{"id":7415,"date":"2021-02-22T06:46:11","date_gmt":"2021-02-22T06:46:11","guid":{"rendered":"https:\/\/zeepedia.com\/?p=7415"},"modified":"2022-11-26T11:54:50","modified_gmt":"2022-11-26T11:54:50","slug":"dexafree","status":"publish","type":"post","link":"https:\/\/zeepedia.com\/medical\/medicines\/dexafree\/","title":{"rendered":"Dexafree &#8211; Dexamethasone Phosphate Uses, Dose, And Side Effects"},"content":{"rendered":"\n<p><strong>Dexafree 1 mg\/ml\u00a0Eye Drops, Solution in\u00a0single-dose container\u00a0Dexamethasone\u00a0Phosphate<\/strong><\/p>\n\n\n\n<h2 class=\"wp-block-heading\">1. What Dexafree Is And What It Is Used For<\/h2>\n\n\n\n<p>Dexafree is&nbsp;a disposable&nbsp;eye drop&nbsp;that contains a substance called dexamethasone.&nbsp;The substance is a&nbsp;corticosteroid&nbsp;that inhibits inflammatory symptoms.<\/p>\n\n\n\n<p><strong>Dexafree eye drops<\/strong> are used to treat\u00a0<a href=\"https:\/\/zeepedia.com\/diseases\/eye-inflammation-in-children\/\">inflammation\u00a0in the eye<\/a>\u00a0(s).\u00a0The eye should not be infected (red eyes,\u00a0secretions, tear flow).\u00a0Upon\u00a0infection\u00a0should specific treatment for\u00a0the infection\u00a0a prescribed (see section 2).<\/p>\n\n\n\n<p>Dexamethasone contained in Dexafree may also be approved for the treatment of other conditions not mentioned in this product information.&nbsp;Ask your doctor, pharmacist, or another healthcare professional if you have any further questions, and always follow their instructions.<\/p>\n\n\n<div class=\"wp-block-image\">\n<figure class=\"aligncenter size-medium\"><a href=\"https:\/\/amzn.to\/3ihoXbV\" rel=\"noopener\"><img loading=\"lazy\" decoding=\"async\" width=\"174\" height=\"300\" src=\"https:\/\/zeepedia.com\/wp-content\/uploads\/2022\/11\/Dexafree-174x300.jpg\" alt=\"Dexafree\" class=\"wp-image-36238\" srcset=\"https:\/\/zeepedia.com\/medical\/wp-content\/uploads\/2022\/11\/Dexafree-174x300.jpg 174w, https:\/\/zeepedia.com\/medical\/wp-content\/uploads\/2022\/11\/Dexafree.jpg 333w\" sizes=\"auto, (max-width: 174px) 100vw, 174px\" \/><\/a><figcaption>Dexafree Eye Drops<\/figcaption><\/figure><\/div>\n\n\n<h2 class=\"wp-block-heading\">2. What You Need To Know Before Using Dexafree<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Do Not Use Dexafree<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>If you have an&nbsp;<strong>eye infection<\/strong>&nbsp;that can be caused by a&nbsp;bacterial&nbsp;(&nbsp;acute&nbsp;purulent&nbsp;infection&nbsp;), a fungus, a&nbsp;virus&nbsp;(<a href=\"https:\/\/zeepedia.com\/medical\/diseases\/mouth-ulcer-herpes-around-the-mouth\/\">herpes<\/a> virus, vaccinia virus,&nbsp;<em>varicella zona<\/em>&nbsp;&#8211;&nbsp;viruses&nbsp;), or an&nbsp;amoeba,<\/li><li>If you have&nbsp;<strong>corneal damage<\/strong>&nbsp;(holes, wounds, or injuries due to incomplete healing),<\/li><li>If you have&nbsp;<strong>ocular&nbsp;hypertension&nbsp;(increased pressure in the eye)<\/strong>&nbsp;which is known to be caused by neurosteroids (a type of&nbsp;corticosteroid&nbsp;),<\/li><li>If you are&nbsp;<strong>allergic&nbsp;to dexamethasone<\/strong>&nbsp;or any of the other ingredients of <span style=\"text-decoration: underline;\">Dexafree eye drops<\/span> (listed in section 6).<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Warnings And Cautions<\/h2>\n\n\n\n<p>Talk to your doctor or pharmacist before using Dexafree.<\/p>\n\n\n\n<p><em>DO NOT INJECT OR SWALLOW<\/em><\/p>\n\n\n\n<p>Avoid contact between the drip tip and the eye or eyelid.