511,4300],"class_list":["post-7543","post","type-post","status-publish","format-standard","hentry","category-d","category-medicines","tag-diovan-comp","tag-diovan-comp-side-effects","tag-diovan-comp-tablet","tag-hydrochlorothiazide","tag-hydrochlorothiazide-side-effects","tag-hydrochlorothiazide-tablet","tag-valsartan","tag-valsartan-side-effects","tag-valsartan-tablet","tag-what-is-diovan-comp","tag-what-is-hydrochlorothiazide"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7543","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=7543"}],"version-history":[{"count":3,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7543\/revisions"}],"predecessor-version":[{"id":10978,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7543\/revisions\/10978"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=7543"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=7543"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=7543"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}