100 micrograms \/ ml concentrate for solution for infusion dexmedetomidine<\/p>\n\n\n\n
Dexdor contains an active substance called dexmedetomidine which belongs to a group of medicines called sedatives. It is used to provide sedation (a state of calm, drowsiness, or sleep) in adult patients in intensive care units in hospitals or awake sedation during diagnostic or surgical procedures.
<\/p>\n\n\n\n
You should not get Dexdor
<\/p>\n\n\n\n
– if you are allergic to dexmedetomidine or any of the other ingredients of this medicine (listed in section 6).<\/p>\n\n\n\n
– if you have any disturbances in your heart rhythm (Atrioventricular block grade II or III, unless you are pacemaker-treated).<\/p>\n\n\n\n
– if you have very low blood pressure that does not respond to treatment.<\/p>\n\n\n\n
– if you have recently had a stroke or any other serious condition that affects blood flow to the brain.<\/p>\n\n\n\n
Before you take this medicine, talk to your doctor or nurse if any of the following apply as Dexdor should be used with caution:
<\/p>\n\n\n\n
– if you have an unusually low heart rate (either due to illness or due to good physical condition) as it may increase the risk of cardiac arrest<\/p>\n\n\n\n
– if you have low blood pressure<\/p>\n\n\n\n
– if you have low blood volume, for example after bleeding<\/p>\n\n\n\n
– if you have some heart problems<\/p>\n\n\n\n
– if you are older<\/p>\n\n\n\n
– if you have a neurological injury (for example, head injury, spinal cord injury, or stroke )<\/p>\n\n\n\n
– if you have severe liver disease<\/p>\n\n\n\n
– if you have ever had a severe fever after taking any medicine, especially in connection with anesthesia ( anesthesia )<\/p>\n\n\n\n
Tell your doctor or nurse if you are taking, have recently taken, or might take any other medicines.
<\/p>\n\n\n\n
The following medicines may increase the effect of Dexdor:
<\/p>\n\n\n\n
– medicines that help you sleep or lead to sedation (eg midazolam, propofol)<\/p>\n\n\n\n
– strong painkillers (eg opioids such as morphine, codeine )<\/p>\n\n\n\n
– anesthetic drugs (eg sevoflurane, isoflurane)
<\/p>\n\n\n\n
If you are taking medicines that lower your blood pressure and your heart rate, concomitant use of Dexdor may increase these effects. Dexdor should not be used with medicines that, in connection with anesthesia, provide temporary muscle relaxation (muscle relaxants).<\/p>\n\n\n\n
Dexdor should not be used during pregnancy or breast-feeding unless clearly necessary.<\/p>\n\n\n\n
Talk to your doctor before using this medicine.<\/p>\n\n\n\n
Dexdor has a major impact on the ability to drive and use machines. Once you have received Dexdor, you must not drive, use machines, or work in dangerous situations until the effect is completely gone. Ask your doctor when you can start these activities again.
<\/p>\n\n\n\n
Dexdor contains less than 1 mmol sodium (23 mg) per ml, ie essentially ‘sodium-free’.<\/p>\n\n\n\n
<\/p>\n\n\n\n
Intensive care in hospitals<\/strong><\/p>\n\n\n\n Dexdor is given to you by a doctor or nurse in an intensive care unit of a hospital. Vigilant sedation<\/strong><\/p>\n\n\n\n Dexdor is administered to you by a doctor or nurse before and\/or during diagnostic or surgical procedures that require sedation, ie awake sedation. Your doctor will determine the appropriate dose for you. The amount of Dexdor depends on your age, body weight, general health, needed sedation level, and how you respond to treatment. Your doctor may change your dose if necessary and will monitor your heart and blood pressure during treatment. Dexdor is diluted and given to you as an infusion (drip) into a blood vessel. After sedation\/awakening<\/strong><\/p>\n\n\n\n If you have been given too much Dexdor, your blood pressure may increase or decrease, your heart rate may drop, you may breathe more slowly and you may feel drowsy. Your doctor will know how to treat you based on your condition.