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Close eye checks are always required<\/strong>\u00a0when using it and especially:<ul><li>In children and the elderly.\u00a0More frequent eye examinations are recommended<\/li><li>If you have an\u00a0eye infection.\u00a0Only use Dexafree if\u00a0the infection is\u00a0treated with\u00a0antibiotics or if you have corneal ulcers.\u00a0Do not use topical dexamethasone treatment or Dexafree, unless\u00a0inflammation\u00a0is the main cause of delayed wound healing.<\/li><li>If you have increased pressure in the eye.\u00a0If you have already experienced\u00a0side effects\u00a0from treatment with local\u00a0steroids\u00a0that resulted in increased pressure in the eye, you are at risk of developing increased pressure in the eye if you are treated with Dexafree.<\/li><li>If you have\u00a0glaucoma\u00a0(\u00a0glaucoma\u00a0).<\/li><\/ul><\/li><\/ul>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Children:\u00a0<\/strong>continuous\u00a0long-term treatment should be avoided.<\/li><li><strong>Severe allergic\u00a0conjunctivitis\u00a0(\u00a0inflammation\u00a0of the\u00a0conjunctiva of the eye\u00a0)<\/strong>: if you have severe allergic\u00a0conjunctivitis\u00a0that does not respond to standard treatment, use Dexafree for only a short time.<\/li><li><strong><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/diabetes-type-1\/\">Diabetes<\/a>: <\/strong>If\u00a0you are diabetic, tell your ophthalmologist.<\/li><li><strong>Red-eye:<\/strong>\u00a0if you have red-eye that has not been diagnosed, do not use Dexafree.<\/li><li><strong>Contact lenses:<\/strong>\u00a0Avoid wearing contact lenses during treatment with it.<\/li><\/ul>\n\n\n\n<p>Talk to your doctor if you experience swelling and weight gain around the torso and face, as these are usually the first signs of a syndrome called Cushing&#8217;s syndrome.&nbsp;The impaired adrenal function may develop after discontinuation of long-term or intensive treatment with Dexafree.&nbsp;These risks are particularly important for children and patients treated with medicines called ritonavir or cobicistat.&nbsp;Therefore, talk to your doctor before stopping treatment yourself.<\/p>\n\n\n\n<p>Contact a doctor if you experience blurred vision or other visual disturbances.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Other Medicines And Dexafree<\/h2>\n\n\n\n<p>If you are using any other medicine to be applied to the eye, wait 15 minutes between each preparation.<\/p>\n\n\n\n<p>Tell your doctor if you are taking ritonavir or cobicistat, as this may increase the amount of dexamethasone in your blood.<\/p>\n\n\n\n<p>Precipitation of calcium phosphate on the surface of the cornea has been observed during concomitant treatment with local&nbsp;steroids&nbsp;and&nbsp;beta-blockers.<\/p>\n\n\n\n<p>Tell your doctor or pharmacist if you are taking, have recently taken, or might take any other medicines.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Pregnancy And Breastfeeding<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>There is insufficient information on the use of Dexafree during pregnancy to evaluate the potential&nbsp;side effects. Therefore, the use of Dexafree during pregnancy is not recommended.<\/li><li>It is not known whether Dexafree is excreted in human milk.&nbsp;However, the total&nbsp;dose&nbsp;of dexamethasone is small.&nbsp;Therefore, Dexafree can be used during breastfeeding.<\/li><\/ul>\n\n\n\n<p>If you are pregnant or breastfeeding, think you may be pregnant, or are planning to have a baby, ask your doctor or pharmacist for advice before taking this medicine.