{"id":7478,"date":"2021-02-23T09:24:01","date_gmt":"2021-02-23T09:24:01","guid":{"rendered":"https:\/\/zeepedia.com\/?p=7478"},"modified":"2021-05-24T11:23:11","modified_gmt":"2021-05-24T11:23:11","slug":"differin","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/differin\/","title":{"rendered":"Differin &#8211; Adapalene uses, dose and side effects"},"content":{"rendered":"\n<p> 1 mg \/ g\u00a0gel\u00a0<br>adapalene<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What Differin is and what it is used for<\/h2>\n\n\n\n<p>Differin inhibits&nbsp;inflammation&nbsp;in&nbsp;acne&nbsp;(pimples, blackheads, and pimples) and normalizes the formation of cells in the skin around the sebaceous glands so that the sebaceous glands are not clogged.<br><\/p>\n\n\n\n<p>The adapalene contained in Differin may also be approved for the treatment of other diseases not mentioned in this product information.&nbsp;Ask your doctor, pharmacist, or other healthcare professional if you have any further questions, and always follow their instructions.<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">2. What you need to know before you use Differin<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do not use Differin<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>If you are pregnant<\/li><li>If you are planning to become pregnant<\/li><li>If you are allergic to adapalene or any of the other ingredients of this medicine (listed in section 6).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings and cautions<\/h2>\n\n\n\n<p>When&nbsp;hypersensitivity reaction&nbsp;or severe irritation occurs, treatment should be discontinued.<br><\/p>\n\n\n\n<p>Differin must not come into contact with the eyes, mouth, nostrils, or mucous membranes.&nbsp;If the product gets into the eye, rinse immediately with warm water.&nbsp;Differin should not be used on damaged skin (wounds and abrasions), sunburned or&nbsp;eczematous&nbsp;skin, in case of rash around the mouth, or the skin disease&nbsp;rosacea.&nbsp;Differin should also not be used for severe&nbsp;acne&nbsp;on large parts of the body.<br><\/p>\n\n\n\n<p>When treating with Differin, tanning, even in tanning beds, should be avoided.&nbsp;Sunscreen products and covering clothing over treated areas should be used when exposure to sunlight is unavoidable.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other medicines and Differin<\/h2>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking or have recently taken any other medicines, including medicines obtained without a prescription.<br><\/p>\n\n\n\n<p>Differin may be irritating to the skin, and it is, therefore, possible that concomitant use of dehydrating cleansers or other skin irritants (eg containing perfume or alcohol) may irritate.<br><\/p>\n\n\n\n<p>Acne preparations with another mechanism of action, e.g.&nbsp;benzoyl peroxide, can be used if applied in the morning and Differin in the evening.<br><\/p>\n\n\n\n<p>Topical&nbsp;preparations with a similar mechanism of action should not be used during the treatment period.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy and breastfeeding<\/h2>\n\n\n\n<p>DO NOT use Differin if you are pregnant or planning to become pregnant.&nbsp;Your doctor can give you more information.<br><\/p>\n\n\n\n<p>Differin can be used during breast-feeding.&nbsp;To avoid exposure of the baby, you should avoid applying Differin to your breast.<br><\/p>\n\n\n\n<p>Ask your doctor or pharmacist for advice before taking any medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving and using machines<\/h2>\n\n\n\n<p>No effects on the ability to drive and use machines have been observed.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Differin contains excipients<\/h2>\n\n\n\n<p><strong>Differin contains<\/strong>&nbsp;propylene glycol, which can cause skin irritation.<\/p>\n\n\n\n<p>Differin contains&nbsp;methyl parahydroxybenzoate (E218)&nbsp;as a&nbsp;preservative, which may cause an&nbsp;allergic reaction&nbsp;(possibly delayed).<br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. How to use Differin<\/h2>\n\n\n\n<p>Always use this medicine exactly as your doctor or pharmacist has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<br><\/p>\n\n\n\n<p>After washing the skin, apply for the medicine in a thin layer on the affected skin areas once a day at bedtime.<br><\/p>\n\n\n\n<p>The skin should be dry before applying for the medicine.<br><\/p>\n\n\n\n<p>The treatment can cause skin irritation, e.g.&nbsp;scaling and&nbsp;redness, it may then be necessary to use Differin less often or to stop for a while.<br><\/p>\n\n\n\n<p>If Differin is applied in excess, neither faster nor better results are achieved, and pronounced&nbsp;redness, flaking or discomfort may occur.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Use for children and adolescents<\/h2>\n\n\n\n<p>Differin is only intended for the treatment of adults and adolescents aged 12 years and up.