<\/p>\n\n\n\n If you have any further questions on the use of this product, ask your doctor.<\/p>\n\n\n\n Like all medicines, this medicine can cause side effects, although not everybody gets them. Very common<\/strong> (affects more than 1 patient in 10)<\/p>\n\n\n\n – low heart rate<\/p>\n\n\n\n – low or high blood pressure<\/p>\n\n\n\n change in breathing patterns or pauses in breathing. Common<\/strong> (affects more than 1 patient in 100 but less than 1 in 10 patients)<\/p>\n\n\n\n – chest pain or heart attack<\/p>\n\n\n\n – high heart rate<\/p>\n\n\n\n low or high blood sugar<\/p>\n\n\n\n nausea, vomiting, or dry mouth<\/p>\n\n\n\n restlessness<\/p>\n\n\n\n high body temperature<\/p>\n\n\n\n symptoms after stopping the medicine. Uncommon<\/strong> (affects more than 1 in 1,000 patients but less than 1 in 100 patients)<\/p>\n\n\n\n – impaired heart function, cardiac arrest<\/p>\n\n\n\n – swollen abdomen<\/p>\n\n\n\n – thirst<\/p>\n\n\n\n – a condition when there is too much acid in the body (so-called metabolic acidosis )<\/p>\n\n\n\n – low albumin levels in the blood<\/p>\n\n\n\n – shortness of breath<\/p>\n\n\n\n – hallucinations<\/p>\n\n\n\n – that the drug is not effective enough. Has been reported (occurs in an unknown number of users):<\/em> <\/p>\n\n\n\n need to empty the bladder more often than usual. Reporting of side effects ar<\/strong><\/p>\n\n\n\n If you get any side effects, talk to your doctor or nurse. This also applies to side effects that are not mentioned in this information. You can also report side effects directly via the national reporting system listed in Appendix V. By reporting side effects, you can help increase drug safety information.<\/p>\n\n\n\n Keep this medicine out of the sight and reach of children. Do not use this medicine after the expiry date which is stated on the label after \u201cEXP\u201d and the carton after \u201cEXP\u201d. No special temperature instructions. Store the ampoules or vials in the outer carton. Sensitive to light.<\/p>\n\n\n\n – The active substance is dexmedetomidine. One ml of concentrate contains dexmedetomidine hydrochloride equivalent to 100 micrograms dexmedetomidine.<\/p>\n\n\n\n – The other ingredients are sodium chloride and water for injections. One 2 ml ampoule contains 200 micrograms dexmedetomidine (as hydrochloride).<\/p>\n\n\n\n One 2 ml vial contains 200 micrograms of dexmedetomidine (as hydrochloride).<\/p>\n\n\n\n One 4 ml vial contains 400 micrograms of dexmedetomidine (as hydrochloride).<\/p>\n\n\n\n One 10 ml vial contains 1000 micrograms of dexmedetomidine (as hydrochloride). The concentration of the solution after dilution should be either 4 micrograms\/ml or 8 micrograms\/ml.<\/p>\n\n\n\n Concentrate for solution for infusion (sterile concentrate).<\/p>\n\n\n\n The concentrate is a clear, colorless solution. Packaging:<\/strong><\/p>\n\n\n\n 2 ml ampoule is made of glass<\/p>\n\n\n\n 2, 5, or 10 ml glass vials Pack sizes:<\/strong><\/p>\n\n\n\n 5 x 2 ml ampoule is<\/p>\n\n\n\n 25 x 2 ml ampoule is<\/p>\n\n\n\n 5 x 2 ml vials<\/p>\n\n\n\n 4 x 4 ml vials<\/p>\n\n\n\n 4 x 10 ml vials Not all pack sizes may be marketed.<\/p>\n\n\n\n Marketing Authorisation Holder:<\/strong><\/p>\n\n\n\n Orion Corporation<\/p>\n\n\n\n Orionintie 1<\/p>\n\n\n\n FI-02200 Espoo<\/p>\n\n\n\n Finland Manufacturer:<\/strong><\/p>\n\n\n\n Orion Corporation Orion Pharma<\/p>\n\n\n\n Orionintie 1<\/p>\n\n\n\n FI-02200 Espoo<\/p>\n\n\n\n Finland For any information about this medicine, please contact the local representative of the Marketing Authorization Holder<\/p>\n\n\n\n Dexdor contains an active substance called dexmedetomidine which belongs to a group of medicines called sedatives. It is used to provide sedation (a state of calm, drowsiness, or sleep) in adult patients in intensive care units in hospitals or awake sedation during diagnostic or surgical procedures.