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Driving And Using Machines<\/h2>\n\n\n\n<p>As with all&nbsp;eye drops, transient blurred vision or other visual disturbances may affect the ability to drive or use machines.&nbsp;Do not drive or use machines until you have regained normal vision.<\/p>\n\n\n\n<p>You are responsible for assessing whether you are fit to drive a motor vehicle or perform work that requires sharpened attention.&nbsp;One of the factors that can affect your ability in these respects is the use of drugs due to their effects and\/or&nbsp;side effects.<\/p>\n\n\n\n<p>Descriptions of these effects and&nbsp;side effects&nbsp;can be found in other sections.&nbsp;Read all the information in this leaflet for guidance.&nbsp;If you are not sure, talk to your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">Dexafree Contains Phosphate<\/h2>\n\n\n\n<p>This medicine contains 80 micrograms of&nbsp;phosphate&nbsp;per drop.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">3. Dexafree How To Use<\/h2>\n\n\n\n<p><em>Dexafree eye drops dosage<\/em><\/p>\n\n\n\n<p>Always use this medicine exactly as your doctor has told you.&nbsp;Ask your doctor or pharmacist if you are unsure.<\/p>\n\n\n\n<p>The recommended&nbsp;<strong>Dexafree eye drops dosage<\/strong>&nbsp;is one drop 4-6 times daily in the eye to be treated.&nbsp;In severe cases, treatment can start with 1 drop every hour and&nbsp;dosage&nbsp;one can be reduced to 1 drop every 4 hours when a favorable response has been observed.&nbsp;Gradual reduction of&nbsp;dose&nbsp;one is recommended to prevent relapse.<\/p>\n\n\n\n<ul class=\"wp-block-list\"><li><strong>Elderly:<\/strong>&nbsp;No special&nbsp;dosing&nbsp;is required.<\/li><li><strong>Children:&nbsp;<\/strong>Continuous&nbsp;long-term treatment should be avoided.<\/li><\/ul>\n\n\n\n<p><strong>Instructions for<\/strong> <strong>Dexafree uses<\/strong><\/p>\n\n\n\n<p>Ocular&nbsp;use: Dexafree is intended for use in the eyes.<\/p>\n\n\n\n<ol class=\"wp-block-list\"><li><strong>Wash your hands<\/strong>&nbsp;thoroughly before using this medicine.<\/li><li>Drip&nbsp;<strong>one drop in the eye to be treated<\/strong>&nbsp;as you gaze upwards while pulling the lower eyelid down slightly.<\/li><li>Immediately after application,&nbsp;<strong>press lightly with the finger<\/strong>&nbsp;in the corner of the eye on the treated eye for a few minutes (to reduce the risk of general reactions and to increase the penetration of the active substance into the eye).<\/li><li><strong>Dispose of the<\/strong>&nbsp;single-dose&nbsp;container after use.&nbsp;You should not save it for later use.<\/li><\/ol>\n\n\n\n<p><strong>Repeated treatment<\/strong><\/p>\n\n\n\n<p>4-6 times daily.<\/p>\n\n\n\n<p><strong>Length of treatment<\/strong><\/p>\n\n\n\n<p>The duration of a treatment usually varies from a few days to a maximum of 14 days.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If You Use More Dexafree Than You Should&nbsp;<\/h2>\n\n\n\n<p>Rinse the eye with running sterile water if you have dropped too much of the Dexafree into your eye and you have been irritated for a long time.<\/p>\n\n\n\n<p>Contact a doctor or pharmacist immediately.<\/p>\n\n\n\n<p>If you have ingested too much medicine or if, for example, a child has accidentally ingested the medicine, contact a doctor, hospital, or the Poison Information Center for risk assessment and advice.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If You Forget To Use Dexafree<\/h2>\n\n\n\n<p>Do not use a double&nbsp;dose&nbsp;to make up for a forgotten&nbsp;dose.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">If You Stop Using Dexafree<\/h2>\n\n\n\n<p><strong>Do not end the treatment suddenly.