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you use more Differin than you should<\/h2>\n\n\n\n<p>If you have ingested too much medicine or if e.g.&nbsp;If a child has inadvertently ingested the medicine, contact a doctor, hospital, or the Poison Information Center for risk assessment and advice.<br><\/p>\n\n\n\n<p>Differin should be used exclusively on the skin and should not be taken.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If you forget to use Differin<\/h2>\n\n\n\n<p>Do not take a double&nbsp;dose&nbsp;to make up for a forgotten&nbsp;dose&nbsp;.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible side effects<\/h2>\n\n\n\n<p>Like all medicines, Differin can cause&nbsp;side effects,&nbsp;although not everybody gets them.<br><\/p>\n\n\n\n<p>Contact a doctor immediately if you notice any of the following symptoms &#8211; you may need&nbsp;urgent&nbsp;medical treatment: Swelling of the face, lips or throat that makes it difficult to swallow or breathe, skin rash,&nbsp;itching&nbsp;,&nbsp;hives&nbsp;and dizziness.&nbsp;This may be a sign of&nbsp;angioedema&nbsp;or a severe&nbsp;allergic reaction&nbsp;(no known frequency, can not be calculated from the available data).<br><\/p>\n\n\n\n<p>Differin may cause the following&nbsp;side effects&nbsp;in the area in which it was applied:<br><\/p>\n\n\n\n<p><strong>Common&nbsp;adverse&nbsp;s<\/strong>&nbsp;(occurring in less than 1 in 10):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>dry skin<\/li><li>skin irritation<\/li><li>burning sensation in the skin<\/li><li>redness&nbsp;of the skin (&nbsp;erythema&nbsp;)<\/li><\/ul>\n\n\n\n<p><strong>Less common&nbsp;side effects&nbsp;are<\/strong>&nbsp;(occurring in less than 1 in 100):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>local skin rash (&nbsp;contact dermatitis&nbsp;)<\/li><li>discomfort in the skin<\/li><li>solsveda<\/li><li>itching&nbsp;of the skin (&nbsp;pruritus&nbsp;)<\/li><li>exfoliation of the skin (exfoliation)<\/li><li>acne<\/li><\/ul>\n\n\n\n<p><strong>No known frequency<\/strong>&nbsp;(cannot be calculated from the available data):<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>allergic contact reaction<\/li><li>pain in skin<\/li><li>swelling of the skin<\/li><li>irritation of eyelids<\/li><li>redness&nbsp;of eyelids (&nbsp;erythema&nbsp;)<\/li><li>itching&nbsp;of the eyelids (&nbsp;pruritus&nbsp;)<\/li><li>swelling of eyelids<\/li><li>dark discoloration of light skin<\/li><li>light discoloration of dark skin<\/li><li>burn at the application site<\/li><\/ul>\n\n\n\n<p><em>Burns at the application site (mainly superficial burns but also second degree or severe burns) have been reported.<\/em><br><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How to store Differin<\/h2>\n\n\n\n<p>Keep this medicine out of the sight and reach of children.<br><\/p>\n\n\n\n<p>Do not use this medicine after the expiry date which is stated on the carton.&nbsp;The expiration date is the last day of the specified month.<br><\/p>\n\n\n\n<p>Do not store above 25 \u00b0 C.&nbsp;Store in a cold place.&nbsp;Do not freeze.<br><\/p>\n\n\n\n<p>Medicines should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents of the packaging and other information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is adapalene 1 mg \/ g.<\/li><li>The other ingredients are carbomer, propylene glycol, Poloxamer 182, disodium edetate, methyl parahydroxybenzoate (&nbsp;preservative&nbsp;E 218), phenoxyethanol (&nbsp;preservative&nbsp;), sodium hydroxide and purified water.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What the medicine looks like and contents of the pack<\/h2>\n\n\n\n<p>30 g and 60 g.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Manufacturer<\/h2>\n\n\n\n<p>Galderma Laboratories<\/p>\n\n\n\n<p>ZI Montd\u00e9sir<\/p>\n\n\n\n<p>74540 Alby-sur-Ch\u00e9ran<\/p>\n\n\n\n<p>France<\/p>\n\n\n\n<p><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Differin inhibits inflammation in acne (pimples, blackheads, and pimples) and normalizes the formation of cells in the skin around the sebaceous glands so that the sebaceous glands are not clogged.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2204,2200],"tags":[4077,5626,4079,5627,5630,5629,3558,2212,5628],"class_list":["post-7478","post","type-post","status-publish","format-standard","hentry","category-d","category-medicines","tag-adapalene","tag-adapalene-gel","tag-adapalene-side-effects","tag-differin","tag-differin-gel","tag-differin-side-effects","tag-gel","tag-medicine","tag-what-is-differin"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7478","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=7478"}],"version-history":[{"count":3,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7478\/revisions"}],"predecessor-version":[{"id":11015,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7478\/revisions\/11015"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=7478"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=7478"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=7478"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}