<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"","footnotes":""},"categories":[2204,2200],"tags":[5708,5712,5710,5711,5687,5690,5689,5691,5709,5688],"class_list":["post-7451","post","type-post","status-publish","format-standard","hentry","category-d","category-medicines","tag-dexdor","tag-dexdor-dose","tag-dexdor-side-effects","tag-dexdor-uses","tag-dexmedetomidine","tag-dexmedetomidine-dose","tag-dexmedetomidine-side-effects","tag-dexmedetomidine-uses","tag-what-is-dexdor","tag-what-is-dexmedetomidine"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7451","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=7451"}],"version-history":[{"count":4,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7451\/revisions"}],"predecessor-version":[{"id":11043,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7451\/revisions\/11043"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=7451"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=7451"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=7451"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}
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<\/p>\n\n\n\nIf you use more Dexdor than you should <\/h2>\n\n\n\n
4. Possible side effects<\/h2>\n\n\n\n
<\/p>\n\n\n\n
<\/p>\n\n\n\n
<\/p>\n\n\n\n
<\/p>\n\n\n\n
<\/p>\n\n\n\n5. How to store Dexdor<\/h2>\n\n\n\n
<\/p>\n\n\n\n
<\/p>\n\n\n\n6. Contents of the packaging and other information<\/h2>\n\n\n\n
Content declaration<\/h2>\n\n\n\n
<\/p>\n\n\n\n
<\/p>\n\n\n\nWhat the medicine looks like and the contents of the pack<\/h2>\n\n\n\n
<\/p>\n\n\n\n
<\/p>\n\n\n\n
<\/p>\n\n\n\nMarketing Authorization Holder and Manufacturer<\/h2>\n\n\n\n
<\/p>\n\n\n\n
<\/p>\n\n\n\nBelgium \/ Belgique \/ Belgien<\/strong>Luxembourg \/ Luxemburg<\/strong>Orion Pharma BVBA \/ SPRLTel: +32 (0) 15 64 10 20<\/td>
<\/td><\/tr>The Netherlands<\/strong>Orion Pharma BVBA \/ SPRLTel: +32 (0) 15 64 10 20
<\/td>Denmark<\/strong>Orion Pharma A \/ STel: +45 8614 00 00
<\/td><\/tr> Czech Republic<\/strong>Orion Pharma sroTel: +420 234 703 305<\/td> Eesti<\/strong>Orion Pharma Eesti O\u00fc Tel: +372 6 644 550
<\/td><\/tr>Germany<\/strong> Austria<\/strong>Orion Pharma GmbHTel: + 49 40 899 6890<\/td> Spain<\/strong>Orion Pharma SLTel: + 34 91 599 86 01
<\/td><\/tr>Greece<\/strong>Orion Pharma Hellas ME\u03a0.E:\u0397\u03bb: + 30 210 980 3355<\/td> Ireland<\/strong>Orion Pharma (Ireland) Ltd.Tel: + 353 1 428 7777
<\/td><\/tr>France<\/strong>Center for Pharmaceutical SpecialtiesTel: + 33 (0) 1 47 04 80 46
<\/td>Italy<\/strong>Orion Pharma SrlTel: + 39 02 67876111<\/td><\/tr> Iceland<\/strong>Vistor hf.Phone: +354 535 7000
<\/td>Latvia<\/strong>Orion Corporation in LatviaTel: + 371 6745 5569
<\/td><\/tr>\u039a\u03cd\u03c0\u03c1\u03bf\u03c2<\/strong>Lifepharma (ZAM) Ltd.:\u0397\u03bb .: +357 22347440<\/td> Hungary<\/strong>Orion Pharma Kft.<\/strong>Tel .: +36 1 239 9095
<\/td><\/tr>Lithuania<\/strong>UAB Orion PharmaTel: +370 5 276 9499<\/td> Poland<\/strong>Orion Pharma Poland Sp. ZooTel .: + 48 22 8 333 177
<\/td><\/tr>Norway<\/strong>Orion Pharma ASTel: + 47 4000 4210<\/td> Slovenia<\/strong>Orion Pharma doo<\/strong>
Tel: +386 (0) 1 600 8015
<\/td><\/tr>Portugal<\/strong>Orionfin Unipessoal LdaTel: + 351 21 154 68 20 <\/td> Finland \/ Finland<\/strong>Orion CorporationPuh \/ Tel: + 358 10 4261
<\/td><\/tr>Bulgaria<\/strong>Orion CorporationTel: + 358 10 4261
<\/td>Croatia<\/strong>PHOENIX Pharmacy dooTel: +385 1 6370450
<\/td><\/tr>Malta<\/strong>Orion CorporationTel: + 358 10 4261
<\/td>Romania<\/strong>Orion CorporationTel: + 358 10 4261
<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n
<\/p>\n","protected":false},"excerpt":{"rendered":"