&nbsp;<\/strong>Always consult your doctor if you are considering stopping treatment.<\/p>\n\n\n\n<p>If you have any further questions about the use of this product, ask your doctor or pharmacist.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">4. Possible  Dexafree Eye Drops Side Effects<\/h2>\n\n\n\n<p>Like all medicines, this medicine can cause&nbsp;side effects, although not everybody gets them:<\/p>\n\n\n\n<p><strong>Hormone disorders:<\/strong><\/p>\n\n\n\n<p><em>Has been reported Dexafree eye drops side effects (occur in an unknown number of users)<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Extra hair growth on the body (especially in women)<\/li><li>Muscle weakness and loss<\/li><li>Purple stretch marks on the skin<\/li><li>High&nbsp;blood pressure<\/li><li>Irregular or no <a href=\"https:\/\/zeepedia.com\/medical\/diseases\/menses\/\">menstruation<\/a><\/li><li>Changes in&nbsp;protein&nbsp;and calcium levels in the body<\/li><li>Growth inhibition in children and adolescents<\/li><li>Swelling and weight gain on the body and in the face (called Cushing&#8217;s syndrome, see section 2 &#8220;Warnings and Precautions&#8221;)<\/li><\/ul>\n\n\n\n<p><strong>Eye side effects:<\/strong><\/p>\n\n\n\n<p><em>Very common (may affect more than 1 in 10 people):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>High pressure in the eye, after two weeks of treatment.<\/li><\/ul>\n\n\n\n<p><em>Common Dexafree eye drops side effects (may affect up to 1 in 10 people):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Discomfort<\/li><li>Irritation<\/li><li>Burning<\/li><li>Tingling<\/li><li><a href=\"https:\/\/zeepedia.com\/medical\/diseases\/dry-skin-and-itching\/\">Itching<\/a><\/li><li>Blurred vision<\/li><\/ul>\n\n\n\n<p>&nbsp;These&nbsp;side effects&nbsp;are usually short-lived and mild.<\/p>\n\n\n\n<p><em>Uncommon (may affect up to 1 in 100 people):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Allergic and&nbsp;hypersensitivity reactions&nbsp;to any of the ingredients in the eye drops<\/li><li>Delayed healing<\/li><li>Lens haze (<a href=\"https:\/\/zeepedia.com\/medical\/diseases\/cataracts\/\">cataracts<\/a>,&nbsp;cataracts&nbsp;)<\/li><li>Infection<\/li><li>Glaucoma&nbsp;(&nbsp;glaucoma&nbsp;)<\/li><\/ul>\n\n\n\n<p><em>Very rare (may affect up to 1 in 10,000 people):<\/em><\/p>\n\n\n\n<ul class=\"wp-block-list\"><li>Inflammation&nbsp;of the&nbsp;conjunctiva of the eye&nbsp;(&nbsp;conjunctivitis&nbsp;)<\/li><li>Dilated&nbsp;pupil&nbsp;(&nbsp;mydriasis&nbsp;)<\/li><li>Facial swelling (facial edema)<\/li><li>Drooping eyelids (ptosis)<\/li><li>Inflammation&nbsp;of the&nbsp;iris&nbsp;(&nbsp;uveitis&nbsp;)<\/li><li>Calcification of the cornea<\/li><li>Inflammation&nbsp;of the cornea (crystalline&nbsp;keratopathy&nbsp;)<\/li><li>Differences in corneal thickness<\/li><li>Corneal edema<\/li><li>Corneal ulcer<\/li><li>Holes in the cornea<\/li><\/ul>\n\n\n\n<p>If you have severely damaged&nbsp;cornea,&nbsp;in very rare cases,&nbsp;phosphate&nbsp;can cause cloudy spots on the cornea due to the accumulation of&nbsp;calcium&nbsp;during treatment.<\/p>\n\n\n\n<h2 class=\"wp-block-heading\">5. How To Store Dexafree<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Keep <strong>Dexafree eye drops<\/strong> out of the sight and reach of children.<\/li><li>Do not use this medicine after the expiry date which is stated on the single-dose container after EXP.&nbsp;The expiration date is the last day of the specified month.<\/li><li>After opening the protective bag containing the single-dose containers: use the single-dose containers within 15 days.<\/li><li>Use the single-dose container immediately after opening it and discard it after use.<\/li><li>Store the single-dose containers in their original packaging.&nbsp;Sensitive to light.<\/li><li><em>Dexafree eye drops<\/em> should not be disposed of via wastewater or household waste.&nbsp;Ask your pharmacist how to dispose of medicines no longer required.&nbsp;These measures will help to protect the environment.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">6. Contents Of The Packaging And Other Information<\/h2>\n\n\n\n<h2 class=\"wp-block-heading\">Content Declaration<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>The active substance is dexamethasone sodium phosphate.&nbsp;One milliliter solution contains 1 mg dexamethasone phosphate (as dexamethasone sodium phosphate).<\/li><li>The other ingredients are <ul><li>Disodium edetate<\/li><li>Disodium phosphate dodecahydrate<\/li><li>Sodium chloride<\/li><li>Water for injections<\/li><\/ul><\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">What The Medicine Looks Like And The Contents Of The Pack<\/h2>\n\n\n\n<ul class=\"wp-block-list\"><li>Dexafree are clear colorless to pale brown&nbsp;eye drops, solution in&nbsp;single-dose containers.<\/li><li>Each&nbsp;single-dose&nbsp;container contains 0.4 ml of solution.&nbsp;The package contains 10, 20, 30, 50, or 100&nbsp;single-dose containers&nbsp;packed in sachets.<\/li><li>Not all packaging may be marketed.<\/li><\/ul>\n\n\n\n<h2 class=\"wp-block-heading\">Marketing Authorization Holder And Manufacturer<\/h2>\n\n\n\n<p><strong>Marketing Authorisation Holder:<\/strong><\/p>\n\n\n\n<p>Laboratories THEA<\/p>\n\n\n\n<p>12, rue Louis Bl\u00e9riot<\/p>\n\n\n\n<p>63017 Clermont-Ferrand Cedex 2<\/p>\n\n\n\n<p>France<br><\/p>\n\n\n\n<p><strong>Manufacturer:<\/strong><\/p>\n\n\n\n<p>Excelvision<\/p>\n\n\n\n<p>Rue de la Lombardi\u00e8re<\/p>\n\n\n\n<p>07100 Annonay<\/p>\n\n\n\n<p>France<\/p>\n\n\n\n<p>or<\/p>\n\n\n\n<p>Laboratory UNITHER<\/p>\n\n\n\n<p>ZI de la Gu\u00e9rie<\/p>\n\n\n\n<p>50211 Cedex Coutances<\/p>\n\n\n\n<p>France<br><\/p>\n","protected":false},"excerpt":{"rendered":"<p>Dexafree has dexamethasone, which is used to stop inflammatory symptoms such as pain, heat swelling, and redness. Dexafree is used to treat irritation of the eyes. <\/p>\n","protected":false},"author":2,"featured_media":36238,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"cybocfi_hide_featured_image":"yes","footnotes":""},"categories":[2204,2200],"tags":[5735,5738,5737,5713,5715,4501,2212,5736],"class_list":["post-7415","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-d","category-medicines","tag-dexafree","tag-dexafree-eye-drops","tag-dexafree-side-effects","tag-dexamethasone-phosphate","tag-dexamethasone-phosphate-side-effects","tag-eye-drops","tag-medicine","tag-what-is-dexafree"],"_links":{"self":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7415","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/comments?post=7415"}],"version-history":[{"count":65,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7415\/revisions"}],"predecessor-version":[{"id":36239,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/posts\/7415\/revisions\/36239"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media\/36238"}],"wp:attachment":[{"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/media?parent=7415"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/categories?post=7415"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/zeepedia.com\/medical\/wp-json\/wp\/v2\/tags?post=7415"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}